Articles tagged with Surgery
Cyclosporine and its nonimmunosuppressive analog NIM-811 reduce liver damage and inflammation after ischemia-reperfusion injury. The study suggests these compounds may mitigate IRI during liver transplantation and resection.
Researchers developed a device with AI algorithms to analyze suckling strength and pattern in newborns. The system showed improved accuracy over subjective clinician assessments, identifying abnormal patterns that may indicate the need for surgical intervention or improved feeding practices.
Researchers have developed a novel rigid endoscope system for visible-to-OTN hyperspectral imaging, enabling non-destructive imaging and visualization of lesions in normal tissues. The system demonstrated high accuracy in classifying molecular vibration information of various targets with an OTN wavelength range.
A recent study found that preoperative GLP-1 receptor agonist use is not associated with an increased risk of postoperative respiratory complications. The results suggest liberalizing withholding guidelines for these medications may be beneficial.
A new study from Israel found that nearly 1 in 5 adults with congenital heart disease developed an abnormal heart rhythm during a five-year study. Those who developed arrhythmias had twice the risk of early death and increased hospitalization rates compared to those without irregular heart rhythms.
A phase 3 trial shows that pembrolizumab significantly prolongs overall survival in high-risk kidney cancer patients. The treatment delays recurrences and helps patients live longer, with a 38% reduction in risk of death compared to placebo.
A study by the University of Gothenburg found that women with triple-negative breast cancer and high immune cell levels have a lower relapse risk after surgery. This suggests that these patients may not need chemotherapy, despite having faster-growing tumors and higher relapse rates than other breast cancers.
A new online curriculum and simulation training program, developed by Penn State researchers, significantly reduced complications in central line placement. The program, launched in 2022, has been shown to decrease error rates for mechanical issues, infections, and blood clots.
Researchers developed a new treatment method using plasma irradiation to speed up bone healing. The study found that displaced fractures exhibited stronger unions than nonirradiated ones, with strength increased by 3.5 times.
Endoscopic sleeve gastroplasty is a cost-saving option compared to semaglutide for treating class II obesity. A study found that achieving price parity with semaglutide requires a significant discount of at least 3-fold.
A pilot study by UCLA Health investigators suggests that treating patients with immunotherapy and chemotherapy before surgery may improve long-term outcomes for those with borderline resectable pancreatic cancer. The study found a higher rate of successful tumor removal and increased overall survival when compared to historical controls.
A new study from Washington University School of Medicine found that nerve-stimulation treatment for obstructive sleep apnea is less effective for people with higher BMIs. The study analyzed data from 76 patients with BMIs of less than 35 and showed that the likelihood of successful treatment drops significantly as weight increases.
A digital health platform with one-on-one telehealth coaches significantly improves patient adherence to pre-surgical preparation and post-surgical recovery guidance. Patients who used the platform had shorter hospital stays and lower risk of readmission compared to those who didn't use it.
Researchers found a link between Fontan circulation and accelerated epigenetic aging, which can cause complications like osteoporosis and renal impairment. The study suggests this acceleration starts in childhood and continues into adulthood, with potential new treatment opportunities to delay progression.
A survey study found that one-third of surgical residents reported lacking meaningful mentorship, with non-white or Hispanic trainees disproportionately affected. The study emphasizes the need for efforts to facilitate mentorship and improve education and wellness outcomes for all residents.
A long-term study found that coronary heart patients who live in greener areas have a significantly lower risk of mortality after undergoing bypass surgery. The study, which followed over 3,000 patients for 14 years, found that living in a green environment was associated with better chances of survival.
Researchers have developed an implantable battery that runs on the body's own oxygen, providing stable power and compatibility with biological systems. The device shows promise for powering medical devices, monitoring wound healing, and even starving cancer cells.
Researchers assessed the feasibility of dual PD-L1/CTLA-4 checkpoint inhibition in Stage II or III hormone receptor-positive, HER2-negative breast cancer. Eight patients received upfront durvalumab and tremelimumab prior to neoadjuvant chemotherapy, showing mixed responses and limited benefit.
A large retrospective cohort study found no increased risk of cauda equina syndrome in adults with low back pain who received chiropractic spinal manipulation. The study analyzed over 130,000 patients and suggested that underlying disc degeneration may be a risk factor for CES regardless of treatment approach.
A randomized clinical trial has shown that delaying surgical repair of inguinal hernias in preterm infants until after discharge from the NICU reduces serious adverse events. The study found a high likelihood of hernia resolution with late repair, allowing for quicker hospital discharge.
The COVID-19 pandemic caused a significant decrease in colorectal cancer surgeries, with patients undergoing procedures having more advanced stages of cancer compared to those treated in 2019. The study found that approximately 10,000 fewer patients did not have surgery for colorectal cancer in 2020.
New studies find over half of new doctors experience some form of sexual harassment in their first year, with women and men experiencing varying rates of recognition and types of harassment. The #MeToo movement has led to increased recognition of what constitutes harassment, but more work is needed for medical schools and hospitals.
A multi-institutional team is creating innovative technologies to reduce complications associated with left ventricular assist devices (LVADs), including infection, thrombosis, stroke, and bleeding. The new LVAD will deliver a physiological response to changes in the recipient's activity levels using a 'smart' Maglev drive technology.
A new AI tool can predict which breast cancer patients are at risk of chronic arm swelling after surgery and radiotherapy. The tool, developed by international researchers, uses machine learning algorithms to analyze patient data and provides easily understandable explanations for doctors and patients.
A new study from Johns Hopkins Medicine found that circulating tumor DNA levels can accurately assess how gastroesophageal cancers respond to treatment and predict future prognosis. The study tracked minimal residual disease by analyzing ctDNA, showing a correlation between ctDNA clearance and cancer-free survival.
A Northwestern University team developed a wireless, implantable temperature sensor to monitor inflammatory flareups in patients with Crohn's disease. This allows clinicians to act earlier to prevent permanent damage caused by inflammatory episodes.
A study published in Lancet Gastroenterology & Hepatology found that not placing a drain during distal pancreatectomy surgery improves patient outcomes. The study, involving 282 patients across ten Dutch and two Italian hospitals, demonstrated a significant reduction in postoperative pancreatic leaks and overall morbidity.
Research highlights new findings on social vulnerability and survivorship after colorectal cancer resection, as well as disparities in kidney recovery among Black donors. Additionally, studies reveal cost savings from implementing quality interventions and explore eligibility for transplants in obese patients with end-stage renal disease.
The study found a significant decrease in newly diagnosed breast cancer cases, with the largest declines seen among women aged 50-69 and Hispanic women. The results have implications for how physicians and policymakers address issues related to diagnostic delays during the pandemic.
Researchers found that patients recovering from robotic lung surgery do not fully recover even after 90 days, despite common expectations. The study suggests a more thoughtful approach to pre-surgery communication with patients is needed to better understand their recovery experiences.
Researchers at Children's Hospital Los Angeles found significant variation in opioid treatment for critically ill infants across different institutions and geographic regions. The study reports wide variability in opioid prescribing practices, which can impact hospitalization length of stay, healthcare costs, and long-term outcomes.
A collaborative study found that patients with end-stage renal disease who undergo weight loss surgery can experience significant improvements in BMI, hypertension, and diabetes management. This enhancement of overall health and transplant viability offers hope for previously ineligible patients.
A multicenter randomized trial showed a paclitaxel-coated balloon to be superior to an uncoated balloon in preventing target lesion failure in patients with coronary in-stent restenosis. The study included 600 patients and demonstrated the effectiveness of paclitaxel-coated balloons as a treatment option.
Patients living in areas with severe primary care shortages have a higher risk of emergency surgery, complications after surgery, and readmission. The study highlights the need for efforts to increase training and geographic distribution of primary care providers.
A new study quantifies a dramatic rise in school shootings and related fatalities over the past 53 years. The study found that the likelihood of children being a school shooting victim quadrupled between 1970 and 2022, highlighting the need for preventative measures.
Seven high-impact studies will be showcased, exploring novel therapies and improving treatment outcomes for patients with head and neck squamous cell carcinoma. These findings highlight advancements in immunotherapy, risk-directed adjuvant therapy, and FDG-PET-based selective de-escalation of radiotherapy.
Patients with behavioral health disorders (BHDs) are less likely to undergo surgical resection and face a higher probability of complications, extended hospital stays, and readmission. BHDs increase healthcare costs by 7.76% and worsen prognosis in cancer patients.
A new review at ECCMID 2024 will examine improving preventive measures to stop surgical infections. It highlights the need for evidence-based recommendations, citing examples such as pre-surgery showering and instrument handling, while acknowledging inconsistent practices.
Researchers found that synthetic PIC gel can stimulate cell growth and increase collagen production, potentially improving wound healing after pelvic organ prolapse surgery. The study also showed a mild immune response to the gel when tested on laboratory animals.
A new Yale study found that older Americans have a high risk of hospital readmission within 180 days of undergoing major surgery. The risk is particularly acute for individuals with geriatric-specific conditions such as frailty and dementia, with rates of readmission ranging from 27.6% to 39%.
The study found that bariatric surgery improved blood sugar control and reduced diabetes medication use more effectively than medical and lifestyle modifications. Bariatric surgery also led to superior cholesterol and triglyceride levels, which can contribute to fewer heart attacks and strokes.
A study compared traditional logistic regression models and machine learning algorithms to predict the best surgical technique for patients with submucosal tumors. The traditional regression approach was found to outperform ML algorithms, with morphology ranking as the highest contributor to prediction accuracy.
After 7 to 12 years of follow-up, bariatric surgery outperformed medical/lifestyle intervention in achieving superior glycemic control with reduced medication use and higher rates of diabetes remission. Individuals who underwent bariatric surgery had better long-term management of their type 2 diabetes.
Researchers successfully performed robot-assisted remote radical distal gastrectomy for stage T2N0M0 gastric cancer using 5G communication technology. The procedure demonstrated minimal intraoperative delays and no packet loss, highlighting the potential of 5G to advance remote surgical procedures.
A new AI system is being developed to provide real-time feedback and instruction for surgical trainees, addressing the need for constant supervision in laparoscopic surgery. The system uses computer vision model to detect the student's actions and provides immediate assessment and training direction.
A UK study published in Anaesthesia found that black children are at a significantly higher risk of postoperative complications following emergency appendicitis surgery, with a four-fold greater risk compared to white children. The study also identified other risk factors for complications, including pre-existing medical conditions and...
Researchers developed a wireless device powered by light that can be implanted to regulate cardiovascular or neural activity in the body. The ultralight membrane is thinner than a human hair and contains no moving parts, offering a minimally invasive surgery alternative.
Researchers found that pulse oximeters underestimate blood pumping and overestimate resistance, affecting treatment decisions. Direct blood oxygen measurement is crucial for accurate guidance, especially for Black patients already at higher risk.
Researchers developed a portable, droplet-based millifluidic device to monitor patients in the critical first days after surgery. The device measures drainage fluid's alpha-amylase activity in real time, reducing test duration from six hours to two minutes.
A new study in tens of thousands of people with obesity shows the impact of different weight management treatments on achieving a 5% weight loss. Effective treatment options include nutrition counseling, medically supervised meal replacements, anti-obesity medications, and bariatric surgery.
Researchers found that 86 patients experienced severe residual paresthesia after spinal surgery, leading to lower satisfaction rates. Patients with pre-surgical pain were more likely to have persistent paresthesia, highlighting the need for treatment strategies for this condition.
A new screening tool has been developed to catch endometrial cancer cases earlier, saving lives. The partnership between Pennington Biomedical's Metamor Institute and the LSU School of Medicine has already screened over 2,000 women and found abnormal bleeding in many cases.
A study of over 250 patients with Cushing's disease and nonfunctioning pituitary adenomas found that those who achieved remission were more likely to develop new-onset autoimmune disease within three years. Higher prevalence of adrenal insufficiency may have contributed to this development.
Weight loss treatments such as nutrition counseling and bariatric surgery increased the patient-level probability of achieving significant weight loss. Current treatment utilization rates are insufficient to impact the population level, highlighting a need for improved access.
A new study has found that routinely changing surgical gloves and instruments is cost-effective and safer, reducing surgical site infections (SSIs) by 13% in seven low- and middle-income countries. The economic evaluation, funded by the UK's National Institute for Health and Care Research, compared the costs and SSIs associated with ro...
A new study suggests that including socioeconomic status in the calculation of Medicare readmission penalties would reduce penalty amounts for 38% of safety-net hospitals compared to 17% of non-safety net hospitals. This adjustment could help alleviate financial pressure on these hospitals, which often care for sicker patients with lim...
Researchers found that bariatric surgery led to improved cognition and overall well-being two years after the procedure. The study revealed changes in blood vessel efficiency and cortical thickness of the temporal cortex, offering new treatment options for patients with obesity and dementia.
A randomized clinical trial of 1,680 patients with acute ischemic stroke due to large-vessel occlusion found no significant improvement in disability with adjunctive methylprednisolone. The study suggests that methylprednisolone may not be effective as an adjunct therapy after endovascular thrombectomy for this patient population.
A machine learning study of 22,000 surgical cases found that models can inform individual prognosis and aid in decision-making to reduce ineffective spine care. The findings suggest that these models may improve outcomes for patients undergoing lumbar disc herniation surgery.
A team of researchers analyzed 61 symptomatic and 35 asymptomatic knees with discoid lateral meniscus surgery. They found that larger meniscus sizes were associated with increased knee pain and symptoms. The study's results have important implications for surgical treatment and preoperative imaging.