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Penn State


A new class of functional elements in the human genome?

Research finds that unusual DNA structures, called G-quadruplexes (G4s), are preserved by natural selection and play a role in gene expression and cellular processes. G4s are more common and stable in regions with important functions, suggesting they should be considered functional elements of the genome.

SourcePenn State·JournalGenome Research·DateJun 29, 2021

Ethane proxies for methane in oil and gas emissions

A recent study using ethane proxies has found that oil and gas wells contribute significantly to greenhouse warming, exceeding EPA estimates by 48-76%. The researchers tracked ethane and methane emissions across the US over three seasons, providing new insights into fossil fuel sources.

Innovative batteries put flying cars on the horizon

Researchers at Penn State have designed and tested prototype batteries for electric vertical takeoff and landing (eVTOL) vehicles, which require high energy density and rapid charging. The batteries can sustain over 2,000 fast-charges and retain some charge to ensure safety in the air.

SourcePenn State·JournalJoule·DateJun 7, 2021

NSF renews funding for Two-Dimensional Crystal Consortium

The National Science Foundation has renewed funding for the Materials Innovation Platform at Penn State's Materials Research Institute, enabling the development of new ultra-thin materials with unique quantum properties. The facility will advance 2D materials research across the US, supporting over 100 scientists nationwide.

Mapping the local cosmic web

Researchers have created a new map of dark matter in the local universe using machine learning, revealing previously undiscovered filamentary structures connecting galaxies. The map provides a detailed understanding of the distribution of dark matter and its gravitational influence on galaxies.

Global pollen samples reveal vegetation rate of change

Researchers analyzed global pollen data to study the global rate of change in vegetation, finding a worldwide acceleration in compositional change between 4.6 and 2.9 thousand years ago. Human influence on terrestrial ecosystems exceeds climate-driven transformation during this period.

SourcePenn State·JournalScience·DateMay 20, 2021

Few women in sub-Saharan Africa undergo cervical cancer screenings

A recent study found that only 19% of women in sub-Saharan Africa underwent cervical cancer screenings between 2011 and 2018. The rates varied greatly by country, with some countries having nearly 46% of women screened versus less than 1%. Increasing screenings is crucial to detect the disease early and improve treatment outcomes.

SourcePenn State·JournalCancer Epidemiology·DateMay 18, 2021

Linguistic and biological diversity linked

Researchers found that Indigenous languages overlap with 8,200 species ranges in African UNESCO sites, suggesting a strong connection between cultural and biodiversity preservation. The study suggests engaging Indigenous people in governance to redesign management strategies and conserve localities.

SourcePenn State·JournalConservation Biology·DateMay 17, 2021

Maternal stress during pregnancy may shorten lifespans of male lizard offspring

A Penn State-led study found that maternal stress during pregnancy can shorten the telomeres of male lizard offspring, leading to decreased lifespan. The researchers discovered a sex-specific effect, where stressed mothers give birth to sons with significantly shorter telomeres, highlighting potential implications for human longevity.

SourcePenn State·JournalComparative Biochemistry and Physiology·DateMay 14, 2021

Graphene key for novel hardware security

Researchers at Penn State have developed a novel graphene-based physically unclonable function (PUF) that is more energy-efficient and secure against AI attacks than silicon-based devices. The device's unique properties make it resistant to machine learning attacks, adding tamper resistance as another security feature.

SourcePenn State·JournalNature Electronics·DateMay 10, 2021

The legume family tree

A comprehensive study of the legume family reveals a history of whole-genome duplications and helps uncover the evolution of genes involved in nitrogen fixation. The research team identified strong evidence for 28 separate whole-genome duplication events, shedding light on the evolutionary spread and diversification of legumes.

SourcePenn State·JournalMolecular Plant·DateMay 7, 2021

Stop the genetic presses!

Researchers at Penn State discovered a new mechanism for terminating transcription of DNA into RNA in bacteria, facilitated by proteins NusG and NusA. The study found that these proteins together facilitate termination at about 88% of intrinsic terminators, expanding our understanding of gene regulation and potential antibiotic targets.

The micro-environment of breast cancer in three dimensions

Researchers cultivated tumor microenvironments using metastatic triple-negative breast cancer cells and studied the genetic information of entire systems. They found that cellular communication in the microenvironment drives physiological changes in tumor behavior, including growth and movement.

SourcePenn State·JournalAdvanced Biology·DateMay 4, 2021