A Purdue University team, led by Gaurav Chopra and Riyi Shi, received a $1.3 million grant to develop biomarkers and treatments for traumatic brain injury-related Alzheimer's disease and dementia. The researchers aim to improve understanding of microglial cell states in the context of TBI-related neurodegenerative dementia.
Novilytic, a Purdue University-affiliated bio-analytics startup, has received a $1.4 million Phase II SBIR contract to continue developing its Proteometer instrument technology for pharmaceutical antibody manufacturers. The technology allows process chemists and engineers to monitor and control antibody purity in process.
The team's innovation uses acoustic waves to enable faster tuning of components, resulting in higher-resolution lidar detection. The technology integrates microelectromechanical systems (MEMS) transducers made of aluminum nitride to modulate the microcomb at high frequencies.
Researchers have developed a novel immunotherapy using genetically modified natural killer cells to target and kill cancer cells in glioblastoma multiforme, a highly aggressive brain tumor. The treatment approach has shown high efficiency and is considered safer than other cell-based therapies.
SpeechVive, a Purdue University-affiliated medical device company, has secured a convertible note to scale its business and expand access to its wearable device for treating Parkinson's disease. The funding will allow the company to pursue reimbursement from Medicare and commercial insurance companies.
Human monoclonal antibodies isolated from infected children neutralize enterovirus D68 and protect against infection and paralytic disease. The antibodies, which recognize diverse antigenic variants, show high potency and effectiveness in animal models.
Researchers at Purdue University have created a more sustainable and greener method for producing composite boards by utilizing non-food-based biomass such as wood chips or rice straw. The new process reduces the use of formaldehyde-based resin binders, posing significant health hazards in consumer products.
A new study from Purdue University finds that mothers do not have diminished attention and may even have better executive control attention compared to non-mothers. The research used a revised Attention Network Test to compare reaction times among 60 mothers and 70 non-mothers, finding no evidence to support the 'mommy brain' stereotype.
KinaRx aims to create more effective drugs using a novel platform that targets gene mutations driving cancer growth. The company has developed novel RET inhibitors with promising results in preclinical experiments.
Purdue University researchers develop a technique using sunlight to identify satellite issues, potentially reducing the risk of 'space junk'. Light curves collected from satellites or their parts can reveal structural malfunctions.
A novel wearable patch has been developed to deliver chemotherapeutic drugs directly to melanoma sites, providing a more sustainable and long-lasting treatment experience. The patch uses biocompatible silicon nanoneedles that dissolve in tissue fluids, reducing toxicity and side effects associated with conventional treatments.
Six Purdue University researchers received $212,845 from the Trask Innovation Fund to support their patented innovations in life science and physical sciences. The funding will aid faculty and staff with commercialization efforts through the Purdue Research Foundation Office of Technology Commercialization.
The OPTIMUSCLOUD system uses machine learning and data science principles to develop algorithms that optimize virtual machine selection and database management system options. This results in significant cost savings for cloud vendors and clients alike.
Researchers at Purdue University have developed a technique to analyze the energies of 'hot' electrons, which could lead to more efficient energy conversion in solar panels and other applications. The method uses a scanning tunneling microscope integrated with lasers and optical components.
KinaRx LLC, a Purdue University-affiliated startup, has received a $2 million SBIR grant to develop novel kinase inhibitors for treating relapse in acute myeloid leukemia (AML) and other diseases. The company's platform aims to rapidly create complex drug molecules using bioinformatics and multi-component compound synthesis.
The Purdue team's testing showed that SOPHIA achieved significant benefit over default and static-optimized database configurations, with improved throughput across various workload types. The technology was tested on metagenomics, high-performance computing, and IoT workloads, demonstrating its versatility.
Purdue University innovators have developed a predictive cost-modeling tool to help manufacturers better understand overall production costs. The software allows users to vary manufacturing processes and study the effects on total costs.
Gen3Bio Inc., a Purdue University-affiliated startup, has developed proprietary technology to transform waste algae into specialty chemicals. The company has received $20,000 in investments through the Elevate Nexus Regional Pre-Seed competition and a $20,000 pilot plant grant from The Water Council.
A new wearable device aims to prevent SUDEP, a deadly complication of refractory epilepsy. The device monitors key biomarkers and sends alerts to caregivers when abnormalities are detected.
A team of engineers has created hardware that can learn skills using a type of AI that currently runs on software platforms. The hardware, made of a quantum material, is capable of learning numbers and demonstrates artificial tree-like memory at room temperature.
Male treefrogs synchronize their mating calls with neighboring frogs to create an auditory illusion that attracts predators to the leading call, leaving females unaffected. Researchers found this strategy allows male frogs to find mates without risking their lives.
A new patented process using ligand-assisted chromatography enables the efficient and environmentally friendly purification of critical rare earth metals. The technology, developed by Purdue University, has successfully shown to separate the metals without devastating environmental effects.
Purdue researchers develop new technology to overcome resolution limit of light-based microscopy, allowing for high-resolution imaging of biomolecules within cells. This advancement has the potential to reveal structural complexities in neurodegenerative diseases like Alzheimer's, enabling better understanding and treatment.
Researchers at Purdue University are working on a method to fabricate wind turbine substructures and anchors using 3D-printed concrete, which could reduce material costs and increase design flexibility. The team is collaborating with RCAM Technologies to develop concrete additive manufacturing for offshore wind energy technology.
Akanocure Pharmaceuticals Inc. has received a $750,000 Small Business Innovation Research Phase II grant from the National Science Foundation to develop chemical tools and platforms to produce valuable chemical building blocks.
A Purdue University-led research team has found a way to make halide perovskites stable enough for use in solar panels and electronic devices. By inhibiting ion movement, the researchers unlocked their potential to form heterostructures that can perform multiple functions.
Purdue University researchers developed a technique to turn waste polyethylene terephthalate into battery components using ultrafast microwave irradiation. The technology has shown promising results for lithium-ion and sodium-ion battery cells, offering a low-cost and sustainable solution for renewable energy storage.
A new carbon dioxide sensor developed by Purdue University researchers can help manage climate control and indoor air quality, reducing energy consumption. The sensor uses resonant sensing and resistive sensing to detect CO2 levels, allowing heating and ventilation systems to adjust accordingly.
A new study from Purdue University and Stanford University researchers found that football offensive linemen experience at least 40% fewer hits to the head if they start a play standing up. This change could potentially eliminate significant numbers of hits without affecting the game.
A new optical imaging technology developed by Purdue University researchers may improve outcomes for patients with cancer and brain diseases. The technology uses contrast in light absorption to locate tumors and study neuron activation, providing more detailed information than current methods.
Researchers at Purdue University have developed a technique that uses laser-texturing to create nanoscale patterns on metal surfaces, instantly killing bacteria and viruses. The technology has potential applications in medical devices such as orthopedic implants and wearable patches for chronic wounds.
A new startup, Oqullo, is developing a platform that utilizes computer visual algorithms and network cameras to gather demographic information about customers. This data can be used to offer personalized experiences in shopping, traveling, and other consumer activities.
A cloud-based supply chain management system for emergency response has been developed by Purdue University researchers. The system allows for real-time tracking of supplies and aid, enabling better targeting of assistance to those most in need. This innovation aims to improve outcomes for individuals impacted by natural disasters.
The US Navy is funding AnalySwift's SwiftComp software to improve the durability analysis of composite flexbeams in helicopters. This will reduce redesign time and cost, enabling more accurate predictions and saving millions of dollars.
Purdue University scientists are rapidly developing technologies to diagnose and treat COVID-19, including paper-based rapid-detection systems and environmental decontamination methods. Industry partners are being sought to license these innovations and bring them to market.
Researchers have developed new technologies to compress 3D camera files and automate focus and exposure settings, making them easier to use. The innovations enable users to obtain high-quality images with minimal training requirements.
Researchers at Purdue University have developed a device that can detect changes in the extracellular matrix, a structure surrounding cells in the human body, to monitor disease progression. This non-destructive method uses sound waves to measure stiffness, providing an alternative to damaging methods.
Purdue University researchers have created a novel system that allows multiple players to interact with the same VR game on smartphones, reducing latency and improving user experience. The Coterie system enables 4K-resolution VR on commodity mobile devices and supports up to 10 players in the same application.
A new climate change model developed by Purdue University researchers projects a 10%-20% increase in electricity and 2%-5% increase in water demand in the Midwest due to global warming. The model considers multiple climate variables, including temperature, humidity, wind speed, and large-scale phenomena like El Niño.
Purdue University researcher Alexander Chubykin is working on developing new biomarkers to diagnose autism and schizophrenia. He believes understanding how the brain predicts future events can help individuals with these disorders better navigate their environments and manage sensory overload.
Researchers at Purdue University have developed a collapsible basket technology that aims to improve drug discovery and personalized medicine. The technology accelerates the analysis process by reducing the time-consuming step of retrieving cell and tissue samples for histological analysis.
Purdue University researchers have developed a new adhesive system that uses sacrificial bonds to make materials more resistant to stress and cracking. The technique, inspired by nature's adhesives in sea creatures, may be applied to various industries such as electronics, vehicles, and construction.
The Toolkit for Selective Analysis and Reconstruction of Files (FileTSAR) is a comprehensive tool that allows forensic investigators to capture, analyze, and reconstruct files from network traffic. Developed by Purdue University experts, the tool has been licensed to over 100 law enforcement agencies worldwide.
A new technology developed at Purdue University has shown promise in treating obesity and diabetes by converting bad fat into good fat. The Adipo Therapeutics team is seeking additional funding to further develop their technology and submit it to the FDA.
Purdue University researchers have created a novel way of doing some medical imaging using formable and stretchable RF coils. The technology provides an excellent signal-to-noise ratio for enhanced MRI scanning, making it more comfortable and accessible for patients.
Purdue University researchers developed a novel turbomachine expander to harvest wasted energy in vapor-compression heat pump cycles. The device offers more efficient and safer cooling options for companies and vehicles.
A Purdue team has received a $3.2 million grant from the National Institutes of Health to treat antibiotic-resistant lower respiratory infections, a leading cause of death worldwide. The researchers will develop new inhalation therapies using polymyxins and liposomes to combat antimicrobial resistance.
A study found that drinking water quality in homes differs by room and changes with seasons, raising concerns about water safety. Researchers collected data 58 times at a single house over a year, logging 222,000 hours and 2.4 billion records.
Researchers at Purdue University have developed a mixed-signal hardware security solution that thwarts powerful electromagnetic attacks on Internet of Things devices. This breakthrough technology enhances security by 100 times compared to current solutions, making it essential for protecting resource-constrained edge devices.
Researchers developed a pancreatic tumor model that condenses cancer development to just two weeks, allowing them to observe trends in cell growth and invasion. The study found that cancer cells from different mutations become more invasive when they grow together, which challenges the current understanding of disease progression.