Articles tagged with Pediatrics
A study led by Children's Hospital of Philadelphia found that lifelong immunoglobulin replacement therapy reduces premature deaths by 37% but is not cost-effective due to high costs. Reducing IRT prices could make it a more affordable option.
A large-scale trial found that penicillin can prevent progression of latent rheumatic heart disease in Ugandan children. The study enrolled 818 children and showed that early detection coupled with prophylactic treatment significantly reduced worsened heart conditions, offering hope for addressing this neglected disease.
A new prospective cohort study of 106 patients at Children’s National Hospital found that the second wave of kids with multi-system inflammatory syndrome in children (MIS-C) had more severe illness compared to the first wave. Despite this, both cohorts had similarities in cardiac outcomes and length of stay.
A study published in Microbiology Spectrum found that parent-collected nose swabs outperform nurse-collected swabs in detecting respiratory infections in children, with high inter-rater agreement rates for viral and bacterial infections. The study's findings suggest that parents can collect high-quality samples, and this method may be ...
The MC3 program provides a lifeline for primary care providers in Michigan, connecting them with psychiatrists and behavioral specialists for consultation and training. This has led to improved diagnosis and care for young people with mental health concerns, including those who express suicidal thoughts or have harmed themselves.
A UCLA study found that young adults experiencing discrimination are at a higher risk for short- and long-term behavioral and mental health problems. The study suggests that the effects of discrimination are connected to disparities in care and institutional discrimination, leading to inequities in diagnoses, treatment, and outcomes.
The American Pediatric Society (APS) has named Dr. Megan A. Moreno the recipient of the 2022 Norman J. Siegel Outstanding Science Award, recognizing her significant contributions to pediatric science and adolescent health. The award acknowledges her pioneering work on social media research and its impact on adolescent wellbeing.
A new mobile phone app called GrowthMonitor can accurately measure children's height and detect potential growth disorders, enabling early diagnosis and treatment. The app uses a traffic light system to inform parents of normal, amber, or red growth status, empowering them to take action.
A new study reveals that many young adults with asthma are not prepared to transition to adult asthma care. The survey found that half of all respondents did not receive sufficient transition preparation from their pediatric providers, highlighting the need for better education and support.
A pediatric practice in Rochester, NY, demonstrates success in vaccinating eligible patients and their caregivers during regular visits, showcasing a model for addressing vaccine hesitancy. The approach found positive outcomes, including increased comfort and trust among caregivers.
A new Dartmouth-led study found a direct association between the infant microbiome and early childhood behavioral health, with sex-specific differences. The study characterized the species of microbes present in each participant's gut and their functions, establishing that microbiome changes occur before behavioral changes.
A recent study published in PLOS ONE found that combining copper ions with a drug once used for treating alcoholism kills medulloblastoma cancer cells and prevents new ones from forming. The therapy also curtails the creation of cancer stem cells, which initiate tumor growth and recurrence.
Researchers at Children's Hospital of Philadelphia have developed a novel therapy that targets proteins essential for tumor growth and survival. Using a multi-omics approach, they identified peptides unique to neuroblastoma tumors, which are then targeted by peptide-centric chimeric antigen receptors (PC-CARs).
A seven-year study by CooperVision indicates that MiSight 1 day contact lenses slow myopia progression without a rebound effect, even after treatment cessation. The lenses demonstrate sustained slowing of myopia progression across different ages and with varying levels of myopia.
A large national sample of US adolescents showed an increase in average total daily screen time from 3.8 hours/day pre-pandemic to 7.7 hours/day early in the pandemic period.
A new study found that adolescents in the US doubled their non-school related screen time to 7.7 hours a day during the pandemic, leading to increased depression and anxiety. The study also revealed that children of color and those from lower-income families spent more time on screens than their white, wealthier peers.
Researchers at Johns Hopkins Medicine found that antibody levels against SARS-CoV-2 stay higher in people who were infected by the virus and then received protection from mRNA vaccine compared to those who only got vaccinated. A longer interval between virus exposure and first vaccine dose may enhance antibody response.
A new study found that COVID-19 can trigger severe psychiatric symptoms in adolescents, with anti-neural antibodies playing a potential role. Two patients with mild/asymptomatic COVID developed suicidal thoughts and paranoid fears, while another patient without prior psychiatric history recovered fully after treatment.
A nationwide pause of most elective operations led to significant financial losses for hospitals, with one study estimating a 42% loss of net revenue. Hospitals lost $1.53 billion from missed pediatric procedures, with a median time to recovery of one year.
A Rutgers study found that up to 8% of children in certain New Jersey communities have autism spectrum disorder (ASD), significantly higher than the national average. The study also identified disparities in ASD identification, particularly among Hispanic children.
Researchers found a higher burden of infection, more inflammation, and lower diversity of microorganisms in children with cystic fibrosis compared to disease controls. This divergence was noted as early as toddlerhood, suggesting potential for earlier treatment and prevention of severe lung disease.
Pediatricians and public health officials should present a united front against controversial state masking bans for schools, as these policies contradict evidence-based recommendations. The Delta variant overwhelmed pediatric emergency rooms and hospitals, highlighting the need for effective mitigation strategies.
A new study found that people with autism spectrum disorder are at a substantially increased risk of self-injury and suicide, with odds over three times higher than in non-autistic individuals. The study identified 31 studies showing statistically significant positive associations between ASD and self-harm.
A large community-based health care network found most preschool-age children with ADHD or symptoms were not offered evidence-based behavioral treatment. Pediatrician recommendations focus on alternative approaches to address the issue.
Researchers developed a new protein treatment that prevents glaucoma from forming in mice and reduces pressure in the eyes. The study provides new targets for therapies and aims to develop an injectable treatment for patients.
A group of researchers led by Indiana University School of Medicine's Benjamin Gaston will receive a research program project grant to fund the development of personalized therapeutic approaches for severe asthma. The grant will support three key projects focused on S-nitrosylation signaling, airway pH regulation, and androgen signaling.
A UC Davis MIND Institute study suggests telehealth evaluation can help families access care and diagnose autism earlier. The research found that telehealth approaches in the first year of life improved access to care for infants with elevated autism risk, reducing waitlists and parental stress.
New research from WVU suggests that live music can reduce pain and anxiety in pediatric critical-care patients. In a study, babies who heard live music had lower heart rates and slower breathing rates compared to those who listened to recorded music.
A multi-university study found that higher doses of intensive therapy improve upper arm and hand abilities in children with hemiparetic cerebral palsy, while a lower dosage produces fewer gains. The therapy can be life-changing for children, increasing their willingness to tackle new activities.
Researchers at UC San Diego will document brain development from birth through early childhood, focusing on environmental factors and mental disorders. The HBCD study aims to optimize brain imaging technologies and predict future behavioral problems.
New research from an international team of scientists found that poor timing of influenza vaccination campaigns in Brazil led to increased premature births, lower birth-weight babies, and the need for more cesarean sections. The study suggests that earlier flu vaccination campaigns could better protect pregnant women and their babies.
A new AI-powered algorithm, GEM, has been developed to quickly identify genetic causes of serious disease in newborns. The technology leverages machine learning and natural language processing to analyze vast amounts of genomic data and clinical records, achieving an accuracy rate of 92% compared to existing tools.
The study analyzed data from 680 patients aged 1-17 who were involved in ATV or dirt bike crashes. Helmeted riders had lower rates of neurosurgical consultation, intracranial injury, moderate or severe traumatic brain injury, and required fewer neurosurgical procedures compared to unhelmeted riders.
A CHOP-led study found that healthy full-term infants born during the COVID-19 pandemic had substantially shorter hospital stays, with a significant increase in early discharge rates. Despite shorter hospital stays, infant rehospitalizations within a week of discharge remained unchanged.
The University of Michigan's Injury Prevention Center has developed a free online course on pediatric injury prevention, which has gained significant popularity. The course offers tailored learning pathways and covers dozens of injury topics, making it accessible to learners worldwide.
Researchers at Keck School of Medicine will collect and analyze imaging data from over 1,300 children nationwide to identify biological markers predicting recovery or persistent symptoms after concussion. The study aims to develop a diagnostic protocol for clinicians caring for pediatric patients with concussion.
A survey of healthcare providers found that technology changes during the pandemic may contribute to burnout, with negative perceptions of telehealth visits increasing the odds of reporting burnout. The study highlights the need for adequate institutional resources to promote provider well-being and combat burnout.
Research shows that staff training programs and gun safety educational materials increase doctor/parent conversations about gun safety, leading to safer storage practices and reduced firearm injuries. Pediatricians who received training and support were more likely to counsel parents on gun safety, resulting in improved firearm screeni...
A new study from UCLA finds that a social companion robot, Robin, provides comfort to young patients during hospital visits. Children and their parents reported significant improvements in positive affect and reductions in negative affect after interacting with Robin compared to tablet-based interactions.
Research found a significant increase in non-accidental child injuries during COVID-19 stay-at-home orders, attributed to economic and emotional stress. The study analyzed data from nine pediatric trauma centers and found that the number of child abuse victims over age 5 tripled during the pandemic period.
A new study is examining the relationship between cytokines in saliva and COVID-19 infection to predict severity in children. Levels of two cytokines were found higher in those with severe COVID-19 compared to those without severe infection.
New research found that family violence-related injuries in youth ages 10-15 significantly increased during the pandemic stay-at-home order, with over half of patients reporting an event involving a family member. The study also revealed that alcohol, illegal drugs, and weapons were involved in more cases during the pandemic period.
A study found that pediatric clinical trials in the US were underrepresented by Black children, Hispanic/Latino children, American Indian/Alaska Native, Asian, and Native Pacific Islander children. Researchers are calling for improvements to enrollment processes to increase diversity and generalizability of trial results.
Research suggests that baby-wearing products pose a significant risk of injury to young children, with 61% of injuries occurring in children under 5 months old. The study found that 19.3% of these infants required hospitalization due to head injuries, highlighting the need for parent education on proper use and sizing of baby carriers.
A study found that bystander intervention can reduce the risk of drowning child deaths or severe disabilities by 80%. Children submerged under water for less than 5 minutes and rescued by a bystander were more likely to recover. Early rescue can lead to good outcomes in victims of drowning.
A study analyzing TikTok videos under the hashtag #preworkout found that dry scooping, where undiluted powder is put in the mouth followed by liquid, amassed over 8 million views. The study suggests physicians should be aware of pre-workout's dangers, especially among teens.
A Children's Hospital of Philadelphia-led study found that most US obstetric hospitals deliver fewer than 500 babies per year, with approximately 2.5 million infants born at low-volume hospitals between 2010 and 2018. Nearly a fifth of these low-volume hospitals are isolated from other obstetric hospitals, with over half located in rur...
A nationwide study found over 63,000 golf cart injuries in children and adolescents from 2010-2019, with a steady increase each year. The majority of injuries were superficial, but fractures and dislocations also occurred, often in the head and neck region.
A study of 1,236 participants in 310 households found that SARS-CoV-2 infection risks were similar between children and adults, regardless of household contact. The study provides insights into the clinical characteristics of SARS-CoV-2 infection among both age groups.
The COVID-19 pandemic led to a marked increase in accidental burns among children, with burn injuries growing significantly between 2019 and 2020. School-aged children accounted for the largest difference in burn injuries, and flame burns increased by 7% during this period.
A Michigan-based study found a dramatic drop in vaccinations across the lifespan during the early pandemic, but a recent rebound has been noted. The researchers emphasize the importance of continued vaccinations to prevent outbreaks of infectious diseases like measles.
Researchers developed a novel machine learning algorithm to identify previously unknown air pollutant mixtures linked to poor asthma outcomes in children. The study found that early exposure to individual and mixed pollutants can lead to longer-term problems with asthma, affecting about seven percent of US children.
Researchers at UC San Diego School of Medicine report that children with multisystem inflammatory syndrome in children (MIS-C) have normal T cell responses to the COVID-19 virus, contrary to previous hypotheses. This suggests that MIS-C may not be caused by an abnormal immune response to the virus.
A randomized trial found that a video game with biofeedback can help youth learn to regulate their anger, leading to reduced aggression and oppositional behavior. The game trains kids to stay calm during stressful situations, and its effectiveness was validated in parents' and clinicians' reports.
A new study found that 31% of children with food allergies experience victimization behaviors, including verbal teasing and criticism, compared to 17% when asked a simple yes/no question. Only 12% of parents reported being aware of the issue.
A groundbreaking study will follow 7,500 pregnant women and their infants across the US to understand healthy brain development. The five-year study aims to provide a comprehensive picture of normal variability in brain development and identify factors that pose the greatest risk.
Research finds that at-risk teen girls who have experienced sexual abuse are more likely to be cyberbullied and experience heightened offline sexual activities. Targeted intervention strategies using algorithm-based approaches could help these teens navigate the Internet safely.
The Charles Lazarus Children’s Abilities Center at Mount Sinai offers cutting-edge treatments for children with disabilities, including physical, occupational, and speech therapy. The center features state-of-the-art equipment and a multidisciplinary team of experts providing comprehensive care to children from birth to age 21.
A prospective study found that liver stiffness measurements obtained by shear-wave elastography decreased significantly after image-guided intervention for chronic Budd-Chiari syndrome in children. Disease recurrence was typically associated with an increase in liver stiffness measurements compared to prior assessments.
The researchers will develop techniques to analyze the joint growth of the brain and cranium using MRI scans, helping clinicians better assess and diagnose developmental disorders. The project has the potential to provide invaluable insights into healthy child development, enabling early detection and effective treatment.