A researcher has found that individuals with Down syndrome have substantially altered key eye reflexes, leading to poor balance and motor coordination. The study's findings could lead to new tools for assessing the effectiveness of treatments aimed at improving quality of life.
A new study found children's hospitals are underequipped to handle a surge of patients in the event of a pandemic. The study urges health care institutions and government agencies to review emergency preparedness plans as flu season approaches.
Researchers found that NSAIDs inhibit COX-2, reducing tumor growth and metastasis. However, the safety of these drugs during pregnancy remains uncertain due to the complex changes occurring in the body after childbirth.
The University of Colorado Cancer Center has successfully genetically sequenced the most prevalent type of bladder cancer, urothelial carcinoma. The team discovered mutations in genes responsible for chromatin remodeling, which are similar to those found in other cancers.
A shortage of primary care physicians and limited access to these services are contributing to rising numbers of emergency department visits in the US. The study found that nearly 98% of Americans have health insurance coverage, yet barriers such as wait times and transportation issues remain a major challenge.
A clinical trial is underway at the University of Colorado to test a drug that could improve memory and learning in those with Down syndrome. The study, led by Dr. Alberto Costa, aims to enhance brain function and potentially increase hope for those affected.
Research finds that adolescents and young adults with type 1 diabetes have increased risk of heart attack and stroke due to atherosclerosis in the carotid arteries. The study aims to improve glycemic control and reduce cardiovascular risk factors to prevent cardiovascular disease.
Research reveals community gardens have numerous benefits, including improved relationships, increased civic involvement, and enhanced neighborhood quality. Gardening daily for just 20 minutes has been shown to boost health ratings, while gardeners report higher rates of moderate exercise and better eating habits.
A clinical trial revealed crizotinib's effectiveness in shrinking tumors and improving responses in over 60% of ALK-positive advanced non-small cell lung cancer patients. The treatment has shown dramatic benefits with minimal side effects, opening new avenues for targeted therapy.
A study found that 71% of elderly drivers supported mandatory retesting based on age, while 68% believed family members should decide if a license is revoked. The research aims to develop a screening test to identify higher-risk drivers and establish advance directives for driving decisions.
A new study shows that abiraterone acetate, a life-extending pill for advanced prostate cancer, prolongs survival by about four months compared to placebo. The medication also reduces PSA blood levels in patients with the disease.
The University of Colorado has received a $1.88 million grant to establish an 8-year curriculum track for primary care physicians, aiming to address healthcare gaps in rural and under-resourced communities. The program will recruit 10 high school students annually from diverse Colorado communities to pursue the BA/BS-MD program.
A recent study by University of Colorado researchers found that liposuction patients experience fat regain within one year, with redistribution to upper abdomen, shoulders, and triceps. Despite this, cosmetic shape benefits are retained, as participants reported being happy with their surgery results.
A University of Colorado School of Medicine researcher has won a $100,000 grant to investigate the cause of preeclampsia, which affects four to eight percent of pregnant women in developed countries. The goal is to find a central unifying factor behind the condition, which kills over 75,000 women and babies annually.
A new national survey of primary care physicians reports a significant increase in parental concerns about childhood vaccines, with 79% of physicians experiencing at least one vaccine refusal. The study highlights the need for more effective communication strategies to address these concerns and improve vaccination rates.
A research team at the University of Colorado Cancer Center has identified a new enzyme biomarker, ALDH1B1, present in nearly all colon cancer cells, which could help physicians diagnose colon cancer earlier and treat it more effectively.
Researchers at the University of Colorado School of Medicine found that people living at high altitudes have a lower chance of dying from ischemic heart disease and tend to live longer than others. Lower oxygen levels may spur genes to create blood vessels, reducing the risk of heart disease deaths.
Scientists have discovered that smells are processed by the olfactory bulb and cortex through a dialogue of rapidly firing nerve cells. This new understanding expands our knowledge of the complex process of smell detection and how it filters and categorizes odors.
Julien Langou receives $400,000 NSF CAREER award to study algorithms and their limitations in numerical simulations. His research aims to better understand how fast the fastest algorithm can execute on a given computing platform.
Researchers at the University of Colorado School of Medicine have discovered a drug that turns on a protective gene, protecting brain cells from degeneration. The drug, phenylbutyrate, has been shown to prevent the progression of Parkinson's disease in mice and is now being tested in humans.
A recent study published in the Journal of Thoracic Oncology has revealed that pemetrexed, an established chemotherapy drug, can produce significant responses in patients with anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer. The treatment was found to be effective in over half of these patients, offering n...
A University of Colorado study explores the relationship between hypoxia and inflammation, finding that a protein called HIF plays a key role in the body's response to low oxygen levels. The research may help patients who undergo organ transplants or suffer from infections or cancer
A new study found that implementing provider-based recall for immunizations is challenging due to lack of awareness and perceived difficulties. However, strategies such as dedicated staff and recalling children under two years old can facilitate recall initiation. The study suggests alternative approaches like population-based recall m...
A new gene test can identify which bladder cancer patients may have cancer spread in their lymph nodes, allowing doctors to determine the best course of treatment. The test analyzes 20 genes on tumor biopsies and has shown promising results in a large sample of patients.
A new program aiming to bridge the gap between body and mind has received a $3.9 million grant to create comprehensive, integrated healthcare systems in Colorado. The program, ACT, will engage local leaders to tackle fragmentation in healthcare and produce best practice models for whole-person care.
Researchers have identified a potential treatment for acute lung injury (ALI) and adult respiratory distress syndrome (ARDS) by switching the state of macrophages to a reparative state. This approach aims to stop ongoing inflammation and improve lung repair capabilities.
A recent study found that the number of women dying from complications of anesthesia during childbirth has plummeted 59 percent, thanks to better monitoring and medical techniques. The risks associated with general anesthesia have been dramatically reduced, but regional anesthetic-related deaths have slightly increased.
A new mouse model has been created to study how lipid sensing and metabolism in the brain relate to energy balance and body weight. The research found that mice with a deficiency of lipoprotein lipase in neurons became obese on a standard diet, leading to decreased food intake and increased sedentary behavior.
Researchers found that endothelin-A receptor antagonist drugs only reduce tumor growth at metastasis sites, not large tumors. These drugs block the action of protein ET-1, which stimulates cancer cell growth and spread.
A combination therapy of entinostat and erlotinib showed improved survival rates in patients with advanced non-small cell lung cancer (NSCLC) and elevated E-cadherin levels. The treatment was more effective than using erlotinib alone, leading to a large improvement in survival for patients with high E-cadherin expression.
A new study by the University of Colorado Denver has discovered a way to simultaneously desalinate water, produce hydrogen gas, and treat wastewater. The technology uses microbial electrolysis and desalination cells, which can generate pure hydrogen gas and facilitate desalination with an external power supply.
A study shows that a pregnant mother's diet impacts her infant's sense of smell, altering brain development and influencing future food preferences. The research found that exposure to odors in the womb can shape the brain's olfactory system, leading to preferred flavors in early life.
The University of Colorado is part of a broader FDA initiative to improve AEDs. The Denver pilot project aims to link AEDs to emergency medical dispatch, increasing bystander saves. Currently, AED locations are unknown in many places.
A citywide smoking ban has been shown to significantly decrease the prevalence of maternal smoking and pre-term births. In a study comparing Pueblo and El Paso County in Colorado, researchers found a 23% decrease in preterm births and a 37% decrease in maternal smoking after the ban took effect.
A study published in the New England Journal of Medicine found that over half of patients with a specific type of lung cancer responded well to a new targeted treatment called crizotinib. The medication targets the gene driving the cancer and has been shown to improve patient outcomes, including reduced tumor growth and improved qualit...
Researchers found that an infection late in pregnancy or after birth may trigger autoimmune process attacking the bile ducts, leading to scarring and blockage. This discovery points to new diagnostic tests and improved treatment options for biliary atresia.
A new study found that estrogen replacement therapy significantly speeds up ovarian cancer growth and increases the likelihood of cancer metastasizing to the lymph nodes. Researchers discovered estrogen-regulated genes specific to ER+ ovarian cancer that can be targeted with new anti-estrogen therapies.
Researchers found that video game training improves employee knowledge by 11%, skill-based knowledge by 14% and retention rate by 9%. Games work best when engaging users and provide flexible access.
Researchers at the University of Colorado Anschutz Medical Campus found a nonprofit weight loss program to be effective in reducing and maintaining weight loss. The study followed thousands of people enrolled in TOPS for three years, with participants losing five to seven percent of their body weight and keeping it off.
University of Colorado Cancer Center researcher Chuan-Yuan Li and his team have discovered that caspase genes, known as 'grim-reaper' genes, are the gatekeepers that allow differentiated adult cells to regress to undifferentiated stem-like cells. This breakthrough discovery could lead to more efficient use of induced pluripotent stem c...
The University of Colorado Cord Blood Bank has received a $6.3 million grant to collect and bank umbilical cord blood from minority groups, increasing genetic diversity and matching rates for minority patients. The bank will support an additional 5,000 cord blood units and expand collections to Arizona.
The NIH awarded a $2.4 million grant to increase diversity in the neuroscience field by preparing minority students and those with disabilities for careers in neuroscience. The grant will support undergraduates from two universities and provide seminars, mentoring, enhanced curricula, and hands-on research experience.
A recent study published in PLOS ONE suggests that brain abnormalities may underlie the development of antisocial behavior and drug abuse in boys. The research found significant differences in brain activity between antisocial boys and their peers, including reduced activity in regions responsible for decision-making and reward process...
Kendall Hunter will use non-invasive ultrasound measurements and invasive heart catheterization to diagnose and predict progression of PAH. The grant aims to improve diagnosis and treatment of this fatal disease in children and adults.
A new technique developed by Dr. Scott Oliver may revolutionize the treatment of eye cancer, preventing blindness in most patients by blocking up to 55% of harmful radiation with silicone oil.
A new study by University of Colorado Denver Business School researchers found that organizations learn more from failure than success and retain that knowledge longer. The study's findings suggest that managers should treat failures as invaluable learning opportunities, encouraging the open sharing of information about them.
The University of Colorado College of Nursing has received a $753,817 grant to develop an innovative master's program in nursing leadership and healthcare systems. The i-LEAD program aims to prepare advanced practice nurses with expertise in providing high-quality healthcare in rural and medically underserved areas. The program will pr...
A recent UC Denver study found that attractive women face discrimination when applying for certain jobs considered masculine, such as research and development or construction supervisor roles. In contrast, attractive men faced no similar disadvantage. The study highlights the existence of a double standard in hiring practices between m...
A University of Colorado School of Medicine study found that incorporating mentoring and group skill-building intervention programs for children in foster care may help improve mental health outcomes. The study demonstrated that treatment groups reported fewer symptoms of depression, dissociation, and posttraumatic stress, and better q...
Most pediatricians and family physicians administer the HPV vaccine, but fewer strongly encourage it for preteens. The study found that many physicians are not using effective strategies to ensure patients complete the full vaccination series.