Articles tagged with Surgery
A new study published in Transfusion journal reveals sex-based disparities in the transfusion of whole blood to traumatically injured patients. Women, particularly younger females and those of childbearing potential, are less likely to receive whole blood transfusions compared to men. This disparity is despite whole blood being associa...
A new class of antibiotic has been shown to be effective in treating MRSA infections, with a daily dose of epidermicin NI01 demonstrating equal efficacy to the current standard of care. The findings justify further pre-clinical development and could lead to new gel-type therapies for skin infections.
A survey conducted among ESTS members revealed that sympathetic surgery is commonly used for hyperhidrosis and facial flushing, with a preference for nerve cutting over clipping. However, there was significant heterogeneity in practice, highlighting the need for standardization and further research.
A recent study found that ischemic stroke mortality rates have increased in the US over the past two decades, particularly among racial minorities and rural residents. The majority of these deaths now occur at home, rather than in hospitals or medical facilities.
A study found that New York's opioid restriction law led to decreased opioid quantities after total joint replacement surgeries. The findings suggest refining laws may further reduce opioid prescribing nationwide.
A new case report presents a highly unusual combination of two benign ovarian tumors: serous cystadenofibroma and collision lesions. Accurate preoperative diagnosis is critical for effective treatment planning, and this case emphasizes the need for personalized evaluation of each ovarian mass.
A clinical trial has shown that administering clotting factor concentrate (4F-PCC) significantly reduces the risk of severe bleeding after major open-heart surgery. This innovative treatment approach offers a more effective alternative to frozen plasma for managing surgical bleeding.
A randomized clinical trial found prothrombin complex concentrate to have superior hemostatic efficacy compared to frozen plasma in patients requiring coagulation factor replacement during cardiac surgery. The study also showed safety advantages for the use of prothrombin complex concentrate.
Patients with hormone receptor-positive and HER2-negative breast cancers face a higher risk of death from the cancer if they wait more than 42 days after diagnosis to have surgery. Delayed surgery increases the patient's risk exponentially, with risks of death increasing by 21%, 79%, and 183% at 60, 90, and 120 days, respectively.
A new surgical technique called NeuroSAFE has been shown to preserve erectile function in men with prostate cancer, with 39% of patients experiencing no or mild dysfunction after treatment. This is compared to 23% of those who received standard surgery.
A TB vaccination has been shown to boost the immune system of bladder cancer patients, reducing cancer recurrence rates by up to 75% in a small pilot study. The vaccine was well-tolerated with no side effects and showed promising results in improving patient outcomes.
A wearable t-shirt with sensors monitors vital signs and detects complications, allowing patients to be discharged 24-36 hours earlier than control group. The device also improved patient satisfaction and quality of life.
Researchers found that detectable mutant KRAS circulating tumor DNA (ctDNA) indicates a higher risk of cancer spread and worse survival rates for patients with pancreatic ductal adenocarcinoma. The study suggests that ctDNA assays should be performed prior to treatment to have the highest yield.
A multicentre study led from Finland has shown that lymph node transfer is a viable treatment for swelling in the affected limb after breast cancer surgery. The procedure involves transferring patient's lymph nodes to the armpit to replace removed lymph nodes, improving excess arm volume and reducing skin interstitial fluid.
Researchers found that exposure to persistent organic pollutants (POPs) stored in body fat leads to disruptions in lipid metabolism and altered prostaglandin pathways, contributing to long-term higher blood pressure in adolescents. POPs diminish the beneficial effect of bariatric surgery on improved blood pressure.
A new analysis by UCLA Health finds that psychological prehabilitation can significantly enhance recovery after surgery, reducing hospital stays and pain. The study also found that psychotherapy-based interventions can lower anxiety and depression levels after surgery.
A randomized trial found that adenotonsillectomy surgery reduced healthcare utilization in children with mild sleep-disordered breathing by 32% fewer doctor visits and 48% fewer prescriptions. This effective early intervention supports reducing behavioral, neurocognitive, cardiovascular, and cardiometabolic issues.
Researchers found that the current standard monitoring time of one-and-a-half to two months following surgery is too short to accurately identify recurrence and inform treatment decisions. Monitoring PSA levels for at least three months can avoid overtreatment and mislabel patients as having recurred.
Researchers at MD Anderson have made significant breakthroughs in understanding pancreatic cancer's evolutionary process and developing new treatment strategies. They also discovered that surgical resection can enhance antitumor response in patients receiving immune checkpoint therapy for advanced kidney cancer.
Recent research suggests that some invasive cancers diagnosed in early-stage breast cancer may not need immediate surgery, highlighting the importance of more precise screening methods for DCIS. The COMET trial found that at least half of invasive breast cancers take years to progress or may never progress at all.
The article explores the role of AI in engineering, highlighting benefits such as improved transportation and manufacturing, but also raises concerns about safety, privacy, bias, and governance. The authors discuss weaknesses in data-driven models and call for research into regulatory frameworks to address these issues.
A new study introduces an online tool to guide surgical decisions for gallbladder cancer, identifying key risk factors that can help predict futile surgery. The tool may improve overall survival rates and reduce unnecessary risks for patients with advanced-stage disease.
A study of 350 patients found that taking semaglutide before bariatric surgery did not increase total weight loss and had similar health outcomes to surgery alone. Researchers suggest a surgery-first strategy may lead to better obesity treatment outcomes.
Patients undergoing surgery immediately before a weekend experienced significantly higher risks of postoperative complications, hospital readmissions, and death compared to those treated after the weekend. The study emphasizes the need for improved care quality regardless of the day of the week.
A cohort study found no significant association between preoperative GLP-1 RA use and short-term postoperative aspiration pneumonia. The study suggests reassessing preoperative withholding guidelines for GLP-1 RAs. Researchers hope this finding can help alleviate growing concerns about adverse effects of these medications after surgery.
The concomitant Cox-Maze procedure with aortic valve replacement in patients with atrial fibrillation showed lower rates of atrial fibrillation and higher anticoagulation discontinuation rates. Long-term outcomes were favorable, with no significant increase in early mortality or morbidity.
A recent study from the University of Gothenburg found that dental implants continue to function well after nearly forty years. The implants, developed by Professor Per-Ingvar Brånemark, have been shown to remain stable and integrate with bone over an extended period.
Researchers at Osaka Metropolitan University have successfully generated feline embryonic stem cells, a major breakthrough for veterinary regenerative medicine. The high-quality stem cells can differentiate into various cell types and be transplanted to restore internal damage.
Surgical adhesions form after surgery, causing severe complications like bowel obstructions, chronic pain, and infertility. A new report explores solutions to this widespread problem, including the development of standardized tools and innovative treatments.
A new stem cell transplant treatment has shown promising results in clearing clinical safety hurdles for the treatment of wet age-related macular degeneration. The treatment involves removing abnormal blood vessels and transplanting stem cell-derived retinal cells to replace damaged or lost retinal cells.
A novel LASSO-derived model was developed to predict coagulation disorders after coronary artery bypass grafting (CABG) in elderly individuals. The model demonstrated good prediction performance, identifying preoperative and intraoperative variables associated with coagulation disorders.
Preoperative anemia is a recognized risk factor for adverse outcomes in CABG, but it does not affect the long-term survival advantage associated with CABG. This study provides evidence that surgical intervention can still be beneficial for ICM patients despite preoperative anemia.
A new study found that interventions before, during, and after abdominal surgery did not reduce the severity of lung complications in patients compared to usual care. Lung function can make recovery more difficult and increase the risk of serious complications.
Increased visceral adipose tissue density and decreased skeletal muscle area are predictors of post-esophagectomy pulmonary complications. Decreased skeletal muscle density is associated with poorer overall survival. Routine morphomic analysis can help identify patients at risk and tailor perioperative care.
A cohort study found that patients with obesity undergoing joint replacement who experienced significant weight loss after initiating anti-obesity medications had a lower risk of 5-year and 10-year revision. This suggests that safe and sustainable weight loss may improve implant survivorship in obese patients.
A study at Michigan Medicine found that using less polluting inhaled anesthetic agents reduced CO2 equivalents by over 14 kg per case. This resulted in a 50% decrease in harmful emissions without impacting patient safety or outcomes.
A rare case of adenomyosis in an 81-year-old postmenopausal woman closely resembles invasive endometrial cancer, emphasizing the challenges of diagnosing this condition. Further studies are needed to refine diagnostic protocols and determine risk factors for postmenopausal patients.
A long-term study found that Roux-en-Y gastric bypass outperforms sleeve gastrectomy in treating obesity, with patients losing more excess body mass index. The Swiss Multicenter Bypass or Sleeve Study demonstrated the superiority of Roux-en-Y gastric bypass over sleeve gastrectomy for patient weight loss.
Researchers at Worcester Polytechnic Institute are developing a lightweight, flexible robotic arm that enables wheelchair users to safely grasp and carry objects out of reach. The project builds on origami-inspired designs and novel fabrication methods for modules made of lightweight plastics, 3D printed components, and sensors.
A University of Cincinnati researcher has been awarded a $2.1 million grant to investigate postoperative pain at the molecular and cellular levels. The goal is to develop new, safer non-addictive treatments for chronic pain conditions, including lower back pain and pain associated with diabetes or chemotherapy treatments.
The percentage of rural patients traveling over 60 minutes to obtain surgical care significantly increased between 2010 and 2020. This disparity persists due to factors like rural hospital closures and workforce shortages, contributing to growing healthcare access issues for these patients.
A new study published in the European Journal of Cardio-Thoracic Surgery found that mechanical heart valve replacements have better long-term survival rates compared to biological valves. Patients who received mechanical valves had improved survival up to 13 years after surgery, with smaller valves showing greater benefits.
Researchers at Osaka Metropolitan University assessed target genes in canine hepatocellular carcinoma (HCC) to develop molecular targeted therapies. The study identified potential gene targets, including PDGFB, which may improve treatment options for unresectable HCC.
A new study at U-M Health shows that hospitals can focus the use of preoperative tests on high-risk patients, while safely reducing unnecessary testing in others. The result is less wasted money and resources, as well as less time wasted for patients and clinical staff.
Dr. Hartzell Schaff is recognized for his transformative contributions to cardiovascular medicine, with over 1,200 peer-reviewed papers and nine textbooks to his name. The award celebrates his impact on surgical techniques and patient care worldwide.
Researchers successfully reversed existing inguinal hernias in male mice using an anti-estrogen drug, restoring their anatomy without surgery. Human tissue samples also showed identical molecular markers as in the mouse model, suggesting a promising treatment target for inguinal hernia repair.
Sucosky's research aims to build a device replicating the bicuspid aortic valve to investigate how unusual stress leads to its hardening. The goal is to uncover molecular pathways that could be targeted with pharmaceutical treatments.
A mathematical modeling study suggests that removing fallopian tubes during other abdominal surgeries can lower ovarian cancer incidence by five percent. The approach could also reduce total healthcare costs in Germany, with estimated annual savings of over €10 million.
Researchers tracked cfDNA levels before, during, and after colorectal cancer surgery, revealing significant increases associated with age, comorbidities, and surgical manipulation. The study suggests that cfDNA could serve as a non-invasive biomarker to monitor patient outcomes and evaluate surgical effectiveness.
A new study found a significant increase in firearm-related hospitalizations during the COVID-19 pandemic, with rates 34% higher than predicted pre-pandemic trends. The gap was largest for Black patients, children, and those covered by Medicaid, who experienced rates 44%, 46%, and 41% higher, respectively.
Researchers developed a method to detect H3K27M-mutant droplets from circulating tumor DNA in cerebrospinal fluid, enabling early diagnosis and treatment of leptomeningeal disease. This approach improved survival rates for patients with diffuse midline gliomas.
A new analysis reveals that surgery for sleep apnea may lower the risk of motor vehicle accidents compared to using a CPAP device or receiving no treatment. Patients with untreated sleep apnea had a 21% higher odds of accidents, while those undergoing surgery had 45% lower odds.
A systematic review and meta-analysis of over 15,000 patients found that exercise and nutritional enhancement were the most promising components of prehabilitation, reducing complications and length of hospitalization. The study's lead author notes that prehabilitation is promising but still unclear how to implement it across hospitals.
The phase 3 KATHERINE clinical trial found trastuzumab emtansine to be an effective adjuvant treatment for high-risk HER2-positive breast cancer patients, reducing the risk of death or invasive disease by 46% and improving survival. The study showed consistent benefits across patient subgroups, supporting T-DM1 as a new standard of care.
A new study by Mass General Brigham investigators found that Black people were less likely than non-Black people to undergo metabolic and bariatric surgery, even though both groups were equally likely to discuss it with health care providers. Men were also less likely to discuss and receive MBS than women.
Research led by University of Pittsburgh scientists found that exposure to long-wavelength red light reduces blood clots in humans and mice. The study's findings have the potential to reduce deaths and disabilities caused by blood clots worldwide.
A recent study has explored a new imaging approach that uses swept-source optical coherence tomography to visualize the upper airway with high precision. By integrating computational fluid dynamics, researchers were able to identify areas of turbulence and pinpoint obstruction sites, leading to more accurate diagnoses and treatment pla...
The Wake Forest Institute for Regenerative Medicine is part of a major undertaking to bring together experts from around the country to develop vision-restoring whole eye transplants. The project, valued at up to $56 million, aims to overcome technical, biological, and immunological hurdles in whole eye transplant.
A systematic review of 384 studies found that only about one in five health care integrations leads to improved value of care delivery, primarily due to better care management processes. Hospital charges increased with integration, and quality of care showed reduced quality or no change in nearly 77% of the studies.
A cohort study found a decrease in localized invasive breast cancer and regional invasive breast cancer since the 2009 guideline changes, but no decrease in advanced cancer stages. Further research is needed to understand these trends.