Researchers discovered that high-dose vitamin B3 can dramatically extend survival in mice with NAXD deficiency, a devastating genetic disease. The study identifies dozens of other genetic conditions potentially responsive to vitamin therapy.
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A UCalgary study found that adding high doses of vitamin B3 to the treatment plan may help rejuvenate compromised immune cells to kill tumour cells. The clinical trial showed promising results, with 82% of participants free of cancer progression at six-months.
A cohort study suggests nicotinamide reduces skin cancer risk, with greatest effect seen after initial skin cancer diagnosis, indicating potential chemopreventive properties of the vitamin B3 derivative
Researchers found that supplements of B vitamins B6, B9, and B12, as well as choline, slowed down damage to the optic nerve in glaucoma. This was observed in experiments on mice and rats with glaucoma, where eye pressure was left untreated.
Researchers found that biotin supplementation reverses neurotoxicity in human nerve cells, improving mitochondrial function and reducing cell loss. Biotin metabolism was identified as a modifier of manganese-induced neurodegeneration, offering potential therapeutic strategy for Parkinson's disease
A recent study by Cleveland Clinic researchers discovered a connection between elevated niacin levels and an increased risk of heart disease. The study found that high levels of 4PY, a breakdown product from excess niacin, were strongly linked to the development of heart attacks and strokes.
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Researchers from UC Davis School of Medicine and MIND Institute found that imbalances in folic acid and vitamin B12 can alter brain development in mice. High folic acid intake, even within recommended guidelines, may cause neurodevelopmental issues in offspring.
Researchers found that breast cancer cells rely on vitamin B5 to grow and survive. In a study published in Nature Metabolism, scientists discovered that limiting vitamin B5 intake slowed the growth of breast cancer tumours in mice.
Scientists have detected uracil and nicotinic acid in asteroid Ryugu samples collected by the Hayabusa2 spacecraft. The discovery suggests that important building blocks for life were created in space and delivered to Earth via meteorites, supporting current theories on the source of nucleobases.
A new study found that people taking high doses of folic acid were 1.5 times more likely to get COVID-19 and 2.6 times more likely to die from the virus compared to those not on folic acid supplements. Methotrexate, an antifolate drug, mitigated this negative impact when given with folic acid.
Research at the University of Reading found that high-dose Vitamin B6 supplementation reduced feelings of anxiety and depression in young adults. The study links Vitamin B6 to its calming effect on the brain, which may help alleviate mood disorders.
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Researchers found that vitamin B complex supplementation improved blood glucose regulation and kidney function in children with type-1 diabetes. The study suggests that simple supplementation may be a safe and cost-effective strategy for early protection of kidney function.
Researchers found that vitamin B supplements nearly reversed negative effects on heart rate, white blood count, and lymphocyte count in healthy non-smokers exposed to fine particle pollution. The findings suggest a potential preventive pharmacological intervention using B vitamins to contain air pollution health effects.
A study published in HortScience confirms that sweet potato leaves are a good source of vitamins, particularly vitamin B6. The research found that young leaves contained the highest levels of ascorbic acid, while mature leaves provided significant amounts of vitamin B6.
Women with high DDT levels and sufficient B vitamin intake had a 42% greater chance of early miscarriage than those with lower DDT levels. However, women with high DDT and low B vitamin levels took nearly twice as long to conceive.
A new article published in the Journal of Dietary Supplements explores a potential cost-benefit analysis tool that shows daily use of certain dietary supplements, specifically omega-3 fatty acid or B vitamin supplements, can result in reduced odds of experiencing costly medical events. According to the study, high-risk adults over 55 w...
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Researchers found that vitamin B supplements lowered stroke risk in all studies, with some benefit even when taking folic acid. However, the severity of strokes and risk of death from stroke were not affected by supplement use.
Researchers discovered that immune cells use vitamin B products to recognize bacterial infections, triggering an immune response. This finding opens up potential targets for improving treatments or developing a vaccine for tuberculosis.
A team led by USC scientists has identified long-hypothesized vitamin B deficient zones in the ocean using a new analytical technique. These 'vitamin deserts' may inhibit phytoplankton growth and affect the ocean's food chain. The discovery could lead to complex interactions among microbial populations.
A new study suggests that vitamin B and omega-3 supplementation may not prevent cancer recurrence after heart attack or stroke. Women receiving omega-3 supplements were found to have a higher risk of cancer compared to placebo groups.
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A recent JAMA commentary suggests vitamin B therapy can still lower stroke risk, particularly in patients with good renal function. However, the authors argue that clinical trials overlooked the role of vitamin B12 and renal failure, which can affect treatment efficacy.
A study published in JAMA found that high-dose vitamin B therapy worsened kidney function and increased heart attacks and strokes in people with diabetes and kidney damage. However, the treatment did lower homocysteine levels, a risk factor for coronary heart disease.
A new study from Johns Hopkins Medicine found that extended-release niacin, a B vitamin, offers no extra benefits when combined with traditional cholesterol-lowering therapy in seniors already diagnosed with coronary artery disease. Blood cholesterol levels improved, but arteries did not show significant changes.
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A clinical trial by UC San Diego found that high-dose vitamin B supplements did not impact cognitive decline in Alzheimer's patients, despite lowering homocysteine levels. Symptoms of depression were more common in the high-dose group.
A study found that high-dose vitamin B supplementation had no beneficial effect on cognitive decline in individuals with mild to moderate Alzheimer's disease. However, the treatment did lower homocysteine levels, and symptoms of depression were more common in those who received the supplements.
Researchers developed two new southernpeas, WhipperSnapper and GreenPack-DG, with improved characteristics. These peas offer nutrient-rich benefits, pleasing textures, and attractive colors, making them suitable for various applications, including fresh consumption and processing into frozen pea products.
A recent study found that low folate levels and a common mutation in the MTHFR gene may lower the risk of bowel cancer. People with blood levels of folate between the highest and lowest were almost twice as likely to develop the disease compared to those at either extreme.
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A new study finds that adequate daily folic acid intake before pregnancy can reduce neural tube defects (NTDs) by up to 70%. The March of Dimes advocates for increased folic acid fortification in grain foods, particularly among Hispanic populations.