Researchers at Boston University School of Medicine have discovered a regulatory molecule, miR-4423, that is less abundant in people with lung cancer and inhibits lung cancer cell growth. This molecule may aid in diagnosing lung cancer in earlier stages and treating the disease when at healthy levels.
SourceBoston University School of Medicine·JournalProceedings of the National Academy of Sciences·DateOct 25, 2013
Researchers at Penn Medicine found that focusing on factors like hope, randomization, and altruism can increase patient willingness to participate in clinical trials for malignant pleural mesothelioma. The study showed a significant increase in participation rates when physicians spent more time discussing these factors with patients.
SourceUniversity of Pennsylvania School of Medicine·DateOct 23, 2013
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
Researchers found metformin as an effective radiosensitizer for treating stage III non-small cell lung cancer, improving local control and overall survival. The study suggests combining metformin with chemotherapy and radiation therapy may be a promising treatment approach.
SourceUniversity of Pennsylvania School of Medicine·DateOct 23, 2013
As people age, gene mutations and epigenetic changes accumulate, increasing cancer risk. Researchers will examine the role of epigenetics in lung cancer development, seeking new biomarkers to predict cancer risk.
PF-06463922, a new investigational drug, has shown potent activity against the ALK protein kinase and its mutants, including those resistant to crizotinib. This offers a potential treatment option for patients with lung cancer harboring ALK gene abnormalities.
SourceAmerican Association for Cancer Research·DateOct 20, 2013
Researchers discovered 127 genes that appear to drive the development of a range of tumors in the body across 12 major cancer types. The study found common links among genes in different cancers, as well as mutations exclusive to particular cancer types.
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
The International Association for the Study of Lung Cancer (IASLC) awarded five people Advocacy Travel Awards to support their attendance at the 2013 World Conference on Lung Cancer in Sydney. The awards provide conference registration, accommodations, a free IASLC Membership, and a travel stipend.
SourceInternational Association for the Study of Lung Cancer·DateOct 16, 2013
A study suggests that Indi's blood test can accurately distinguish between benign lung nodules and early-stage lung cancer by detecting a specific combination of proteins in the blood. The test, powered by advanced protein detection technology, has a 90% accuracy rate and could complement current clinical risk factors.
SourceIndi (Integrated Diagnostics)·JournalScience Translational Medicine·DateOct 16, 2013
PET scans can identify patients with more aggressive tumors, enabling intensified treatment for locally advanced lung cancer. The study found a strong correlation between radiation dose intensity and local control of the cancer.
SourceUniversity Hospitals Cleveland Medical Center·JournalJournal of Clinical Oncology·DateOct 7, 2013
A phase I clinical trial has shown that an anti-PD-L1 monoclonal antibody can produce striking responses in non-small cell lung cancer patients with metastatic disease who have failed to respond to previous chemotherapy. Smokers and former smokers are more likely to benefit from this treatment.
SourceECCO-the European CanCer Organisation·DateSep 29, 2013
Researchers at Ohio State University have discovered that high levels of microRNA-31 in primary tumor cells predict lymph node metastasis and poor survival in patients with non-small cell lung cancer. Low expression levels were associated with excellent survival.
SourceOhio State University Wexner Medical Center·JournalClinical Cancer Research·DateSep 24, 2013
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
The study found a significantly lower quality of life in patients who received high-dose radiation therapy (74 Gy) compared to those receiving standard dose (60 Gy). IMRT was associated with a lower decline in QOL compared to 3-D CRT, even a year after treatment.
SourceAmerican Society for Radiation Oncology·DateSep 23, 2013
UT Southwestern researchers discover that a protein overactivity sabotages cellular recycling, leading to heightened cancer growth and chemotherapy resistance. Autophagy inhibition may worsen chemotherapy outcomes for patients with specific cancer mutations, according to the study published in Cell.
SourceUT Southwestern Medical Center·JournalCell·DateSep 18, 2013
Researchers from RIKEN Center for Life Science Technologies identified a genetic mutation associated with improved survival rates in lung cancer patients who do not smoke. The mutation affects the NRF2 gene, which protects cells from oxidative stress.
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
A University of Colorado Cancer Center study found that current ALK-positive lung cancer criteria may miss patients who could benefit from crizotinib. The researchers suggest that doctors should re-evaluate borderline or atypical cases, potentially expanding treatment eligibility.
SourceUniversity of Colorado Anschutz Medical Campus·JournalCancer·DateSep 10, 2013
Researchers have developed a cheap and non-invasive breath test to diagnose lung cancer, which has been shown to correctly identify lung cancer patients with high sensitivity. The technique uses an electronic nose to detect volatile organic compounds in exhaled breath samples.
A new publication by the European Respiratory Society reveals that lung conditions account for 12.5% of EU deaths, with annual costs totaling at least 390 billion Euros. The White Book estimates direct and indirect costs due to lung diseases are around 400 billion Euros annually.
Researchers recommend accelerated radiotherapy as standard treatment for un-resected non-small cell lung cancer patients not receiving concurrent chemo-radiotherapy, citing its efficiency over current practice. However, cost-effectiveness of different modified schemes remains uncertain and requires further research.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateSep 4, 2013
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
A prospective cohort study of 81,697 racially diverse adults found that lung cancer survival between black and white patients was similar when demographic factors and smoking were controlled. The study aimed to address racial disparities in lung cancer survival rates.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateSep 4, 2013
A new clinical risk calculator software has been developed to accurately classify benign and malignant spots on lung scans of smokers. The software uses a prediction model that considers several factors, including size, age, family history, and location of the nodule, to predict the probability of cancer.
SourceTerry Fox Research Institute·JournalNew England Journal of Medicine·DateSep 4, 2013
A new set of evidence-based guidelines recommend lung cancer screening for high-risk populations in Ontario using low-dose computed tomography (LDCT). The guidelines suggest annual screening for two years, followed by biennial screenings until a negative result is obtained. The recommended parameters for LDCT include 120 to 140 kVp and...
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateSep 4, 2013
Researchers found that Notch 1 is required for initial tumor growth and survival of cancer cells. Disabling Notch 1 leads to increased cancer cell death through increased p53 stability.
SourceScripps Research Institute·JournalCancer Research·DateAug 29, 2013
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
A study led by UT Southwestern Medical Center researchers found that total tumor measurements greater than 3 inches predict shorter survival times in advanced lung cancer patients. Patients with larger tumors live an average of 9.5 months, compared to 12.6 months for those with smaller tumors.
SourceUT Southwestern Medical Center·JournalBritish Journal of Cancer·DateAug 19, 2013
Researchers at Moffitt Cancer Center identified four genetic variants associated with increased risk of death in non-small cell lung cancer patients. These variants also indicate a greater risk of death if treatment plans include surgery without chemotherapy compared to those with chemotherapy following surgery.
SourceH. Lee Moffitt Cancer Center & Research Institute·JournalCarcinogenesis·DateAug 9, 2013
Researchers found that a specific pattern in tumor pathology is strongly associated with cancer recurrence. Patients with this pattern are more likely to benefit from lobectomy and have a 75% lower risk of recurrence. The study may lead to new technology to precisely identify tumors with this pattern before surgery.
SourceMemorial Sloan Kettering Cancer Center·JournalJNCI Journal of the National Cancer Institute·DateAug 7, 2013
Researchers at Fred Hutchinson Cancer Center are pioneering a new approach to harness the power of the adaptive immune system to control cancer. They are using high-throughput technology and large-scale data mining to identify potential immune targets and verify their immunogenicity.
Screening asymptomatic high-risk adults for lung cancer using low-dose computed tomography (LDCT) may significantly reduce mortality, according to a systematic review. The US Preventive Services Task Force reviewed 67 articles and found that LDCT screening can detect lung cancer at an earlier stage, leading to lower mortality rates.
SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateJul 29, 2013
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Researchers found that obese patients initially had superior outcomes in terms of overall survival compared to normal-weight and overweight patients. However, their risk of death from any cause significantly increased once they were on the study longer than 16 months, indicating a limited time benefit of obesity in lung cancer patients.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateJul 25, 2013
Researchers in Canada found that funding from the pharmaceutical industry significantly decreased EGFR mutation testing after it was discontinued. The Canadian healthcare system lacked resources for implementing a national policy, leading to a substantial drop in test requests.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateJul 25, 2013
Researchers have identified Ephrin B2 as a promising target for treating malignant pleural mesothelioma, a rare and aggressive form of lung cancer. The study found that EPHB2 is significantly overexpressed in tumor tissue compared to normal peritoneum, suggesting its potential as a biomarker for early diagnosis and treatment.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateJul 25, 2013
Researchers at Moffitt Cancer Center discovered a gene expression signature that may lead to new immune therapies for lung cancer patients. High levels of NF-κB in lung cancer tumors can act as a suppressor, boosting the immune system to eliminate cancerous cells.
SourceH. Lee Moffitt Cancer Center & Research Institute·JournalJournal of Clinical Investigation·DateJul 22, 2013
A study by Weill Cornell Medicine found that even healthy-looking smokers have damaged airway cells with characteristics similar to those in aggressive lung cancer. The researchers discovered that these cells express human embryonic stem cell genes, which are normally only active in developing embryos.
SourceWeill Cornell Medicine·JournalStem Cells·DateJul 16, 2013
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A European-wide study found that prolonged exposure to particulate air pollution increases the risk of lung cancer, particularly adenocarcinoma, at concentrations below EU limit values. The analysis of 17 cohort studies involved over 313,000 people and found a strong association between air pollution and lung cancer risk.
SourceThe Lancet_DELETED·JournalThe Lancet Oncology·DateJul 9, 2013
The foundation awarded six new Clinical Investigators, including Omar Abdel-Wahab and Himisha Beltran, for their cancer research programs. The recipients will receive $450,000 each, while three others received Continuation Grants worth $300,000 to support ongoing research.
SourceDamon Runyon Cancer Research Foundation·DateJul 1, 2013
Researchers have developed two new methodologies to determine ALK status in non–small-cell lung cancer (NSCLC) patients. The first method improves IHC assay sensitivity using a novel hapten and tyramide amplification, detecting low levels of ALK protein expression. The second method combines brightfield IHC with in situ hybridization f...
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateJul 1, 2013
Researchers developed a highly accurate method to detect ALK-rearranged non-small cell lung cancer using immunocytochemistry. The study found that this method had high sensitivity and specificity, making it suitable for prescreening NSCLC patients.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateJul 1, 2013
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Anurag Singh, PhD, has received a $100,000 ALA Lung Cancer Discovery Grant to study targeted therapies for drug-resistant lung cancers. He aims to develop strategies to block KRAS protein function and improve treatment outcomes.
SourceBoston University School of Medicine·DateJul 1, 2013
A study of 582 patients with stage I non-small cell lung cancer (NSCLC) found SBRT to be safe and effective, with a three-year freedom from local progression rate of 79.6%. The biological effective dosage was the most significant factor influencing outcomes.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateJul 1, 2013
A recent study found that lung cancer in women who have never smoked is more frequently associated with EGFR mutations and estrogen receptor (ER) overexpression. The researchers observed a higher percentage of these genetic abnormalities in patients who had not previously smoked, suggesting potential new treatment targets for this group.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateJun 25, 2013
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Researchers evaluate immunohistochemistry for detecting ALK rearrangement in lung adenocarcinoma, finding it a reliable and cost-effective method. The study suggests that IHC can effectively detect ALK rearrangement and identify suitable candidates for targeted therapy.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateJun 25, 2013
Researchers at UT Dallas discovered that lung cancer cells consume more oxygen and synthesize a critical chemical called heme, which can be exploited to inhibit cancer growth. Inhibiting heme synthesis affects lung cancer cells' ability to proliferate and migrate.
SourceUniversity of Texas at Dallas·JournalPLOS ONE·DateJun 18, 2013
A study by St. Jude Children's Research Hospital found that 98% of childhood cancer survivors have at least one chronic health condition, with 80% developing a life-threatening condition by age 45. Regular medical checkups and healthy lifestyle choices can help mitigate risk.
SourceSt. Jude Children's Research Hospital·JournalJAMA·DateJun 11, 2013
Dr. Matt Huentelman and Dr. Glen Weiss are among the 40 Under 40 honorees recognized by the Phoenix Business Journal for their contributions to genomic research, including TGen's MindCrowd project and lung cancer studies. The recognition highlights the institute's advancements in understanding human genetics and developing new treatments.
SourceThe Translational Genomics Research Institute·DateJun 5, 2013
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Researchers have discovered a new oncogene, NTRK1, that drives a subset of lung cancers. A novel targeted treatment approach has been proposed, with preclinical studies showing effective silencing of mutated NTRK1 genes using specific compounds.
SourceUniversity of Colorado Anschutz Medical Campus·DateJun 3, 2013
Researchers have discovered a new oncogene, RET rearrangement, which is present in 15.7% of lung adenocarcinoma patients and may be targeted with existing tyrosine-kinase inhibitors. This finding presents a promising treatment option for patients with this specific mutation.
SourceUniversity of Colorado Anschutz Medical Campus·DateJun 2, 2013
Researchers found that crizotinib boosts median disease progression time to 7.7 months, compared to 3 months with standard chemotherapy, in patients with non-small cell lung cancer harboring an abnormal ALK gene.
SourceDana-Farber Cancer Institute·JournalNew England Journal of Medicine·DateJun 1, 2013
Two MGH-led studies show crizotinib is superior to chemotherapy for advanced ALK-positive non-small cell lung cancer, with over double the progression-free survival. A second study reports the first crizotinib resistance in a ROS1-positive lung tumor, revealing the mechanism underlying that resistance.
SourceMassachusetts General Hospital·JournalNew England Journal of Medicine·DateJun 1, 2013
Researchers at Fox Chase Cancer Center are conducting further tests on the drug nivolumab, a monoclonal antibody that targets the immune system's response to cancer. The therapy appears to produce largely manageable side effects and has shown potential in treating tumors more effectively than current treatments.
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Sarcomatoid lung carcinomas are rare and aggressive diseases resistant to chemotherapy. Researchers found higher levels of programmed death ligand-1 (PD-L1) in these tumors, which may lead to the use of anti-PD-1/PD-L1 targeted therapies. This discovery supports potential novel immunotherapy approaches for this difficult-to-treat disease.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateMay 28, 2013
Researchers have identified two ruthenium-based complexes that target cancer cells more effectively and are less toxic than current chemotherapies. The complexes, which seem to target cells in hypoxic states, could complement widely used platinum-based therapies like cisplatin.
SourceUniversity of Texas at Arlington·JournalMolecular Cancer Therapeutics·DateMay 28, 2013
A new LSUHSC paper has been selected as the Best Paper of the Year by the National Cancer Registrars Association for its innovative evaluation of cancer stages. The study found that lung and prostate cancers had the highest percentages of unknown stages, with non-hospital reporting sources being a key predictor.
SourceLouisiana State University Health Sciences Center·DateMay 28, 2013
Sky & Telescope Pocket Sky Atlas, 2nd Edition
Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
A recent study published in the Journal of Thoracic Oncology found that digital chest tomosynthesis (DT) holds promise as a first-line lung cancer screening tool. DT improved sensitivity in detecting lung nodules compared to conventional chest radiography, while providing lower costs and radiation dosages.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateMay 28, 2013
Researchers have developed a new drug delivery system that uses nanoparticles and siRNA to target lung cancer cells, eliminating resistance and reducing systemic damage. In laboratory tests, the system showed significant improvement in treating lung tumors, with nearly 83% of the drug delivered directly to the lungs.
SourceOregon State University·JournalJournal of Controlled Release·DateMay 22, 2013
A new study confirms low-dose computed tomography (LDCT) detects more early-stage lung cancers than chest X-ray (CXR), supporting a 20% reduction in mortality. Compliant imaging facilities performed 98.5% of studies within protocol specifications.
SourceAmerican College of Radiology·JournalNew England Journal of Medicine·DateMay 22, 2013
A new study shows that minimal dose computed tomography (MnDCT) is more sensitive than conventional chest X-rays in detecting new or recurrent lung cancer, while delivering a similar amount of radiation. The study found that MnDCT detected 94% of recurrent cancers compared to 21%, allowing for earlier treatment and longer survival rates.
SourceAmerican Association for Thoracic Surgery·DateMay 6, 2013
A new portable and real-time airborne asbestos detector has been developed using a laser-based light scattering technique. The device can identify asbestos fibers on-site, reducing the risk of lung cancers such as mesothelioma.
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers found that a combination of chemoradiation therapy and surgery improves overall survival in stage 3 non-small cell lung cancer patients. Five-year survival rates were twice as high for those who received chemoradiation followed by surgery compared to those who only had chemoradiation.
SourceUniversity of Illinois Chicago·JournalJournal of Thoracic Oncology·DateApr 30, 2013
Researchers discovered that abnormal histone protein modification impairs DNA repair machinery, leading to a potential new way of detecting colorectal cancers. The study, published in Cell, reveals a novel mechanism explaining the root cause of some forms of colorectal cancers.
A retrospective study suggests that patients with lung cancer carrying specific HER2 mutations may experience tumor shrinkage and delayed disease progression when treated with anti-HER2 drugs. The study found 1.7% of NSCLC patients in Europe had these rare mutations, which can lead to continuous activation of the HER2 protein.
SourceAmerican Society of Clinical Oncology·JournalJournal of Clinical Oncology·DateApr 22, 2013
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
A recent study published in the Journal of Thoracic Oncology found that higher primary care provider density is associated with lower lung cancer mortality rates, particularly among white populations. The researchers suggest that interventions aimed at primary care providers may deserve more investigation to improve access to cancer care.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateApr 22, 2013