Researchers discovered a bacteriophage virus in Connecticut that targets multi-drug resistant Pseudomonas aeruginosa, making it susceptible to existing antibiotics. This 'phage' therapy has the potential to treat life-threatening infections and preserve medical options against deadly bacteria.
A team of Yale scientists has created a more exotic type of Schrödinger's cat-like state that can exist in two boxes simultaneously, leveraging entanglement to enable error correction and logical operations in quantum computing. This breakthrough builds upon decades of development in circuit quantum electrodynamics.
Researchers at Yale University have found a way for antibodies to enter the nervous system, allowing them to control viral infections. This discovery may lead to new treatments for conditions such as herpes and Guillain-Barre syndrome.
Researchers developed bioengineered blood vessels that appear safe and functional after implantation in dialysis patients. The vessels showed no signs of rejection and maintained their mechanical integrity, with a 90% durability rate compared to traditional synthetic grafts.
A new study published by Yale School of Medicine researchers found that heart attack rates are trending down nationwide, but lower-income communities continue to experience higher hospitalization rates for acute myocardial infarction. Despite similar declines in heart attack rates across all income levels, low-income communities have n...
Despite federal legislation, Yale researchers found that shortages for acute-care drugs used to treat critically ill patients have increased since the passage of FDASIA. The median duration of these shortages was approximately eight months, posing risks of medical error and reduced effectiveness.
A new Yale-led study finds that older adults are more susceptible to flu due to a reduced antiviral response, leading to increased inflammation and damage. Researchers propose targeting inflammation to combat flu in vulnerable patients.
A new HPV vaccine could significantly reduce cervical cancer incidence by 73% and healthcare costs if states coordinate policies to improve coverage. Increased funding can lead to improved vaccine coverage and public health.
Researchers from Yale, Oxford, and Imperial College London describe a new species of ancient arthropod that carried its young in capsules tethered to its body. The creature, named Aquilonifer spinosus, lived about 430 million years ago and had unique brooding strategies to protect its eggs and embryos from predators.
The study highlights the importance of time context in diet reconstructions, which can lead to conflicting results. By considering different time scales for dietary proxies, scientists can gain a more accurate understanding of an animal's eating habits.
A new study published in Pediatric Obesity found that eating a second breakfast at school is associated with healthier weights and reduced risk of obesity among middle school students. The study, which tracked 584 students over two years, found that students who ate double breakfasts were less likely to be overweight or obese compared ...
A Yale-led team of paleontologists has determined that the Tully Monster, a 300-million-year-old animal with teeth at the end of a narrow head extension and eyes on either side of a long bar, was a vertebrate with gills and a notochord. The discovery sheds light on the creature's likely predatory lifestyle.
New research reveals that African Americans are less likely to start smoking in late teens but continue smoking into later years, leading to lower average pack-years and reduced eligibility for lung cancer screening. This disparity results in higher risk of death from tobacco-related diseases among African Americans.
Researchers found that mitochondria in brain cells rapidly change shape and function in response to high blood sugar levels, affecting peripheral tissue functions. The study suggests that alterations in this mechanism may be crucial for type 2 diabetes development.
A Brazilian woman infected with Zika virus had a stillborn baby with severe tissue swelling and central nervous system defects, suggesting the virus may cause damage outside the CNS. The case raises concerns about the risk of stillbirths and other adverse outcomes in pregnant women exposed to the virus.
Less than 40% of clinical trial results were shared within two years, according to a new study published in the British Medical Journal. Researchers at Yale School of Medicine found significant variation across academic medical centers, highlighting the need for timely and transparent result sharing.
A Yale University study found VA hospitals to have slightly lower mortality rates among older men with specific conditions, but higher readmission rates compared to non-VA hospitals. The differences were small, indicating that the VA healthcare system is doing comparatively well for these vulnerable patient groups
Researchers at Yale University found that testosterone therapy significantly improved sexual function, including sexual activity, desire, and erectile function, in men over age 65. Additionally, testosterone treatment showed modest benefits in terms of improved mood and fewer depressive symptoms.
A Yale University study found that infant girls at risk for autism exhibit better social attention and observational skills than boys, which may help prevent or mitigate the severity of autism symptoms in high-risk females.
A Yale study applying evolutionary biology tools sheds light on cancer's genetic origins and tumor progression. The research mapped genetic mutations in normal, primary, and metastatic tumor tissue, revealing that metastases originate from different paths within primary tumors and can diverge early in cancer history.
Researchers found that guideline-concordant care, including mental health services and substance abuse treatment, can significantly reduce the risk of death for patients on opioid painkillers. Patients who received these services were 50% less likely to die within six months.
A study published in The BMJ found that moderate exercise programs can help prevent life-changing falls in older men. The research, which involved 1,635 participants aged 70-89, showed a notable gender difference, with male participants experiencing a 38% reduced rate of serious fall injuries.
A Yale University study found a significant correlation between states' social service spending and reduced HIV/AIDS case rates and deaths. The researchers analyzed data from 2000-2009, discovering that states with higher investments in public health and education per person living in poverty had lower HIV/AIDS rates.
A study by Yale University researchers found that very few women undergo bilateral salpingectomy with ovarian conservation during hysterectomies for non-cancerous conditions. The procedure may help protect against ovarian cancer and preserve hormonal levels, but its use varies widely among hospitals across the US.
A new quality measure has been developed to track the variation in colonoscopy quality among outpatient facilities using follow-up hospital visits. The study found that 16.3 per 1,000 outpatient colonoscopies result in unplanned hospital visits, with significant variation across facilities.
A new study reveals that small ponds globally produce an outsized share of greenhouse gases, particularly carbon dioxide and methane. These tiny bodies of water, less than a quarter acre in size, account for significant emissions due to high concentrations of terrestrial carbon.
Researchers found that the brain prioritizes calorie intake over taste quality when it comes to sugary foods. The study suggests that the brain has two separate pathways for processing sweetness and energy signals, with calorie-rich foods dominating our desire for sweets.
A new study suggests that continent-scale monsoons will adapt gradually to climate change, with changes in land use and greenhouse gas concentrations prompting adjustments in massive air circulations. Despite predictions of a sudden shift, the researchers argue that monsoon rainfall will change smoothly over time.
A Yale University study found that the hormone FGF21 protects against age-related loss of immune function by promoting T cell production. Increasing FGF21 levels may be an additional strategy to bolster immune function in the elderly or cancer patients undergoing bone marrow transplantation.
A Yale team discovered that a high-fat diet can disrupt pathways involved in synaptic plasticity and metabolism, leading to depression-like symptoms. Ketamine reverses these effects, suggesting a potential solution for treating depression associated with metabolic disorders.
A Yale University study found that group prenatal care substantially improves health outcomes for both mothers and their infants. Women who received group care had lower rates of small birth size, preterm delivery, and low birthweight compared to those with individual care.
A Yale-led study suggests that species rarity may be a key indicator of mass extinctions, which could provide an early warning system for the current biotic crisis. The researchers propose that monitoring changes in species and ecosystems can help scientists pinpoint mass extinctions before they become catastrophic.
Researchers found that telomeres slow down and sometimes even reverse with weight loss and exercise in breast cancer survivors. Higher body fat levels are associated with shorter telomere length.
A Yale-led study finds that individuals with negative beliefs about aging are more likely to develop brain changes associated with Alzheimer's disease. Combatting these negative beliefs could potentially reduce the rising rate of Alzheimer's disease.
Yale researchers developed a high-dose flu vaccine strategy that lowered infection rates by 64% among patients with immune system cancers. The novel dosing schedule improved protection against all flu strains in 66% of patients, offering promising results for cancer patient populations.
Novel antiviral therapies for hepatitis C have transformed treatment, effectively reducing HCV in over 90% of cases. Enhanced screening and treatment efforts could virtually eliminate the disease within a decade by increasing treatment rates four-fold.
A recent Yale University study found that black women with stage I-III cancer are less responsive to neoadjuvant chemotherapy compared to other racial groups. Despite presenting with more advanced-stage and aggressive tumors, the findings suggest biologic differences or disparities in treatment may be contributing factors.
Researchers at Yale and Harvard have found a galaxy with a heartbeat, detecting the effects of pulsating older red stars on its light. The mean pulse of the stars in M87 is about one beat every 270 days.
A new class of type 2 diabetes drugs, SGLT2 inhibitors, have been shown to significantly reduce hospitalizations and deaths from heart failure. The EMPA-REG trial found that patients treated with the drug experienced significant reductions in blood sugar, blood pressure, weight loss, and major hospitalizations for heart failure.
A Yale study published in JAMA found that the proportion of non-acute PCIs classified as inappropriate decreased from 26% to 13% between 2010 and 2014. This decline was attributed to improved clinical decision-making, documentation, and national performance improvement campaigns.
Researchers have found that young stars in Serpens South form through distinct, episodic growth spurts. CARMA-7 experienced 22 episodes of gravitational push-pull during star formation, indicating a chaotic environment common for star birth.
Researchers at Yale University found that a large achievement gap between dyslexic and typical readers is already present in first grade. Early screening and reading interventions can help close this gap by implementing programs as early as kindergarten.
A new study found that only half of younger heart attack patients believed they were at risk before the attack, with women being less likely to be informed by their doctors. The study highlights a need for better education and counseling on heart disease prevention among young individuals, particularly women.
A new study by Yale School of Medicine researchers found that high post-pregnancy body mass index (BMI) is a significant risk factor for pelvic organ prolapse. Maintaining a healthy weight after delivery may play an important role in preventing early stages of prolapse, according to the research.
Researchers at Yale University have developed a synthetic process to synthesize glucosepane, a critical chemical link in both diabetes and aging. This breakthrough may lead to the development of tools to examine the role glucosepane plays in human health and potentially inhibit its formation.
Researchers at Yale University have identified a rare genetic mutation that significantly extends the survival of lung cancer patients with brain metastases. Patients with this mutation live an average of four years with controlled disease in their brains nearly a year after initial treatment.
A Yale University study found that varenicline was 46% more effective in women after three months of treatment, leading to higher abstinence rates. The drug's effectiveness for women may be due to differences in the nicotine receptor system in the brain.
Researchers at Yale University have found that hunger neurons control not only hunger and appetite but also regulate bone mass. The study reveals that lower levels of hunger are associated with lower bone density, highlighting a new mechanism in the regulation of skeletal bone metabolism.
Yale University scientists have designed a new chemical compound that mimics the properties of nitrogenase, an enzyme responsible for natural nitrogen fixation. The findings could lead to the development of synthetic catalysts that turn nitrogen into ammonia, reducing transportation and production costs.
Researchers translate microscopic concepts to study polar sea ice, capturing dynamic forces with a tractable equation. The new approach opens up climate science to nonequilibrium statistical mechanics methods, solving the long-standing challenge of measuring sea ice volume.