Articles tagged with Pathology
A study found that errors in cancer diagnosis were relatively frequent and institution-dependent, with gynecologic errors resulting in harm in 45% of cases. The majority of errors were caused by sub-optimal specimen collection, while pathologist misinterpretation ranged from 5-50%.
Researchers found that the protein Klotho extends lifespan in mice by making them resistant to insulin, but also increases risk of diabetes. The study offers promising hope for developing anti-aging therapies.
The study found that gamblers and alcoholics have unique personality traits affecting their cravings, with gambling craving linked to positive emotions and alcohol craving tied to negative emotions. The research suggests that individuals with distinct emotional regulation patterns are more vulnerable to addiction.
Researchers created transgenic mice overproducing Ab40 and Ab42 to study their roles in AD pathology. The results showed that Ab42 mice accumulated extensive amyloid plaque and neural damage, while Ab40 mice showed little disease pathology. The study provides evidence for the critical role of Ab42 in initiating amyloid deposition.
A team of researchers from Case Western Reserve University propose an alternate view on the pathology of Alzheimer's disease (AD), suggesting that neurofibrillary tangles (NFTs) may be protective against oxidative stress. NFT-bearing neurons can survive for decades, and their presence may be a response to reduce oxidative damage.
Dr. Somerman received the award for her outstanding contributions to oral biology research, recognized as the Association's highest honor. The IADR Research in Oral Biology Distinguished Scientist Award is one of 15 bestowed annually by the IADR.
Researchers found that blocking CCL2 eliminates foreign body giant cells, protecting implants from damage. This discovery paves the way for a new class of therapeutic drugs to sustain implants and improve their functionality.
Researchers identified four severity classifications of chronic rhinosinusitis, including patients with polyps and high levels of eosinophils having the worst disease. The study suggests using a 'fingerprint of inflammation' obtained from a simple blood test to categorize patients and guide treatment.
Researchers found a mutation in the LRRK2 gene that plays a central role in developing Parkinson's disease and other neurodegenerative disorders. The discovery has major implications for understanding mechanisms of these diseases and potentially leading to curative treatments.
A recent study published in Molecular Psychiatry reveals that cell death promotes learning and growth in the brain. The research found that rats with lower levels of cell death performed better in spatial learning tasks, suggesting a positive correlation between cell death and cognitive function.
A study at Royal Hallamshire Hospital found that most death certificates were completed by junior medical staff, with only a third issued by senior members. Necropsy rates have declined since 1993, raising concerns about the impact of recent 'organ retention scandal'.
A study of retired physicians and their spouses found that both groups enjoyed very high life satisfaction following retirement. The happiest retirees were those who had chosen to retire at a young age and had progressed through the initial post-retirement adjustment phase. Factors associated with better life satisfaction for the physi...
A UCSF study found that macrophages from human lymphoma patients can cause mouse lymphoma when injected into mice. This contradicts the current understanding of macrophages' role in fighting disease. The researchers believe HIV-infected macrophages can become neoplastic and stimulate lymphoma growth.
A recent study suggests that users of the former Viadent formulation are eight to 11 times more likely to develop oral leukoplakia than those who have never used the product. Leukoplakia can sometimes lead to oral cancer, and patients with this condition should be alert for symptoms.
A study of 2,600 Americans found that between 1-2% have a compulsive gambling problem, with rates higher among minorities and lower-income individuals. Problem drinkers are 23 times more likely to also have a gambling issue.
Researchers at UCSD suggest that naturally occurring molecules called beta-synucleins (b-synucleins) may inhibit the excessive accumulation of Lewy bodies, which are characteristic of Parkinson's disease. In mice studies, b-synuclein was shown to block the formation of these abnormal deposits.
Researchers at Virginia Tech have discovered a way to stimulate the production of Vitamin C in lettuce and other plants using rat genes. This breakthrough could lead to longer shelf life and improved nutrition, particularly in developing countries where access to fresh produce is limited.
A recent court decision requiring all North Carolina speech-language pathologists to hold a master's degree may lead to a 13% workforce loss in the state's public school system. The shortage could exacerbate caseloads, particularly for students with autism and growing demands for early intervention services.
A study by Dr. David Bennett found that many people with mild cognitive impairment exhibit Alzheimer's disease pathology, indicating a larger public health problem than previously thought. The research suggests increased funding for clinical care and research is needed to combat the disease effectively.
A study of over 6,000 patients found that one in every 100 people misdiagnosed due to a single pathologist's report. This can lead to incorrect treatment, surgery, or chemotherapy, causing psychological trauma and financial burden.