Articles tagged with Pediatrics
Researchers at Keck School of Medicine will collect and analyze imaging data from over 1,300 children nationwide to identify biological markers predicting recovery or persistent symptoms after concussion. The study aims to develop a diagnostic protocol for clinicians caring for pediatric patients with concussion.
A survey of healthcare providers found that technology changes during the pandemic may contribute to burnout, with negative perceptions of telehealth visits increasing the odds of reporting burnout. The study highlights the need for adequate institutional resources to promote provider well-being and combat burnout.
Research shows that staff training programs and gun safety educational materials increase doctor/parent conversations about gun safety, leading to safer storage practices and reduced firearm injuries. Pediatricians who received training and support were more likely to counsel parents on gun safety, resulting in improved firearm screeni...
A new study from UCLA finds that a social companion robot, Robin, provides comfort to young patients during hospital visits. Children and their parents reported significant improvements in positive affect and reductions in negative affect after interacting with Robin compared to tablet-based interactions.
Research found a significant increase in non-accidental child injuries during COVID-19 stay-at-home orders, attributed to economic and emotional stress. The study analyzed data from nine pediatric trauma centers and found that the number of child abuse victims over age 5 tripled during the pandemic period.
A new study is examining the relationship between cytokines in saliva and COVID-19 infection to predict severity in children. Levels of two cytokines were found higher in those with severe COVID-19 compared to those without severe infection.
New research found that family violence-related injuries in youth ages 10-15 significantly increased during the pandemic stay-at-home order, with over half of patients reporting an event involving a family member. The study also revealed that alcohol, illegal drugs, and weapons were involved in more cases during the pandemic period.
A study found that pediatric clinical trials in the US were underrepresented by Black children, Hispanic/Latino children, American Indian/Alaska Native, Asian, and Native Pacific Islander children. Researchers are calling for improvements to enrollment processes to increase diversity and generalizability of trial results.
Research suggests that baby-wearing products pose a significant risk of injury to young children, with 61% of injuries occurring in children under 5 months old. The study found that 19.3% of these infants required hospitalization due to head injuries, highlighting the need for parent education on proper use and sizing of baby carriers.
A study found that bystander intervention can reduce the risk of drowning child deaths or severe disabilities by 80%. Children submerged under water for less than 5 minutes and rescued by a bystander were more likely to recover. Early rescue can lead to good outcomes in victims of drowning.
A study analyzing TikTok videos under the hashtag #preworkout found that dry scooping, where undiluted powder is put in the mouth followed by liquid, amassed over 8 million views. The study suggests physicians should be aware of pre-workout's dangers, especially among teens.
A Children's Hospital of Philadelphia-led study found that most US obstetric hospitals deliver fewer than 500 babies per year, with approximately 2.5 million infants born at low-volume hospitals between 2010 and 2018. Nearly a fifth of these low-volume hospitals are isolated from other obstetric hospitals, with over half located in rur...
A nationwide study found over 63,000 golf cart injuries in children and adolescents from 2010-2019, with a steady increase each year. The majority of injuries were superficial, but fractures and dislocations also occurred, often in the head and neck region.
A study of 1,236 participants in 310 households found that SARS-CoV-2 infection risks were similar between children and adults, regardless of household contact. The study provides insights into the clinical characteristics of SARS-CoV-2 infection among both age groups.
The COVID-19 pandemic led to a marked increase in accidental burns among children, with burn injuries growing significantly between 2019 and 2020. School-aged children accounted for the largest difference in burn injuries, and flame burns increased by 7% during this period.
A Michigan-based study found a dramatic drop in vaccinations across the lifespan during the early pandemic, but a recent rebound has been noted. The researchers emphasize the importance of continued vaccinations to prevent outbreaks of infectious diseases like measles.
Researchers developed a novel machine learning algorithm to identify previously unknown air pollutant mixtures linked to poor asthma outcomes in children. The study found that early exposure to individual and mixed pollutants can lead to longer-term problems with asthma, affecting about seven percent of US children.
Researchers at UC San Diego School of Medicine report that children with multisystem inflammatory syndrome in children (MIS-C) have normal T cell responses to the COVID-19 virus, contrary to previous hypotheses. This suggests that MIS-C may not be caused by an abnormal immune response to the virus.
A randomized trial found that a video game with biofeedback can help youth learn to regulate their anger, leading to reduced aggression and oppositional behavior. The game trains kids to stay calm during stressful situations, and its effectiveness was validated in parents' and clinicians' reports.
A new study found that 31% of children with food allergies experience victimization behaviors, including verbal teasing and criticism, compared to 17% when asked a simple yes/no question. Only 12% of parents reported being aware of the issue.
A groundbreaking study will follow 7,500 pregnant women and their infants across the US to understand healthy brain development. The five-year study aims to provide a comprehensive picture of normal variability in brain development and identify factors that pose the greatest risk.
Research finds that at-risk teen girls who have experienced sexual abuse are more likely to be cyberbullied and experience heightened offline sexual activities. Targeted intervention strategies using algorithm-based approaches could help these teens navigate the Internet safely.
The Charles Lazarus Children’s Abilities Center at Mount Sinai offers cutting-edge treatments for children with disabilities, including physical, occupational, and speech therapy. The center features state-of-the-art equipment and a multidisciplinary team of experts providing comprehensive care to children from birth to age 21.
A prospective study found that liver stiffness measurements obtained by shear-wave elastography decreased significantly after image-guided intervention for chronic Budd-Chiari syndrome in children. Disease recurrence was typically associated with an increase in liver stiffness measurements compared to prior assessments.
The researchers will develop techniques to analyze the joint growth of the brain and cranium using MRI scans, helping clinicians better assess and diagnose developmental disorders. The project has the potential to provide invaluable insights into healthy child development, enabling early detection and effective treatment.
Researchers at UIC will evaluate the effectiveness of integrated behavioral health care coordination on mental health outcomes for teens with intellectual and developmental disabilities. The study aims to identify better care coordination models to reduce barriers to access to behavioral health care for this vulnerable population.
Researchers found that parental knowledge and beliefs differ across socioeconomic status, but these beliefs can be changed. Interventions aimed at shifting parental beliefs had measurable effects on child outcomes, particularly in more intensive home visiting programs.
A recent study found that pediatric patients with Multisystem Inflammatory Syndrome (MIS-C) who received initial IVIG plus Infliximab had improved cardiac outcomes, reduced need for additional therapies, and faster resolution of inflammation. The updated care pathway recommends this intensified therapy for all MIS-C patients.
Pediatric transplant recipients have a more robust immune response to COVID-19 vaccines, achieving higher antibody levels after two doses compared to adult counterparts. This study suggests that the standard two-dose regimen may be safe and effective in pediatric transplant recipients.
Researchers at Mount Sinai have developed a novel therapy called MS67 that effectively fights acute myeloid leukemia with mixed lineage leukemia rearrangement. The therapy degrades the WDR5 protein, which drives the proliferation of this type of leukemia and other cancers such as pancreatic cancer.
A massive review of nearly 300 studies found strong associations between greenspaces near homes and schools and improved physical activity and mental health outcomes in kids. Exposure to nature, particularly for disadvantaged populations, offers greater health benefits by counteracting poverty's toxic effects.
Scientists identified a rare genetic condition affecting prenatal development, leading to lifelong disabilities in children. They discovered a potential method to prevent the condition by administering a drug during pregnancy, which boosted Wnt signaling and restored normal growth in mouse embryos.
A global study found that air pollution contributed to almost 6 million premature births and 3 million underweight babies worldwide. Indoor air pollution, mainly from cook stoves, accounted for two-thirds of the measured effects.
A new handheld screening device has been shown to accurately detect amblyopia (lazy eye) in children, with a sensitivity rate of 100% and specificity rate of 85%. Early detection is key to treating the condition, which can affect school performance and lifelong visual acuity.
Researchers have identified a specific gene, RARA, associated with acute myeloid leukemia (AML) in children that is sensitive to the treatment tamibarotene. Studies found that AML cells with high levels of RARA are more responsive to tamibarotene, suggesting its potential as a new treatment for pediatric AML.
Scientists at Ann & Robert H. Lurie Children's Hospital of Chicago discovered a surprising link between growth factor receptor PDGFRA and hypomyelination in mouse models. The study suggests that blocking this receptor could be a novel strategy to treat myelination disorders like multiple sclerosis.
A study at Hiroshima University analyzed 160 pediatric liver cancer cases, identifying molecular markers that help understand treatment outcomes. The research found that ASCL2 and IGF2 production play a crucial role in the disease's development, with 'cell of origin' being a premature hepatoblast.
A Cleveland Clinic-led research team found that statistically overweight children who followed a healthy eating pattern significantly improved weight and reduced various cardiovascular disease risks. The study also showed improvements in blood pressure, total cholesterol, and low-density lipoprotein levels.
Children who receive living donor liver tissue for transplants have nearly twice the survival rate and reduced risk of organ rejection compared to those receiving deceased donor livers. Living donation also shortens wait times for pediatric patients.
A parent-led therapy for early signs of autism has significantly reduced the likelihood of an autism diagnosis at age three. The iBASIS-VIPP program uses video-feedback to support social development and unique abilities, resulting in increased parental sensitivity and language development.
Children exposed to gun violence within a four-block radius are more likely to experience mental health distress, with symptoms appearing days after the incident. Researchers recommend reducing community violence through safe storage and background check laws, as well as providing preventive support for affected families.
A study found that oxcarbazepine, a commonly prescribed anti-seizure medication, is associated with a higher risk of fractures in children with epilepsy. The research team examined the effects of levetiracetam and oxcarbazepine on bone fragility in children between the ages of four and 13.
Researchers assessed diagnostic value of physical symptoms for urinary tract infections in children, finding only circumcision and diaper rash useful for ruling out UTI. They advise against restricting urine sampling to children with unexplained fever or specific features.
Researchers at Boston Medical Center have identified six stages of engagement in ADHD treatment, highlighting the importance of breaking down barriers for racial and ethnic minority families. The study provides a comprehensive framework that can help healthcare systems better match the needs of children with ADHD and their families.
A study published in SLEEP reveals an association between early lower respiratory tract infections and the development of obstructive sleep apnea in children. Children who had a history of severe RSV bronchiolitis during early infancy were found to have a higher risk of developing OSA.
Researchers developed an experimental device to improve blood sugar control in HI patients. The bihormonal bionic pancreas (BHBP) helps maintain stable glucose levels without human error in calculating doses.
A study found that gut microbiome profiles in children from the Democratic Republic of Congo reveal high glucosidase and low rhodanese microbes, which could increase susceptibility to konzo. The researchers plan to further investigate sibling pairs to confirm their findings.
Researchers at UC San Diego School of Medicine are studying the impact of antibiotics on breast milk and infant health. The team will investigate how antibiotics alter the composition of breast milk and impact the infant microbiome, metabolome and immune response.
Researchers found that patients with a rare genetic condition may develop chronic inflammatory bone diseases due to an impaired response to interferon gamma. The study suggests that this impairment leads to excessive osteoclast proliferation and increased bone resorption, causing multifocal osteomyelitis.
A randomized clinical trial of 125 young adults with concussions found that restricting screen time for 48 hours significantly reduced symptom duration. The study, published in JAMA Pediatrics, suggests that limiting screen time may be a useful strategy to accelerate concussion recovery.
A recent study found that breastfeeding mothers who received Pfizer-BioNTech or Moderna COVID-19 vaccines experienced temporary symptoms such as pain and swelling at the injection site, chills, muscle/body aches, fever, and vomiting. The study also reported no serious side effects in breastfed infants.
A new study suggests that T cell therapy alone or combined with cancer drug nivolumab is safe and persistent in attacking Hodgkin's lymphoma cells. The treatment showed promising results in patients with relapsed or refractory HL, offering a potential option for those who do not respond to checkpoint inhibitors.
A multinational team of researchers led by UNC principal investigators James Hagood and Richard Boucher aim to better understand how cells lining the nose, mouth, and airways interact to maintain respiratory health or play roles in diseases throughout childhood. The project involves collecting samples from six countries for cutting-edg...
Researchers found no significant DNA changes in stem cells after transplant, but an anti-virus drug called ganciclovir may contribute to cancer development. Further research is needed to investigate this further.
A study published in JAMA Pediatrics found that contact with police is associated with negative health outcomes for Black youth, including poor mental health, substance use, and risky behaviors. The researchers also found that Black youth experience feelings of alienation and hopelessness due to lack of support from social institutions.
A nationally representative survey found that 72% of people with food allergies were unaware of oral immunotherapy as a treatment option. The study highlights the need for more accessible and equitable outreach efforts to ensure all patients can benefit from recent advances in food allergy treatments.
A study published in the Journal of Clinical Investigation has identified potential biomarkers for COVID-19 condition in children, known as Multisystem Inflammatory Syndrome in Children (MIS-C). The researchers hope that these biomarkers can help predict the severity of the disease and inform treatment decisions.
A study of 68 patients found that most had good long-term outcomes with minimal complications, while others faced significant risks. The research provides insights into the potential consequences of COVID-19 multisystem inflammatory syndrome in children.
New study finds that rescue breathing cardiopulmonary resuscitation (CPR) is preferable to compression-only CPR for infants, children, and adolescents in case of cardiac arrest. Rescue breathing CPR was associated with higher odds of favorable neurological outcomes and overall survival compared to compression-only CPR.
A multicenter study will evaluate the outcomes of 1,500 children with tracheostomy to provide clinical practice guidelines for preventing, diagnosing, and managing bacterial infections. The study aims to reduce unnecessary antibiotic use and cost of care.