Rehabilitation psychologists argue that avoiding the term 'disability' has unintended consequences, including reinforcing negative attitudes. They advocate for reclaiming the term as a valued aspect of diversity and identity, and encourage others to normalize its use.
Researchers found a critical structure within TDP-43 that causes nerve cell death in ALS and FTD. Modifying this structure could lead to new therapies for these devastating diseases.
Researchers have discovered that amplifying the amount of VGLL3 in skin cells pushes the immune system into overdrive, leading to autoimmune responses. This finding may help explain why women are more likely to develop autoimmune diseases like lupus and could lead to new treatments.
A new tool, TBI-CareQOL Measurement System, standardizes the measurement of physical, mental and emotional effects experienced by caregivers of people with TBI. The researchers' findings could inform clinical care, caregiver training and support programs, and even caregiver reimbursement policies.
A new study found that nearly a third of hospital room surfaces had antibiotic-resistant bacteria on them, suggesting rapid transmission from patients to their environment. The research team suggests expanding hand hygiene efforts to include patients, as healthcare workers' hands remain the primary mode of microbe transmission.
A new study finds that an enzyme involved in liver function also triggers a protective response when liver cells are damaged. By boosting the levels of this enzyme, researchers hope to develop new treatments for acute liver injury.
A new CRISPR-Cas3 tool has been developed for long-range DNA editing in human cells, allowing scientists to target and delete large expanses of DNA. This technique harnesses a different type of CRISPR system than the widely used Cas9 tools, enabling precise control over DNA degradation.
A pilot study conducted in Kenya identified a safe and effective strategy to help women with HIV have children, despite the infection being passed on to their babies. The study showed six live births without HIV transmission among 23 couples participating in timed vaginal insemination.
A clinical trial shows promise of an immune-based therapy, which completely eliminated both the lesion and underlying HPV infection in a third of women enrolled. The shot triggers an immune system response to attack high-risk HPV types causing cervical cancer precursors.
A new national poll found that 55% of adults aged 50-80 have a pet, which reduces stress, gives them purpose, and encourages physical activity. However, some pet owners may prioritize their animals' needs over their own health.
A prototype wearable device can continuously collect live cancer cells directly from a patient's blood, offering a biopsy alternative. This innovation could help doctors diagnose and treat cancer more effectively by providing better information for planning treatments.
A new study suggests that giving surgery patients disposal bags to safely dispose of leftover opioids can double the percentage of patients who properly dispose of their unneeded pills within six weeks. The study showed that providing only an informational brochure had a much smaller effect on safe disposal rates.
Researchers found that tumor-associated macrophages release compounds that block the action of gemcitabine in malignant cells. The study suggests that patients with fewer macrophages in their tumors may respond better to chemotherapy. This discovery could lead to new approaches for treatment.
A national study reveals that young and middle-aged adults with hearing loss are twice as likely to misused prescription opioids and other substances compared to their hearing peers. Health care providers may need to take special care when treating pain and mental health conditions in deaf and hard-of-hearing patients.
A new study by Michigan Medicine found that parents and toddlers interact less with electronic books compared to print books, leading to reduced verbalization and quality of interactions. Parents tend to focus on technology rather than the story, hindering parent-guided conversation.
A recent University of Michigan-led study found that mothers of fussy babies are at a higher risk of experiencing depressive symptoms. The study explored whether a baby's level of prematurity in combination with infant fussiness influences the severity of maternal depressive symptoms.
Researchers discovered that knocking out NLRP6 protein in mice led to better survival and less severe symptoms after bone marrow transplant. The study also found that NLRP6 played a non-microbiome dependent role in GVHD, suggesting potential therapeutic targets for reducing its effects.
The International Registry of Acute Aortic Dissection (IRAD) has gathered data from 9,000 patients, revealing nearly 90% of type A dissections now receive surgical repair. In-hospital mortality is down to 16.3%, and five-year survival remains around 85%. IRAD also shows improved outcomes for type B dissections with endovascular therapy.
A non-invasive imaging biomarker called Parametric Response Mapping (PRM) can identify small airway damage in Chronic Obstructive Pulmonary Disease (COPD). This technique measures lung density during inhalation and exhalation, helping to predict patients who will lose lung function.
A new national poll reveals that one in four older adults experience feelings of loneliness, with those aged 50-80 who have health issues being most affected. Poor physical and mental health, hearing loss, and unhealthy habits are associated with a lack of companionship and feeling isolated.
A Michigan Medicine study reveals that combining aspirin with warfarin increases the risk of major bleeding events. The study found that nearly 2,500 patients were taking both medications without a clear reason, and that clinicians should review medical history to determine if it's necessary.
Despite the risks, many health care workers do not use recommended personal protective equipment when handling chemotherapy. A study from Michigan Medicine found that nurses who reported handling hazardous drugs had twice the risk of reproductive problems.
A new Michigan Medicine study found that long-term opioid use by one or more family members was associated with persistent opioid use by adolescents prescribed opioids after common surgical and dental procedures. The research highlights the potential risks of young adults continuing opioid prescriptions long after their surgeries.
A new study from Michigan Medicine reveals that pesticide exposure contributes to faster progression of amyotrophic lateral sclerosis (ALS). The research, published in the Journal of Neurology, Neurosurgery and Psychiatry, found that patients with higher levels of pesticides in their blood had a shorter median survival time.
A recent study has investigated the regulation of genes by noncoding DNA, which controls gene expression and determines cellular function. The research found that cell-specific enhancers have relatively small effects on target genes, highlighting the importance of tight regulation under normal conditions.
Researchers discovered that inhibiting the cancer-causing protein EZH2 can correct increased fibrosis and abnormal blood vessel function in scleroderma patients. This breakthrough suggests that existing EZH2 inhibitors could be repurposed to treat scleroderma, offering new hope for this currently incurable disease.
Researchers used a mouse model to isolate stem cells in rotator cuff muscles and calf muscles, finding that rotator cuff stem cells develop into fewer muscle cells and more fat cells. DNA-level studies revealed genes involved in fat metabolism were activated in rotator cuff muscle stem cells.
A new study suggests the Affordable Care Act's requirements on pre-existing conditions and age clauses had a significant impact on adults with diabetes. The percentage of people with private health insurance who had diabetes increased after the ACA provisions began, especially among those in their 50s.
A new study found that hospitals have reduced fluoroquinolone prescribing in-house, but one-third of patients still received discharge prescriptions for these high-risk antibiotics. The risk of side effects, including drug-resistant infections and tendon ruptures, increases with outpatient use.
A genetic mutation in glioma tumors makes them resistant to radiation treatment, but a new study suggests that currently available drugs can restore sensitivity. This breakthrough could lead to extended survival and improved treatment options for patients with low-grade gliomas.
A new study found that up to one-third of primary care physicians discussed breast cancer treatment options with patients. However, many reported notable gaps in their knowledge of these topics. The research highlights the importance of educating primary care providers on cancer treatment options and supporting them in making informed ...
A Michigan Medicine-led study found that increased hours of education related to caring for transgender patients does not correlate with improved knowledge among physicians and other providers. Transphobia was the only predictor of provider knowledge, highlighting the need for medical education to address unconscious bias.
Researchers have cataloged circular RNA in multiple cancers and identified it as a potential biomarker for diagnosis and prognosis. The stable structure of circRNA makes it an ideal candidate for detecting cancer in blood or urine samples.
Researchers found that young adults who received extra adult support as suicidal teens had a reduced risk of dying, with six-fold higher death rates among those without support. The study suggests the YST intervention may have long-term positive effects on mental health outcomes.
A new study found that most medical marijuana users in the US are treating chronic pain, with 85.5% of patients reporting an evidence-based condition. The study analyzed data from states with legalized medical use of marijuana and found a dramatic increase in patient numbers over time.
Cell lines, created from donated tissue samples, require unique considerations when creating research protections due to their value and expertise involved. The new Common Rule may pose unintended consequences for this resource, potentially disrupting scientific progress in cancer research.
Researchers successfully recreated microscopic networks of fibers made of DNA, called NETs, in the laboratory. The study found that these microwebs can capture and kill bacteria, potentially leading to more effective antibiotics and a new approach to treating infections.
A recent study found nearly one-third of women under 40 underwent mammography before breast reduction surgery, despite guidelines recommending against it. The screenings can lead to unnecessary follow-up tests and treatments, wasting time and money.
A new study finds an association between lengthy periods of maternal sleep and late stillbirths, independent of other risk factors. Further research is needed to understand the relationship and its implications for pregnant women.
A new study found that acupressure significantly improved chronic pain, anxiety, depression, and poor sleep in breast cancer survivors experiencing fatigue. Researchers tested two types of acupressure and found relaxing acupressure to be more effective for depressive symptoms and sleep.
A new study found that nearly a quarter of antibiotic prescriptions for children and adults may be unnecessary, with 1 in 7 patients receiving antibiotics for cases that were not medically justified. This highlights the need to reduce antibiotic overuse and its consequences, including contributing to antibiotic-resistant bacteria.
A new survey of first-year internal medicine residents found that those in programs with longer hours, less faculty mentoring, and more research focus had higher depression scores. The study suggests that institutions and residency programs play a critical role in resident mental health.
A new study found that more than half of medical cannabis users drive under the influence within two hours of use, with one in five driving 'very high'. The researchers urge for clearer guidelines and public education to increase awareness of cannabis-related driving impairment.
A partnership between Kellogg Eye Center and the University of Michigan used radio-frequency identification (RFID) to track patient wait times and enhance time spent at the doctor's office. The smart clinic model improved efficiency and boosted transparency, allowing doctors to monitor patients' movements and provide timely reassurance.
A new review by Michigan Medicine researchers shows that opioids are a key contributor to the rise in suicides and drug overdoses in the US. The study calls for improvements in pain care, mental health care, and medication-assisted opioid addiction care to reverse this deadly trend.
A new study finds that genetic testing for breast cancer does not cause excessive anxiety, even with ambiguous results. Researchers surveyed 1,063 women and found that the type of test or result did not significantly impact worry levels.
A new national poll suggests that many people in their 50s and early 60s harbor serious worries about their health insurance status, now and in the future. The poll found that 45% of those age 50-64 concerned they won't be able to afford insurance in retirement.
A genomic duplication in Caucasians could contribute to the high incidence of esophageal adenocarcinoma. Researchers found that African-Americans have a protective genetic variant, GSTT2, which may help prevent cancer. Flavonoids derived from cranberries show promise as a potential chemoprevention agent.
A new study reveals that firearm-related deaths are the second leading cause of death among US children and teens, accounting for over 60% of preventable deaths. The rate of firearm-related death remains persistent, with over eight children dying daily, and disproportionately affects urban adolescents and African-American youth.
A new study published in BMJ found that primary care doctors need to work six more hours a day to provide recommended preventive care, including colonoscopy and lung cancer screening. The simulation model also reveals that this would lead to 17 out of every 100 doctors taking early retirement each year.