Researchers developed a fiber-like supercapacitor with high volumetric energy density, comparable to thin-film lithium batteries. The device offers fast charging and discharging capabilities, making it suitable for powering wearable medical monitors and communications equipment.
A Case Western Reserve University student and his mentor have discovered an ancient kitten-sized predator that lived in Bolivia about 13 million years ago. The animal would have been about the size of a marten and probably filled the same ecological niche as larger sparassodonts.
A study of over 16,000 patient visits found that physician practice facilitation led to significant improvements in pediatric preventive medical care delivery. Practices with early intervention saw a sixfold increase in obesity screening and a 20-fold increase in fluoride varnish application compared to those without intervention.
Researchers discovered that fatty acid binding protein 5 (FABP5) enhances cognitive function and improves learning and memory functions in the brain's hippocampus region. FABP5 deficiency impairs learning and memory, suggesting potential therapeutic applications for cognitive dysfunction.
A new study finds that climate change and urbanization are threatening Ohio butterflies, with eight species showing significant delays in lifecycle events. The findings suggest that these changes may render the species unfit for parts of the state, highlighting the importance of monitoring butterfly populations.
A $2.3 million study will analyze 20 Cleveland neighborhoods to understand the impact of neighborhood conditions, social services, and reporting processes on child maltreatment rates. The research aims to identify factors tied to reduced abuse and neglect, potentially highlighting new targets for interventions at the neighborhood level.
A study found that aspirin lowers colorectal cancer risk in people with high 15-PGDH gene levels, but not those with low levels. The research team analyzed data from nearly 128,000 participants and discovered a link between 15-PGDH and the anti-cancer effects of aspirin.
Researchers at Case Western Reserve University have developed a new method to isolate single immune cells from the mouth, allowing them to study how these cells fight diseases. The method successfully isolated over 94% of the cells, enabling researchers to gain insights into treating oral cancers and other health issues.
Scientists at Case Western Reserve University have discovered how MRP-14 generates dangerous clots that could trigger heart attack or stroke. MRP-14 binds to a platelet receptor called CD36 to activate platelets, promoting pathologic blood clotting.
Researchers at Case Western Reserve University have found a novel population of neutrophils that produce Interleukin 17 (IL-17) and exhibit enhanced microbial killing activity. These cells may contribute to both controlling infection and causing tissue damage, highlighting the need for further regulation.
Research suggests that a leader must be either analytical or empathetic, but not both at the same time. However, recent studies from Case Western Reserve University reveal that this distinction has a foundation in our brains, which allows us to switch between the two modes.
Students at both universities will learn to break into and protect hardware, software, and data through hands-on experiments. The program aims to educate future users, developers, and controllers of computer systems on how to defend against cyber attacks.
Using big data analytics, researchers can predict the type of breast, lung, or oropharyngeal cancers with high accuracy. This technology may enable doctors to use MRI scans to diagnose more aggressive cancers earlier, leading to faster treatment options and improved patient outcomes.
Scientists used MESSENGER spacecraft images and topographic data to build a comprehensive map of tectonic features on Mercury's surface. The findings indicate the planet has contracted between 4.6 and 7 kilometers in radius over its lifetime.
Scientists discovered that Pichia holds at bay a harmful fungal yeast Candida by secreting material that controls Candida's growth and biofilm formation. This finding holds promise for therapeutic agents to stave off not only thrush but also other life-threatening systemic fungal infections.
Researchers aim to create artificial platelets that can stick to injury sites and signal natural platelets to home in on them, offering a potential solution to bleeding disorders. The technology has broad applications in stanching bleeding and detecting diseases.
Researchers found that byproducts of two bacteria causing gum disease promote the growth of Kaposi's sarcoma-related lesions and tumors in the mouth. High levels of these bacteria are associated with periodontal disease, while healthy gums show lower levels.
AeroClay technology offers various applications, including packaging hazardous materials and oil-spill cleanup solutions. The partnership between Case Western Reserve University and Compadre enables faster commercialization of the eco-friendly material.
A small pilot study of 22 mothers found that an 'Resourcefulness' intervention, teaching coping skills, bolsters moms' mental health and improves family dynamics. The intervention reduced negative emotions and depressive cognitions in mothers caring for children on life-sustaining devices.
Researchers at CWRU develop technology to connect patient records, enabling tracking of patterns in patient outcomes and improved transfer decisions. The system integrates data from 42 areas, streamlining the process and allowing for faster analysis.
A new tool, Conjunctive Exploratory Navigation Interface (CENI), combines two search modes to provide a more focused search and retrieve the most pertinent information. CENI outperformed traditional keyword-based lookup interfaces in a study involving crowdsourced testers.
Researchers have discovered how the protein Bcl-2 signals cancer cells to live longer by altering calcium ion levels. This breakthrough could lead to new drugs targeting Bcl-2 and improve cancer treatment outcomes.
A new study by Case Western Reserve University finds that people with strong religious beliefs perceive a higher risk of addiction to online pornography, even if they only view it once. The researchers suggest that therapists can help individuals understand their driving motivations and enjoy their faith.
Researchers at Case Western Reserve University are converting the laser hot-wire welding process into a high-output 3D additive manufacturing process with partners Lincoln Electric and other industry leaders.
Researchers at Case Western Reserve University have developed a multifunctional nanoparticle that enables MRI to pinpoint blood vessel plaques caused by atherosclerosis. The technology is a step toward creating a non-invasive method of identifying vulnerable plaques in time for treatment.
A new study by Case Western Reserve University neuroscientists found that autistic children's brains produce more information when not actively engaging with the world. This excess information generation may explain their characteristic withdrawal into self, or introspection.
Researchers at Case Western Reserve University have found that individual cells in the hippocampus use small electrical fields to stimulate and synchronize neighboring cells, spreading activity layer by layer. This discovery suggests a possible novel target for seizure-blocking medicines.
Researchers at Case Western Reserve University found that rapid improvements in depression symptoms during PTSD treatments are associated with better outcomes. Negative social support from family or friends was also linked to worsening depression symptoms, while transient spikes did not negatively impact treatment progress.
The university's AIDS Clinical Trials Unit will conduct human studies to advance knowledge of HIV-related diseases, prevention, and treatment. The award supports the development of effective methods to prevent HIV infection and fine-tune treatments for patients, aiming to improve life expectancy and quality of life.
Researchers identified critical complex mechanisms involved in TNBC metastasis, including the interaction between WAVE3 and TGF-β proteins. The discovery has the potential to develop new treatments to kill metastatic tumors in TNBC, with the goal of moving into clinical trials within three years.
The researchers propose to build complex polymer nanostructures on scaffolds made of plant viruses to provide control and precision. They aim to produce an evenly dispersed polymer coating with consistent and efficient properties, reducing toxic side effects in drug delivery.
A research team, including Anthony Wynshaw-Boris and Shinya Yamanaka, successfully used induced pluripotent stem cell reprogramming to correct a defective ring chromosome with a normal one. This approach has potential to treat birth defects, mental disabilities, and growth limitations caused by chromosomal abnormalities.
Researchers at Case Comprehensive Cancer Center have identified a microRNA biomarker, miR-181a, that predicts treatment response in ovarian cancer. Elevated levels of miR-181a are associated with chemotherapy resistance and disease progression.
A new study from Case Western Reserve University finds that released inmates with severe mental illness prioritize basic needs like housing and food over mental health services. The study suggests that social workers and policymakers must ensure that both basic and treatment needs are met during the transition from jail to community.
Researchers at Case Western Reserve University are developing imaging technology to improve treatment and survival rates for ischemic heart disease patients. The new technology uses high-speed computer analysis to help doctors determine if stents are restoring circulation as designed, reducing the risk of failure.
Researchers discovered that six autoimmune diseases arise from DNA changes located outside genes. Multiple genetic switches controlling gene expression are affected in each disease, leading to incorrect gene expression. The study provides a new model for understanding the genetic causes of common complex diseases.
Researchers at Case Western Reserve University are working on a new device that can predict when patients with sickle cell disease will suffer an acute crisis and monitor the effectiveness of treatments. The device measures the physical properties of red blood cells, which become sticky and block blood flow during a crisis.
A team of researchers, including a scientist from Case Western Reserve University, have announced the discovery of a new species of fossil horse from 4.4 million-year-old deposits in Ethiopia. The newly named Eurygnathohippus woldegabrieli had three-toed hooves and grazed grasslands and shrubby woods.
Scientists have successfully restored behavior in rats using a neural prosthesis after brain injury. The device, a closed-loop microelectronic system, recorded signals from one part of the brain and stimulated another to facilitate repair. Two weeks after implantation, rat models recovered nearly all function lost due to injury.
Case Western Reserve engineers create nanoscale switches with low power consumption and durability, enabling faster and more efficient computing. The silicon carbide-based technology could lead to significant advancements in electronics and computing.
Research by Case Western Reserve University found that younger individuals with HIV are more likely to experience social isolation and stress due to stigma and limited support networks. In contrast, older adults with HIV were found to have developed social connections and coping mechanisms that helped mitigate these effects.
Researchers have discovered genetic mutations in Plasmodium vivax that may be causing a rise in infections among Duffy negative individuals. The mutations include a duplication of the Duffy binding protein and two new proteins that resemble those used by related malaria parasites to enter red blood cells.
A $1.4 million project led by CWRU psychologist Julie Exline aims to understand the factors behind religious and spiritual struggles. The study will explore how spiritual conflicts arise, resolve, and impact individuals from different life stages, including college students, US adults, and military veterans.
Researchers at Case Western Reserve University are working on an MRI-guided robotic heart catheter to accurately navigate and target tissues in the heart. The technology aims to reduce complications associated with current treatments for arterial fibrillation, allowing doctors to more precisely ablate the affected tissue and restore no...
The university's simulation program employs alumni with depression and substance abuse issues to provide students with real-life experience in simulated medical scenarios. This novel approach allows for one-on-one training before actual patients are encountered.
A new Case Western Reserve University study examines how ruptures in the therapeutic relationship between therapist and client can damage a patient's treatment outcome for PTSD. Researchers found that repairing these ruptures can have positive effects on treatment outcomes, while unresolved ruptures predict poorer outcomes.
Researchers at CWRU aim to build nanoparticles that can infiltrate and quash aggressive cancers that survive traditional therapy. They will perfect molecular coatings called ligands to enable nanochains to home in on micrometastases.
Researchers have identified a new way to determine precisely what portions of the brain suffer from epilepsy, improving surgical outcome accuracy and efficiency. Using intracranial electroencephalography, they found that patients' preoperative functional neural connectivity was strongly associated with successful surgery outcomes.
Case Western Reserve University researchers aim to develop processes that can be used by industry to manufacture Janus particles, which could carry paired medicines or provide unique optics for displays. The engineers focus on creating high-yield nanomanufacturing with simple processes.
Derek Taylor, a researcher at Case Western Reserve School of Medicine, has been awarded the NIH New Innovator Award to develop new methods for treating cancer. His research focuses on using telomerase as a 'Trojan horse' to deliver toxic compounds to cancer cells selectively.