Articles tagged with Genetic Technology
Scientists have pinpointed the FCER1A gene as a major factor in allergic diseases, influencing IgE antibody production and leading to conditions like hay fever and asthma. The discovery has potential for guiding new drug development.
Researchers at Mount Sinai School of Medicine have developed a new gene silencing technology that can effectively suppress transcriptional expression of targeted genes in human cells, including those linked to various diseases. This breakthrough could pave the way for preventing diseases where gene dysfunction plays a role.
Researchers propose steps toward a solution, including technology assessments by independent organizations, to identify beneficial and safe devices. This would increase awareness among health professionals of new technologies' potential promise and pitfalls.
Researchers have developed a new technique that combines gene chip technology with fast-sequencing machines to enable rapid and accurate sequencing of specific genomic sequences. This technology has the potential to replace traditional methods such as PCR for many purposes, allowing for faster and more efficient genome sequencing.
Researchers at The Feinstein Institute for Medical Research have discovered a new gene that increases the risk of developing schizophrenia. The study, which analyzed over 500,000 genetic markers, found a significant link between a chromosomal region called PAR1 and the disease.
Sequenom's Fetal Nucleic Acid Technology shows promise in detecting fetal DNA in maternal blood, potentially diagnosing genetic defects early in pregnancy. This approach could benefit all expectant mothers, particularly those with high-risk pregnancies.
Dr. Progulske-Fox received the Basic Research in Periodontal Disease Award for her work on P. gingivalis and its interactions with human cardiovascular cells. Her research aims to identify virulence genes that could lead to the development of new diagnostic tests, vaccines, and treatments for periodontal and cardiovascular diseases.
Researchers identified mutations in the AIP gene as the underlying cause of pituitary adenoma predisposition. The discovery provides molecular tools for efficient identification of predisposed individuals, potentially leading to earlier diagnosis and treatment of conditions like acromegaly and gigantism.
Xiaolian Gao, a UH biology and biochemistry professor, is among the 24 honorees for her DNA chip research that has the potential to make complete functioning organisms. Her technology could lead to alternative energy sources, natural product synthesis, and gene therapy procedures.
The Genetics and Public Policy Center at Johns Hopkins University will launch a new genetic-testing initiative to build consensus on the safe and accurate use of genetic testing. The two-year $3 million grant aims to improve our understanding of genetic tests and their impact on public health.
A panel discussion at the American Association for the Advancement of Science annual meeting explores issues of public confidence in genetic technologies. Stanford University School of Medicine associate professor Barbara Koenig addresses concerns about regulating new genetic technologies and ensuring their effectiveness.
Nanosphere's nanoparticle-based technology allows for rapid and highly-sensitive single nucleotide polymorphism genotyping without gene amplification. The technology can detect a specific gene and its mutation extent with greater than 99 percent confidence threshold.
The NIEHS is developing a new RNAi library to better understand the effects of environmental toxins on human health. This technology will help researchers identify specific genes responsible for adverse responses to chemicals, ultimately aiding in the development of new disease prevention strategies.
A study funded by the Christopher Reeve Paralysis Foundation has identified novel potential therapeutic targets for spinal cord repair using microarray technology. The study analyzed 108 genes and found patterns of gene expression that could help researchers identify new treatments.
Researchers have developed a method to detect all cystic fibrosis mutations with 100% accuracy using microarray technology. The technology could be used to diagnose genetic diseases during preimplantation genetic diagnosis, providing rapid and reliable results.
Scientists at Fox Chase Cancer Center successfully extracted high-quality RNA from archived tissue samples using the Paradise Reagent System. This innovation allows researchers to identify genetic changes in cancer that span years, enabling personalized therapy.
David Botstein, known as 'The Father of Modern Genetics', was awarded the 2003 Gruber Prize for his groundbreaking work on human genetic mapping and the discovery of transposons in bacteria. He will continue to lead research at Princeton University's Lewis-Sigler Institute for Integrative Genomics.
Researchers found a genetic connection between blood flow patterns and cardiovascular disease, with oscillatory shear stress leading to increased expression of the protein BMP4. This finding may help explain why physical inactivity promotes heart disease and could lead to new diagnostic tests or gene-based therapies.
The collaboration aims to extract DNA from diverse ecosystems and sequence it using JGI's capabilities. This will provide a vast resource of genetic material for scientists to study and develop new products, including pharmaceuticals, agricultural solutions, and energy sources.
Most Americans oppose scientists working on human cloning (76%) and favor government regulation of reproductive genetic technologies. The public draws clear distinctions between health and non-health related applications, with two-thirds approving of testing for serious diseases.
A new chip technology is being developed to analyze cancer genes, promising faster and more accurate diagnoses. The technology uses DNA microarrays to screen thousands of genes simultaneously, allowing for quicker testing than current methods.
A genomic study has identified 149 genes that are turned on or off during simulated asthma attacks in cynomolgus monkeys. The study uses microarray technology to analyze gene expression changes, providing valuable insights into the genetic regulation of asthma.
A new analysis method developed by Johns Hopkins Medicine allows for faster and more accurate determination of the human genome sequence. The technique identifies highly reliable data points within microarray sequences, enabling researchers to examine genetic variations linked to diseases such as high blood pressure and schizophrenia.
The RNA Invader assay directly detects gene expression levels without sample contamination, allowing for accurate quantification of small changes in biologically significant genes. This technology also discriminates between nearly identical RNA sequences, enabling researchers to identify specific targets with consistency.
Couples seeking preimplantation genetic diagnosis (PGD) for single gene disorders or to avoid chromosomal abnormalities have differing views on embryo destruction and genetic trait selection. The study found that most couples prioritize having a healthy child over preventing genetic transmission of inherited mutations.
The RNA Invader assay directly detects gene expression levels from crude cell samples, eliminating costly and time-consuming steps. This technology allows for precise quantification of small changes in biologically significant genes.
NASA and Lockheed Martin have agreed on a plan to proceed with the X-33 space plane program, including the use of aluminum fuel tanks for hydrogen fuel. The restructured plan focuses on milestone payments and mission safety, with the goal of reducing launch costs.
Researchers at Rosetta Inpharmatics used Flexjet DNA microarray technology to analyze the role of changes in chromosome number on gene expression, showing large-scale biases that affect cellular processes. The study provides a novel tool for evaluating aneuploidy and its potential applicability to human cancer cells.
A new vaccine technology has demonstrated a dramatically enhanced immune response in mice against tumor growth and infection. The PIC vaccine bypasses key steps in the normal chain of events leading to immune response, directly targeting the cellular switch to muster a potent attack on foreign proteins.
Researchers at Advanced Cell Technology successfully reversed the aging process in cells, potentially leading to treatments for age-related diseases. The breakthrough involves using cloning technology to reset the cellular clock, allowing cells to divide indefinitely.
A study published in Science demonstrates the utility of ARIAD's RAPID technology, which allows for rapid and regulated delivery of therapeutic proteins. Human insulin was successfully delivered to diabetic mice via this method, correcting blood sugar levels within minutes.
The Choices and Challenges public forum project at Virginia Tech explores the humanistic components of science and technology, covering topics from genetic engineering to space technologies. The series has received national recognition, including two national awards, for its innovative approach to promoting dialogue between science, so...
A new method enables cheap and simple manufacture of customized DNA chips, revolutionizing genetic analysis and research. This technology can help diagnose genetic diseases and accelerate drug discovery, while reducing production costs.
The Wistar Institute's Recombinant Protein and Structure Evaluation Center has been admitted to the Ben Franklin Technology PArtners' Center of Excellence Network Program for the second consecutive year. The center provides services to small and medium-sized biotechnology and pharmaceutical companies, specializing in baculovirus expres...
A new bio-tech can remove up to half of impurities from crude oil, improving its physical and chemical properties. This breakthrough technology has the potential to make heavy crudes usable for clean-burning fuel, addressing the dwindling supply of lighter grades.
A breakthrough in taxol production has been made by Cytoclonal Pharmaceutics Inc. and MSU, moving the technology closer to manufacture and use. The sublicense agreement with Bristol-Myers Squibb aims to develop microbial fermentation of taxol, a renewable source for the potent drug.
A panel of leading research chemists will discuss new ways to fight disease, gene mapping and sequencing's impact on chemistry and medicine, and improving standard living through chemistry. Technologies like buckytube fibers and nanomaterials will also be explored.
The symposium will focus on functional genomics, gene delivery, bioinformatics, and therapeutic strategies for complex diseases. The event features renowned speakers discussing transplantation strategies and improvements in recovery after central nervous system injury.
UNESCO has issued a declaration stating that human cloning is unacceptable, citing ethical concerns and the preservation of humanity's infinite diversity. The organization's director-general has called for a world commission on ethics and science to tackle issues related to scientific developments beyond genetics.