The UC San Diego Center for Learning Health Systems Science will provide training for clinicians and researchers in the emerging field of learning health systems science. The center aims to improve patient outcomes, enhance healthcare efficiency, and increase diversity in the workforce.
A new wireless tracking system, developed by UC San Diego engineers, enables accurate localization of objects in dynamic environments. The system overcomes camera-based limitations and provides centimeter-level accuracy, opening up new possibilities for enhanced XR experiences.
Scientists have deciphered the assemblage of apical extracellular matrices in roundworms at the nanoscale using advanced microscopy. Defects in struts result in unnatural layer swelling, and the researchers found that collagens play a crucial role in maintaining matrix structure.
A UC San Diego study found biomarkers in blood that can help identify individuals at high risk of becoming suicidal, offering a new approach to personalize mental health care. The researchers also discovered sex-based differences in how depression impacts cell metabolism and identified potential targets for future drugs.
Researchers created a comprehensive map of the mouse brain using artificial intelligence and analyzed over 2.3 million individual brain cells. The findings help understand how genes are switched on and off to form different cell types, shedding light on human diseases like multiple sclerosis and neuropsychiatric disorders.
Researchers have found that RNA polymerase can recognize and transcribe artificial base pairs in the same manner as natural ones, paving the way for custom protein design. This breakthrough could revolutionize medicine by creating new medicines through designer proteins.
Research from the University of California San Diego finds that wildfires transform lakes and aquatic ecosystems, storing more carbon and emitting less CO2. The study suggests a shift in the role of aquatic systems in the global carbon cycle, with potential consequences for aquatic health and fisheries.
Researchers developed a mathematical model that accurately predicts gastrulation flows in chick embryos, which are similar to human embryos. The model then predicted cellular flows observed in frog and fish embryos, suggesting common physical principles behind multicellular self-organization across vertebrate species.
A new study estimates that living in flood-prone areas in Bangladesh is associated with an excess risk of infant mortality of 5.3 additional deaths per 1,000 births. The study found that children born during rainy months face a higher risk of death than those born in dry months.
Researchers analyzed data from the Centers for Medicare and Medicaid Services and found that some private insurers were reimbursing pharmacies at much higher rates than what they spent to acquire generic drugs. This can lead to higher out-of-pocket costs for seniors due to copayments and deductibles.
Scientists at University of California San Diego develop a new approach to microbiome research, identifying hundreds of molecules never seen before in the human body. They found a strong association between these molecules and inflammatory bowel disease, potentially leading to new diagnostic and therapeutic applications.
A recent study by researchers from the University of California San Diego has provided evidence that amino acids, the building blocks of life, can survive impact speeds of up to 4.2 km/s in Saturn's icy moon Enceladus' ice plumes. This finding has significant implications for the search for life beyond Earth.
A study published in Nature Communications reveals that the length of a food chain supporting newly hatched anchovies correlates strongly with population booms and busts. Shorter food chains are more efficient, resulting in more energy reaching anchovy larvae, while longer chains lead to less energy availability, causing busts.
Researchers at UC San Diego School of Medicine found that certain bacterial species dismantle protective molecules on vaginal cells, dysregulating cell turnover and response to surrounding bacteria. This study may help explain the association between bacterial vaginosis and adverse sexual and reproductive health outcomes.
Researchers linked hearing loss to microstructural differences in auditory areas of the temporal lobe and frontal cortex. The study suggests that compensatory brain changes may lead to increased dementia risk, and interventions like subtitles or speech-to-text apps could protect against this.
A new deep-learning platform, EUGENe, simplifies data analysis for genomics researchers. The software can be adapted to various projects and reproduces results from existing studies.
Researchers propose a new hypothesis that ECT alleviates depression symptoms by increasing aperiodic activity in the brain. Aperiodic activity helps boost inhibitory activity, slowing down neuronal cycles and effectively controlling how neurons turn on and off. The studies also found similar effects in magnetic seizure therapy.
Researchers developed a handheld, wireless biosensor to detect Alzheimer's and Parkinson's biomarkers from saliva and urine samples. The device has shown high accuracy comparable to existing state-of-the-art methods.
A study tracked skin temperature in 600 participants for six months, finding that individual differences were more significant than sex-based variations. The team used wearable devices to monitor skin temperature and found patterns consistent with menstrual cycles in women.
Scientists observe rapid evolutionary changes in bacteria and viruses, leading to the emergence of complex ecological patterns. The study reveals nestedness and modularity as two prominent repeating patterns in bacterial-phage interactions.
A recent report shows 37 percent of sampled drivers reported talking on their handheld cell phone while driving, highlighting the dangers of distracted driving. The UC San Diego TREDS program aims to educate the public on safe driving practices through free online courses and materials.
Research found online shopping for cigarettes and vape products increased 194% and 162% respectively after California's flavor restriction. This highlights the need for stronger regulations to include e-commerce retailers within retailer licensing programs.
A new mathematical model suggests that mammalian sperm cells exhibit two distinct swimming modes, which may be linked to fertilization. The model captures the interactions between motor kinetics and flagella deformations, revealing a second mode with stronger wave-shaped beating.
Scientists have discovered a genetic pathway between the heart and brain tied to fainting, suggesting that the heart sends signals back to the brain that can change its function. The study found that vagal sensory neurons play a key role in fainting, with their activation leading to rapid pupil dilation, suppressed heart-rate and breat...
Researchers at the University of California San Diego have created modular nanoparticles that can be tailored for various applications, including targeted drug delivery and neutralizing biological agents. By leveraging a plug-and-play approach, scientists can rapidly modify functional biological nanoparticles with ease.
New research suggests that meltwater flowing out to sea from beneath Antarctic glaciers is accelerating their retreat and contributing to global sea-level rise. The study's simulations indicate that this process could make a significant contribution to sea-level rise by 2300, potentially up to 15%.
A smartphone attachment developed by UC San Diego engineers can screen for neurological conditions like Alzheimer's disease and traumatic brain injury at low cost, accurately regardless of skin tone. The technology uses far-red light to enhance visibility of the pupil, making it easier to track changes in eye movement.
A team of researchers developed soft yet durable materials that glow in response to mechanical stress, using single-celled algae and a seaweed-based polymer. The materials demonstrate inherent simplicity, no electronics needed, and can be used as mechanical sensors or soft robotics, while also being resilient and self-sustaining.
Researchers at the University of California, San Diego have discovered a way to make ceramics tougher and more resistant to cracking. By using metal atoms with more electrons in their outer shell, they unlocked the potential to enable ceramics to handle higher levels of force and stress.
Scientists will use the Simons Observatory to uncover secrets hidden in the cosmic tapestry, revealing mysteries of the universe with unparalleled precision. The observatory's completion marks a major milestone in understanding the cosmos.
Engineers developed a nanoparticle vaccine targeting S100A9, a protein that attracts cancer cells to the lungs. The vaccine significantly reduced lung tumor growth and improved survival rates in mice with metastatic breast cancer after surgery.
Researchers at UC San Diego discovered that liver cells use vesicle exchange to share molecules and multiply, a process also found in various types of cancer cells. This mechanism could be a universal driver of resistance to cancer therapies targeting cell proliferation.
Scientists at University of California San Diego School of Medicine identified a new biomarker using single-cell RNA sequencing, which can predict whether neurons will regenerate after an injury. The study found that the biomarker was consistently reliable across various parts of the nervous system and developmental stages.
Researchers mapped gene switches and brain cell types associated with various neuropsychiatric disorders, including schizophrenia and bipolar disorder. The study also developed AI tools to predict the influence of individual high-risk gene variants on disease.
The new Global Center on Climate Change, Water, Energy, Food, and Health Systems program will address the impacts of climate change on rural and refugee communities in Jordan. The three-year program will focus on health effects research, health equity, intervention research, and training and capacity building.
Researchers measured metabolite concentrations of two herbicides in urine samples from Ecuadorian adolescents and found negative associations with attention, memory, and language. Glyphosate was also linked to social perception issues.
Engineers at UC San Diego developed wireless, battery-free force stickers that measure the force exerted by one object on another. The stickers can be used in various applications, including biomedical devices, industrial equipment monitoring, and inventory management.
Researchers created a unique, cell-by-cell atlas of the amygdala to identify potential new treatments for cocaine addiction. The study revealed connections between addiction behaviors and genes involved in energy metabolism, offering a brand-new way of thinking about the molecular biology of cocaine addiction.
Researchers studied how insects evolved two distinct flight strategies using robots and biophysicists. They found that asynchronous flight evolved together in a common ancestor, but some groups reverted back to synchronous flight.
Researchers at the University of California - San Diego developed screen-printed, flexible sensors that can record brain activity and lactate levels in earbuds. The sensors allow for long-term health monitoring and detection of neuro-degenerative conditions.
A new UC San Diego study suggests that the transparency rules in the Paris Agreement can keep many countries on track to meet their climate goals. The study found that naming and shaming is particularly effective for countries with strong democratic institutions and ambitious climate commitments.
Researchers at the University of California San Diego have developed nanoparticles that can deliver pesticide molecules to soil depths previously unreachable, targeting root-damaging nematodes. The technology holds promise for enhancing treatment effectiveness while minimizing costs and environmental toxicity.
The CDC has awarded a coalition led by UC San Diego researchers $17.5 million to develop innovative tools and networks for rapid response to emerging disease outbreaks. The project aims to integrate forecasting and analytic approaches with data to inform public health decisions.
Researchers have developed a sustainable solution to clean contaminated water using 3D-printed 'living material' containing genetically engineered bacteria that produce an enzyme to transform organic pollutants. The material's surface area and geometry optimize bacterial growth and decontamination efficiency.
Scientists have discovered that tissue-resident memory T cells can be enhanced to fight off infections and tumors by redirecting their cholesterol-making process. A drug and statins were found to boost coenzyme Q production in these cells, improving their effectiveness.
Women who maintained a stable weight were 1.2 to 2 times more likely to achieve exceptional longevity compared to those who lost 5% or more, with a 51% lower survival rate at age 90. Stable weight is associated with increased longevity in older women.
A new study from JAMA finds that physicians using social media are sharing and debating medical advancements, democratizing access to medical knowledge. The research team analyzed over 4 million #MedEd posts on X, revealing the potential of social media to accelerate medical science and improve practice.
A historic red tide event in 2020 was caused by an exceptionally dense bloom of Lingulodinium polyedra, a plankton species that can swim and outgrow its competitors, leading to harmful algal blooms. The study validated a 50-year-old hypothesis and highlighted the exceptional swimming ability of dinoflagellates.
Researchers found that specific regions of the genome with unique features act as hotspots for mutation accumulation in human cancer. Certain mutational signatures linked to alcohol consumption accumulate in early-replicated genome segments, defying conventional understanding.
A new study by UC San Diego researchers shows that time-restricted feeding can improve memory and reduce amyloid protein accumulation in mice with Alzheimer's disease. This approach may provide a simple and accessible way to correct circadian disruptions, which are the leading cause of nursing home placement.