A recent study has found that plaques associated with dementia can disrupt the spread of slow waves in the brain during sleep, impairing memory consolidation. Researchers were able to decode this defect at the molecular level and alleviate it with medication, showing potential for a new treatment approach.
A new hydrodynamical simulation of the universe's visible structure, Magneticum Pathfinder, provides unparalleled insights into the cosmic landscape. The simulation covers a vast area of 12.5 billion light years, featuring unprecedented resolution and detail.
Researchers at TUM have identified how small heat shock proteins interact with other proteins in Alzheimer's disease. They found that these proteins can bind to both amorphous and amyloid forms of beta-amyloid, preventing clumping and potentially developing new agents.
A new concept correlates geometric and adsorption properties in catalyst design. Researchers developed a platinum-based catalyst for fuel cell applications, showing up to three and a half times greater catalytic activity than existing ones.
The UR:BAN project is working on making traffic safer and more efficient by integrating cognitive assistance, connected traffic systems, and human factors. The researchers are also studying bicyclists' tactical behavior and developing information systems to present data to drivers.
A team of researchers at Technical University of Munich has found a way to repair defective mucins, which are key components of mucus. The repair mechanism involves replacing lost sugars with synthetic molecules, restoring the mucins' lubricative ability and paving the way for new treatment strategies.
Researchers have discovered a new molecular marker for killer cells, allowing for the prediction of infection course. The marker, CX3CR1 receptor, is associated with chronic infections, where immune system effectiveness is compromised.
A recent study published in Nature found that broadleaf tree species in Central Europe have shown a significant decline in their sensitivity to climate change. Leaf unfolding phenology, which is the timing of when leaves unfurl in spring, has advanced earlier by four days per degree Celsius increase in temperature between 1980 and 1994...
Researchers designed molecules that suppress protein aggregation, a process damaging cells in Alzheimer's and type 2 diabetes. The findings reveal a novel class of peptide leads that could pave the way for new treatments.
Researchers at TUM and Georgetown University have discovered a common gatekeeping system for tinnitus and chronic pain, which may play a central role in the development of both conditions. The study found significant loss of gray matter and compromised circuit function in regions important for emotional experiences.
A team of international researchers has developed recommendations to preserve the local environment in China's Xinjiang region, which produces ten percent of global cotton production. Sustainable land use practices and reforestation are key to reducing soil salination and preserving groundwater supplies.
Researchers have expanded their search radius for dark matter particles using the CRESST experiment, which can now detect particles with masses below 10 GeV/c^2, including those comparable to a proton. The new detectors are being equipped and will begin measuring in late 2015.
Researchers at the Large Hadron Collider investigate the properties of particles and their antiparticles to understand the universe's matter-antimatter asymmetry. The ALICE experiment confirms the CPT theorem with the most accurate measurements to date.
A new study by TUM scientists links climate change to declining crop yields and humus stocks in arable soils. The researchers found that the stagnation in yields coincides with a decline in organic matter input into the soil, leading to a depletion of humus.
Actin filaments exhibit complex behaviors, including self-organization and active motion. New research reveals that molecular motors play a crucial role in forming strong bends and enabling collective motions.
Researchers at Technical University of Munich discovered that brassinosteroids are necessary for the production of gibberellins, a hormone that regulates cell elongation and division in plants. This finding has important implications for crop breeding and plant growth.
Researchers have developed black arsenic phosphorus as an alternative to graphene for electronic devices. The new material exhibits an extremely small band gap and can be precisely controlled by adjusting the arsenic concentration, making it suitable for sensors and other applications.
A team of researchers has discovered a link between acute liver failure and mutations in the NBAS gene, which affects cellular transport processes. The study found that these mutations can disrupt protein packing and transport within cells, leading to metabolic imbalances in the liver.
A new bio-inspired zeolite catalyst converts methane to methanol with high efficiency and selectivity, enabling small-scale 'gas-to-liquid' technologies. The catalyst's trinuclear copper-oxo-cluster active center is stabilized in the zeolite micropores.
A global strategy for preventative water sample analysis has been developed, utilizing a comprehensive database of 8,000 substances. This allows laboratories to identify previously unknown molecules faster through non-target screening technology, enabling quicker response to potential waterborne risks.
A recent study by Technical University of Munich found that ragweed pollen triggers a strong allergic response due to the presence of adenosine. The protein Amb a 1 alone did not induce such a reaction, but combining it with adenosine led to increased inflammation in lung tissue.
Researchers at TUM have successfully improved the electrical properties of printed films by optimizing the printing process, resulting in custom organic electronics. The team used X-ray radiation to study the curing process and achieved high time resolution, leading to significant improvements in stability and conductivity.
Scientists at TUM have characterized a small heat shock protein essential for embryonic development in nematodes, which may have implications for human health. The Sip1 protein regulates itself via pH value and prevents clotting of important proteins.
A team developed a graphical representation of nuclear spin matrices for coupled spins in arbitrary quantum states, enabling better control and utilization of quantum phenomena. The 'SpinDrops' app provides intuitive access to the fascinating world of quantum control theory.
Doctors at TUM used navigated transcranial magnetic stimulation to map motor areas in patients with malignant brain tumors. This method improved prognosis by reducing residual tumor tissue and shortening hospitalization periods. Mapping of motor areas also enabled surgeons to remove tumors without affecting functional areas.
Researchers at TUM developed a new combination of 3-D printed microfiber scaffolding and hydrogels to restore cartilage, showing elasticity and stiffness comparable to knee-joint tissue. The approach also has potential applications in breast reconstruction and heart tissue engineering.
Researchers at Technical University of Munich develop record-breaking magnetic shielding to dampen low frequency magnetic fields, creating the weakest magnetic field in the solar system. This breakthrough enables high-precision experiments, such as measuring the electric dipole moment of neutrons.
Researchers developed a compact synchrotron source that measures X-ray absorption, phase shifts, and scattering, allowing for the differentiation of healthy tissue from tumors. The new technology has improved soft tissue contrast, enabling quicker diagnoses in medical emergencies.
Researchers investigated wood supply and demand in Bavaria by 2035, finding that using wood as a building material first reduces ecological benefits. Wood scarcity could lead to increased imports and substitute products, affecting jobs and carbon balance.
Researchers at TUM and IME identified a protein complex on rubber particles responsible for the formation of polyisoprene, the main component of rubber. The study found two key proteins necessary for natural rubber biosynthesis in dandelion plants. This discovery brings biotechnological manufacturing of rubber closer.
A study reveals that an unfavorable bacterial network configuration in the gut can cause inflammation similar to Crohn's disease. Researchers found that transplanting 'healthy' bacteria into patients' intestines may provide a conventional treatment option.
The Visio.M project creates a subjectively pleasant climate for passengers in the most energy-efficient manner. The system uses Peltier elements to heat or cool seats directly, reducing waste heat and improving comfort.
Researchers have developed a mass spectrometry-based process to detect the toxic bacteria's emetic toxin, cereulide. The new method identified 18 variants of cereulide and is being evaluated for its reliability in detecting contaminated products.
Researchers at TUM have developed a new approach to joining modular 3D building units using shape complementarity, enabling practical nanomachines with moving parts. This breakthrough offers a toolkit for easy programming of self-assembly, paving the way for applications in DNA origami.
Researchers at Technical University of Munich develop methodology to speed up simulations of complex fluids, enabling more realistic medical diagnoses and spectacular effects in computer games. The approach leverages real-world observations to calculate fluid behavior, promising to accelerate calculations and improve various applications.
Scientists at TUM discovered that brain activity changes when transitioning from sensory to emotional processing during prolonged pain. The experiment showed that nerve cells in the brain trigger a different pattern of activity after applying a placebo cream, reducing perceived pain.
The Visio.M Automotive Service Bus, developed at Technical University of Munich, enables cars to communicate via the internet and drive remotely or autonomously. The system is protected from external attacks and features a uniform user interface with driver-friendly swipe gestures.
The Grete Lundbeck European Brain Research Foundation has awarded TUM Prof. Arthur Konnerth the million-euro Brain Prize for his work on two-photon microscopy, enabling detailed images of individual nerve cells and synapses in living brains. His research has improved understanding of brain development, plasticity, and functional circui...
Physicists at TUM and University of Cologne develop theoretical description of behavior for magnetic vortices in conductors, semiconductors, and insulators. The theory predicts properties for optimal device development, promising compact frequency devices with high efficiency.
Researchers discovered a plant immunosensor that detects lipopolysaccharide, a substance occurring in pathogenic bacteria. The LipoOligosaccharide-specific Reduced Elicitation (LORE) protein initiates an immune response in plants, similar to the toll-like receptor 4 in mammals.
Scientists have identified Interleukin 4 (IL-4) as a promising treatment for psoriasis, a chronic autoimmune disease. By inhibiting specific immune cells, IL-4 reduces inflammation and improves skin conditions in patients.
Scientists from TUM and LIU create technology to cage molecules in 2D nanopores, allowing them to investigate thermal behavior of individual species. They successfully track molecule motions at sub-nanometer resolution using scanning tunneling microscopy.
Researchers at TUM create self-assembled catalyst to facilitate terpene cyclization, enabling production of complex compounds like taxol, used in cancer treatment. The breakthrough yields higher yields and improves reaction feasibility.
A survey by TUM found that two-thirds of Germans support democratic management, with employees seeking more autonomy in work life. However, managers believe implementing such systems is challenging.
A new study confirms dark matter's presence in the inner part of the Milky Way, including at our own cosmic neighborhood. Scientists created a comprehensive compilation of published measurements to observe rotation speeds and found that dark matter is needed to explain observed speeds.
Electrons in a crystal lattice move at incredible speeds, with one type of electron traveling at 5000 km/s. By studying the delay between electrons traveling through different atomic layers, researchers gained insight into the behavior of electrons within the crystal's microcosm.
Scientists discovered that Tregs need continuous contact with their environment to function correctly and require the T cell receptor for protection. The study showed that Tregs without the receptor lose their special ability to suppress excessive immune reactions.
Researchers found a mutated region in human mantle cell lymphoma DNA that disables programmed cell death. Cells with this mutation grow uncontrollably, but a new therapy approach targets the ubiquitin ligase responsible for the defect.
Researchers at the Technical University of Munich have discovered that broccoli's sulforaphane can reduce progerin accumulation and DNA damage in HGPS cells. The study suggests that this natural compound could be a potential therapeutic approach for treating the disease.
A research team from TUM discovered that birds use their oval-shaped heads to transform sound waves, allowing them to identify sounds from different elevation angles. This unique ability combines information from hearing and vision to improve orientation and evading predators.