Articles tagged with Pediatrics
Dr. Lisa R. Young is recognized for her research and leadership in pediatric pulmonary medicine and rare lung diseases. Her work has led to a greater understanding of these diseases and will drive novel diagnostic and treatment strategies.
A single institution study found that half of children diagnosed with multisystem inflammatory disease in children (MIS-C) developed cardiac complications, including coronary artery abnormalities. The study highlights the need for further research into the syndrome's specific differences from Kawasaki disease.
A retrospective study of over 2,800 children with Type 1 diabetes reveals racial disparities in treatment modalities, clinical outcomes, and appointment attendance. Non-Hispanic Black children are more likely to have poor glycemic control and reduced long-term complications due to inadequate technology use.
A team of healthcare providers and advocates led by Pediatric Surgeon Lorraine Kelley-Quon established the first-ever guidelines for safe opioid prescribing in children. The guidelines acknowledge the risks of opioid misuse and addiction in teens and adolescents, while promoting education and safe storage/disposal practices.
A new study finds that e-cigarette use is associated with a higher risk of cigarette smoking among adolescents who had no prior intention of taking up conventional smoking. E-cigarette users are more than four times more likely to start smoking cigarettes one year later compared to non-users.
The American Pediatric Society recognizes Dr. Devaskar's outstanding leadership, research, and education efforts in pediatric medicine, particularly in neonatal care. Her work has made a significant impact on improving children's health and well-being, and she is an inspiration to many in the field.
A recent NIH study found that approximately 1 in 4 women experience high levels of depressive symptoms at some point in the three years post-childbirth. Women with underlying conditions like mood disorders and gestational diabetes are more likely to have persistent symptoms.
A Dartmouth study found that involving pediatric practices in promoting private well water testing can significantly influence parental compliance. The study, which tested two interventions, showed that providing both parents and clinic access to results and follow-up reminders increased testing completion rates.
A study of 339 asymptomatic and 478 symptomatic children found that those without symptoms had relatively low viral loads compared to their symptomatic counterparts. The timing of infection and diagnostic testing may impact viral load levels in asymptomatic children.
Dr. Penny M. Heaton is honored with the PIDS Distinguished Research Award for her outstanding contributions to vaccine clinical research and development. She leads efforts at the Bill & Melinda Gates Medical Research Institute, optimizing therapeutics, vaccines, and monoclonal antibody candidates.
A new study published in Pediatrics found that critically ill newborns who receive blood transfusions prior to surgery have a 50% increased rate of complications or death. The findings suggest that a 'wait and see' approach to giving infants blood during surgery may reduce surgical complications and the risk of death.
Children with chronic kidney disease experience prolonged hospital stays (30% longer) and increased hospital expenses ($8,755 vs. $5,016). They also have a higher risk of in-hospital mortality, with a 50% increase compared to other chronic conditions.
Patients with anorexia nervosa who received higher-calorie diets recovered faster and had shorter hospital stays compared to those on lower-calorie diets. The study found that patients in the higher-calorie group reached medical stability three days earlier and gained weight faster.
Three new trans-Atlantic research teams will tackle neuroblastomas, Ewing sarcoma and other difficult-to-treat cancers in children. They aim to develop precision radiotherapy, re-engineer T-cells for immunotherapies and target cancer-causing gene mutations.
A new study summarizes over 30 years of clinical experience in treating glutaric acidemia type 1 (GA1), a rare and devastating metabolic disorder. The clinic's therapies have reduced brain injury risk by 83%, improving treatment outcomes for individuals with GA1.
A computer model reveals that a specific region of the SARS-CoV-2 spike protein acts as a superantigen, triggering a massive immune response and leading to severe inflammation in some COVID-19 patients. The study also suggests that therapies targeting toxic shock syndrome may be effective for managing MIS-C and cytokine storm in adults.
A study found that non-driving-related license suspensions are given to over 90% of drivers in New Jersey, affecting low-income neighborhoods and communities of color. These suspensions disproportionately limit access to employment and healthcare, with failure to pay fines being the most common reason.
A Dartmouth-led study reveals that pediatric mental health boarding is a prevalent and understudied issue, affecting 40,000 to 66,000 youth admitted to hospitals each year. The research team found key risk factors for children, including age, suicidal thoughts, and seasonal hospital visits.
Researchers at Children's Hospital of Philadelphia developed a new study using a handheld device to measure pupil response to light, revealing clear differences between concussed and healthy adolescent athletes. The study found significant variations in pupil diameter, constriction, and dilation velocity among concussed athletes.
The National Comprehensive Cancer Network has published a new patient and caregiver resource focused on childhood cancer type, pediatric acute lymphoblastic leukemia. The guidelines provide easy-to-understand information on treatment options, including charts and images, to help patients and caregivers make informed decisions.
Researchers at Children's Hospital of Philadelphia found that cardiac involvement in multisystem inflammatory syndrome in children (MIS-C) is associated with myocardial injury, differing from Kawasaki disease. Long-term effects on cardiac function and sports participation require further study.
A randomised controlled study found that computerised training can support preterm children's academic success, particularly in math and attention skills. The study tested two learning apps, Xtramath and Cogmed, on 65 first graders born preterm.
A study found that children's immune responses are better equipped to fight COVID-19 than adults. Children possess higher levels of certain cytokines associated with the innate immune response, which helps protect them from developing severe disease.
The Texas Heart Institute will develop the first fully implantable circulatory support device for pediatric patients, aiming to stop advanced heart failure progression. Led by Dr. O.H. Frazier, the team will conduct preclinical studies and collaborate with international consultants.
A new study suggests that children and adolescents diagnosed with white-coat hypertension may progress to sustained hypertension if not monitored regularly. White-coat hypertension is a condition where blood pressure increases only in a doctor's office, but its impact on kids is unclear.
Researchers found that standard CDS systems are ineffective in reducing antibiotic prescriptions in EDs. The study suggests tailoring CDS systems to the ED environment and provider needs can help reduce unnecessary antibiotic use.
A study of 141 pediatric patients transferred to an adult rheumatology clinic found that continued insurance coverage and referral from a pediatric rheumatologist reduced delays in attending adult visits. Pediatric patients with connective tissue diseases or Black race were particularly vulnerable to unscheduled hospitalizations.
A 14-year-old boy's mysterious symptoms led to a rare diagnosis of multisystem inflammatory syndrome in children (MIS-C) caused by COVID-19. A new clinical pathway has been developed to quickly identify and treat cases, saving lives with timely information-sharing.
The special journal issue features Nemours pediatric cardiologists' expertise on echocardiography and other imaging techniques used in children with cardiovascular disease. The articles highlight best practices for screening, diagnosing, and managing congenital heart disease to improve patient outcomes.
Researchers at Children's Hospital of Philadelphia found convalescent plasma to be a safe treatment option for children with life-threatening COVID-19 cases. The study suggests that convalescent plasma may provide the greatest benefit for early-stage patients who have not yet generated endogenous antibodies.
Researchers aim to enroll patients aged 6-17 with moderate to severe PANS and evaluate the effectiveness of PANZYGA versus placebo in reducing symptoms. The study will also assess sustainability and functional impairment associated with PANS treatment.
A recent study published in Journal of Pediatrics found that COVID-19 patients, especially children under 16 years old, can have both the virus and antibodies in their system simultaneously. The study suggests that these children still pose a risk of transmitting the virus even if they have developed antibodies.
A unique strain of Shiga-toxin E. coli (STEC) has been identified through genomic analysis, revealing its genetic makeup and potential for severe disease. The study's findings may contribute to the development of vaccines against emerging STEC pathogens.
A recent study by McMaster University found that only 28% of new Canadian drugs have clear pediatric data, and many critical diseases lack approved treatments. This absence perpetuates 'off-label' drug use, which can lead to inadequate treatment or increased side effects.
A new study found that young adults who used legal performance-enhancing substances were more likely to report problematic alcohol use and drinking-related risk behaviors seven years later. The study highlights the need for government oversight and regulation of these substances, which can lead to health problems and worsen mental health.
A new study models the estimated time to clear surgeries postponed in Ontario due to COVID-19, predicting an 84-week backlog. The target is 717 surgeries per week, with a focus on prioritizing critical procedures.
Research suggests children with no COVID-19 symptoms may still shed virus for weeks, making them potential key vectors. The study's findings also highlight the importance of understanding viral shedding in asymptomatic patients and its impact on herd immunity.
A new study found that teen drivers and older adults are more likely to drive vehicles with fewer critical safety characteristics, putting them at higher risk of injury. Drivers from lower-income neighborhoods were also less likely to drive newer, safer cars.
A retrospective study from the University of Missouri-Columbia found that vertebral body tethering (VBT) is a promising alternative to posterior spinal fusion (PSF) for treating scoliosis in pediatric patients with growth remaining. VBT yields a high success rate, preserving mobility and correcting curves in 74% of patients.
A study published in Pediatrics found that artificial intelligence models can accurately identify well-appearing infants with fever who are at low risk for a serious bacterial infection. This could lead to a significant reduction in unnecessary invasive procedures, antibiotics, and hospitalizations.
A small pilot study found that treating gout with probenecid improves heart function and exercise performance in children with a specific type of heart defect. The study suggests that repurposing this medicine to treat heart problems in these patients may be effective without adverse effects.
A new study published in Pediatrics reports positive safety and early outcome data from 21 children with spinal muscular atrophy treated with gene therapy. The treatment, onasemnogene abeparvovec-xioi, is shown to be effective through age 2 years with proper screening and monitoring, but requires closer attention for potential liver is...
A new UCSF study found that the prevalence of SARS-CoV-2 among asymptomatic children mirrors the number of confirmed cases in the general population. Researchers developed an equation to estimate the number of infected students in a classroom based on local data, revealing risks ranging from 11% to 79%.
Pediatric outpatient visits for notifiable infectious diseases declined during the COVID-19 outbreak in Beijing. The study found a significant reduction in these visits due to strict public health measures, suggesting that other types of hospital visits were also affected.
A comprehensive pediatric study shows children can carry high levels of the virus and spread infection, contradicting previous assumptions. The study's findings have implications for reopening schools and daycare centers, highlighting the need for increased precautions to keep kids, teachers, and staff safe.
A recent survey of pediatricians found significant variability in recommendations for solid food introduction, leading experts to question the relevance of current guidelines. The long waiting period may delay peanut introduction and limit food diversity, which can decrease the development of allergic diseases in infants.
A study found that 11.4% of second-opinion radiology reports were ignored by clinicians, with sonography and pediatrics having the highest rates. The cost of these ignored reports could be substantial, estimated at €53,700 or approximately $63,427.
The American Academy of Pediatrics provides guidelines for safe K-12 school reentry, focusing on infection control measures, social distancing, and mental health support. Effective operational planning is crucial to minimize risks and ensure a smooth transition back to in-person learning.
A team of researchers linked genetic information with electronic medical records to identify the impact of genetic epilepsies on affected children's lives. They found associations between specific genes and clinical features, such as seizures and intellectual disability.
A new pediatric study finds significantly higher COVID-19 infection rates among minority and socioeconomically disadvantaged children in the US. The study mirrors disparities found in adult populations across the country.
Pediatric infectious disease experts provide recommendations on return to school for SOT children, considering factors like clinical risk, community transmission, and infection prevention measures. The majority of SOT recipients are expected to outweigh the risks and benefit from attending school.
Cerebral palsy affects children's gross motor skills and muscles, leading to stiffening and weakness. Rehabilitation interventions improve quality of life for individuals with CP, including botulinum toxin injections and robot-assisted gait training.
Dr. Emmanuel Katsanis is studying a new chemotherapy treatment for patients with blood-related cancers who undergo a specific type of bone marrow transplant procedure. The treatment, known as haploidentical BMT, has shown promising results in improving survival rates and reducing post-transplant complications.
Drs. Sallie Permar and Stephen Patrick have been awarded the fifth annual Gale and Ira Drukier Prize in Children's Health Research for their groundbreaking research on neonatal viral infections and opioid epidemic's impact on pregnant women and infants. Their work has informed national policy and offers hope to untold expectant mothers.
A recent study from Ann & Robert H. Lurie Children's Hospital of Chicago found that young children with mild to moderate COVID-19 have higher viral loads than older age groups, suggesting they can transmit the virus just as easily. This finding has significant public health implications for discussions on reopening schools and daycare.
Surgeons from Children's Hospital of Philadelphia propose categorizing surgeries into four classes based on urgency and risk. Class-1 emergency surgeries must happen right away, while Class-4 elective surgeries should occur once the pandemic has reached its low point.
Researchers developed a computational algorithm to analyze noncoding mutations across five major pediatric cancers. The study identified 1,137 structural variants affecting over 2,000 genes, highlighting their potential as cancer-causing mutations.
A new study shows that IUDs significantly reduce menstrual symptoms in adolescents with disabilities, including heavy bleeding and cramping. The research found that 65% of young women reported less bleeding and 95% kept their IUD after one year.
Researchers at Loyola University Medical Center identified common symptoms in pediatric acoustic neuroma patients, including hearing loss and vertigo. They also found that residual tumors in pediatric patients had a higher rate of regrowth than those in adults.
The National Pediatric Rehabilitation Resource Center aims to promote clinical trials research in pediatric rehabilitation. The center will fund up to $150,000 per year for pilot studies and offer educational resources to support the growth of the field.