Researchers at Hebrew University of Jerusalem have identified two inclusion bodies, JUNQ and IPOD, with opposing effects on protein aggregation. Aggregation in JUNQ can lead to toxicity, while aggregation in IPOD is protective, suggesting a new potential strategy for designing therapeutics for neurodegenerative diseases.
Hebrew University researchers discovered how Plasmodium falciparum hides its genes from the immune system by using an insulator-like DNA sequence. This breakthrough could lead to strategies to disrupt this ability and prevent malaria deaths, mainly among pregnant women and children.
Study finds that people can't accurately judge emotions from facial expressions alone but can recognize them through body language. The researchers tested this with dozens of real-life intense images and found that participants were unable to tell apart positive and negative faces.
Researchers at Hebrew University have found that people can read and solve complex mathematical problems without being consciously aware of them. Using a technique called Continuous Flash Suppression (CFS), the team showed that participants could complete arithmetic tasks more quickly when they were unconsciously presented with equations.
Researchers found that limiting carbohydrates to dinner reduced hunger scores, improved anthropometric outcomes, and lowered inflammatory markers in obese individuals. The innovative dietary pattern led to changes in hormonal secretion patterns favoring satiety and reducing metabolic risks.
Researchers found that a timed high-fat diet reduces body weight and alters metabolism to utilize ingested fats for energy between meals. The study suggests scheduling food consumption can be a therapeutic tool to prevent obesity in humans.
A newly discovered neural pathway in the autonomic nervous system reaches bones and regulates bone density during adolescence, affecting fracture resistance throughout life. The finding could lead to new therapies for osteoporosis and neural disorders, such as depression and Alzheimer's disease.
Researchers at Hebrew University of Jerusalem identified mechanisms allowing embryonic stem cells to become any cell type by examining epigenetic pathways and chromatin structure. This discovery could lead to the creation of cells in labs for treating Alzheimer's, Parkinson's, and other degenerative diseases.
Scientists at Hebrew University and Weizmann Institute discover interaction between proteins responsible for programmed cell death, allowing for potential anti-cancer therapies. The study's findings have the potential to stimulate apoptosis in cancer cells by interfering with protein regulation.
Researchers found that stressed grasshoppers consume more carbohydrate-rich plants, leading to changes in their excretions and affecting the microbes in the ground. This results in slower degradation of complex organic materials, impacting plant growth and field crop productivity.
A large international consortium has successfully sequenced the tomato genome for the first time, revealing its genetic code and potential applications in improving crop yields, flavor, and aroma. The achievement is expected to have significant implications for food production and culinary innovation.
A 16th-century Korean child's mummified liver has revealed a unique hepatitis B virus (HBV) genotype C2 sequence common in Southeast Asia, providing insight into the virus's evolution and spread. The ancient genome is the oldest full viral genome described in scientific literature.
Researchers at Hebrew University of Jerusalem have successfully generated neuronal cells from stem cells of Fragile X patients, paving the way for restoration of normal gene expression. The study identified a chemical compound, 5-azaC, that can clear methyl groups and reactivate FMR1 gene expression in both stem and neuronal brain cells.
Researchers at Hebrew University developed a method for training blind persons to use sensory substitution devices. Participants were able to read letters and words with sizes smaller than the international standard for blindness.
Research at Hebrew University and US researchers found a direct correlation between maternal overweight and increased tendencies towards adult child overweight, high blood pressure, and excess sugar and fat levels. This suggests that avoiding weight gain during adulthood may reduce these risk factors.
Hebrew University's Prof. Tamir Sheafer receives EUR 2.5 million EU grant with Belgian and Canadian colleagues to investigate information processing by politicians in a comparative perspective.
Researchers discovered a shorter half-life of nucleus samarium-146, shrinking the assessed chronology of events in the early solar system to a shorter time span. This new value is consistent with recent dating made on a lunar rock and other chronometers.
Researchers at Hebrew University have identified specific genetic pathways involved in autism, highlighting their potential for early diagnosis and treatment. The study found that different genes tend to be involved in specific brain processes, explaining similarities in behavioral symptoms across individuals.
Two distinguishable gene groups have been detected: one producing abundant biochemical products and functioning properly in most biological processes, and another with potentially abnormal function in diseases. The findings have significant implications for tailoring therapy to individual patients
New study reveals that learning from reinforcement can actually harm decision-making in complex environments like basketball. Despite past performance, players are more likely to miss the follow-up shot if they try again.
Researchers at Hebrew University and University of Vienna reveal stress-induced protein synthesis machinery that induces bacterial cell death in E. coli. This discovery may lead to the design of improved, novel antibiotics effective against pathogenic bacteria.
A study by Hebrew University researchers found that integration of input parts occurs even without conscious awareness, but awareness is needed when results are incompatible with expectations or prior knowledge. Conscious awareness plays a crucial role in dealing with novel situations.
Four Hebrew University professors, Prof. Saharon Shelah, Gershon Ben-Shakhar, Berachyahu Lifshitz, and Eliav Shochetman, have been awarded the $1 million EMET Prize for their significant contributions to mathematics, psychology, law, and Jewish law. The prize recognizes their far-reaching influence and impact on society.
Motherhood is associated with changes in brain function, particularly in the auditory cortex, enabling mothers to recognize and respond to pup distress calls. The study shows a rapid appearance of olfactory-auditory integration in lactating mothers.
Researchers found that lamin filaments are essential for proper gene positioning and organization, a crucial factor in maintaining nuclear shape and function. Mutations in lamin genes cause 14 different diseases, including Emery-Dreifuss muscular dystrophy, by disrupting muscle-specific gene reorganization.
Astronomers have discovered a correlation between gravitational wave events and radio flares, enabling them to pinpoint the source of these cosmic occurrences. By analyzing surrounding interstellar material, researchers can verify that detected gravitational waves come from specific regions of space.
A team of researchers at Hebrew University has discovered a way to block superantigen toxins that cause fatal immune storms. They created protein decoys that mimic the contact domain between superantigens and CD28 receptors, effectively inhibiting the immune response.
Hebrew University researchers have identified a key signal that prompts production of insulin-producing beta cells, which may help restore or increase beta cell function in people with type 1 diabetes. The study found that glucose levels trigger the regeneration of beta cells through a specific enzyme, glucokinase.
Egyptian fruit bats use an internal map to locate individual trees based on visual landmarks like lights or hills. The bats can bypass familiar trees to reach their favorite feeding site, suggesting a large-scale navigational mechanism beyond simple visual cues.
Researchers at Hebrew University identified the molecular basis for DNA breakage, a key feature of cancer development. The study sheds light on how DNA replication stress leads to breaks, providing new insights into cancer development and potential therapeutic approaches.
Researchers at Hebrew University have successfully identified and isolated 'organizer' cells in human embryos, which are responsible for determining the shape of the embryo during development. This breakthrough could lead to better understanding of embryonic development and potential applications in treating spinal damage.
A research group led by Prof. Chaim Cedar from the Hebrew University of Jerusalem has been chosen as one of the first three centers to receive funding under Israel's I-Core program. The center will focus on systems-level analysis of molecular biology and personalized therapy, with a goal of attracting top researchers back to Israel.
A collaborative research proposal by Hebrew University and University of Kentucky teams explores the role of small non-coding RNAs in regulating genetic information. The study aims to understand how organisms interpret genomic information, potentially leading to new therapies for human diseases.
A new nano-complex dietary supplement developed at Hebrew University can significantly reduce fat and sugar absorption in the body. The researchers found that taking this complex before a high-fat and high-sugar meal reduced bad cholesterol production by 42% and increased insulin sensitivity by 64%.
Octopuses have been shown to make complex movements, such as navigating through mazes, using visual information. The study reveals that they can direct a single arm in a coordinated movement to retrieve food rewards.
Researchers at Hebrew University discovered that insufficient building blocks in cancer cells lead to DNA damage. External supply of DNA building blocks can reactivate normal DNA synthesis and reduce cancerous features.
Hebrew University researchers have discovered a new mechanism by which tumor cells become invasive, involving a program of genes that confer invasive properties on epithelial cells. The study suggests that p53, a key tumor suppressor, may play a critical role in cancer prevention through its inhibition of cell invasion.
Researchers at Hebrew University have successfully doped semiconductor nanocrystals with impurity atoms, improving their electrical conductivity. This breakthrough could lead to the development of new electronic products, including nanolasers, solar cells, and sensors.
Prof. Chaim Cedar and Prof Aharon Razin were awarded the Canada Gairdner International Awards for their significant contributions to improving human life through genetic research. Their work deciphered the human genome project, revealing a new form of biological information through DNA methylation.
The Hebrew University of Jerusalem will digitize its Albert Einstein Archives with a $500,000 grant from the Polonsky Foundation. The project aims to preserve over 80,000 documents and make them accessible online.
Researchers at Hebrew University identified a previously uncharacterized type of bacterial communication mediated by nanotubes that bridge neighboring cells. This mechanism enables bacteria to exchange small molecules, proteins, and even small genetic elements, facilitating the acquisition of new features such as antibiotic resistance.
Researchers from Hebrew U. and US discovered how mercury gets into fish we eat by converting passive mercury to active form with bromine, a process found globally but more prevalent at Dead Sea due to high bromine levels.
A study by Hebrew University and French researchers reveals that the brain's Visual Word Form Area is co-opted for reading regardless of sensory input modality. Brain scans show identical activity patterns in blind and sighted readers, suggesting a task-oriented approach to reading.
Scientists at Hebrew University and Harvard have developed a low-cost, 'robotic' growth factor protein that speeds up wound healing. The protein responds to temperature, simplifying purification and enabling it to remain at the burn site, dramatically increasing healing rates in diabetic mice.
Researchers Prof. Tamir Sheafer and Dr. Shaul Shenhav found a 'negative democratic gap' in states such as Egypt, Iran, and Morocco, where citizens' aspirations for democracy exceed the actual level of democracy granted. This gap increases the likelihood of instability. On the other hand, countries with a 'positive democratic gap', like...
Researchers at Hebrew U. warn that climate change may cause many tree species with wind-dispersed seeds to become extinct due to reduced wind speed and increased seed production. This could lead to a slower spread of trees than expected, making them vulnerable to extinction.
Researchers at Hebrew University have discovered that basic assumptions about friction are wrong, providing a new means for replicating how earth ruptures develop and possibly enabling prediction of severe earthquakes. The findings offer unprecedented predictive power, estimating both rupture mode and extent of future earthquakes.
Researchers at Hebrew University found that induced pluripotent stem (iPS) cells undergo abnormal chromosomal changes, including trisomy and up-regulation of specific genes, which can lead to tumorigenic risk. This discovery hinders progress on using iPS cells in future therapy.
A Hebrew University-developed insect control method, applied in Mali, demonstrates a significant decline in malaria-bearing mosquitoes. The Attractive Toxic Sugar Bait Method (ATSB) significantly reduced mosquito populations and is considered a powerful tool for controlling malaria vectors.
Researchers at Hebrew University of Jerusalem discovered that Vav1 plays a wider role in several types of cancer than previously thought. The discovery has implications for targeting this gene in cancer research and identifying potential therapeutic targets.