A new study published in JAMA Oncology finds that lack of insurance coverage is a major cause of delayed breast cancer screening and treatment among minority women. The research highlights the need for adequate health insurance to reduce racial outcome disparities in breast cancer.
Fossil record will be unique in Earth's history with many complete hominid skeletons, as human activities alter burial practices and increase animal density. The Anthropocene era will leave an unmistakable signal for paleontologists 100,000 years from now.
A new data science institute will focus on the theory and application of data science at UIC, developing a curriculum and promoting interdisciplinary collaborations. The institute aims to train the next generation of data scientists, particularly underrepresented groups.
The University of Illinois at Chicago will establish a Policy, Practice and Prevention Research Center (P3RC) to study various public health issues, including obesity and diabetes among Chicago schoolchildren. The center will also support researchers and community leaders in advocating for change and leveraging research data.
Researchers at the University of Illinois Chicago will conduct 3,000 eye exams among Latinos living in Chicago and Miami to study common eye conditions like glaucoma and macular degeneration. The goal is to identify patterns or causes of disease that can be prevented or slowed with treatment.
Researchers will evaluate how sleep-disordered breathing impacts chronic kidney disease progression, recruiting 2,200 adults from the CRIC study. They hypothesize that sleep apnea is associated with increased risk of chronic kidney disease progression due to its effects on blood pressure, insulin resistance, and organ damage.
Researchers discovered a new mechanism for detecting foreign material during early immune responses, which could help detect elusive cancers. ERAP1 protein can break down peptides bound to MHC I, allowing immune cells to recognize and destroy infected cells.
The University of Illinois Chicago has received a $300,000 grant to develop a screening process for prescribing opioids and managing opioid use disorders in cancer patients. More than 70% of cancer patients who receive radiation treatment use opiates, with higher rates seen in those receiving chemotherapy or having head and neck cancer.
A new study found that Class I drug treatment showed increased rates of AFib reoccurrence in obese patients compared to non-obese patients. The study suggests that obesity hinders the effectiveness of these medications, which could impact ethnic minority populations who are more likely to experience obesity and have poorer outcomes.
The University of Illinois Chicago will help young breast cancer survivors navigate post-treatment care and survival with a $1.8 million CDC grant. The program aims to reduce disparities in survival and quality of life due to social factors among breast cancer survivors.
Researchers at the University of Illinois Chicago found a peptide called PACAP links migraine pain and opioid-induced pain, offering potential new treatments for episodic migraines. The study's findings support the development of therapies targeting PACAP and its receptor.
Researchers at the University of Illinois Chicago report that robotic kidney transplants produce similar one- and three-year patient survival rates as those seen among nonobese patients. The study included over 230 robotic-assisted kidney transplants in patients with obesity, achieving dramatic reductions in post-surgery wound infections.
The University of Illinois Chicago and the Illinois Department of Public Health will improve maternal outcomes with a five-year federal grant. A new two-generation clinic and research center will provide comprehensive care to postpartum women and their newborns.
Researchers at the University of Illinois Chicago found that intermittent exposure to high levels of alcohol in adolescent animals leads to altered gene expression in adulthood. Blocking microRNA-137 in adulthood reverses or reduces the lasting effects of youth drinking, such as increased anxiety and alcohol use.
Researchers at the University of Illinois Chicago have identified a general mechanism governing crystal growth that scientists can manipulate when developing new materials. The 'dancing' barrier surrounding crystal-forming molecules is shown to fluctuate under different conditions, allowing molecules to break free and form crystals.
Researchers found that lower environmental quality in rural counties was associated with a higher prevalence of diabetes. In contrast, urban areas showed a stronger link between air and sociodemographic domains. The study's findings suggest a significant impact of cumulative environmental exposures on diabetes risk in rural populations.
New research from the University of Illinois at Chicago found that simultaneous masking significantly impacts care providers' ability to respond to medical alarms. The study, published in Human Factors, highlights the danger of hundreds of alarms daily being indistinguishable.
A study by researchers at the University of Illinois Chicago found that one in eight pharmacies in the US closed between 2009 and 2015. Independent pharmacies in urban areas are disproportionately affected, with nearly half closing due to lack of access to preferred pharmacy networks and 340B contracts.
Researchers have identified a new class of therapy for dry eye disease by targeting anti-citrullinated protein autoantibodies (ACPA) with antibody-based eye drops. The treatment has shown statistically significant and clinically meaningful reductions in corneal damage and symptoms in patients with severe dry eye disease.
Researchers have identified brain circuitry differences associated with suicidal behavior in individuals with mood disorders. The study found that those with a history of suicide attempts showed less connectivity in the cognitive control network and between it and the default mode network.
Researchers found decreased utilization among patients enrolled in a comprehensive care coordination model for Medicaid-covered children and young adults with chronic health conditions. Despite this, the mean cost of care remained nearly identical between groups, limiting savings from care coordination.
The University of Illinois Chicago has received $2.8 million in NIH funding to investigate non-opioid pain management solutions for adults with kidney disease. The study aims to find effective treatments to alleviate chronic pain and improve quality of life for patients on maintenance dialysis.
UIC researchers have successfully developed a fully rechargeable prototype of a lithium-carbon dioxide battery, demonstrating its potential for advanced energy storage systems. The battery's efficiency and long-lasting cycle life are significantly improved due to the use of new materials and a hybrid electrolyte.
Researchers at University of Illinois Chicago developed a system to deliver stem cells and provide mechanical stress for new bone formation. The addition of growth factors mimics embryonic bone development, leading to enhanced healing of bone defects in rat models.
Researchers have developed a hydrogel-based carrier that can deliver siRNAs directly to tumors, overcoming the challenge of rapid degradation and limited cellular entry. This innovative technology has the potential to improve the effectiveness of siRNA-based cancer treatments and enable more efficient delivery of biologics.
A new approach combines acyclovir with activated carbon particles to improve the effectiveness of a common herpes medication. The combination reduces viral load and inflammation while minimizing side effects like kidney damage.
Current artificial leaves convert only 15% of inhaled CO2 into fuel and release 85%, while new bipolar membrane technology increases efficiency to 60-70%
Researchers have identified a molecule called Gas6 that induces macrophages to clean up cellular debris and reduce inflammation. Boosting Gas6 levels in macrophages has been shown to resolve inflammation in mouse models of acute lung injury, holding promise for treating diseases such as heart disease, cancer, and rheumatoid arthritis.
Scientists have successfully imaged an exotic quantum particle called a Majorana fermion, which can be used as a building block for future qubits and the realization of quantum computers. This achievement brings researchers closer to developing robust qubits and ultimately building quantum computers.
Researchers have identified unique populations of neurons and associated cells in the spinal cords of patients with ALS, which could serve as useful biomarkers for earlier diagnosis. The study found different types of motor neurons and microglia present in less affected regions of patients with focal-onset ALS.
Patients with Type 1 diabetes who are obese often face denied pancreas transplantation due to high infection risks. However, robotic pancreas transplantation has shown promising results, reducing blood loss and surgical complications while improving patient outcomes.
A chaotic household environment is associated with worse asthma control in urban minority children, according to a new study published in Pediatrics. The researchers found that parent and childhood depressive symptoms are linked to poorer asthma outcomes, while family chaos explained part of this relationship.
Scientists have captured atomic-level images of active CRISPR enzyme Cas9, providing new structural information on its mechanism. The images show how the enzyme cuts DNA strands and reveals the importance of domain movement during reaction, which could lead to improved genome-editing tools.
Researchers studying a $750,000 grant at the University of Illinois Chicago aim to understand how various mining dusts contribute to lung disease. They plan to collect dust samples and expose mice to different combinations to determine the most damaging mixtures.
Research suggests that PI3K inhibitors, a new class of cancer drugs, may cause an increase in pre-cancerous lesions in the pancreas of mice fed high-fat diets. The findings urge doctors to consider a patient's weight before prescribing these drugs, especially for those with pancreatic cancer who are obese.
Researchers developed a controlled microfluidic crystallization device to improve screening of drug substances and scale up stable crystallization. The device can simulate industrial conditions and screen various APIs, including anti-inflammatory drugs, with higher efficiency.
The University of Illinois Chicago is collaborating with TB Alliance to develop new clinical-stage drug candidates for treating tuberculosis, a bacterial infection resistant to available antibiotics. The five-year research project aims to produce two new treatments, with UIC receiving up to $9 million in funding.
Researchers have developed a process for 3D printing biological tissues without scaffolds using stem cells in a hydrogel bead bath. The printed cells form stable connections and mature into functional tissues, offering potential applications in tissue engineering and regenerative medicine.
Research reveals pressure-sensing protein piezo 1 plays a key role in lung edema development. Suppressing its activity or bolstering adherens junctions may prevent fluid entry into the lungs.
A new study finds that many Philadelphia pharmacies fail to implement Pennsylvania's standing order for naloxone nasal spray, putting communities at risk. The study suggests that policies need to be enforced and pharmacies held accountable for implementing them.
A new technique developed by researchers at the University of Illinois Chicago and the University of Pennsylvania uses stem cells and flexible implantable bone-stabilizing plates to help speed up bone healing. By mimicking embryonic conditions, this technique encourages stem cells to differentiate into cartilage and bone.
A new study found that Latino and black households have a greater negative environmental impact per dollar spent on food due to their purchasing patterns. They tend to buy more environmentally intensive foods like grains and protein, and spend more money overall.
A recent US study found that 81% of antibiotics prescribed by dentists to prevent infections prior to dental visits are unnecessary. The study highlights the need for improved antibiotic stewardship in dental practices, particularly in Western US locations.
Researchers discovered African mole-rats are insensitive to allyl isothiocyanate, the active ingredient of wasabi, due to unique nerve structure leak channels. This finding may lead to new pain relief methods without addiction risks.
Researchers found US dentists prescribe 37 times more opioids than UK counterparts in 2016, a peak year in the US opioid crisis. The study emphasizes the importance of adopting national guidelines for treating dental pain and promoting judicious opioid prescribing among US dentists.
Researchers found that new neurons continue to form well into old age, including in people with cognitive impairment and Alzheimer's disease. The study provides evidence that neurogenesis may moderate the effects of brain pathology, suggesting potential therapeutic possibilities.
Research reveals that male fruit flies' genitals remain preserved in size even when food is scarce, allowing them to reproduce more successfully. This preservation is linked to lower levels of a growth factor called FOXO, which acts as a brake on growth and size maintenance.
The University of Illinois Chicago will launch a program using community health workers, social workers, and doulas to improve health outcomes for pregnant women and their children in historically underserved neighborhoods. Maternal mortality rates are disproportionately high among black women, prompting the initiative.
Researchers are conducting a multi-center study to determine which medication, azithromycin or roflumilast, is more effective in reducing the risk of death and hospitalization in people with COPD. The clinical trial will enroll over 3,000 patients at 30 centers across the US.
A phase I/II clinical trial of an enzyme-based treatment found reduced signs of disease and discomfort in participants with severe dry eye disease. The treatment, DNase, was shown to be safe and effective in improving corneal health and reducing symptoms.