Articles tagged with Pediatrics
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A review of pediatric COVID-19 imaging findings reveals unique characteristics, such as the halo sign and subpleural sparing. These features can help radiologists narrow the differential diagnosis, leading to optimal patient care.
A new device using controlled incremental filtration is being developed to safely and effectively separate white blood cells from blood in pediatric patients. This technology aims to increase access to cell-based therapies for children worldwide, providing a potentially transformative impact on their health and well-being.
Researchers compare whole-body diffusion-weighted MRI to FDG PET and find significant agreement in tracking tumor response to therapy, raising the possibility of using DW MRI as a replacement for CT scanning.
Children in rural communities face higher risk of debilitating lawnmower injuries, which can lead to amputations and lengthy hospital stays. The study found that over 80% of pediatric lawnmower injuries occur in Southern and Midwestern states due to warmer weather and ride-on mower prevalence.
Experts at UTHealth report a breakthrough in treating severe COVID-19 cases in children, illustrating that the disease can be successfully managed despite its severity.
Dexrazoxane has been shown to preserve cardiac function and reduce risk of severe cardiac events in pediatric patients undergoing chemotherapy for acute myeloid leukemia (AML). The study suggests dexrazoxane should be considered for cardioprotection in all pediatric patients undergoing standard chemotherapy for AML.
Hyperdiploid B-ALL, the most common subtype of pediatric leukemia, arises from a malfunctioning Condensin complex, Aurora B kinase, and mitotic checkpoint in cell division. Researchers have unveiled the molecular mechanisms underlying HyperD-ALL origin and progression.
A recent study found pediatric cancer trial enrollment decreased from 40-70% in the 1990s to 19.9% in the current study. This decline is partly attributed to improved treatments for common childhood cancers, shifting focus to rarer and higher-risk cancers.
A study by CHOP researchers found that continuous pulse oximetry monitoring is being used in infants with bronchiolitis who do not require supplemental oxygen. The use of this practice varies widely among hospitals, with some institutions using it as a safety net despite national recommendations against it.
Critical Path Institute (C-Path) has been awarded a U.S. Food and Drug Administration (FDA) contract to develop novel clinical outcome assessments for pediatric asthma. The project aims to create patient-focused drug development tools for children with asthma.
A study published in Pediatrics found racial disparities in pain management among children presenting to emergency departments with long-bone fractures. Minority children were more likely to receive analgesics, but less likely to receive opioids and optimal pain reduction.
Research from Drexel University suggests that screen time for babies and less parent-child playtime are associated with increased autism spectrum disorder-like symptoms. The study found a four percent greater risk of ASD-like symptoms with screen viewing at 12 months, and daily playtime reduced the risk by nine percent.
A new study estimates that for every child requiring intensive care for COVID-19, there are 2,381 children infected with the virus. The US CDC and state health departments should begin reporting confirmed cases by age group to understand the true extent of the outbreak.
The article provides valuable information for pediatric healthcare clinicians on managing children with COVID-19 and its complications. Key findings highlight the importance of vaccination, infection control measures, and monitoring for long-term effects.
Dr. Stephanie Roberts receives the SPR Bridging to Success Award for supporting transitioning pediatric physician-scientists. Her research focuses on understanding genetic variants affecting pubertal onset and reproductive disorders.
Children with COVID-19 can play a major role in disease transmission, even if they appear asymptomatic. Researchers are working to understand how the virus affects kids and develop strategies to minimize transmission from children to others.
Researchers found that most mass shootings (71.1%) occurred more than 10 miles from a pediatric trauma center, highlighting the need for preparedness and resources in all hospitals.
Dr. R. Rodney Howell is recognized for his innovative work in newborn screening, which has saved countless lives. He will receive the first Dr. Michael S. Watson Genetic and Genomic Medicine Innovation Award from the ACMG Foundation for Genetic and Genomic Medicine.
The ACMG Foundation for Genetic and Genomic Medicine has presented the Takeda/ACMG Foundation Next Generation Fellowship Awards to Dr. Aixa M. Gonzalez Garcia and Dr. Chen-Han Wilfred Wu. The awards provide funding for medical biochemical genetics subspecialty fellowship and clinical laboratory biochemical genetics training, respectively.
The ACMG Foundation/PerkinElmer Diagnostics Travel Award recognizes Dr. Kuntal Sen and Dr. Shagun Kaur's innovative primary care clinic initiative, which aims to provide dedicated care for children with genetic disorders.
A pediatrician used her clinical visits to educate families about the importance of completing the census. She aimed to minimize the negative effects of poverty and adversity on children by ensuring accurate data drives funding for critical resources like healthcare, schools, and nutrition programs.
A study published in JPGN found that proton pump inhibitors (PPIs) may increase the risk of fractures in pediatric patients. The analysis showed a significantly higher fracture rate in children exposed to PPIs, with a 20% higher probability of fracture compared to non-exposed children.
The Critical Path Institute (C-Path) has been awarded a grant to conduct stakeholder engagement on the FDA's proposed framework to enhance the pediatric medical device ecosystem. The framework aims to facilitate design, development, and commercialization of medical devices for children.
A review of COVID-19 infections in children reveals milder symptoms and lower risk of severe disease compared to adults. Children account for only two percent of hospitalizations and most recover within one to two weeks after symptom onset.
A study confirms racial disparities in treatment outcomes for pediatric brain cancer patients, with Black and Hispanic patients facing poorer prognoses after diagnosis and treatment, regardless of stage at diagnosis.
A new wireless, battery-charged monitoring system is being tested to provide clinical-grade care for premature babies and pregnant women in low-resource settings. The soft, flexible sensors offer advanced features such as crying and movement detection, allowing for early intervention and improved health outcomes.
A study published in Radiology analyzed chest CT images and X-rays of 14 teenagers with EVALI, revealing characteristic ground-glass opacity and subpleural sparing. The findings suggest that CT imaging is crucial for early diagnosis and timely management of the condition in pediatric patients
While the number of treatments for rare diseases affecting children has grown, nearly 7,000 conditions still lack treatment options. Federal incentives are being used more often to expand use of existing drugs rather than creating new ones.
Child access prevention laws, enacted in half of US states, reduced firearm fatalities in children under 15 by 13% compared to states with no regulations. States with the most restrictive laws had a 59% reduction, preventing an estimated 4,000 deaths.
Researchers evaluated association between state firearm laws and pediatric firearm fatalities from 1991 to 2016. The study found that certain laws may be effective in reducing child access-related deaths.
Researchers developed a novel computational algorithm to track pediatric sepsis epidemiology, providing more accurate data on outcomes and incidence over time. The algorithm showed an increasing incidence of sepsis among hospital encounters and mortality rates remained stable.
The Roberts Individualized Medical Genetics Center at Children's Hospital of Philadelphia has developed a centralized genetic testing model that has improved diagnosis and patient outcomes. The center's success highlights the importance of standardizing genetic testing across different clinical disciplines.
The Vaccine For Children (VFC) Program has increased vaccination rates and reduced social disparities among Medicaid-insured children. Pediatricians value the program for its ability to provide free vaccinations regardless of payment status, leading to improved overall vaccination rates.
A novel elective program for pediatric residents has increased time spent at home with newborns, leading to improved income and academic outcomes. The four-week rotation provides up to four weeks of paid leave, benefiting breastfeeding establishment and fetal health.
Caregivers and pediatricians identify transportation, childcare, and financial stress as key barriers to attending scheduled well-child visits. The study suggests that addressing these social determinants of health could improve attendance rates.
A multi-center study has identified a research-based ultrasound screening method that can predict which children with cystic fibrosis are at higher risk for advanced liver disease. The test shows promise in identifying patients who could benefit from targeted therapies to prevent the development of this life-threatening condition.
A new study finds that fewer than one in four gay, bisexual and questioning teenage boys have ever received an HIV test, despite high risk of transmission. The study identified factors that increase the likelihood of testing, including frank conversations with doctors about sexual health and testing.
A new study led by pediatric cardiologist Brett Anderson aims to uncover the reasons behind health inequities in poor children who undergo heart surgery. The research will analyze data from 11 hospitals across New York state to identify mechanisms driving disparities in outcomes.
The CHICA system, developed by Regenstrief Institute and IU School of Medicine, increased autism screening rates from zero to 100% at 24 months of age. The computerized decision support tool improved health inequities by automating the screening process, making it more accessible for underrepresented racial and ethnic minorities.
Treating childhood obesity is associated with improved psychological outcomes, including enhanced self-esteem and body image. Losing weight appears to be less crucial for improving self-esteem, but still important for bettering body image.
Gary M. Shaw, DrPH, receives the SPR's Douglas K. Richardson Award for his significant contributions to child health research. He has made substantial contributions to understanding genetic and environmental risk factors for human birth defects.
A comprehensive study of congenital heart disease found lower predicted long-term survival, higher remission rates, and lower prevalence in low-income countries compared to high-income nations. The study revealed a significant disparity in CHD mortality rates between countries, with most deaths occurring in infants under one year old.
Dr. Lindsay Burrage receives the SPR's Young Investigator Award for her research on urea cycle disorders, a paradigm for understanding rare diseases and developing new therapies.
Dr. Susan Furth is recognized for her exceptional mentorship and leadership in pediatric research, training dozens of post-doctoral fellows and junior faculty. She is also the principal investigator of the Children's Hospital of Philadelphia Pediatric Center of Excellence in Nephrology.
A new study found that less than 5% of children and teenagers who tested positive for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) had been previously diagnosed with the illness. The prevalence of pediatric ME/CFS was found to be higher among African American and Latinx youth.
Dr. Anna Penn, a leading researcher in preterm brain injury, receives the award for her outstanding work and commitment to training the next generation of translational researchers. She has conducted groundbreaking research on placental function and fetal brain development.
Dr. Dani Dumitriu, a pediatrician and neuroscientist, has been honored with the SPR's New Member Outstanding Science Award for her high-quality scientific research and contributions to pediatric academia. She is recognized for developing innovative avenues for retaining physician-scientists in basic research.
A team of researchers created the first cellular model of chronic granulomatous disease (CGD), a rare genetic condition that causes severe infections. The study's findings suggest that restoring NADPH oxidase function in defective cells could help develop new and more effective treatment strategies.
Commercially insured children in the US see pediatricians less often, with primary care visits decreasing by 14% and problem-based visits declining by 24%. The trend may be driven by higher out-of-pocket costs and changes in healthcare behaviors, including increased use of telemedicine and urgent care.
A study of over 4 million Medicaid claims records found that less than a third of adolescents and young adults who survived nonfatal opioid overdoses received timely follow-up addiction treatment. Only 1 in 54 youths received standard-of-care counseling and medications recommended by the American Academy of Pediatrics.
Sallie Permar, a pediatric researcher focused on neonatal viral infections, has been recognized with the SPR Award in honor of E. Mead Johnson. Her research has led to significant breakthroughs in understanding neonatal viral infections, including the development of vaccines for prevention of vertical virus transmission.
As demographics change, spina bifida patients' needs are evolving, highlighting the need for research on quality of life and social determinants. The article discusses emerging trends in spina bifida care and the importance of addressing health disparities among minority populations.
A new treatment protocol at Children's Hospital of Philadelphia reduced albuterol use in infants with bronchiolitis without compromising care. The protocol change prevented over 600 unnecessary treatments and did not impact patient admission rates or length of stay.
Researchers found that prehospital epinephrine administration was associated with improved return of circulation in pediatric patients with out-of-hospital cardiac arrest. However, there was no significant improvement in 1-month survival rates. The study suggests that prehospital epinephrine administration should be included in interna...
A new program has been shown to reduce abusive behaviors among middle school male athletes towards their female peers. The Coaching Boys Into Men program, which trains coaches to speak frankly with their male athletes about stopping violence against women and girls, was found to increase positive bystander behaviors by over 50% in part...
A new report from Cincinnati Children's Hospital Medical Center highlights the emotional toll of pediatric chronic conditions on families. The Roadmap Initiative, launched in 2017, provides a set of tools and resources for pediatricians to improve emotional health support, including strengths-based cognitive-behavioral therapy and mind...
Researchers at the University of Rochester found that parents' consistent bedtime enforcement is associated with longer sleep duration and better mental health outcomes for teenagers. The study suggests that even without pre-bedtime conflict, parents' role in setting bedtimes yields positive results.
A study examining childhood weight and obesity in adolescence found that excess weight at age 3 was associated with a higher risk of being overweight or obese at age 15. Pre-pregnancy overweight/obesity in mothers was also a significant predictor of this outcome.
Colombian infants exposed to Zika virus in the womb showed neurodevelopmental delays despite having normal brain imaging and head circumference at birth. The study found a link between subtle brain injuries and impaired neuromotor development in Zika-exposed children, emphasizing the need for long-term follow-up.
A new study published in Annals of Thoracic Surgery found that many 'high-risk' donor hearts can be transplanted with similar survival rates as 'low-risk' donor hearts. The researchers, led by Dr. David Morales, used a risk-based matching system to match donors with recipients and found that the results were promising.