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Duke University


Harnessing skin cancer genes to heal hearts

Researchers at Duke University successfully introduced a mutated BRAF gene into rat heart tissue, inducing growth and cell division. However, the approach was associated with significant loss of contractile strength, highlighting the need for precise control over gene activation and delivery.

SourceDuke University·JournalScience Advances·TypeExperimental study·DateJan 24, 2024

Traumatic stress associated with smaller brain region

A study from Duke University found that people with PTSD have a significantly smaller cerebellum, especially in areas related to emotion and memory. Researchers hope this discovery will lead to targeted treatments and more research on the brain region's role in PTSD.

SourceDuke University·JournalMolecular Psychiatry·TypeObservational study·DateJan 9, 2024

Protected areas for elephants work best if they are connected

A new study published in Science Advances suggests that protected areas for elephants are most effective when connected to allow populations to stabilize naturally. This approach, known as 'connecting parks,' enables herds to move freely and absorb immigrants, reducing the need for human intervention.

SourceDuke University·JournalScience Advances·TypeData/statistical analysis·DateJan 5, 2024

Wider access to antivenom in Brazil’s Amazon is a worthy investment

Making antivenom more widely available across hospitals and community health centers in the Brazilian Amazon region would significantly reduce death and disability from venomous snakebites. The study found that expanding access to both hospitals and community health centers would produce the largest benefits, averting up to 3,922 death...

SourceDuke University·JournalThe Lancet Regional Health - Americas·TypeData/statistical analysis·DateJan 3, 2024

Soundwaves harden 3D-printed treatments in deep tissues

A team of engineers has developed a novel printing method called deep-penetrating acoustic volumetric printing (DVAP) that uses soundwaves to solidify biologically compatible structures in deep tissues. The technique involves a specialized ink that reacts to ultrasound waves, enabling the creation of intricate structures for biomedical...

SourceDuke University·JournalScience·TypeExperimental study·DateDec 7, 2023

Brittle stars can learn just fine -- even without a brain

Researchers found that brittle stars, brainless marine creatures, can associate darkness with food and react accordingly, demonstrating classical conditioning. They retained this association even after a break from training, suggesting potential learning capabilities in these animals.

SourceDuke University·JournalBehavioral Ecology and Sociobiology·TypeExperimental study·DateNov 29, 2023

Seeing cancer’s spread through a computational window

Researchers at Duke University have developed a new computational model called Adaptive Physics Refinement (APR) that can simulate the movement of individual cancer cells across long distances within the entire human body. This approach captures detailed cellular interactions and their effects on cellular trajectory, providing valuable...

SourceDuke University·TypeExperimental study·DateNov 27, 2023

Measuring long-term heart stress dynamics with smartwatch data

Biomedical engineers at Duke University created a new 'digital twins' framework using smartwatch data to capture personalized arterial forces over 700,000 heartbeats. This approach reduces the computational load by simulating tasks in parallel, enabling real-time tracking of cardiovascular disease progression and risk assessment.

SourceDuke University·TypeExperimental study·DateNov 27, 2023

Brain implant may enable communication from thoughts alone

A new speech prosthetic developed by Duke neuroscientists and engineers can translate brain signals into spoken words, improving communication for people with neurological disorders. The device achieved an accuracy rate of 40% in predicting intended speech from 90 seconds of brain activity.

SourceDuke University·JournalNature Communications·TypeExperimental study·DateNov 6, 2023

What an animated taco reveals about curiosity and patience

A study by Duke neuroscientists found that curiosity increases people's patience for an answer while making them more eager to hear it. Curiosity also motivated viewers to withhold from hitting the 'spoiler' button and kept watching animated line-drawing videos unfold.

SourceDuke University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateOct 24, 2023

Endemic malaria found in high, dry northwestern Kenya

A new study by Duke University researchers has found endemic malaria in Turkana County, Kenya, with a significant incidence of Plasmodium vivax, a parasite historically rare in sub-Saharan Africa. The presence of invasive mosquito species Anopheles stephensi also poses challenges to the continent's malaria control efforts.

SourceDuke University·JournalEmerging Infectious Diseases·TypeObservational study·DateOct 12, 2023

Roundup ingredient connected to epidemic levels of chronic kidney disease

A Duke University study found glyphosate, active in Roundup, in high levels of wells supplying drinking water to Sri Lankan communities plagued by chronic kidney disease (CKDu). Elevated fluoride and vanadium also linked to CKDu were discovered. Glyphosate's persistence in hard water poses concerns for exposure.

SourceDuke University·JournalEnvironmental Science & Technology Letters·TypeExperimental study·DateOct 11, 2023

Unzipping mRNA rallies plant cells to fight infection

A new molecular mechanism has been identified that helps plants adjust protein levels to fight infection. By unzipping specific RNA structures, plant cells can produce defense proteins. This discovery also has implications for human cells, suggesting a similar mechanism may control protein production in response to pathogens.

SourceDuke University·JournalNature·TypeExperimental study·DateSep 20, 2023

Urban parks built on former waste incineration sites could be lead hotspots

A new study by Duke University found that urban parks built on former waste incineration sites can still contain high levels of lead in their surface soils, posing potential health risks to children. The research highlights the need for increased monitoring and mapping of contaminated soil hotspots across hundreds of cities.

SourceDuke University·JournalEnvironmental Science & Technology Letters·TypeObservational study·DateSep 11, 2023

Growing triple-decker hybrid crystals for lasers

By controlling the arrangement of multiple layers within crystals, researchers can tune the materials' optoelectronic properties and emit light of specific energies. This technique has significant implications for applications such as LEDs, solar cells, and lasers.

SourceDuke University·JournalNature Chemistry·TypeExperimental study·DateAug 31, 2023

Blink and you'll miss these plants shooting their seeds

Researchers found that witch hazel species with heavier seeds can fling them just as fast as lighter ones due to their spring-loaded fruits. The plants' unique mechanism involves the seed capsule drying out and deforming, releasing elastic energy to propel the seed forward.

SourceDuke University·JournalJournal of The Royal Society Interface·TypeExperimental study·DateAug 23, 2023

Microplastics found embedded in tissues of whales and dolphins

A study by Duke University researchers has found microplastics in the fats and lungs of two-thirds of marine mammals, suggesting that ingested plastics can travel into tissues. The presence of polymer particles and fibers in whales' fat and organs may cause harm, including hormone disruption.

SourceDuke University·JournalEnvironmental Pollution·TypeObservational study·DateAug 10, 2023

Synthetic antibiotic could be effective against drug-resistant superbugs

A new antibiotic strategy has been found to defeat gram-negative bacteria like Salmonella and E. coli by interfering with the outer lipid layer of the bacteria. The compound, LPC-233, is a small molecule that works fast and is durable in animal tests, with potentially vital applications against stubborn urinary tract infections.

SourceDuke University·JournalScience Translational Medicine·TypeExperimental study·DateAug 9, 2023

Eyes in the skies confirm the end of trash burning in the Maldives

A new AI approach has confirmed that the Maldivian government effectively enforced its ban on open trash burning and single-use plastics, eliminating toxic smoke plumes from satellite imagery. The tool, trained using transfer learning and image segmentation, achieved 88% accuracy in identifying plumes.

SourceDuke University·JournalEnvironmental Science & Technology Letters·TypeExperimental study·DateJul 13, 2023

Sticky, slippery, water repellent channels form maze-like, gravity-powered biomedical devices

Researchers at Duke University have developed a new approach to building point-of-care diagnostic devices that uses gravity to transport and mix liquid droplets. The device relies on commercially available surface coatings that can tweak the wettability and slipperiness of the channels, allowing for complex fluid paths to be designed.

SourceDuke University·JournalDevice·TypeExperimental study·DateJul 11, 2023

DNA barcoding identifies the plants a person has eaten

A new technique using DNA barcoding can identify the plant matter in human feces, improving clinical trials, nutrition studies and historical research. The method detected specific plant species and their relative amounts consumed, varying according to diet, age, and household income.

SourceDuke University·JournalProceedings of the National Academy of Sciences·TypeObservational study·DateJun 27, 2023

Do warmer temperatures make turtles better mothers?

New research from Duke University reveals that warmer temperatures increase the number of germ cells, which play a crucial role in determining the sex of turtles. This finding may explain why temperature-dependent sex determination persists in many animals, despite seeming like a risky strategy.

SourceDuke University·JournalCurrent Biology·TypeExperimental study·DateJun 23, 2023

The problems with coal ash start smaller than anyone thought

A new study by Duke University researchers reveals that the amount of toxic elements leaching out of coal ash depends largely on its nanoscale structure. The discovery highlights the complexity of coal ash as a material and emphasizes the need for closer examination of fine details within the ash to understand environmental risks.

SourceDuke University·JournalEnvironmental Science Nano·TypeExperimental study·DateJun 6, 2023

Little-known microbes could help predict climate tipping points

Researchers at Duke University have identified a climate feedback loop that could accelerate climate change. Monitoring mixotrophs, tiny organisms with dual metabolism modes, may allow us to anticipate the tipping point before it gets there. However, nutrient pollution poses a challenge to detecting early warning signals.

SourceDuke University·JournalFunctional Ecology·TypeComputational simulation/modeling·DateJun 1, 2023

Perfection: The Enemy of Evolution

Researchers discover allowing imperfection in design can create wider range of 'good enough' solutions, enabling more innovative designs. The study uses simple examples, such as walkways and bird flapping motion, to show that even small tolerances for imperfection open up significant design space.

SourceDuke University·JournalBiosystems·TypeObservational study·DateMay 18, 2023