A study found that nearly 20% of children use prescription medications, with 7.5% using multiple medications simultaneously. Adolescent girls are most vulnerable to harmful drug-drug interactions due to higher concurrent use of antidepressants and other psychotropic medications.
A $7 million grant will fund a 18-month study comparing two interventions: online CATCH-IT and in-person POD group therapy, to prevent depressive episodes among adolescents. The trial aims to identify which program has the greatest capacity for large-scale impact.
A study found that people with prediabetes who prefer to be active and alert later in the day tend to have higher body mass indices compared to those with morning preferences. This association is partly due to lack of sufficient sleep, which can increase the risk of obesity and diabetes.
Researchers at UIC are developing a new exosome-based approach to regenerate bone and tissues, with the goal of reducing side effects and advancing therapies. Engineered exosomes may aid regeneration faster than growth factors, with fewer complications.
Researchers at University of Illinois Chicago discovered that a mutation in the NPM1 gene helps improve sensitivity to chemotherapy in patients. The study found that patients with this mutation tend to respond better to chemotherapy and have higher rates of remission.
The study found that individuals from underrepresented communities are more likely to have positive scans and diagnosed lung cancer cases, highlighting the need for more expansive, risk-based screening guidelines. The researchers suggest considering additional factors such as a history of chronic obstructive pulmonary disease and socio...
A $2 million NIH grant will support research on how herpesviruses contribute to periodontitis and explore the potential of viral microRNAs as biomarkers for oral inflammation. The study aims to identify microRNAs that change in inflamed tissues and understand their impact on host immune cell functions.
A new microscopy technique allows researchers to visualize liquids at the nanoscale level, revealing unique properties of water and heavy water. The technique uses a specialized sample holder to trap tiny amounts of liquid, enabling high-resolution imaging and spectroscopy techniques.
Researchers have developed a novel delivery system using magnetic nanoparticles to target chemotherapy drugs to spinal cord tumors, which are difficult to reach due to the blood-brain barrier. This approach shows promise in treating intramedullary spinal cord tumors with improved survival rates and reduced side effects.
Researchers at the University of Illinois Chicago developed a magnetic surgical cement that can guide nanoparticles to lesions near spinal fractures, providing targeted drug delivery. The technology has the potential to become a surgical option for patients with primary spinal column tumors or metastasizing tumors.
Researchers have discovered a new reason lithium-oxygen batteries tend to slow down after few charge/discharge cycles due to lithium peroxide buildup in the electrolyte component. The buildup contributes to the loss of power and efficiency of these promising batteries.
Researchers at University of Illinois Chicago discovered that persistent binding of the Cas9 protein to DNA causes CRISPR failure. To improve efficiency, they found that consistent strand selection forces RNA polymerases to collide with Cas9, knocking it off DNA.
A protein called TWIK2 is crucial for activating inflammation, presenting a new target for developing drugs that can restrain excessive inflammatory responses. The discovery opens up the possibility of targeted anti-inflammatory drugs to modify its function and reduce inflammation.
Researchers found ketamine's rapid antidepressant effect is linked to the fast release of G proteins from membrane patches. This allows for better communication among brain cells, alleviating depressive symptoms. The long-lasting effects may be due to slow G protein re-entry into lipid rafts.
Researchers found that participants who followed a 16:8 diet consumed fewer calories, lost weight, and had improvements in blood pressure. The study suggests that daily fasting is an effective tool for weight loss in obese adults.
A new study reveals that supplement use among children has doubled since 2003, with adolescents using alternative medicines to treat health conditions or side effects of prescription medications. The prevalence of supplement use varies by gender, reflecting other health issues such as depression and insomnia.
Researchers used EEG to measure brain response to rewards in patients with depression and anxiety. They found that increased reward positivity was associated with symptom improvement, and those with blunted reward positivity responded better to antidepressant medication.
A study found that over 200 commonly used prescription drugs have depression or suicide listed as potential side effects, with concurrent use increasing the risk of depressive symptoms. The researchers suggest updating drug safety software and evaluating medication use in depression screening tools to minimize the impact of depression.
A study published in Acta Diabetologica found that people with diabetes and prediabetes who have lower sleep efficiency have poorer cognitive function than those with better sleep efficiency. The researchers also found that having diabetes was associated with lower cognitive function scores.
Research reveals that alcohol impairs microglial cells' ability to clear amyloid beta, contributing to Alzheimer's disease development. The study found altered gene expression for 312 genes under alcohol exposure.
Researchers aim to determine if stabilizing estradiol and progesterone can protect females at risk for suicide from increased depression and suicidal thoughts around menses. The study will compare symptoms of suicidality among participants in three experimental conditions: placebo, estradiol stabilization, and progesterone stabilization.
Research suggests that females with borderline personality disorder experience worsening symptoms during the perimenstrual window of their menstrual cycle. Symptoms such as depression and anxiety increase by at least 30 percent during this time, which is particularly concerning for individuals at high risk of suicide.
A study found a dramatic spike in cases of progressive massive fibrosis, the most severe form of black lung disease, among former US coal miners, particularly those working in smaller mines and longer hours.
Researchers at University of Illinois Chicago have created atrial cells from pluripotent stem cells using vitamin A. This breakthrough enables better study of atrial fibrillation and potential personalized treatments.
A new device has been developed to reduce radiation exposure in nanoscale-level imaging of living cells, allowing for more accurate and undamaged images. This innovation enables the study of biological, chemical, and materials science samples in their near-native environments.
Doctors at the University of Illinois Hospital have cured seven adult patients with sickle cell disease using compatible donor stem cells. The new transplant protocol allows for half-matched donors, significantly increasing potential donors and improving treatment outcomes.
Research found that having an evening preference is linked to a higher BMI among people with Type 2 diabetes. Participants with late breakfast times had a BMI of 28.4 kg/m^2, compared to those who ate earlier, who had a lower BMI by 0.37 kg/m^2.
A recent study published in PLOS ONE has confirmed the association of a chromosomal genetic variant with increased risk of atrial fibrillation (AFib) in Latinos. Latino individuals carrying the rs10033464 SNP at chromosome 4q25 are found to be at a 2.3-fold increased risk for developing AFib.
Researchers have identified a new class of antibiotics, odilorhabdins, which target bacterial ribosomes and disrupt protein synthesis. The unique compounds have shown potential in treating drug-resistant infections.
Researchers develop a heat-shock process to form high entropy alloyed nanoparticles from multiple elements. The resulting nanoparticles exhibit homogeneous crystal structures and potential applications as catalysts in emerging energy technologies.
Researchers at the University of Illinois Chicago are developing a small drug molecule that can block JAG1, a cell surface protein found on triple-negative breast cancer cells. The new therapy aims to reduce tumor growth and metastasis, with fewer side effects than aggressive chemotherapy or radiation.
Researchers at UIC and Argonne National Laboratory designed a new lithium-air battery that can operate in a natural-air environment without oxidation or buildup of undesirable byproducts. The battery achieved record-breaking 750 charge/discharge cycles, surpassing previous experimental designs.
Researchers at University of Illinois Chicago developed chimeric cells that can restore the structural muscle protein dystrophin in people with Duchenne muscular dystrophy, potentially avoiding the need for immunosuppressive drugs.
Researchers at University of Illinois Chicago developed graphene-oxide coated nanosheets to regulate lithium deposition, extending battery life and safety
A new study from the University of Illinois Chicago found no link between Tamiflu and increased suicide risk in pediatric patients. However, the researchers acknowledge that doctors will still prescribe the medication with caution due to other potential side effects and limitations in the study.
A new study reveals that the majority of mining-related injuries and illnesses in Illinois go unreported to the federal agency responsible for tracking these events. Researchers found that only 34% of cases were captured by the Part 50 program, highlighting the need for improved reporting rates.
A five-year grant will help researchers study arsenic's impact on pancreatic beta cells and the protective effects of selenoproteins. The study aims to identify factors that counteract arsenic's effects and potentially develop interventions for diabetes prevention.
Researchers at University of Illinois Chicago analyzed electronic health records to identify divergent scopes of practice for nurses and doctors. The study found that only 26% of patient records showed an overlap in terms, with average 4 related terms between professions.
Scientists at University of Illinois Chicago and Lawrence Berkeley National Laboratory have developed a technique to pinpoint chemical reactions inside lithium-ion batteries. This allows them to understand how batteries operate and identify ways to optimize performance.
Research found that transcranial direct current stimulation improves memory in people aged 18-35 but not those aged 60-79. The study tested 48 participants in each age group and found a 50% improvement in memory for younger adults immediately after stimulation.
Researchers at UIC will study molecular neurobiology of chronic pain and develop new drug treatments for sickle cell disease patients experiencing chronic pain. The funding aims to understand the role of protein kinases in chronic pain and identify potential therapeutic targets.
A new research project aims to determine why mine dust-related lung diseases are increasing in prevalence among coal workers. The study will use a multidisciplinary approach to examine the relationship between mine dust exposures and severe lung disease, with a focus on identifying critical risk factors.
Researchers discovered that glial cells increase the acidity of the extracellular environment when exposed to ATP, leading to a massive release of acid. This triggers a feedback loop that prevents over-excitability of neurons by inhibiting neurotransmitter release.
Researchers at the University of Illinois Chicago are investigating whether menstrual cup use reduces bacterial vaginosis and sexually transmitted infections in girls in Kenya. Studies have shown that menstrual cups can significantly reduce these infections by up to 52%.
Researchers at the University of Illinois Chicago have identified a small drug molecule that can clear HSV-1 infection in cells and works differently than current drugs. The new compound, BX795, has shown to be effective in treating resistant cases with minimal toxicity.
Researchers analyzed data from over 30 years of cardiopulmonary exercise testing and found that peak systolic blood pressure increases with age until 60, after which it plateaus. The study suggests lowering the threshold for exercise hypertension to identify younger adults at risk.
Researchers at UIC have identified a small molecule that promotes quorum sensing in Streptococci, stabilizing chemical signals between cells. This discovery may lead to new ways to manipulate bacterial activity and suppress virulence, potentially aiding in the fight against antibiotic-resistant infections.
Scientists developed a new technique to precisely measure the temperature and behavior of two-dimensional materials, enabling the design of smaller and faster microprocessors. They used scanning transmission electron microscopy combined with spectroscopy to measure the temperature at the atomic level.
The Learning Sciences Research Institute at UIC is studying how teachers learn and acquire knowledge to promote critical inquiry and deep reading in science, mathematics, and literature classrooms. The project aims to inform ideas about teaching practices that support student problem-solving and inquiry-based learning.
A new study found that binge drinkers have higher levels of microRNA-21, which may contribute to poor vascular function and increased cardiovascular disease risk. The researchers suggest that measuring microRNA-21 could help identify patients at risk of developing cardiovascular disease.