Add BrightSurf on Google Email

The Hebrew University of Jerusalem


Major breakthrough in understanding Prader-Willi Syndrome, a parental imprinting disorder

Scientists at the Hebrew University of Jerusalem have reported a major breakthrough in understanding the molecular basis for Prader-Willi syndrome (PWS), a disease that involves defects in parental imprinting. The researchers created a model for PWS by reprogramming skin cells from patients into embryonic-like cells, showing that pater...

SourceThe Hebrew University of Jerusalem·JournalNature Genetics·DateMay 12, 2014

Neurotransmitters resarch can promote better drugs for brain disorders

Researchers at Hebrew University deciphered the mode by which neurotransmitter inhibitors work, raising hopes for new and effective drugs for brain disorders. The study used baker's yeast as a model and identified flexible domains in the structure of the vesicular monoamine transporter (VMAT) responsible for tetrabenazine binding.

SourceThe Hebrew University of Jerusalem·JournalJournal of Biological Chemistry·DateJan 7, 2014

New compound for slowing the aging process can lead to novel treatments for brain diseases

Researchers at the Hebrew University of Jerusalem discovered a new compound, NT219, that selectively inhibits the aging process to protect the brain from neurodegenerative diseases. The compound's inhibition of IGF1 signaling pathway has therapeutic potential for treating neurodegenerative disorders like Alzheimer's and Parkinson's.

SourceThe Hebrew University of Jerusalem·JournalAging Cell·DateDec 3, 2013

Not just cars, but living organisms need antifreeze to survive

Researchers have discovered that antifreeze proteins in plants and animals prevent frost damage by coating and protecting ice crystals. The study, published in PNAS, used microfluidic devices to observe the binding of AFPs to ice, revealing a strong and irreversible interaction that prevents ice growth even without protein presence.

SourceThe Hebrew University of Jerusalem·JournalProceedings of the National Academy of Sciences·DateFeb 18, 2013