Researchers developed a vertical drawing technique to fabricate intricate micro/nano optical fibers with tailored geometric precision. The approach enables meticulous control over diameter transitions and unlocks new possibilities for manipulating light-matter interactions, including supercontinuum generation.
Researchers develop serial tissue optical clearing methods to image neuro-vasculature of whole organ in mouse, enabling study of larger animal models like pigs and non-human primates. The technique facilitates the study of organ development and disease mechanisms in models closer to humans.
A new study introduces an innovative PCML-based hybrid modeling framework for steam thermal cracking, reducing computational demand and optimizing economic benefits and CO2 emissions. The approach achieves a 28.97% profit reduction and 42.89% CO2 emission decrease, with significant implications for sustainable chemical production.
A new multi-scale graph neural network overcomes limitations of traditional methods, achieving improved prediction accuracy and reduced overfitting. The model's attention mechanism enables interpretable predictions, highlighting key features such as Zn–O bonds.
A recent review highlights the potential of particle vision analysis (PVA) to accelerate discovery and quality control in nanomanufacturing, biomanufacturing, and pharmaceuticals. PVA integrates AI-based methods for classification, detection, segmentation, tracking, and super-resolution to analyze microscopic particles, which determine...
An online monitoring system for farmland non-point source pollution uses a serial pipeline to monitor continuous cropping farmland. The system breaks through limitations of existing technologies, providing real-time data and automated sampling.
China has made significant technological breakthroughs in stabilized fertilizers, increasing nitrogen use efficiency by over 50% while reducing losses and greenhouse gas emissions. Field trials have verified the comprehensive benefits of these products, including increased crop yields and reduced fertilizer usage.
Sugarcane intercropping improves soil health by breaking up compacted soil, enhancing nutrient use, and promoting microbial diversity. Practical cases in southern China show expanded applications with legumes, maize, vegetables, and green manure crops, improving land use efficiency and organic matter content.
China's farmland exhibits a dual characteristic of strong emissions and weak carbon sink, but optimizing management can reduce emissions by 11.6 Tg CO2-eq per year. Implementing '4R nutrient management' and improved irrigation techniques can increase soil organic carbon content and enhance carbon sequestration capacity.
Research finds that Akkermansia muciniphila alleviates hepatic fibrosis through propionate-driven antioxidant defense, improving liver function and reducing extracellular matrix accumulation. The study suggests a potential microbiota-based therapeutic strategy to combat liver fibrosis.
The study quantified emissions of four pollutants from agricultural production and domestic sewage in the Haixi area, revealing rural domestic sewage was main contributor to NH3-N. The research suggests promoting low-pollution modes, strengthening sewage pipe networks, and using comprehensive treatment technology for livestock breeding.
Researchers developed nitrogen-responsive promoters in Bacillus licheniformis, enabling expression systems to respond to changing nitrogen conditions. The newly identified promoters were found to initiate transcription and mediate transglutaminase gene expression, improving industrial production efficiency.
Multimodal AI fuses information from various sources, such as echocardiography and genomics, to deliver patient-specific insights and improve diagnostic performance. The technology can also refine treatment selection and predict patient outcomes, enabling targeted prevention strategies.
A new open-source tool estimates lifetime costs of green-hydrogen production with 95% probability, providing decision-makers with confidence intervals for bankable projects. The tool accounts for uncertainty in material prices, BoP costs, recycling rates, labor rates, and energy tariffs.
Researchers at Peking University have created a compact WGM microprobe for high-sensitivity ultrasound detection, achieving a remarkable noise-equivalent pressure of 5.4 mPa/√Hz. The device successfully performed photoacoustic imaging on various samples, including biological and synthetic microparticles.
Researchers found a higher burden of rare variants in Chinese patients with hypertrophic cardiomyopathy, with specific mutations common to the cohort. The study suggests ethnicity-specific genetic databases and refined interpretation frameworks improve diagnostic clarity for HCM management across diverse populations.
Researchers engineered Escherichia coli to produce inosinic acid, a popular umami enhancer, with significantly increased yields. The engineered strain produced 562.0 mg/L of IMP, a 4.77-fold increase over the wild-type strain.
The study found that the reduction in grain consumption was the primary reason for the decline in zinc intake. Zinc obtained from grains decreased significantly, while meat consumption only partially offset this impact. Regional differences were also observed, with certain provinces experiencing higher rates of insufficient zinc intake.
The study identifies two distinct neuronal populations affected by Alzheimer's disease: EC-stellate neurons lost and GFAP⁺ neurons expanding with glia-like features. These findings highlight energy metabolism dysfunction and neuronal identity changes in AD progression.
Secreted proteins offer promising therapeutic avenues for metabolic dysfunction-associated steatotic liver disease (MASLD). Recent research highlights their potential as therapeutic targets, but translating preclinical findings into effective clinical treatments remains challenging.
Researchers developed a novel catalyst using ultrasmall palladium nanoparticles supported on zirconium phosphate, achieving enhanced electrochemical reduction of CO2 to ethanol. The breakthrough increases the Faradaic efficiency to 92.1% for ethanol production.
Scientists established intrahepatic cholangiocyte organoids from Syrian hamsters, which withstand cooling-rewarming stress better than mouse-derived counterparts. shICOs maintain lower ROS levels and lipid peroxidation under cold exposure through enhanced anti-ferroptosis ability.
A recent study used machine learning to identify distinct COPD patient clusters in China, highlighting the impact of comorbidities on health-related quality of life. The analysis identified four clusters with varying characteristics, such as age, sex, and comorbidity profiles, which were associated with differences in health outcomes.
Researchers discovered a new reductive uric acid pathway that functions without oxygen, which builds upon current knowledge of uric acid degradation. The study found that this pathway produces a metabolite called yanthine, which is elevated in patients with gout and could serve as a biomarker for diagnosing or monitoring the condition.
This study reveals the complex relationships between rheumatoid arthritis and various organs, including the cardiovascular, respiratory, and gastrointestinal systems. The findings suggest that RA functions as a hub within an expansive web of interacting disorders.
Researchers have developed a new multifunctional catalyst for hydrogen evolution and alcohol oxidation, achieving superior performance and durability compared to commercial counterparts. The submonolayered Ru modification enhances atomic utilization efficiency and facilitates water adsorption, dissociation, and hydrogen desorption.
Researchers explore the role of atomically thin materials in single-atom catalysts for electrocatalytic water splitting, highlighting their potential for high performance and mechanistic insights. The study proposes a design framework for developing next-generation electrocatalysts with precise metal-support interactions.
The study introduces a new approach to enhance energy density in sodium-ion batteries by introducing flexible Al-O bonds into P2-type layered oxides. This strategy successfully suppresses irreversible phase transitions and stabilizes local structures, significantly improving sodium-ion diffusion kinetics.
Researchers analyzed high-temperature solid oxide electrolysis cells (SOECs) for CO₂ conversion, categorizing mechanisms into oxygen ion-conducting (O-SOECs) and proton-conducting (H-SOECs). They identified key global manufacturers and market trends, outlining pathways for efficient CO₂ conversion and energy storage.
Researchers explore innovative food processing technologies to enhance nutrient utilization efficiency in staple crops. These methods can retain more nutrients and reduce anti-nutritional factors, improving food safety and quality.
A study proposes a sustainable production pathway to achieve an annual yield of 22.5 t·ha<sup>–1</sup> on the North China Plain, improving soil quality and nutrient use efficiency while reducing resource input. Collaborative innovation between scientists and farmers has shown effective results in promoting technology promotion.
Researchers developed a technical framework for green wheat production, including soil, root zone, and canopy systems. The study found that combined application of organic fertilizer and mineral fertilizer can increase soil organic carbon sequestration efficiency by 26% and wheat yield by 15.1%.
Chinese researchers have developed a green high-yield and high-efficiency technology system for rice production, balancing yield and ecology. The new technology improves nitrogen use efficiency by 8.1%–21.3%, reduces greenhouse gas emissions, and enhances soil fertility.
Researchers discovered S100A12 and MCEMP1 as biomarkers for both ankylosing spondylitis and myocardial infarction, showing robust diagnostic performance. These genes are linked to chronic systemic inflammation and acute coronary thrombo-inflammation, making them potential targets for risk stratification and repurposing existing drugs.
Researchers have developed three green technologies to increase rice yield while reducing resource consumption. These include AWMD irrigation, a nitrogen fertilizer application technology, and a water-nitrogen coupling regulation technology that optimizes soil moisture and nutrient content. Trials have shown significant improvements in...
Researchers propose a green production scheme to balance high yield with efficient resource utilization in corn production. The study suggests three optimization strategies: matching planting density with solar radiation, selecting compact varieties, and optimizing tillage, root systems, and canopy. Implementing these schemes can incre...
Researchers proposed a quantitative design theory and technical pathway for green yield increase and efficient nitrogen utilization in winter wheat. The "Three-Stage Theory" identifies key bottlenecks and recommends optimizing population structure, soil health, and root-crown interactions to overcome them.
The study identifies core limiting factors in each region, including climate, soil conditions, and planting practices. A regionalized technical model is proposed to optimize planting density, nutrient management, and agronomic measures, resulting in improved yield and resource use efficiency.
A study analyzed 311 Chinese patients with Fabry disease, revealing correlations between enzyme activity, genotype, and clinical symptoms. Males with low residual enzyme activity are at higher risk of early multiorgan damage, while females and late-onset males present milder phenotypes.
This innovative approach optimizes the soil-crop-microbe system to achieve high yield, efficiency, and low pollution. By adopting green technology, China has increased food production by 21-87% while reducing nitrogen fertilizer inputs and greenhouse gas emissions.
A novel online hidden Markov model predicts geological risks in tunnels by integrating data from borehole samples and continuous observations. This approach offers timely hazard alerts and improved predictive accuracy compared to traditional methods, making it a valuable tool for safeguard tunneling operations.
This study develops an extreme high-temperature weather index to predict INE crude oil futures prices, finding improved accuracy with the index. Machine learning models are also made more explainable to provide insights into their predictive mechanisms.
This new method combines top-down and bottom-up approaches to address the challenge of increasing grain production while reducing pollution. The 'Technology Backyard' serves as a problem collection station and testing ground for technologies developed in collaboration with frontline producers.
The study reveals that China's green technology innovations have improved crop yields and reduced fertilizer use by 40% and 0.83 million tons, respectively. The researchers propose four strategies to address challenges and predict significant increases in food output by 2050.
The nuclear phosphoinositide-p53 signalosome modulates AKT activation in the nucleus, integrating two oncogenic pathways into a unified mechanism driving cancer cell motility. This complex is highlighted as a central regulator of cancer cell migration and a promising target for metastasis therapy.
The study resolved cryo-EM structures of the Nipah virus polymerase complex, unveiling binding modes between RdRp/PRNTase domains and the P tetramer. Two conserved zinc-binding sites were identified essential for polymerase activity.
Researchers investigate regional-specific gut microbial distribution, revealing its critical role in metabolic and immune regulation. Key findings include duodenal mucosal resection reducing small intestinal bacterial overgrowth and machine learning integrating multi-omics data to predict microbial dynamics.
Researchers aim to widen ADCs' therapeutic window and application scope by integrating AI, single-cell sequencing, and combination therapies. Precise antigen selection is crucial to minimize toxicity and improve efficacy in targeted cancer therapy.
Dynamin 1 regulates EMT progression, cell polarity and migration through N-cadherin endocytosis and recycling, promoting ovarian cancer metastasis. The study identifies DNM1 as a critical regulator of EMT-associated metastasis.
Lactic acid regulates tumor-immune crosstalk through pH control, G-protein-coupled receptor signaling, and post-translational modification. Therapeutic counter-strategies cluster into three themes: glycolytic restriction, immune-potentiating combinations, and metabolic repurposing to enhance antitumor cytotoxicity.