A team of scientists developed a new approach to visualize oxygen in tissue, using optoacoustic methods and a novel algorithm that corrects for light propagation effects. This non-invasive imaging method achieves high accuracy and resolution, enabling the study of various medical conditions such as tumor growth and metabolism.
Researchers at TUM developed a new mortar resistant to water uptake by adding a biofilm produced by the bacterium Bacillus subtilis. The hybrid mortar exhibits a high contact angle, similar to Teflon, reducing the likelihood of liquid absorption.
A team of researchers from TUM has identified a molecular signaling pathway for programmed cell death that is suppressed in leukemia cells. This discovery offers new insights into the mechanisms underlying cancer progression and may lead to targeted treatment options.
Scientists at TUM develop a methodology to produce 2D quasicrystals from metal-organic networks, opening the door to new materials. They discovered a new set of building blocks for assembling various quasicrystalline structures.
Scientists at TUM have discovered a plant-inherent water-conservation strategy that enables plants to absorb carbon dioxide while minimizing water loss. By activating this mode, plants can preserve moisture in the ground for later use during droughts, potentially increasing crop yields with limited water availability.
Researchers at TUM developed a new molecular method to investigate the function of thousands of proteins in parallel. They identified hundreds of previously unknown interactions among proteins using DNA-printed protein arrays, which enabled them to study protein functions more efficiently. The new method has the potential to accelerate...
Researchers at Technical University of Munich develop a helmet-mounted display that combines terrain information with sensor readings to enhance helicopter flight in poor weather conditions. The technology improves pilot performance and reduces stress symptoms.
A long-term study in over 200 pregnant women found that a special diet rich in omega-3 fatty acids did not result in children being slimmer or fatter than those from the control group. The study challenges earlier findings that suggested omega-6 fatty acids might contribute to infant obesity.
A recent study published in BMC Genomics has identified a gene mutation responsible for high juvenile mortality in calves. The mutation affects the structure of cilia in airways, leading to chronic infections and respiratory disease.
The Bavarian Alps have seen a 14% decline in topsoil organic matter over the past three decades, primarily caused by climate warming. Implementing humus-promoting forest management can help mitigate floods and preserve soil fertility, water balance, and nutrient supply.
Scientists identified four new risk genes linked to epigenetic mechanisms in MS, which affect gene regulation within immune cells. These findings suggest that environmental influences play a significant role in the development of MS, with epigenetic signals marking DNA sequences and regulating gene activation.
Researchers at TUM identified the molecular mechanism of thalidomide, revealing a common link between its teratogenic and anti-cancer effects. The study found that disrupting the protein complex CD147-MCT1 leads to both developmental defects and tumor cell death.
Researchers found that diverse land use can balance out uncertainties and provide optimal multitasking for ecosystem services. The area mosaic concept resulted in 46% forestry utilization with indigenous alders and exotic pines, balancing out 10% extensive pasture and 20% intensive pasture utilization.
A diet lacking in zinc is detrimental to human and animal health due to impaired digestion. Even slight zinc deficiency impairs pancreatic digestive activity and results in significant digestive impairment at an early stage.
Scientists at Technical University of Munich have developed a biochemical strategy to synthesize natural and artificial medical agents using templated enzyme design. They successfully produced precursor of Taxol, anti-inflammatory substances, and omega-3 fatty acids, showcasing the potential of their new molecular toolkit.
Researchers at TUM and MPI have developed a method to identify active regulatory DNA regions controlling genes. This breakthrough enables scientists to study how genes are controlled in different cell types, shedding light on gene regulation and its role in diseases.
A clinical study confirmed a strong correlation between minor heart rate irregularities and the survival prospects of heart attack patients. The new method, measuring respiratory sinus arrhythmia, produces a specific picture of the body's functional condition.
The Werner Siemens Foundation has donated 11.5 million euros to support the launch of Synthetic Biotechnology at the Technical University of Munich (TUM). This new focus integrates research approaches from biochemistry, bioinformatics, and industrial biotechnology.
A new study by TUM researchers has identified singlet oxygen as a potential culprit behind the short battery life of lithium air batteries. The highly reactive substance is created when the batteries are charged, corroding surrounding material and decomposing electrolytic fluid.
Researchers developed a synthetic cell model to investigate fundamental principles of cellular mechanics, revealing the interplay between cytoskeleton and cell membrane is key to changes in form. The model cells demonstrate that protein interactions are essential for biological functions and can alter shape through deformation mechanisms.
Researchers at TUM and USA colleagues have discovered unusually high concentrations of radioactive 60Fe in lunar samples from Apollo missions 12, 15 and 16. This evidence supports a supernova hypothesis, suggesting that one or more explosive events occurred close to our solar system approximately two million years ago.
A study of 200 years reveals a steady loss of butterfly species in nature conservation areas, which are largely ineffective in protecting them. The decline is attributed to high emissions of reactive nitrogen, promoting the growth of plants that outcompete larval host plants and alter nutrient composition.
Geophysicists use GOCE data to visualize the Earth's crust beneath, shedding new light on plate tectonics and geological characteristics. The technique, developed by TUM researchers, enables three-dimensional imaging of the Earth using two grids – similar to stereoscopic vision with two eyes.
A groundbreaking study led by Dr. Dagmar Krüger has revealed that the human gut's secretory capacity does not decline with age, contradicting long-held assumptions. The research team examined over 2200 specimens from 450 patients with bowel disease and found no correlation between intestinal secretion and age or gender.
Researchers find that companies with women on their boards are valued more highly by stock markets, but only because the best women have worked harder to get there. The study suggests that firms should apply equal standards for both men and women to select board members.
Researchers discovered a mutated ANGPTL4 gene that lowers triglyceride values in the blood, reducing the risk of coronary disease. This breakthrough may lead to new medications that simulate the effect of this mutation, providing a concrete goal for future research.
Scientists at TUM create two new nanoscale machines with moving parts using DNA origami techniques, pushing the limits of programmable, self-assembling construction material. The rotor mechanism can swing freely or dwell in specified positions, while a hinged machine demonstrates precise placement of individual molecules.
Scientists at TUM have engineered ordered monolayers of molecular networks with photovoltaic responses, utilizing self-assembly on atomically flat, transparent substrates. The findings open up possibilities for the bottom-up fabrication of optoelectronic devices with molecular precision.
Researchers at Technical University of Munich developed an universal mathematical model that describes how sound waves propagate through the internally coupled ears and which clues for localizing sound sources are created. This system enables animals to pinpoint sound sources, a mechanism applicable to over 15,000 species.
A study published in Gut journal found that oral and intravenous iron replacement therapies alter the gut microbiota significantly, particularly in Crohn's disease patients. These changes may lead to unstable bacterial ecosystems and increased risk of disease flares.
Recent advances in T cell therapy have brought the idea of fighting chronic infections and cancers closer to reality. The use of potent cells with a safety mechanism has been demonstrated, and clinical trials have yielded highly promising results.
TUM researchers are developing self-healing materials to repair cracks in concrete structures. They use bacteria, hydrogels, and epoxy resin to create a material that can close cracks and prevent water damage. The technology has shown promising results in laboratory tests and is being further developed for use in real-world applications.
A six-year study of over 2,600 species revealed that temporal fluctuations across species are more important than diversity for maintaining ecosystem stability. Asynchronous species development strengthens the interplay between animals and plants.
Physicists at TUM have developed a nanolaser that can be integrated onto a silicon chip, paving the way for fast and efficient data processing with light. The technology has the potential to break barriers of current electronics.
Researchers at TUM and Georgia Institute of Technology found that the size of platinum catalyst particles significantly affects reactivity, with clusters having fewer atoms showing lower activity. The discovery could lead to more efficient production of margarine and other chemicals, as well as new materials.
The thalamus enhances and stores sensory information, allowing the brain to filter out important data and forward it in an amplified form. Researchers have identified the higher-order thalamus as a key player in this process, which has implications for understanding sensory perception and behavior.
The first comprehensive survey on freshwater mussel species in Europe reveals declining stock sizes and habitat degradation. Mussels play a crucial role in aquatic ecosystems, filtering water and maintaining ecosystem balance.
Researchers have observed molecular processes in real-time using X-rays, gaining insights into the printing process. This understanding can help control the arrangement of materials, improving the efficiency of organic solar cells.
Researchers found that patients with IBS have reduced sensitivity in their gut nerves, contradicting previous theories of over-sensitivity. This desensitization could be a protective measure to prevent overstimulation.
Researchers at Technical University of Munich create a highly active molecule that selectively targets the alphaVbeta6 integrin, a common marker in many types of cancer. This breakthrough could lead to patient-specific diagnoses and targeted therapies with minimal side effects.
The TUM team developed the RateX method, which overcomes two serious challenges in information theory by bringing together three essential functions. Their approach could enhance flexibility and reduce costs in various communication systems, including wireless, wireline, optical fiber, and satellite systems.
Researchers at TUM developed a new method to produce extremely thin and robust, yet highly porous semiconductor layers using nanostructured germanium. These layers can be custom tailored with organic polymers to create hybrid materials suitable for small solar cells or batteries.
Researchers at TUM and Los Alamos National Laboratory have discovered a way to prevent the loss of stored quantum information by applying an external magnetic field. The new nanostructures use common semiconductor materials compatible with standard manufacturing processes.
Scientists have unraveled the abilities of multinucleated giant cells, which help the body deal with bulky items that obstruct physiological processes. The treatment for systemic amyloidosis has been found to be effective due to the complement system's role in marking and destroying protein deposits.
Researchers found that pesticides can have lasting impacts on aquatic ecosystems, affecting populations of small crustaceans and zooplankton. The study's results suggest that standard toxicity tests may not capture the full extent of pollution in waters.
Researchers have developed a new computed tomography method that uses scattering to visualize nanostructures in objects measuring just a few millimeters. This technique allows for the precise three-dimensional visualization of collagen fibers in human teeth, revealing their detailed structure for the first time.
Researchers from TUM developed a robust intestinal model for molecular research into incretin release, growing mini-intestines in a test tube that exhibit functions of the human intestine. The mini-intestines can absorb nutrients and release hormones, transmitting signals to control these processes.
Researchers at Technical University of Munich identify key mechanisms behind lithium ion battery capacity loss due to aging. The study reveals that a pacifying layer on the anode consumes active lithium and protects the electrolyte from decomposition.
Researchers at TUM discovered that blood stem cells renew themselves through interaction with surrounding tissue cells, which influences the microenvironment. This feedback loop is essential for maintaining stem cell pool replenishment and has implications for treating leukemia.
Researchers discovered a molecular mechanism that triggers early flowering in thale cress under cool temperatures, allowing for accurate prediction and future modification of plant flowering behavior. This study provides insights into the impact of climate change on plant ecology and has potential applications for crop breeding.