A new study from Australia found that decreased sexual activity and desire in older men may be a cause, not an effect, of low circulating testosterone levels. Over two years, men with declining serum testosterone were more likely to experience a significant decrease in their sexual activity.
Research highlights benefits of screening, identifying 5.8 million men with unknown heart risk factors over 20 years and avoiding 1.1 million cardiovascular events, saving $28 billion.
Research suggests that patients with erectile dysfunction who follow a Mediterranean diet have less vascular and cardiac damage, reducing their risk of heart attack and stroke. A lower Med-Diet Score correlated with worse vascular and heart function, including increased intima-media thickness and aortic stiffness.
Men with early atherosclerotic plaque development and arterial stiffness are more likely to develop erectile dysfunction. Researchers found that coronary artery calcium scores were the strongest association to erectile dysfunction, followed by carotid intima-media thickness.
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Research identifies DNA copy number variation (CNV) as the genetic cause behind two male pseudo-hermaphrodite horses' sex identity. The study provides the first hints about likely molecular causes and involvement of CNVs in equine disorders, with potential biomedical significance beyond horse racing.
A study found that autistic males have lower levels of estrogen receptors and aromatase, an enzyme converting testosterone to estradiol. This could lead to increased testosterone levels, potentially contributing to the disorder's prevalence in men. The findings suggest a possible reason for the gender bias in autism diagnosis.
A recent study by York University researchers found that adults with autism are at a higher risk of sexual victimization due to a lack of sex education. The study highlights the importance of improving interventions that focus on sexual knowledge and skill building.
A new study published in the American Journal of Preventive Medicine found that returning National Guard soldiers are more likely to develop a drinking problem if faced with civilian life setbacks. The study highlights the important role civilian life and stress play in cases of alcohol use disorder among National Guard soldiers.
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Researchers at Columbia University's Mailman School of Public Health found that nearly 14% of reserve soldiers returning from deployment experience alcohol abuse, almost double the civilian population rate. The study highlights the important role civilian life and stress play in cases of alcohol use disorder among National Guard members.
A working group recommends removing sexual orientation-related disorders from the ICD to improve healthcare access for LGBTQ individuals. The move could lead to improved treatment and reduced risk of mistreatment, such as conversion therapy.
Researchers analyzed 763 South African men who frequent public drinking venues, finding nearly two-thirds with Alcohol Use Disorder (AUD), associated with increased HIV risk. The study highlights the need for integrated interventions targeting both alcohol and HIV-risk behaviors.
A new study finds that most men with gout have severe erectile dysfunction, highlighting the importance of screening for this condition. The study suggests that all men with gout should be routinely screened for erectile dysfunction to detect possible silent coronary artery disease.
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Researchers at UNIGE identified a mutation in the HHAT gene, which plays a key role in embryonic development and affects sexual development, growth, and skeletal development. The study provides new insights into Hedgehog signaling and has implications for genetic testing and treatment of patients with disorders of sex development.
Researchers used multiphoton microscopy to visualize podocyte calcium dynamics in response to glomerular injury, finding a robust calcium wave that spread throughout cells. Additionally, a mutation in the steroidogenic factor 1 (SF-1) gene was identified as causing asplenia and disorder of sexual development in a pediatric patient.
A new Rutgers study suggests that statin medication can not only lower cholesterol and reduce the risk of heart attack and stroke but also improve a man's erectile function. The researchers found that older men with poor cardiovascular health, diabetes, or metabolic syndrome often experience erectile dysfunction.
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Researchers found that statins significantly improve erectile function in men with both high cholesterol and erectile dysfunction. Erectile function scores increased by 24.3% in men taking statins, outperforming lifestyle modifications. The study suggests that statins may help improve blood flow to the penis and reduce symptoms of ED.
A new study published in the Journal of Sexual Medicine found that 29% of men with erectile dysfunction were able to reverse their condition through lifestyle changes. The study highlights the importance of addressing risk factors such as obesity, alcohol intake, and sleep disorders to improve sexual health.
Research reveals that women with hypoactive sexual desire disorder have distinct brain blood flow patterns, particularly in regions involved in attention, emotion, and memory. This study provides novel insights into the physiological basis of sexual dysfunction and may lead to the development of new therapies.
A recent study published in The Journal of Sexual Medicine found that nearly half of young men with newly-diagnosed erectile dysfunction (ED) experience severe ED. Younger patients had lower body mass index, higher testosterone levels, and fewer medical conditions compared to older patients.
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A new study analyzed 6.2 million patients and found that 74.6% of men with erectile dysfunction remained untreated, highlighting the need for improved treatment access and awareness. The study also showed that treatment frequency varied by co-morbidities, with hypogonadism being a key factor in treatment usage.
Researchers found that nano-hMSCs can promote cavernous neuronal regeneration and repair erectile dysfunction. The study revealed that transplantation of nano-hMSCs increased the expression levels of cavernous neuronal, endothelial, and smooth muscle makers.
A major new study has found that men with erectile dysfunction are at higher risk of hospital admission for heart disease and premature death. The research, which examined data from over 95,000 men, also showed a direct link between the severity of erection problems and the risk of cardiovascular events.
Researchers at the University of Michigan are developing a decision-making aid to support parents in making informed decisions about their child's diagnosis and treatment. The guide will educate families about sex development, genetic testing, and possible consequences of decisions on their child and entire family.
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A study published in the Journal of Sexual Medicine found that men with severe periodontal disease are three times more likely to suffer from erection problems. The researchers compared 80 men aged 30 to 40 with erectile dysfunction to a control group of 82 men without erection problems.
A UCLA-led team of experts found the proposed criteria to be reliable and valid in helping mental health professionals diagnose hypersexual disorder. The study accurately classified 88% of patients as having the disorder, with significant consequences including job loss, relationship end, and emotional distress.
A study found that nearly half of males and 30% of females had psychiatric disorders five years after detention, highlighting the long-term impact of juvenile incarceration on mental health. Substance use disorders were the most common, with males having a higher risk than females.
A study has identified 12 genetic markers associated with erectile dysfunction in prostate cancer patients treated with radiation. The findings may help clinicians predict complications and develop therapies to alleviate side effects.
Scientists have discovered a complex positive feedback loop in penile nerves that triggers waves of nitric oxide to keep the penis erect. This process, which involves phosphorylation, enables the sustained release of nitric oxide and maintains erection.
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Experts say that younger men with erectile dysfunction are twice as likely to develop cardiovascular disease. A thorough non-invasive cardiovascular disease evaluation is recommended for all men diagnosed with organic ED due to low testosterone levels and other risk factors.
A multi-center study found that patients who undergo complete kidney removal are 3.5 times more likely to develop erectile dysfunction compared to those with kidney reconstruction. Researchers suggest that total kidney removal may also increase the risk of metabolic diseases and decrease quality of life.
A study by UK researchers found parents of children with genital ambiguity experience shock, anxiety and a need to protect their child. The parents sought harmony between their child's ambiguity and the sex they raised them as.
A meta-analysis of six randomized controlled trials found that treating cardiovascular risk factors improves sexual function in men with erectile dysfunction, even when lifestyle interventions alone were used. The study suggests that addressing CV risk factors can have a positive impact on ED and overall quality of life.
Non-invasive prenatal tests using cell-free fetal DNA from mother's blood have high sensitivity and specificity for determining fetal sex. The study found that performance improves with later gestation, making this technology useful for early detection of fetuses at risk for sex-linked disorders.
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Researchers found a connection between erectile dysfunction and social networks shared by heterosexual men and their partners. Partner betweenness, where a male partner has weaker relationships with his confidants than his female partner, is linked to increased risk of ED.
A study published in JAMA Network found that women who experience gender-based violence have a higher lifetime prevalence of mental health disorders, including anxiety, mood disorder, and substance use disorder. The researchers also found that the association is particularly strong for exposure to multiple forms of GBV.
Researchers found that antioxidants may have significant value in addressing infertility issues, including erectile dysfunction. Antioxidants can help control free radicals that destroy nitric oxide, an agent that relaxes and dilates blood vessels.
A study published in Clinical Cardiology reveals that CRT significantly improves libido, erectile dysfunction, and sexual performance in men with chronic heart failure. The therapy improves functional capacity and ejection fraction, leading to better sexual health outcomes.
A study published in the Journal of Clinical Investigation has found that a brain gene called SOX3 can be activated to trigger male development in mice without a Y chromosome. This discovery has implications for understanding disorders of sexual development and may lead to new treatments.
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A study published in the American Journal of Human Genetics reveals a genetic alteration, MAP3K1, responsible for disorders of sex determination (DSD). The discovery provides insight into the cause of DSDs and contributes to better management, including the importance of removing gonads early to prevent cancer.
Teens with certain psychiatric diagnoses, such as bipolar disorder and externalizing disorders, are more likely to engage in high-risk sexual behaviors. The study found that those with mania are at an even higher risk for HIV and STIs, having significantly more sexual partners and being four times as likely to have an STI.
A new research paper proposes a six-step decision-making approach to facilitate shared decision-making between parents and physicians for infants born with genetic or anatomical anomalies in sexual development. The process aims to clarify reasons, identify gaps in understanding, and explore values underlying decisions. By working on th...
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Researchers found that depressive symptoms in men with erectile dysfunction increase cardiovascular problems independently from other known risk factors. The use of antidepressant medications did not alter this relationship.
Researchers found men with ED had a 54% greater likelihood of high-risk CACS compared to those without ED. The study suggests ED is an independent risk factor for future cardiovascular disease.
Boehringer Ingelheim announces new data on flibanserin in pre-menopausal women with Hypoactive Sexual Desire Disorder (HSDD), showing significant improvements in sexual desire and overall functioning. The study found that 48.3% of women receiving flibanserin reported feeling very much improved, compared to 30.3% on placebo.
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A recent study found that women taking hormonal contraceptives were at highest risk for Female Sexual Dysfunction (FSD), while those using non-hormonal contraceptives had the lowest risk. The researchers also discovered a significant association between smoking status and total sexual function scores.
A study published in Molecular and Cellular Proteomics identified 57 proteins that change during diabetes-induced erectile dysfunction, including those involved in cell death, fat metabolism, and sex hormone transport. These findings may lead to new diagnostic tools and drug targets for treating ED in diabetic patients.
Research finds that erectile dysfunction is a strong predictor of death from all causes and cardiovascular events in men with cardiovascular disease. Men with ED were more likely to suffer death, heart attacks, strokes, and heart failures compared to those without ED.
A new guideline recommends treatments to help people with Parkinson's disease manage sleep disorders, constipation and sexual problems. The guideline suggests medications like sildenafil citrate and isosmotic macrogol to improve erectile dysfunction and constipation.
A new study found that women with low sexual desire experience personal and emotional distress, including negative emotions like dissatisfaction and guilt. The study identified 5,098 women with low sexual desire, who reported significant correlations between their level of desire and associated distress.
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A study published in Sleep found that older men with restless leg syndrome (RLS) were more likely to experience erectile dysfunction. The association between RLS and erectile dysfunction was independent of other risk factors and was linked to hypofunctioning of dopamine in the central nervous system.
Flibanserin demonstrates significant improvements in sexual functioning, desire, and distress related to low sexual desire in pre-menopausal women with Hypoactive Sexual Desire Disorder (HSDD). The treatment increased satisfying sexual events and sexual desire, while decreasing distress associated with HSDD.
Flibanserin, originally developed as an antidepressant, has been shown to improve sexual desire and satisfaction in women with low libido. The results of pooled clinical trials found significant improvements in sexual encounters, desire, and distress associated with sexual dysfunction.
A recent study found that an abnormal Y chromosome structure called an isodicentric Y (idicY) can lead to spermatogenic failure in males. The researchers also discovered a correlation between the size of the idicY chromosome and the likelihood of sex reversal, potentially linking it to Turner syndrome.
A new study published in Obesity and Weight Management explores the link between obesity and erectile dysfunction, finding that excess weight increases the risk of ED due to atherosclerosis-related hypertension and hormonal changes. Research shows that weight loss and increased physical activity can improve symptoms.
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Researchers investigated a novel nanoparticle platform that releases therapeutic levels of nitric oxide, which aids in erection biology. Five out of seven rats treated with these nanoparticles experienced positive effects on erectile response, resulting in visible erections.
A randomized placebo-controlled study found no significant differences in electroretinography, visual function tests, or eye anatomy between men taking tadalafil or sildenafil and those taking a placebo. The study suggests that PDE5 inhibitors do not cause cumulative damage to the retina over six months.
A new study from Stanford University School of Medicine found that brain activity patterns differ in women with hypoactive sexual desire disorder compared to those without the condition. The research suggests that increased attention to one's own responses to erotic stimuli may play a role in sexual dysfunction.
A new Mayo Clinic study reveals that younger men with erectile dysfunction are twice as likely to develop heart disease as those without the condition. Men with erectile dysfunction also face an 80% higher risk of heart disease over a 10-year period.
A new study by UNC researchers found that postmenopausal women with hypoactive sexual desire disorder (HSDD) report poorer health status, worse quality of life, and physical symptoms such as back pain and memory problems compared to those without the disorder.
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Research suggests that sleep apnea can lead to erectile dysfunction due to chronic intermittent hypoxia. However, treatment with tadalafil can reverse the effects and improve sexual function in mice exposed to CIH for extended periods. Further studies are needed to explore alternative interventions.