The International Registry of Acute Aortic Dissection (IRAD) has gathered data from 9,000 patients, revealing nearly 90% of type A dissections now receive surgical repair. In-hospital mortality is down to 16.3%, and five-year survival remains around 85%. IRAD also shows improved outcomes for type B dissections with endovascular therapy.
A non-invasive imaging biomarker called Parametric Response Mapping (PRM) can identify small airway damage in Chronic Obstructive Pulmonary Disease (COPD). This technique measures lung density during inhalation and exhalation, helping to predict patients who will lose lung function.
A new national poll reveals that one in four older adults experience feelings of loneliness, with those aged 50-80 who have health issues being most affected. Poor physical and mental health, hearing loss, and unhealthy habits are associated with a lack of companionship and feeling isolated.
A Michigan Medicine study reveals that combining aspirin with warfarin increases the risk of major bleeding events. The study found that nearly 2,500 patients were taking both medications without a clear reason, and that clinicians should review medical history to determine if it's necessary.
Despite the risks, many health care workers do not use recommended personal protective equipment when handling chemotherapy. A study from Michigan Medicine found that nurses who reported handling hazardous drugs had twice the risk of reproductive problems.
A new Michigan Medicine study found that long-term opioid use by one or more family members was associated with persistent opioid use by adolescents prescribed opioids after common surgical and dental procedures. The research highlights the potential risks of young adults continuing opioid prescriptions long after their surgeries.
A new study from Michigan Medicine reveals that pesticide exposure contributes to faster progression of amyotrophic lateral sclerosis (ALS). The research, published in the Journal of Neurology, Neurosurgery and Psychiatry, found that patients with higher levels of pesticides in their blood had a shorter median survival time.
A recent study has investigated the regulation of genes by noncoding DNA, which controls gene expression and determines cellular function. The research found that cell-specific enhancers have relatively small effects on target genes, highlighting the importance of tight regulation under normal conditions.
Researchers discovered that inhibiting the cancer-causing protein EZH2 can correct increased fibrosis and abnormal blood vessel function in scleroderma patients. This breakthrough suggests that existing EZH2 inhibitors could be repurposed to treat scleroderma, offering new hope for this currently incurable disease.
Researchers used a mouse model to isolate stem cells in rotator cuff muscles and calf muscles, finding that rotator cuff stem cells develop into fewer muscle cells and more fat cells. DNA-level studies revealed genes involved in fat metabolism were activated in rotator cuff muscle stem cells.
A new study suggests the Affordable Care Act's requirements on pre-existing conditions and age clauses had a significant impact on adults with diabetes. The percentage of people with private health insurance who had diabetes increased after the ACA provisions began, especially among those in their 50s.
A new study found that hospitals have reduced fluoroquinolone prescribing in-house, but one-third of patients still received discharge prescriptions for these high-risk antibiotics. The risk of side effects, including drug-resistant infections and tendon ruptures, increases with outpatient use.
A genetic mutation in glioma tumors makes them resistant to radiation treatment, but a new study suggests that currently available drugs can restore sensitivity. This breakthrough could lead to extended survival and improved treatment options for patients with low-grade gliomas.
A new study found that up to one-third of primary care physicians discussed breast cancer treatment options with patients. However, many reported notable gaps in their knowledge of these topics. The research highlights the importance of educating primary care providers on cancer treatment options and supporting them in making informed ...
A Michigan Medicine-led study found that increased hours of education related to caring for transgender patients does not correlate with improved knowledge among physicians and other providers. Transphobia was the only predictor of provider knowledge, highlighting the need for medical education to address unconscious bias.
Researchers have cataloged circular RNA in multiple cancers and identified it as a potential biomarker for diagnosis and prognosis. The stable structure of circRNA makes it an ideal candidate for detecting cancer in blood or urine samples.
Researchers found that young adults who received extra adult support as suicidal teens had a reduced risk of dying, with six-fold higher death rates among those without support. The study suggests the YST intervention may have long-term positive effects on mental health outcomes.
A new study found that most medical marijuana users in the US are treating chronic pain, with 85.5% of patients reporting an evidence-based condition. The study analyzed data from states with legalized medical use of marijuana and found a dramatic increase in patient numbers over time.
Cell lines, created from donated tissue samples, require unique considerations when creating research protections due to their value and expertise involved. The new Common Rule may pose unintended consequences for this resource, potentially disrupting scientific progress in cancer research.
Researchers successfully recreated microscopic networks of fibers made of DNA, called NETs, in the laboratory. The study found that these microwebs can capture and kill bacteria, potentially leading to more effective antibiotics and a new approach to treating infections.
A recent study found nearly one-third of women under 40 underwent mammography before breast reduction surgery, despite guidelines recommending against it. The screenings can lead to unnecessary follow-up tests and treatments, wasting time and money.
A new study finds an association between lengthy periods of maternal sleep and late stillbirths, independent of other risk factors. Further research is needed to understand the relationship and its implications for pregnant women.
A new study found that acupressure significantly improved chronic pain, anxiety, depression, and poor sleep in breast cancer survivors experiencing fatigue. Researchers tested two types of acupressure and found relaxing acupressure to be more effective for depressive symptoms and sleep.
A new study found that nearly a quarter of antibiotic prescriptions for children and adults may be unnecessary, with 1 in 7 patients receiving antibiotics for cases that were not medically justified. This highlights the need to reduce antibiotic overuse and its consequences, including contributing to antibiotic-resistant bacteria.
A new survey of first-year internal medicine residents found that those in programs with longer hours, less faculty mentoring, and more research focus had higher depression scores. The study suggests that institutions and residency programs play a critical role in resident mental health.
A new study found that more than half of medical cannabis users drive under the influence within two hours of use, with one in five driving 'very high'. The researchers urge for clearer guidelines and public education to increase awareness of cannabis-related driving impairment.
A partnership between Kellogg Eye Center and the University of Michigan used radio-frequency identification (RFID) to track patient wait times and enhance time spent at the doctor's office. The smart clinic model improved efficiency and boosted transparency, allowing doctors to monitor patients' movements and provide timely reassurance.
A new review by Michigan Medicine researchers shows that opioids are a key contributor to the rise in suicides and drug overdoses in the US. The study calls for improvements in pain care, mental health care, and medication-assisted opioid addiction care to reverse this deadly trend.
A new study finds that genetic testing for breast cancer does not cause excessive anxiety, even with ambiguous results. Researchers surveyed 1,063 women and found that the type of test or result did not significantly impact worry levels.
A new national poll suggests that many people in their 50s and early 60s harbor serious worries about their health insurance status, now and in the future. The poll found that 45% of those age 50-64 concerned they won't be able to afford insurance in retirement.
A genomic duplication in Caucasians could contribute to the high incidence of esophageal adenocarcinoma. Researchers found that African-Americans have a protective genetic variant, GSTT2, which may help prevent cancer. Flavonoids derived from cranberries show promise as a potential chemoprevention agent.
A new study reveals that firearm-related deaths are the second leading cause of death among US children and teens, accounting for over 60% of preventable deaths. The rate of firearm-related death remains persistent, with over eight children dying daily, and disproportionately affects urban adolescents and African-American youth.
A new study published in BMJ found that primary care doctors need to work six more hours a day to provide recommended preventive care, including colonoscopy and lung cancer screening. The simulation model also reveals that this would lead to 17 out of every 100 doctors taking early retirement each year.
A new study finds striking inconsistency in parental leave policies at top residency programs, highlighting the need for balance between medical training and personal/family needs. The average maternity leave was 6.6 weeks, with paid leave policies averaging only 3.9 weeks for same-sex couples or adoptive parents.
Veterans in mental health care support measures to address firearm access, such as screening by clinicians and gun locks. The VA could consider working with veterans to develop and implement these programs to prevent suicide.
A new study found that 14% of people with Type 2 diabetes who don't require insulin test their blood sugar levels two or more times a day, exceeding medical guidelines. This can result in millions of unneeded tests and wasted insurance funds.
A study found 29% of veterans who underwent recommended colonoscopies were uncomfortable with stopping screenings when benefits were expected to be low. Participants preferred a more personalized approach to screening decisions, citing mistrust in life expectancy calculators and age-based guidelines.
A new study by Michigan Medicine found that nearly half of people covered by expanded Medicaid felt their physical health improved, while more than a third reported improvements in mental or dental health. Enrollees who were employed also reported better job performance and had easier times looking for jobs.
A new report highlights the common challenges faced by large health systems when implementing telehealth programs, including engaging leadership, prioritizing areas for support, and educating patients. Despite these hurdles, investing in telehealth can lead to significant cost savings and improved patient access.
Researchers analyzed brain scans from hundreds of people with OCD, finding that brains get stuck in a loop of 'wrongness' and have trouble stopping repetitive behaviors. The study identifies specific brain areas and processes linked to OCD, setting the stage for new therapy targets.
A new study found that amphetamine and opioid use in pregnancy increased substantially over the last decade, particularly in rural counties. Amphetamine-affected births doubled, while the rate of opioid use quadrupled, resulting in higher risks of severe maternal morbidity and mortality.
A survey of 800 adults undergoing bariatric surgery found that patients prioritize expected out-of-pocket costs and weight loss potential. This approach may differ from the procedure's related risks or recovery time. The study suggests healthcare providers should discuss cost with patients to ensure informed decision-making.
Researchers have developed a new method to identify differences between single cells using single nucleotide variants, which can eliminate biases in traditional sequencing methods. This technique uses variant information to retrieve gene expression data, enabling better identification of tumor subpopulations.
A study reveals that current screening tools can miss severe infections in pregnant women, highlighting the need for better identification and timely interventions. Simple measures such as frequent vital sign reassessment and prompt antibiotic administration within an hour of diagnosis can significantly reduce maternal deaths.
A Michigan Medicine study finds that nearly half of suicidal adolescents who watched Netflix's '13 Reasons Why' reported an increased suicide risk, highlighting the need for parental vigilance and tailored prevention programming. The majority of teens who discussed their reactions with peers did so without a parent's involvement.
A new website aims to change the equation on death and trauma from firearms among young people by sharing what's known about guns and people under age 19. The site offers a trove of data and training for health care providers, researchers, and others to tackle the prevention of youth firearm injuries as a public health issue.
Researchers found that using low-cost portable air purifiers at home significantly lowered urban seniors' fine particulate matter exposure and blood pressure. The study showed a 40% reduction in air pollutant exposure and an average of 3.4 mm Hg decrease in systolic blood pressure.
Researchers discovered that mitochondria deploy ROS to destroy invading MRSA bacteria by packaging and delivering these molecules to the phagosome, bypassing traditional immune mechanisms. This backup system helps immune cells fight off pathogens with increased effectiveness.
A new study found that surgery patients often take less than half of the prescribed opioid pain medications, with prescription size being the most important factor. The study suggests that surgeons can reduce opioid prescriptions and improve patient safety by considering individual factors such as pain scores and operation intensity.
A new study finds that hospitals' progress in reducing hospital-acquired pressure ulcers (HAPUs) is largely due to preventing less-costly and less-dangerous early-stage HAPUs. The study recommends better data tracking methods, including using the same approach as for infections, to adjust rates and penalties based on patients' underlyi...