A study published in the Journal of Thoracic Oncology found that VeriStrat can predict response to erlotinib, but does not provide a survival benefit. The test showed a significant difference in median survival between good and poor responders, with good responders experiencing longer survival on erlotinib.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateOct 15, 2012
A study published in the Journal of Thoracic Oncology found that fit elderly patients with non-small cell lung cancer can benefit from salvage targeted therapy without increased toxicity. The study analyzed data from 255 patients and showed no difference in response rates or progression-free survival between age groups.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateOct 15, 2012
Scientists at the University of York have discovered a protein called Ciz1 that is present in lung cancers, even in early stages. A simple blood test using this protein could help diagnose lung cancer without invasive procedures.
SourceUniversity of York·JournalProceedings of the National Academy of Sciences·DateOct 15, 2012
A study analyzing the International Mesothelioma Interest Group (IMIG) staging system for malignant pleural mesothelioma (MPM) reveals areas for potential revision. The current system distinguishes among T and N categories, but qualitative T descriptors may not be applicable to clinical staging.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateOct 15, 2012
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
A variant in the NFKB1 gene has been associated with a 44% reduced risk of lung cancer, according to a new analysis of 378 patients and 450 healthy controls. The study suggests that inflammation may play a role in lung cancer development.
A phase III trial shows that crizotinib is more effective than standard chemotherapy in response rates and progression-free survival, with improved quality of life. The study compared 347 patients with previously treated ALK-positive lung cancer and found significant benefits for those on the crizotinib arm.
SourceEuropean Society for Medical Oncology·JournalAnnals of Oncology·DateSep 30, 2012
Several new first-in-human studies for drugs targeting a range of cancers have shown promising results, including the development of MEK-, MET- and HSP90 inhibitors as well as immunotherapeutic strategies. Studies have demonstrated significant activity in ALK-positive lung cancer resistant to crizotinib and other targeted therapies.
SourceEuropean Society for Medical Oncology·JournalAnnals of Oncology·DateSep 30, 2012
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A post-hoc analysis of the phase III MISSION trial suggests that patients with EGFR-mutant tumors may benefit from sorafenib, which showed improved progression-free survival and disease control rates. In contrast, median overall survival was similar between treatment groups.
SourceEuropean Society for Medical Oncology·JournalAnnals of Oncology·DateSep 29, 2012
A blood test developed by Kansas State University researchers can accurately detect the beginning stages of breast and non-small cell lung cancer. The test works by detecting increased enzyme activity in the body, with a 95% success rate in detecting cancer in participants.
Researchers found that genetic diversity in natural killer cells contributes to lung cancer susceptibility. In mice, manipulating the immune system can significantly block tumor growth. The study suggests a key role for natural killer cells in lung cancer, potentially offering new targets for therapy.
SourceWashU Medicine·JournalCancer Research·DateSep 21, 2012
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Recent breast cancer research at ESMO 2012 emphasizes the importance of avoiding weight gain after treatment to reduce recurrence risk. Additionally, studies focus on the correlation between body mass index and prognosis, as well as lung cancer in never-smoking women, highlighting hormonal factors and high incidence of EGFR mutation.
SourceEuropean Society for Medical Oncology·JournalAnnals of Oncology·DateSep 17, 2012
A pilot study found that breath testing can accurately discriminate between benign and malignant pulmonary nodules. The technique, using volatile organic compounds and chemical nanoarrays, identified 53 malignant and 19 benign nodules with high accuracy.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateSep 15, 2012
Two new studies have identified novel genes and patterns of mutations involved in lung cancer, with significant differences found between smokers and non-smokers. These findings could lead to targeted therapies to improve survival rates and outcomes for lung cancer patients.
Crizotinib successfully shrinks tumors in patients with anaplastic lymphoma receptor tyrosine kinase (ALK) positive non-small cell lung cancer. The treatment showed a high overall response rate of 60% and improved median progression-free survival.
SourceAmerican Society for Radiation Oncology·JournalJournal of Thoracic Oncology·DateSep 6, 2012
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Patients with stage I non-small cell lung cancer (NSCLC) who received radiation therapy had an increased median survival of 21 months compared to 16 months. The percentage of patients not receiving treatment declined from 20 percent to 16 percent between 1999-2003 and 2004-2008.
SourceAmerican Society for Radiation Oncology·JournalJournal of Thoracic Oncology·DateSep 6, 2012
Researchers found that adding bavituximab to docetaxel chemotherapy improves response rates, progression-free survival, and overall survival in late-stage non-squamous, non-small cell lung cancer (NS-NSCLC) patients. The study showed a doubling of the overall response rate compared to the control arm.
SourceAmerican Society for Radiation Oncology·JournalJournal of Thoracic Oncology·DateSep 6, 2012
A study of 168 Stage III NSCLC patients found that married women had the best three-year survival rate of 46 percent, while single men had the worst rate of 3 percent. Married patients generally had improved survival rates compared to single patients, with 33 percent vs. 10 percent.
SourceAmerican Society for Radiation Oncology·JournalJournal of Thoracic Oncology·DateSep 6, 2012
Researchers found that standard chemotherapy with paclitaxel, carboplatin, and bevacizumab is equally effective as an experimental regimen in treating advanced non-squamous non-small cell lung cancer. The study suggests that both regimens are tolerable but have different toxicities.
SourceAmerican Society for Radiation Oncology·JournalJournal of Thoracic Oncology·DateSep 6, 2012
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
A study of 14,829 Hispanic lung cancer patients from the California Cancer Registry found that foreign-born Hispanics have an even lower risk of death due to improved socio-economic factors and neighborhood conditions. This contradicts the traditional 'Hispanic paradox' by highlighting the positive impact of social factors on survival.
SourceAmerican Society for Radiation Oncology·JournalJournal of Thoracic Oncology·DateSep 6, 2012
A recent study published in the University of Maryland Medical Center found that married lung cancer patients have a higher survival rate compared to single patients. The researchers believe that social support from spouses is a key factor contributing to improved survival rates for married lung cancer patients.
SourceUniversity of Maryland Medical Center·DateSep 6, 2012
The study found an increase in non-smokers developing lung cancer, particularly women, and a shift towards adenocarcinoma. Researchers attributed this change to improved diagnostic techniques and management of lung cancer.
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
A Phase I/II trial tests the safety and efficacy of PR610 in patients with advanced cancer. The study aims to deliver a targeted approach, activating the compound in tissues with low oxygen levels characteristic of many cancers.
SourceThe Translational Genomics Research Institute·DateAug 29, 2012
A recent University of Colorado Cancer Center case study found a patient with ALK+ lung cancer who tested negative for the EML4-ALK fusion gene using the FDA-approved FISH assay, yet showed dramatic response to crizotinib. Next-gen sequencing revealed genetic shards that may have avoided detection by the test.
SourceUniversity of Colorado Anschutz Medical Campus·JournalJournal of Thoracic Oncology·DateAug 28, 2012
A lung cancer risk prediction model developed at the University of Liverpool has been shown to be a viable tool for selecting high-risk individuals. The model was tested in international datasets and found to be more effective than smoking duration or family history alone in predicting individuals at risk.
SourceUniversity of Liverpool·JournalAnnals of Internal Medicine·DateAug 20, 2012
Recent studies suggest that colonoscopy-related factors are more predictive of colorectal cancer risk than polyp characteristics. High levels of lead exposure also pose significant health risks, even at low blood lead levels. Meanwhile, a new lung cancer screening model shows high accuracy in identifying patients who will benefit from ...
SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateAug 20, 2012
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Researchers have identified an experimental drug, GSIs, that blocks Notch and prevents lung cancer growth in mice without treatment-related side effects. This discovery brings new clues for the treatment of lung cancer and is being tested in co-clinical trials.
SourceCentro Nacional de Investigaciones Oncológicas (CNIO)·JournalCancer Cell·DateAug 13, 2012
Researchers have identified how EPHA3 gene mutations may promote lung cancer. The study found that loss of the gene diminishes its tumor-suppressive effect, potentially sparking tumor growth. The findings suggest that therapies targeting a downstream pathway may be beneficial for tumors with mutant EPHA3.
SourceVanderbilt University Medical Center·JournalJNCI Journal of the National Cancer Institute·DateJul 30, 2012
Scientists investigate the use of novel AKT inhibitor MK-2206 in combination with erlotinib as a second-line defense for patients with non-small cell lung cancer (NSCLC) who have developed resistance to erlotinib. A Phase II trial has shown promising initial results.
SourceInternational Association for the Study of Lung Cancer·DateJul 25, 2012
Researchers from the British Columbia Cancer Research Center analyzed lung tumors exposed to arsenic, highlighting genetic and epigenetic changes driving carcinogenesis. These findings may help prevent arsenic-related cancer in regions with low exposure levels.
SourceInternational Association for the Study of Lung Cancer·DateJul 25, 2012
Researchers are developing a multiple marker test in peripheral blood to detect lung cancer, promising an earlier diagnosis. The test discriminated between healthy donors and patients with non-small cell lung cancer (NSCLC) with high accuracy.
SourceInternational Association for the Study of Lung Cancer·DateJul 25, 2012
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Chronic obstructive pulmonary disease (COPD) increases lung cancer risk through a novel mechanism involving long-term oxygen depletion and HIF-2a tumor growth signaling. COPD-induced signals may be susceptible to prevention or treatment with VEGFR-2 and EGFR inhibitors.
SourceUniversity of Colorado Anschutz Medical Campus·JournalCancer Prevention Research·DateJul 24, 2012
A new rehabilitation program developed by Michigan State University's Amy Hoffman uses the Nintendo Wii-Fit Plus to promote light-intensity walking and balance exercises. The program has shown excellent improvement in reducing cancer-related fatigue levels over time.
Researchers at Kaiser Permanente Southern California identified 7,112 patients with lung nodules using existing medical records. They developed an automated method that classifies nodules with 96% sensitivity and 86% specificity compared to clinician review.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateJul 15, 2012
Researchers at Mayo Clinic found that early-stage lung cancer cells use a biological process called epithelial-mesenchymal transition (EMT) to bypass growth controls and enable uncontrolled growth. This discovery offers new clues for a potential approach to treating lung and possibly other cancers as early as possible.
SourceMayo Clinic·JournalScience Translational Medicine·DateJul 11, 2012
Researchers identify microRNA-320a as a key regulator of glycolysis in tumors and unused muscles, potentially leading to new treatments for lung cancer and improving ventilator recovery. This discovery offers a significant therapeutic leap for numerous diseases and health conditions.
SourceFederation of American Societies for Experimental Biology·JournalThe FASEB Journal·DateJul 6, 2012
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers at UCSF have discovered that a human protein called AXL drives resistance to Tarceva, which suggests that blocking the protein may prevent resistance to the cancer drug. This discovery may lead to better treatments involving precision medicines that combine Tarceva with new drugs designed to block AXL.
SourceUniversity of California - San Francisco·JournalNature Genetics·DateJul 1, 2012
Researchers discovered that combining EGFR inhibitors with Wnt pathway inhibition can improve the durability of lung cancer remission. The Wnt pathway allows lung cancer cells to escape from EGFR-targeted therapy, but disrupting this pathway could lengthen the usefulness of existing treatments.
SourceUniversity of Colorado Anschutz Medical Campus·JournalCancer Research·DateJun 28, 2012
A new study reveals dramatic differences in lung cancer death rates among women born between 1930s and 1970s in various US states. California shows a decline in lung cancer death rates, while many southern states experience an increase, highlighting the need for stronger tobacco control policies.
SourceAmerican Cancer Society·JournalJournal of Clinical Oncology·DateJun 25, 2012
Researchers are enrolling patients to detect lung cancer through volatile organic compounds in exhaled breath. Early detection can significantly improve treatment options and survival rates.
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
The American Association for Thoracic Surgery task force recommends expanded lung cancer screening guidelines using low-dose computed tomography (LDCT) for high-risk individuals. The new guidelines increase the recommended age range to 79 and expand eligibility to smokers and former smokers with specific risk factors.
SourceBrigham and Women's Hospital·JournalJournal of Thoracic and Cardiovascular Surgery·DateJun 21, 2012
A study published in the Journal of Thoracic Oncology found that stereotactic ablative radiotherapy is an effective treatment option for elderly patients with stage I non-small cell lung cancer. The treatment did not negatively impact health-related quality of life, and functional and symptom outcomes remained stable after two years.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateJun 15, 2012
A study published by the International Association for the Study of Lung Cancer found that high-volume hospitals and thoracic surgeons have lower mortality rates compared to general surgeons. The researchers recommend a national audit program to evaluate institutions based on quality parameters, including hospital volume.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateJun 15, 2012
Researchers discovered a new mechanism that promotes lung cancer growth and survival by regulating autophagy, a complex process initiated under stressful conditions. The protein BI-1 was found to protect lung cancer cells and suppress tumor growth by modulating intracellular signals.
SourceVirginia Commonwealth University·JournalGenes & Development·DateJun 15, 2012
Researchers found that perioperative chemotherapy improved overall survival in patients with limited large cell neuroendocrine tumors or small-cell lung cancer after surgery. The study of 74 patients showed a significant difference in overall survival between those who received chemotherapy and those who did not.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateJun 15, 2012
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
Researchers at UNC Health Care identify a key genetic switch that determines melanoma's ability to spread. Inactivating the LKB1 gene causes non-aggressive cells to become highly metastatic.
SourceUniversity of North Carolina Health Care·JournalCancer Cell·DateJun 11, 2012
Researchers discovered that ADAM28 inhibits VWF-mediated apoptosis in cancer cells, leading to increased lung metastases. Inhibition of ADAM28 expression or activity significantly reduced lung metastases and increased cancer cell apoptosis.
SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateJun 8, 2012
LDK378 shows encouraging activity in patients with ALK+ non-small cell lung cancer, including those who no longer respond to crizotinib. The compound is well-tolerated and its optimal dose is being further tested.
A novel compound has shown significant benefits in patients with KRAS-mutant non-small cell lung cancer, improving treatment response and survival times. The study's findings suggest a potential effective treatment for this common subtype of lung cancer.
Researchers created a new anti-cancer drug named BP-1-102 that targets the Stat3 protein, which triggers cancer development in various types. The drug remains effective even when administered orally, unlike most current treatments requiring intravenous injection.
SourceUniversity of Hawaii Cancer Center·JournalProceedings of the National Academy of Sciences·DateMay 21, 2012
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
A new study found that active tuberculosis is an independent predictor of lung cancer death in the elderly. The research analyzed data from 61,239 subjects aged 65 years or older and found a significant association between tuberculosis and lung cancer mortality.
A systematic review found that low-dose computerized tomography (LDCT) screening can reduce lung cancer mortality rates among high-risk individuals. The study analyzed 8 randomized controlled trials and 13 cohort studies, with the National Lung Screening Trial demonstrating a significant benefit. However, potential harms of LDCT screen...
Researchers found that tenasin-C gene expression and nodule size can predict lung cancer with improved accuracy. The study used bronchoscopic microsampling to collect fluid from lung nodules, showing promise for a less invasive diagnostic technique.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateMay 15, 2012
A recent study found VATS resection in CT-screened high-risk Danish population yielded higher incidence of early stage lung cancer. The study detected 68 lung cancers in the screened group versus 24 in the unscreened group, with 51 patients suitable for surgery and 84% undergoing VATS.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateMay 15, 2012
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
A recent study suggests a positive correlation between tumor size and chemotherapy efficacy in surgically resected patients with node-negative non-small cell lung cancer. The study found no clear threshold for tumor size that correlated with a benefit from chemotherapy.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateMay 15, 2012
A UNC-led team discovers that lung cancer molecular subtypes correlate with distinct genetic alterations and patient response to therapy. The study refines their previous report on three molecular subtypes of non-small cell lung cancer, suggesting new avenues for targeted treatment.
SourceUniversity of North Carolina Health Care·JournalPLOS ONE·DateMay 11, 2012
Researchers combine a blood test with CT imaging to screen for cancer, aiming to detect early-stage lung cancers while reducing biopsies and operations. The trial may improve survival rates and reduce the toll of lung cancer on patients.
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
A study of over 20,000 older patients with non-small-cell lung cancer found that younger patients were more likely to receive treatment than their older counterparts. The research suggests that age alone is not a reliable indicator for cancer treatment decisions, and other health factors should be considered.
SourceUniversity of California - San Francisco·JournalJournal of Clinical Oncology·DateMay 2, 2012
A study published in JNCI found a strong association between genetic variants rs1051730-rs16969968 and objective measures of tobacco exposure, indicating that lung cancer risk is largely mediated by level of tobacco exposure. The research used data from six independent studies to analyze self-reported cigarette consumption and plasma o...
SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateApr 25, 2012
Researchers at Mayo Clinic have identified a single gene, MMP-10, that promotes the development and spread of lung cancer. This discovery suggests that targeting this gene may be an effective way to treat non-small cell lung cancer.
A new analysis found that Hispanic lung cancer patients have a 15% lower risk of dying compared to white patients, with black patients slightly more likely to die. The study also identified higher frequencies of less serious lung cancer types in Hispanics, which may be linked to genetic or environmental factors.