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Washington University in St. Louis


Bringing expansion microscopy to plants

Researchers have developed ExPOSE, a method that allows for the visualization of plant cells with greater resolution, enabling studies on protein and RNA location, and cellular response. The technique uses protoplasts to overcome cell wall challenges, paving the way for a powerful new toolkit in plant biology.

SourceWashington University in St. Louis·JournalThe Plant Journal·DateMar 7, 2025

Electrochemical field key to how dementia precursors ‘break bad’

A study by Washington University in St. Louis researchers has found a critical role for the physical interfaces of amyloid beta peptides in determining their chemical dynamics, leading to neurodegeneration. The research identified small molecules capable of breaking the toxic feedback loop, providing evidence that proper nutrition may ...

SourceWashington University in St. Louis·JournalJournal of the American Chemical Society·DateFeb 26, 2025

Study identifies benefits, risks linked to popular weight-loss drugs

A recent study published in Nature Medicine analyzed over 2 million veterans taking GLP-1RA medications, finding benefits to cognitive and behavioral health while revealing increased risks for pancreatitis and kidney conditions. The study also showed decreased risks of seizures, addiction, suicidal ideation, and neurocognitive disorders.

SourceWashington University in St. Louis·JournalNature Medicine·TypeData/statistical analysis·DateJan 20, 2025

Coyote genes may show urban evolution at work

A new study explores how city life is influencing the evolution of urban coyotes, revealing genetic changes related to diet, health, thermoregulation, behavior, cognition, and reproduction. The research also highlights the challenges of studying urban coyotes, which are increasingly common in urban areas throughout the US.

SourceWashington University in St. Louis·JournalGenome Biology and Evolution·DateJan 15, 2025

Nothin’ but pawpaws in the pawpaw patch

New research from Washington University in St. Louis found that pawpaw patches reduce herbaceous plant species diversity and total understory community size, creating a habitat where the rules of competition are more random. The presence of pawpaws also makes it challenging for land managers to encourage the growth of understory species.

SourceWashington University in St. Louis·JournalEcosphere·DateJan 9, 2025

Archaeologists report earliest evidence for plant farming in east Africa

Archaeologists have uncovered evidence of early plant farming in east Africa, revealing a pattern of gradual introductions of different crops that originated from different parts of the continent. The study found domesticated cowpea, sorghum, and finger millet seeds dating back to around 2,300 years ago.

SourceWashington University in St. Louis·JournalProceedings of the Royal Society B Biological Sciences·DateJul 9, 2024

Heart disease model puts cells to work

Researchers develop a model of heart disease by tricking stem cells to behave like mature heart cells with a mutation that causes hypertrophic cardiomyopathy. The study reveals the connection between mechanical stress and electrical function in hearts, shedding light on why genetic mutations can cause arrhythmias.

New technology allows researchers to precisely, flexibly modulate brain

A new technology combining holographic acoustic devices with genetic engineering allows precise targeting of affected neurons in the brain, potentially treating neurodegenerative diseases. The technique, AhSonogenetics, uses a noninvasive wearable ultrasound device to alter genetically selected neurons in mice, alleviating Parkinson's-...

SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·DateJun 17, 2024

Helping qubits stay in sync

Researchers at Washington University in St. Louis have developed a new technique to enhance quantum entanglement stability in qubits. This breakthrough addresses the challenges of maintaining coherence and reliability in quantum systems.

SourceWashington University in St. Louis·JournalPhysical Review Letters·TypeExperimental study·DateMay 23, 2024