Research analyzed data from nearly 1,000 participants born in the 1950s and 1960s, finding that children with overprotective fathers were more likely to die before age 80. Conversely, women who received better care from their mothers during childhood may experience a reduced risk of premature mortality.
Former Olympic-level gymnasts reported being subjected to coercive and repressive training methods, including obsessive weight control and restricted diets. The study highlights the need for a more balanced approach to athletic development, prioritizing athlete well-being over competitive success.
Researchers found that klotho has anti-inflammatory and neuroprotective effects on cultured glial cells, reversing increased secretion of pro-inflammatory cytokines. The study supports klotho's therapeutic potential in pathological processes with a neuroinflammatory component.
A study found that immune checkpoint inhibitors enhance chemotherapy-induced neuropathic pain by blocking interaction between macrophages and neurons via PD1-PDL1 synergy. This discovery could lead to the development of therapeutic alternatives to prevent pain while maintaining anti-neoplastic effects.
A study by researchers in Brazil found that loss of muscle mass during COVID-19 hospitalization is associated with the development of persistent symptoms such as weakness, shortness of breath, and fatigue. The study also showed that patients who lost more muscle mass had higher healthcare costs six months after discharge.
Researchers have developed a novel technique to produce hydrogen peroxide without releasing carbon dioxide, reducing greenhouse gas emissions. The method uses photocatalysis and carbon nitride as a catalyst, making it more cost-effective and environmentally friendly.
Researchers developed bioprinted artificial skin that mimics human skin, reducing animal testing in cosmetics and pharmaceutical industries. The model achieved similar results as traditionally produced models, passing international validation tests, including barrier function and irritant response assessment.
A study analyzing São Paulo City's built environment from 2015 to 2020 found that physical activity promoting structures increased, particularly in high-income areas. The growth varied by income level, with lower-income parts benefiting least from new bike paths and sports facilities.
Researchers identified hundreds of microorganisms associated with plant roots and soil, showing potential for developing biological substitutes for phosphorus-based fertilizers. The discovery highlights the importance of microbial communities in supplying essential nutrients like nitrogen.
Researchers at the University of São Paulo developed a portable, flexible copper sensor that can detect heavy metals like lead and cadmium in sweat. The device is made from ordinary materials and is simple to produce, making it accessible for non-specialists and technicians.
Researchers used density functional theory to investigate the mechanical properties of superionic ice XVIII, which is thought to make up a large part of Neptune and Uranus. The study found that dislocations in the crystal lattice produce shear, leading to macroscopic deformations and potentially influencing the planets' magnetic fields.
Researchers found a link between astrocytes from schizophrenic patients and reduced vascularization in the brain, which may contribute to the disease's metabolic flux. The study suggests that astrocytes could be a target for novel therapies to address schizophrenia.
Researchers found that larvae of the Atlantic mangrove fiddler crab survived less in warmer water and underwent physiological changes due to higher acidity. Marine heatwaves will be harmful to species and those that feed on them, with potential economic losses to fisheries. Further research is needed to understand the effects.
A study by researchers at the Federal University of São Carlos found that 86% of health workers reported burnout and 81% suffered from stress. They also experienced depression, slept badly, and complained of aches and pains. The study aimed to assess the effects of long working hours and burden on physical and mental health.
Researchers identified 92 proteins in the spider's venom, including cysteine-rich peptides with potential therapeutic applications. The toxins were found to be effective in paralyzing crickets and may become active ingredients for pharmaceuticals and biological insecticides.
Researchers found that the new law allowing goalkeepers to put one foot in front of the line improved their penalty diving performance. The study, led by Paulo Roberto Pereira Santiago, used 3D body reconstruction technology and motion capture to analyze dives.
A study of 665 pet dogs found that life history, owner gender, and breed can influence canine behavior. The results highlight the importance of environmental interactions in shaping animal behavior, suggesting that traits like weight, height, and cranial morphology impact the dog-owner relationship.
A survey of 3,021 people in Brazil found that Black women experience the highest rate of tooth loss, with a 26% higher proportion than white women. The study suggests that socioeconomic status and racism are major contributors to these disparities.
The São Paulo School of Advanced Science on Epidemic Preparedness will bring together researchers from various fields to discuss core tracks such as mathematical modeling, genomics, epidemiological surveillance, and public health policies. Participants will engage in simulated situation rooms and hands-on experience with leading faculty.
A six-year study involving 146 patients found that antivenom reduced the risk of skin necrosis in those bitten by brown recluse spiders. Administration of the substance was safe with minimal adverse effects, particularly when given within 48 hours of the incident.
Researchers found that dendritic cells in meninges produce mediators causing pain hypersensitivity after nerve injury. The kynurenine pathway, primarily driven by IDO1, is involved in pain production.
Researchers analyzed 300 oceanographic projects funded by FAPESP, revealing a shift from USP to other institutions. FAPESP's support for long-term projects and collaborative research has significantly increased knowledge of Brazilian oceans. Deep-sea research remains a gap to be filled, requiring further collaboration and funding.
Scientists successfully created a light source that produced two entangled light beams using rubidium atoms. The entanglement was achieved by adding new detection steps to measure the quantum correlations in the amplitudes and phases of the fields generated, enabling applications in quantum computing, encryption, and metrology.
The São Paulo School of Advanced Science on Stem Cell Biology will highlight the latest scientific advances in stem cell therapy and tissue bioengineering. Internationally renowned scientists will present state-of-the-art science and results of new research.
A study in Serrana, Brazil showed that mass vaccination reduced severe cases and death rates even while gamma and delta variants were circulating. Vaccination coverage reached 80% of the target population.
Research found that common anti-inflammatory drugs taken by children can alter the formation of dental enamel, leading to defects. The study's authors suggest potential harm from widespread use of these medications and plan to conduct a clinical trial to confirm findings in humans.
A study analyzed the potential of a bacterium to combat coffee rust, a major challenge for Brazilian coffee growers. The researchers found that the bacterium produces antibacterial and antifungal compounds, as well as proteins associated with protection against water stress, making it a promising candidate for biological control.
Researchers developed a method to estimate seroprevalence using blood donation samples, offering insights into the first year of the COVID-19 epidemic in Brazil. The study found significant differences among regions and subgroups, highlighting the need for real-time tracking and forecasting of future waves.
The São Paulo School of Advanced Science on Nanotechnology, Agriculture and Environment will cover topics such as nanotechnology innovation, sustainability, and biological applications. The event will feature renowned scientists as speakers and provide hands-on experiments, technical visits, and didactic activities.
Researchers developed AI-powered software to measure and classify pacu fish, enabling breeders to select animals with higher fillet yield and faster weight gain. The system uses deep learning and can recognize different parts of the fish even in challenging environments.
Physicians in Brazil's states of São Paulo and Maranhão used telemedicine for various purposes, including staff meetings, training sessions, and patient consultations. However, the technology has limitations and requires regulation to ensure quality care.
A survey of 5,500 Brazilian and Italian students aged 14-16 found that nationality, social perceptions of science, and household income were more influential than religion in rejecting evolutionary theory. The study published in PLOS ONE reveals a significant gap in understanding geological time between Italian and Brazilian Catholics.
A review of over 100 scientific articles suggests that the safety of antidepressants during pregnancy is endorsed by science, but their effects on fetal neurodevelopment are poorly understood. Brazilian researchers propose using lab-grown mini-brains to investigate this impact and identify potential alterations.
Researchers found that vitamin D deficiency increases the risk of dynapenia, an age-associated loss of muscle strength, by 70-78%. Vitamin D supplementation was shown to reduce this risk. The study analyzed data from over 3,000 individuals aged 50 and over, highlighting the importance of vitamin D for maintaining muscle strength.
A study suggests that visceral fat cells, rather than subcutaneous fat cells, are more susceptible to infection by the COVID-19 virus. This increased susceptibility leads to a higher viral load and production of pro-inflammatory cytokines, which can exacerbate severe disease.
Researchers identified a genetic variant linked to digestive disturbances in patients with Chagas megaesophagus, a disorder characterized by esophageal dilation and loss of motility. The study suggests that increased interferon-gamma production leads to mitochondrial dysfunction, contributing to the development of the disease.
A study conducted in Brazil reveals that only 75.8% of under-fifteen children in São Paulo have antibodies against measles, falling short of the ideal 94% target to prevent outbreaks. The finding is a warning sign that Brazilian children are not achieving herd immunity, making them susceptible to infection.
Conservation efforts in Madagascar require balancing human development with protection of its rich biodiversity, which is threatened by extinction due to local species' uniqueness. Reforestation and community engagement are recommended strategies for addressing these challenges.
A post-pandemic outbreak of a drug-resistant fungus in Brazil was linked to the misuse of medications and full ICUs. The study found that 90% of infected patients had strains resistant to fluconazole and echinocandins, leading to high mortality rates.
A Brazilian team developed an electrochemical immunosensor to detect SARS-CoV-2 antibodies, achieving 88.7% sensitivity and 100% specificity in just five minutes. The device can be adapted for other diseases and has potential for monitoring seroconversion and seroprevalence.
Researchers found an imbalance in an important immune system signaling pathway associated with severe COVID-19. They detected dysregulation of the immune system mediated by ATP, leading to a pro-inflammatory state and potentially fatal systemic inflammation.
Researchers developed an AI model to analyze spatial and temporal gait parameters, identifying key features for diagnosing Parkinson's. The model achieved high diagnostic accuracy, reducing the probability of error in clinical assessments.
Researchers have identified genetic variants associated with natural resistance to SARS-CoV-2, including a gene linked to mucin production. These findings may help develop vaccines and treatments for viral diseases by understanding the mechanisms underlying immune responses.
Researchers found that food hardness and tool size do not always correlate as closely as thought. Cultural learning plays a significant role in the tool choice of bearded capuchin monkeys, with some populations using disproportionately heavy tools for certain foods.
Researchers found that summer rainfall and autumn-winter dry days are increasing, leading to fluvial discharge and sediment load in rainy seasons and water deficits in dry seasons. The Pantanal's complex geomorphology, including mega-fans and self-affine landforms, makes it susceptible to anthropic interference.
The study analyzed experimental parameters, nanomaterial types, and plant exposure duration. It found that many studies lacked positive controls and had short durations compared to crop lifecycles.
Researchers found that SARS-CoV-2 increases methylation of host cell RNA, which can help the virus evade the immune system. This discovery provides insights into how different variants escape immunity and offers potential avenues for novel COVID-19 treatments.
Researchers found that female tiger sharks that frequently visit Tiger Beach in the Bahamas are larger and have higher hormone levels than other individuals. The study suggests possible effects of mass tourism on these sharks, with females having better nutritional states and more omega-3 in their blood.
A recent study analyzing Amazon Rainforest fires from 2003-2020 reveals that most fires are caused by uncontrolled human use of fire for agriculture and deforestation. The study found that Brazil accounted for an average of 73% of detected fires, with pasturelands and natural grasslands being the main burned areas.
Researchers developed an isothermal chemical vapor transport (ICVT) method for growing high-quality monocrystals without temperature gradients. This technique simplifies the growth process and produces crystals with excellent crystallographic quality.