Research finds that increased body weight is associated with higher levels of inflammation, signs of gut permeability, and poorer asthma control. The study suggests that targeting the gut could be an effective treatment target for improving asthma control in patients with obesity. Weight loss may also improve symptoms for these patients.
The joint position statement from British Menopause Society, RCOG, and SfE provides evidence-based guidance for healthcare professionals caring for women experiencing menopause. It recommends an individualised approach to care, considering the risks and benefits of therapies as well as lifestyle choices.
A recent study published in the Journal of Endocrinology suggests that lowering blood glucose levels can partially restore reproductive hormone levels and ovulation in female mice with obesity. The study used dapagliflozin, a common type 2 diabetes medication, to treat the mice, resulting in improved fertility outcomes.
The use of dexamethasone has been confirmed as an effective treatment for COVID-19, reducing ICU admissions and deaths by 56%. However, the treatment can increase blood sugar levels in patients with diabetes, highlighting the need for monitoring and potential co-treatments.
Research suggests COVID-19 pandemic has adverse effects on women's menstrual cycles due to stress and sleep disturbance. Women are experiencing increased rates of depression, anxiety, and poor sleep.
A new mobile phone app called GrowthMonitor can accurately measure children's height and detect potential growth disorders, enabling early diagnosis and treatment. The app uses a traffic light system to inform parents of normal, amber, or red growth status, empowering them to take action.
The Society for Endocrinology's annual conference will feature world-leading scientific and clinical research on endocrine clinical practice. The event will showcase the latest innovations in endocrine medicine, including Medal and Award lectures by renowned experts.
A mouse study found that vitamin D deficiency impairs skeletal muscle mitochondrial function, leading to reduced energy production and potentially poor muscle strength. The study suggests that preventing vitamin D deficiency in older adults could help maintain better muscle function and reduce age-related muscle deterioration.
A study published in the Journal of Endocrinology found an association between higher body weight and greater menstrual blood loss, potentially due to delayed womb lining repair. The research used a combined approach of human and mouse studies, suggesting obesity may contribute to heavier periods through increased inflammation.
The Hormones: The Inside Story podcast series explores the facts behind hormones and their impact on daily life, sleep, stress, body fat, fertility, and more. It cuts through myths and misinformation with expert-led science, empowering listeners to make informed decisions about their health.
A larger thigh circumference may be associated with lower blood pressure and a reduced risk of heart disease in people with obesity. Thigh circumference could potentially be used as an indicator for earlier detection and prevention of high blood pressure and related complications.
A high sugar diet during pregnancy can lead to increased progesterone levels and changes in dopamine function, which may affect mother-pup interaction and long-term mental health. The study suggests that limiting added sugars to 5-10% of daily calories may have benefits for metabolic and hormone health.
A study published in Endocrine Connections found that mindfulness-based therapy can lead to greater weight loss and reduced stress in obese children compared to a calorie-restricted diet alone. The therapy was found to counteract the negative effects of anxiety on weight loss.
Recent study suggests a modest association between radioiodine treatment for hyperthyroidism and increased risk of solid cancer, including breast cancer. The Society for Endocrinology and British Thyroid Association advise caution in interpreting the findings and highlight the need for further research.
Daily exercise at moderate intensity may improve appetite and blood glucose regulation by increasing glucagon-like peptide-1 (GLP-1) levels. Moderate-intensity physical activity for just 30 minutes a day, such as brisk walking or gardening, could lower the risk of diabetes in men.
A study published by Professor Henrik Oster suggests that daily stress coupled with a disrupted internal clock increases the risk of developing metabolic disorders such as obesity and type 2 diabetes. This is because environmental stress can affect food intake, promote weight gain, and have long-lasting effects on stress responses.
Researchers identify potential environmental risk factors and new treatment strategies for triple negative breast cancer (TNBC), an aggressive form of breast cancer. The study suggests that exposure to common chemicals may increase the risk of developing TNBC, and highlights the potential for combination therapy as a treatment option.
Researchers found that healthy men taking commonly prescribed doses of glucocorticoids for a short period experienced changes in blood sugar metabolism, associated with an increased risk of developing diabetes. The study highlights the need for medical professionals to consider and monitor potential side effects.
Pregnant women with low vitamin B12 levels experience increased fat production and reduced breakdown, predisposing them to obesity. A recent study found that vitamin B12 deficiency impairs fat cell metabolism, leading to increased inflammation and impaired metabolic function.
A new study reveals that bariatric surgery can lead to successful weight loss and better diabetes control in older adults. After two years, the patients had lost an average of 24% of their body weight and seen a significant reduction in HbA1c levels. The study suggests that age alone should not be considered a contraindication to baria...
Research suggests that impaired liver function during pregnancy can lead to altered gut bacteria composition in children, increasing the risk of obesity. Maintaining a healthy diet and targeting gut microbiome composition with pre-biotics or pro-biotics may help prevent childhood obesity.
Research suggests that restricting food intake can increase motivation to exercise in mice, potentially leading to weight loss and reduced complications like diabetes and heart disease. This could be achieved through better diet control, such as limiting mealtimes or fasting intermittently.
A study published in the Journal of Endocrinology found that high levels of caffeine during pregnancy can lead to lower birth weights, altered growth hormone levels, and impaired liver development. The study suggests that excessive prenatal caffeine consumption may increase the risk of fatty liver disease in adulthood.
A new study suggests that short-term strength training can improve liver health and blood sugar regulation in obese mice. The findings indicate that strength training may be a fast and effective strategy for reducing the risk of diabetes and fatty liver disease in obesity. However, further research is needed to confirm these results.
A new study suggests that regular vitamin B12 screening in metformin-treated type-2 diabetes patients can reduce the risk of irreversible nerve damage. The study found that nearly 70% of patients were not being checked for vitamin B12 levels, despite a link to peripheral nerve damage.
A new study suggests that antioxidants can reduce cognitive impairments caused by low blood sugar in diabetic patients. The research found that stimulating antioxidant defenses with sulforaphane improved cognitive ability in mice, indicating potential benefits for humans.
A new study found that inflammatory skin disorders like psoriasis increase the risk of type-2 diabetes. Improving skin health could be crucial for controlling blood sugar levels and reducing diabetes risk.
Research using young mice suggests that a nutrient-rich diet during early-life stress can improve brain development and function. The study found that micronutrients could help mitigate the negative effects of early-life stress on cognition, suggesting potential benefits for children's learning and memory abilities.
A new study reveals that women can be as resilient to extreme physical activity as men, contrary to previous claims about gender differences. The research found no significant negative health effects in six female participants who completed a transantarctic expedition.
A live debate at the Society for Endocrinology annual conference explores the roles of gut and brain hormones in regulating appetite and metabolism. Experts argue over whether the gut or brain is more important, with implications for treating obesity and diabetes.
Consuming too much vitamin A may decrease bone thickness and increase fracture risk in humans. A recent study found that mice exposed to lower doses of vitamin A equivalent to 4.5-13 times the recommended daily allowance showed significant weakening of bones over a 10-week period.
Research published in Endocrine Connections found that individuals with type-1 diabetes and depression have higher galectin-3 levels, a protein involved in inflammatory immune responses. Elevated galectin-3 levels were also linked to an increased risk of inflammatory disorders such as Alzheimer's disease and cardiovascular disease.
A review suggests that exposure to thyroid-hormone-disrupting toxins in pregnant women and children may lead to increased incidence of brain development disorders. This has significant implications for child health and underscores the need for targeted public health strategies.
Low levels of vitamin D during pregnancy and breastfeeding have been linked to differences in social behavior in children later in life. The study found that rats born to mothers with vitamin D deficiency displayed abnormal social behaviors, altered brain chemistry, and impaired learning and memory.
A common rheumatoid arthritis treatment, lefluonamide, lowered blood glucose levels and reversed insulin resistance in mouse models of type 2 diabetes. The study suggests that this therapy could be repurposed as an effective antidiabetic treatment for patients with both diabetes and rheumatoid arthritis.
Researchers have discovered a link between male sex hormone levels and vitamin D metabolism that may be targeted to treat osteoporosis in men undergoing prostate cancer therapy. Progesterone receptor blockers could enhance the effectiveness of vitamin D supplements, reducing bone fracture risks.
A review of rodent studies found that paracetamol exposure during pregnancy can reduce the number of eggs in female offspring, potentially impairing future fertility. The findings have implications for pregnant women taking pain relief medication.
A recent review found a link between morning sickness, smoking, and healthy pregnancies, suggesting that impaired endokinin activity may be involved in poor placental implantation. Smoking during pregnancy is known to lead to negative outcomes, while morning sickness symptoms may be caused by overspill of endokinin levels in the brain.
A new study found that phenylalanine reduces food intake by affecting the gut and brain, suggesting it may be used to treat or prevent obesity. The amino acid suppressed appetite by releasing hormones in the gut and activating areas of the brain involved in appetite regulation.
A study found that pregnant women exposed to high levels of perchlorate, a common environmental pollutant, had lower levels of thyroxine (T4), a thyroid hormone essential for normal foetal brain development. This suggests that exposure to this chemical may lead to potential neurodevelopmental abnormalities in children.
A study found that women with PCOS are more likely to be diagnosed with mental health disorders, including depression, anxiety, and bipolar disorder. The research also showed that children born to mothers with PCOS are at a higher risk of developing ADHD and autism spectrum disorder.
Patients with severe burns who have higher levels of vitamin D recover more successfully than those with lower levels. Vitamin D supplementation may be a simple treatment to improve wound healing and combat infection.
A study found that kisspeptin enhances male sexual attraction and decreases anxiety in male mice by activating specific neurons in the brain. Activation of these neurons increases social interaction and reduces anxiety, while having no effect on copulatory behavior.
The prevalence of obesity in the UK has almost doubled over two decades, with food taxes being suggested as a measure to correct this trend. However, experts disagree on its effectiveness, with some arguing it is too simplistic and overlooks other factors influencing obesity.
Research suggests that vitamin D levels combined with good sleep quality can effectively manage conditions like arthritis, menstrual cramps, and chronic back pain. This review highlights the potential benefits of vitamin D supplementation in pain management, offering a new approach to alleviate suffering.
A recent study suggests that treating mild hypothyroidism in pregnant women with levothyroxine may lower the risk of low-weight babies and early caesarean sections. However, there was no significant difference in other obstetric outcomes between treated and untreated groups.
Research reveals that individuals with medical conditions causing low oxytocin levels perform poorly on empathy tasks. Oxytocin replacement may improve psychological well-being in those living with low levels.
Researchers find that using kisspeptin instead of hCG during IVF treatment safely matures eggs and reduces the risk of ovarian hyper-stimulation syndrome (OHSS), even in high-risk patients. The average live birth rate was 45% across all doses, rising to 62% for women given the best performing dose.
A preliminary study found that soy protein and isoflavones can slow down bone loss and lower the risk of osteoporosis in early menopause. The study suggests that incorporating soy foods into a diet could be an effective option for improving bone health in women during this period.
A preliminary study suggests that taking vitamin D supplements daily can improve exercise performance by increasing cycling distance and reducing physical exertion signs. The study also found lower blood pressure and cortisol levels in participants, indicating a potential link between vitamin D and cardiovascular health.