A new study found that Medicare Advantage patients with colorectal cancer are six percentage points less likely to receive a cancer drug compared to those on Traditional Medicare. For non-small cell lung cancer, the pattern was not as clear due to limited low-cost treatment options.
A study published in Pediatrics found that nearly 25% of youth in Denver experienced homelessness or housing insecurity in 2021. The study used combined datasets and collaboration with agencies to estimate the true scope of the problem, highlighting a lack of resources due to undercounting.
Scientists found that 'memory cells' with past antigen experience kill cancer quickly but become exhausted faster. On the other hand, 'naïve' cells without prior experience exhibit robust expansion and resistance to exhaustion when targeted by specific genes like RUNX2.
Researchers characterize the mysterious C-terminal domain of dystrophin and its role in stabilizing cellular membranes across various tissues. The study reveals that dystrophin's CT domain interacts differently with two major dystrobrevin isoforms, driving differences in binding affinity and interaction modes.
A CU Anschutz study found that using a decision aid led to less personal uncertainty and distress among older adults, but not reduced depression. The online tool helped participants feel more confident in their decisions.
A large-scale clinical trial involving over 9,000 patients reveals that text message reminders failed to improve medication refill adherence over a year. The study included diverse representation from subgroups, including females, Hispanic ethnicity, and Spanish-speaking patients.
The University of Colorado Anschutz Medical Campus is developing a groundbreaking treatment for total blindness using whole eye transplantation. The $46 million award from ARPA-H will support research aimed at restoring vision to patients with total blindness.
The $2.7 million grant will support a network of research sites across the US and Latin America, investigating clinical characteristics and potential differences in care for Latinos with Down syndrome. The study aims to identify risk and resiliency factors that could change the presentation of Down syndrome in diverse cultural contexts.
A recent study published in Journal of Interprofessional Care highlights the importance of strong teamwork and face-to-face communication in improving patient care within hospitals. The research, conducted by researchers at the University of Colorado Anschutz Medical Campus, found that frequent in-person interactions between healthcare...
A new study from the University of Colorado Anschutz Medical Campus found a significant association between climate change and ocular surface eye conditions, particularly when particulate matter from air pollution was prevalent. The researchers discovered that clinical visits for ocular surface irritation and conjunctivitis more than d...
A new study from the University of Colorado found that animated characters with strabismus are more likely to be depicted as villains and unintelligent. The research analyzed 46 characters from 125 films and found a strong correlation between strabismus and negative portrayals.
Researchers mapped how HSV-1 enters the brain, infects critical regions, and triggers neurological diseases. The virus was found in areas controlling vital functions, such as sleep and movement, and interacted with immune cells that led to chronic inflammation.
A Colorado School of Public Health study reveals that gender affirming care patients experience disproportionately high levels of trauma, homelessness, and housing insecurity. Commercial insurance covers most treatments, but access to care varies by region.
A recent study by CU Anschutz scientists found that an ancient gene mutation among First Nations inhabitants of Oceania may make them more susceptible to certain infectious diseases. The allele, KIR3DLI*114, is widespread and unique to Oceania, with up to 30% of individuals carrying it.
A study led by CU researchers reveals that bedside interdisciplinary rounds build trust between patients and healthcare providers and within teams, leading to improved care experiences. Patients reported positive feelings about being involved in their care plans, while healthcare professionals reported respect and trust among colleagues.
Researchers analyzed crime statistics before and after sweep sites to find no change in most crimes, with only minor decreases in auto theft and public disorder. The study suggests that encampments cannot be linked to a rise in crime, challenging the effectiveness of sweeps in improving public safety.
The University of Colorado Anschutz Medical Campus has identified key opportunities to strengthen climate education for healthcare professionals. The authors propose a developmental learning model with six interconnected domains that build on foundational skills in communication and collaboration.
A new study published in JAMA Health Forum found that machine learning can be more effective than traditional methods for distributing scarce treatments to patients most vulnerable during a public health crisis. The model reduces expected hospitalizations by about 27 percent compared to actual and observed care.
A groundbreaking study finds that stress-induced changes in sperm motility occur after a stressful event, not during it, and improves sperm performance. Researchers observed changes in extracellular vesicles that play a role in sperm development and maturation.
A new research study by CU School of Medicine found that e-scooter injuries in Denver have become more frequent and costly over the past five years. The study suggests limiting e-scooter use at night and on weekends to reduce hospital costs associated with injuries.
A new study reveals that Latinx immigrant adults are extorted an average of $804 during their journey to the US southern border. The most common perpetrators were police officers and immigration officials. Experts say extortion should be considered an extreme stressor, which can inform mental health treatment for newly arrived immigrants.
Rates of methamphetamine-related psychiatric hospitalizations increased by 68% over the study period, while opioid-related hospitalizations decreased by 22%. The lack of resources to manage methamphetamine use is believed to contribute to this trend.
Researchers from the Linda Crnic Institute for Down Syndrome identified lower oxygen availability and dysregulated red blood cell function in individuals with Down syndrome. The study highlights potential targets for effective medical interventions to improve oxygen physiology in this population.
A new study provides first-of-its-kind data on the pharmacokinetics and safety of intravenous remdesivir in treating SARS-CoV-2 coronavirus in pregnant women. The research reveals that no dose adjustments are necessary for remdesivir when used in pregnant women, with no safety concerns or adverse pregnancy outcomes identified.
A clinical trial shows that JAK inhibitors improve autoimmune conditions such as alopecia areata, atopic dermatitis, and psoriasis in people with Down syndrome. The study also observed improvements in arthritis and decreased biomarkers of autoimmune thyroid disease.
A new study found that routine laboratory tests are not reliable for diagnosing Long COVID, with no biomarker among 25 clinical laboratory values providing a clinically useful diagnosis. The researchers suggest treating symptoms rather than relying on lab results to diagnose the condition.
A 20-year multicenter study found improvements in gender parity and career trends among internal medicine chief residents, with a significant increase in female participation and a rise in pursuing hospital medicine careers. The study also revealed new roles such as quality improvement and patient safety chief residents.
Researchers have identified distinct molecular and immune subtypes across individuals with Down syndrome, providing new insights for personalized medicine approaches. The study's findings could lead to tailored diagnostics and therapeutic approaches, addressing the unique manifestations of co-occurring conditions.
A study found that state-level insulin cost caps do not significantly increase insulin claims for patients with Type 1 or Type 2 diabetes. Most commercial enrollees were already paying out-of-pocket costs below the mandated caps.
New research from the CU Center for Combat Medicine and Battlefield Research found a promising pathway to reducing gun-carrying among youths with recent suicidal ideation or plans. Military-connected youth with past-year suicidal ideations or suicide plans exhibited lower rates of handgun carrying compared to their civilian peers.
A national research study found that a lack of institutional support is the top reason doctors are reluctant to discuss addiction with their patients. The study also highlighted knowledge and skill gaps as significant barriers to delivering evidence-based interventions.
Researchers discovered a new evasion strategy used by the varicella zoster virus to affect tissues far from the original site of infection. The virus uses small extracellular vesicles (sEVs) to package and shuttle a protein called IE62, which can travel to distant cells and shut down their antiviral response.
A new study sheds light on fatty liver disease MASH's pathology, revealing T cell activation and growth in response to poor diet. The research holds promise for developing a biomarker test to track disease progression before it's at a late stage.
A new study analyzed over a million patients' experiences with Medicare-funded end-of-life care. It found that Medicare Advantage Plans may offer less aggressive healthcare utilization near the end of life, including fewer hospitalizations and invasive medical treatments.
Public health researchers detail seven steps to regain public trust after the COVID-19 pandemic, emphasizing the need for accountability, communication, and addressing climate change. The report highlights critical challenges such as politicization, data system updates, and workforce improvement.
A collaborative study published in Lancet's eClinical Medicine found that prenatal maternal depression is a link to early birth, while intervention can reduce risk of early birth and newborn morbidity and mortality. Enhanced psychotherapy during routine prenatal care appointments led to reduced depression and longer gestation.
A new study found that nearly five percent of pancreatic adenocarcinoma patients achieve a pathological complete response (pCR) after treatment, leading to a 63% 5-year survival rate. The research highlights the importance of tailoring treatment based on factors such as chemotherapy regimens and radiation therapy.
A multicenter randomized trial identified a noninvasive ventilation method as effective in reducing the risk of hypoxemia and cardiac arrest during emergency tracheal intubation. The study found that this method cut the risk of hypoxemia in half and drastically reduced the risk of cardiac arrest compared to oxygen mask preoxygenation.
Antidepressants, such as SSRIs and SNRIs, work by restoring connections between brain regions, rather than correcting a chemical imbalance. The framework highlights the importance of these medications in alleviating depressive episodes, even if MDD isn't caused by a lack of serotonin.
A new computational machine learning method, STew, enables the joint analysis of spatial variation and gene expression changes. This technology may help researchers learn more about the spatial biology behind many different diseases and lead to better treatment therapies.
A recent study published by CU researchers found that 26% of physician respondents reported large ethical or religious barriers to participating in medical aid in dying, but many were willing to discuss MAiD with patients. Despite these barriers, physicians were less likely to participate directly in MAiD.
A new study by the Colorado School of Public Health found that high ICU occupancy levels during COVID-19 patients' stays contributed to increased mortality rates. The research highlights the critical need for tools to anticipate surges and effective resource management in healthcare systems.
Researchers at CU Anschutz Medical Campus identified key elements to improve diagnosis and treatment of coronary heart disease (CHD) in women, addressing the common misdiagnosis of heart attacks. The new guidelines provide recommendations to help clinicians better address sex-specific symptoms and treatments.
A national research effort found that eight weeks of endurance exercise training affected multiple bodily tissues and sparked widespread molecular responses in both male and female young adult rats. The study also revealed pronounced sex differences in some organs, such as the kidney.
A recent CU Anschutz study found that young people with youth-onset diabetes have a higher risk of developing neurodegenerative diseases like Alzheimer's. The study discovered specific blood biomarkers and elevated amyloid protein accumulation in the brains of participants, indicating an early onset AD risk trajectory.
Immediate electronic release of patient results can lead to misinterpretation and negative outcomes, as seen in CU doctor Benjamin Vipler's experience with his mom. The 21st Century Cures Act aims to empower patients with their health information but requires further study on its impact.
A nationwide training program aims to equip clinicians with digital tools for targeted fatigue, insomnia, pain, depression, and anxiety in cancer patients. The project will train 600 clinicians in technology-augmented care.
A study led by Emily Skeen, MD, found a strong correlation between neighborhood environmental and social conditions and the likelihood of exacerbation-prone asthma among children. The researchers used the Child Opportunity Index to predict the risk of severe asthma in urban areas.
A study published in Annals of Internal Medicine found that semaglutide is an effective therapy for metabolic dysfunction-associated steatotic liver disease (MASLD) in people with HIV. The medication, approved for type 2 diabetes treatment, showed significant reductions in liver fat and improved metabolic markers.
Researchers at the University of Colorado Anschutz Medical Campus have discovered a mechanism by which a bacterial virus limits Salmonella's ability to cause infection. By compromising protein synthesis, the virus can allow the host to rehabilitate and potentially treat resistant cases.