A team of researchers at the Technical University of Munich has identified a receptor that limits the immune response to uric acid crystals, preventing overreaction and damaging healthy tissue. The discovery sheds light on the fundamental mechanism by which the immune system recognizes crystalline structures.
Researchers at TUM have found that the heat shock protein Hsp90 binds to prefolded tau proteins, which are characteristic of Alzheimer's disease. This discovery provides important insights into the mechanisms underlying the disease and may lead to new therapies.
Scientists create a cost-efficient way to set up thousands of experiments simultaneously using tiny droplets. Their experiment shows that oscillations in the individual droplets differ strongly, with small drops displaying stronger variations than large ones.
Researchers at TUM have developed two new mechanisms of action that can permanently deactivate ClpP proteases, essential for bacterial survival. The newly discovered inhibitors target the protein's structure and function, potentially leading to more effective treatment options.
The symposium highlights two promising lines of research: unlocking natural diversity in maize genomes to secure global food supplies, and applying nanotechnology to improve renewable energy efficiency. Researchers from TUM and international partners present recent advances in these fields.
Scientists have created a new statistical method to analyze individual cells, allowing for more accurate detection of cell properties. By combining data from multiple cells, researchers can reduce errors and overcome statistical noise, leading to better understanding of cellular behavior and development.
Researchers at TUM developed a system that uses cell phones as transponders to measure distance accuracy of a few centimeters within microseconds, enhancing safety and movement prediction. The technology can also identify vulnerable road users like pedestrians and cyclists even behind obstacles.
A team at TUM has developed a glass-based detector that accurately determines the form of light waves in individual femtosecond pulses. The new detector simplifies measurements of ultrafast physical processes and enables the generation of stable attosecond light flashes with controlled shape.
Researchers discovered a mutation in the TMEM95 gene causes idiopathic male subfertility in cattle. The study found that genetic defects can be traced back to one Fleckvieh animal born in 1966, which also highlights potential human medicine applications.
Researchers at TUM discovered that carbon binds to small mineral particles with rough surfaces, leading to preferential spots for sequestration. The study used a mass spectrometer to visualize and compare soil structures, revealing areas with high carbon content.
Scientists at Technical University of Munich have discovered a way to create natural substances using photoreactions and a special catalyst, reducing the formation of unwanted mirror-image variants. This method has potential for industrial applications in drug development and plant protection.
Researchers create professional development program to foster classroom dialogue, leading to increased student interest and motivation. The program involves video recordings of seminars and class time analysis, promoting a relaxed control environment and individual attention.
Scientists have demonstrated laser action in semiconductor nanowires that emit light at technologically useful wavelengths and operate at room temperature. The nanowire lasers could represent the next step in developing smaller, faster, more energy-efficient sources of light for various applications.
Researchers at TUM developed a computer model of acoustic coding in the inner ear and neuronal information processing by the brain stem, allowing for improved coding strategies and faster testing of new devices. This advancement has the potential to significantly reduce development cycles and provide better hearing outcomes for patients.
Researchers at TUM have devised a scheme that wrings provably strong security out of the physical layer, preventing eavesdroppers from receiving transmitted information. The approach uses two useless frequency bands to 'super-activate' the system and achieve positive capacity for secure communication.
TUM CREATE's electric taxi EVA is designed to address the challenges of limited range and long recharge times in tropical cities. The vehicle features a super-fast charging system that can recharge in just 15 minutes, making it an industry benchmark.
The IceCube experiment has observed high-energy neutrinos from outside our solar system, hinting at the existence of cosmic accelerators. These astrophysical neutrinos may originate from supernovas, black holes, or pulsars.
Research reveals warmer winters allow native plants to grow earlier, but at the expense of native trees and their need for cold sleep. Invasive species, such as shrubs and certain tree species from warmer climate zones, take advantage of this altered timing to start growing earlier and thrive.
Researchers have discovered how αA-crystallin and αB-crystallin proteins prevent protein clumping in the ocular lens, paving the way for new treatment approaches. The molecular switch mechanism triggers protein activation when cells are stressed, such as under heat or stress.
Researchers found that unconscious motivation can influence willpower, with strong power and achievement motivations leading to better performance. The study suggests increasing internal motivation through targeted incentives can help employees overcome challenges with less energy.
Research reveals lithium's unique mode of action in treating depression and bipolar disorders. Lithium accumulation in white matter suggests a new target for psychotropic drugs.
Researchers at TUM have developed a new family of electronic devices using carbon nanotubes, enabling rapid gas detection and low power consumption. These sensors can be integrated into food packaging to gauge freshness or built into electronic skin for robotic applications.
The round goby's rapid colonization of the upper Danube has led to a decline in native fish species such as barbel and European chub. The species' adaptability and dominance of food webs have resulted in a 'novel ecosystem,' with previously unknown combinations of species.
A new type of organocatalyst, using halogen bridges, is introduced as a potentially environmentally friendlier alternative to existing catalysts. This catalyst shows special properties that open up new avenues for application in organic reactions.
Researchers investigate protein diversity, finding that many small changes have no impact, but some can significantly affect functionality. The study suggests that the wide functional spectrum of proteins plays a key role in evolution, and may hold the key to personalized medicine.
A new software solution developed by TUM's Prof. Gritzmann and his team consolidates agricultural land more efficiently than ever before, saving farmers up to 30% on running costs. The algorithm uses sophisticated mathematical ideas to optimize field allocation and reduce travel costs.
Scientists at Technical University of Munich have successfully created 2D patterns using molecules, which could lead to novel physics and chemistry. The patterns, known as snub square tilings, were produced through self-assembly protocols and feature five-vertex connecting elements less than one nanometer across.
The study identifies over 10,000 different proteins in cancer cells, with more than 5,000 present in varying abundance across all types of tissue. The researchers found that the protein pattern determines the effectiveness of cancer drugs, providing new insights into personalized medicine.
Researchers at TUM developed a new method to monitor large plant populations in lakes using aerial images. They created a digital library of plant spectral characteristics to evaluate the images, factoring out image errors and providing early detection of ecosystem risks.
A team of engineers at the Technical University of Munich has successfully demonstrated remote control driving on public roads using Visio.M e-mobility project technology. The system uses video cameras, computer encoding, and LTE connectivity to transmit images, sound, and control data between the driver and the vehicle.
A multicenter study found that whole-body CT scans significantly lower mortality rates for severely injured patients in shock. The comprehensive knowledge gained from the scan enables targeted life-saving emergency treatment, leading to a 25% increased chance of survival.
Researchers have developed an assay to quantify structural avidity in living T cells, a key predictor of success in adoptive transfer therapies. The technology offers advantages over previous methods, including simplicity, non-invasive measurement, and quantitative assessment of binding strength.
Researchers developed a control concept that reduces travel time by about a minute and waiting time by up to seven seconds, increasing intersections that can be passed without stops from 60% to almost 100%. A driver information system was also created to provide speed recommendations to vehicles, resulting in improved traffic flow.
The simTD system uses radio technology to enable vehicles to share information about traffic situations, road conditions, and external factors. This allows drivers to react faster and make informed decisions, resulting in enhanced safety, efficiency, and comfort on the roads.
The new ProteomicsDB contains over 11,000 datasets from human cancer cell lines and tissues, enabling real-time analysis of large data sets. The database provides instant value for researchers to test analytical hypotheses and develop new drugs with reduced side effects.
Scientists at TUM have synthesized a novel framework structure consisting of boron and silicon, which could serve as an electrode material. The LiBSi2 framework has channels that allow for the storage and release of lithium atoms, making it a promising alternative to pure silicon.
A study by TUM found that cheerful women are perceived as less willing to lead, while pride is positively associated with leadership qualities. Researchers hope to develop training programs to challenge stereotypes and assess men and women beyond limitations.
Researchers at TUM developed a new laser technology that produces compact, efficient ultrashort pulses. The technology uses a 'rainbow' buffer to reshape continuous wave output into short intense pulses, enabling applications in biomedical imaging, material processing, and communications.
Scientists at TUM have found that magnetic monopoles can erase data in magnetic vortices, called skyrmions. This discovery has the potential to create extremely compact and long-lived storage media with significantly reduced power consumption.
Researchers at TUM discovered that auxin hormone plays a crucial role in plant growth towards light. By understanding the auxin transport mechanism, they were able to prove its involvement in phototropism for the first time. The study highlights the importance of auxin in regulating plant cell elongation and responding to light signals.
Researchers at Technical University of Munich discover 'desorption stick', a new type of friction that occurs when polymer molecules interact with surfaces. This mechanism depends on the chemical nature of the surface and solvent, not on movement speed or adhesive strength.
Researchers at TUM discovered a new compound responsible for strawberry aroma, involving a previously unknown biocatalytic process. The study reveals the biochemical pathways that produce this flavor compound, which could lead to new applications in industrial biotechnology.
A study by Technische Universität München found that entrepreneurs who prioritize their business goals over environmental concerns do so unconsciously, despite having strong values. Entrepreneurs with high self-efficacy and a challenging business climate were more likely to disengage from pro-environmental values.
Researchers found Fe-60 iron atoms in sediments from ocean cores dating back to 2.2 million years ago, indicating a possible supernova impact on Earth. The discovery suggests that magnetotactic bacteria may have created magnetite crystals containing the radioactive isotope.
Researchers discovered that brain's 'slow waves' start in the cerebral cortex and are initiated by a local cluster of neurons. This finding provides new insights into processes like memory consolidation and learning, and could lead to a better understanding of diseases like Alzheimer's.
The VOI is a compact, two-wheeler electric scooter designed to transport passengers safely and comfortably through congested city streets. Its modular design allows for various configurations, including cargo boxes and mobile kitchens.
Scientists have developed a new method to create genetically modified mice that accelerates the process by four months, using TALEN enzymes. This technique allows for the efficient production of mouse models for diseases like dementia, reducing the need for numerous test animals.
Physicists at Technical University of Munich develop a method to store information in mechanical vibrations, reducing sensitivity to electrical interference. This innovation could lead to more powerful quantum computers by utilizing carbon nanotubes as quantum bits.
Scientists chart individual T cells' fates to better understand immune response modeling and manipulation. They found that a sample of at least 50 individual cells is needed to generate a predictable immune response.
Researchers at Technical University of Munich created a numerical model to study complex fluids, such as ketchup, which exhibits unusual behavior when shaken. The model explains the effects of long-chained polymer molecules on flow resistance, providing new insights into the microscopic mechanisms driving these phenomena.