Articles tagged with Ova
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at University of Oregon and Bowdoin College found that a single night with a New York male nematode can reduce the lifespan of females by half. The study suggests that males' sperm, which compete with other sperm for egg access, are highly successful fathers but make poor mates.
A recent study led by the Ginemed fertility clinic found that sperm in the first fraction of ejaculate are more numerous, move faster, and have better DNA integrity than those in the second phase. This discovery could lead to improved fertilization rates and embryonic development.
Researchers at the University of Leeds are conducting a clinical trial to explore the benefits of using hyaluronic acid, a common moisturizer ingredient, to improve IVF success rates in the UK. The trial aims to determine if this method can help select the best quality sperm for injection into an egg.
Researchers at NIH solved a mystery about ovarian cell origins and discovered how these cells share information during development. This new understanding may help identify causes of conditions like premature ovarian failure and polycystic ovarian syndrome.
The honeybee queen uses polyandry to mate with multiple drones and recombination to maintain genetic variation. High recombination rates help the colony adapt to environmental changes.
In a study on flowering plants, researchers have discovered a novel cell-elimination system based on an unusual cell fusion. Successful fertilization triggers cell fusion between the persistent synergid cell and the endosperm, leading to inactivation of the persistent synergid cell.
A rare Caribbean coral species has been successfully bred and raised in the lab, providing a rare glimpse into its procreation process. The research could aid future conservation efforts by increasing genetic diversity and helping populations adapt to climate change.
A new species of fanged frog has been discovered, giving birth to live tadpoles through internal fertilization, a rare reproductive method among frogs. The frog's unique behavior is just one example of the island's incredible biodiversity and adaptive radiation of species.
A Northwestern University-led team uses cutting-edge technology to capture images of zinc sparks in egg cells, revealing a crucial role for zinc in regulating biochemical processes. The study's findings could improve in vitro fertilization methods by identifying high-quality fertilized eggs.
A recent study has clarified how proteins influence the direction of egg transportation in the fallopian tube, a crucial component of the reproductive system. Researchers found that protein Celsr1 is essential for proper transportation by controlling cell shape and ciliary movement.
A single mutation in the beta-catenin gene can lead to abnormalities in sexual organ morphology, making natural reproduction impossible. The study found that this mutation affects specific tissues, causing malformations that prevent successful reproduction.
Researchers at the University of Gothenburg have discovered a signaling pathway in granulosa cells that plays a key role in enabling immature eggs to survive. This mechanism serves as a biological clock monitoring the onset of menopause, allowing the granulosa cells to decide when eggs will begin to grow and when they will die.
Researchers have successfully developed a synthetic version of the sperm protein PAWP, which induces calcium oscillations and oocyte activation in human and mouse eggs. This breakthrough raises hopes for improved IVF success rates and better understanding of fertilization events.
Ovarian cancer cells use mesothelial cells to spread through the body via fibronectin secretion. The study suggests that mesothelium is an active participant in the spread of ovarian cancer.
A study finds that the 'Three-Parent Baby' method, which involves combining a healthy egg cell with a defective one, may pose health risks to offspring if mitochondria from different mothers are present. Researchers propose a solution by analyzing and aligning mitochondrial DNA haplotypes before transfer.
Researchers have uncovered a key biological interaction that occurs during fertilization, identifying the protein in the zona pellucida that sperm latch onto. The study found that ZP2 is essential for sperm binding, and its absence leads to sterility in female mice.
Scientists discovered that the selection process of immature eggs is connected to segments of DNA known as transposable elements. A drug called AZT may enhance the quality and number of eggs by altering jumping gene activity in immature eggs.
A German-Danish team of researchers found that endocrine-disrupting chemicals interfere with human sperm function, changing swimming behavior and triggering digestive enzyme release. The study suggests these chemicals may contribute to widespread fertility problems in the Western world.
A new study found that ovarian cancer cells become more aggressive and proliferate faster when adhering to soft tissues compared to stiffer environments. The research team used novel techniques to measure cell forces, revealing a three-fold increase in traction forces on soft surfaces for metastatic cells.
Scientists have identified a single protein, Juno, that pairs with Izumo on the surface of the egg to initiate fertilization. The discovery may lead to improved fertility treatments and new contraceptives by understanding the essential interaction between sperm and egg, which is crucial for mammalian life.
New research reveals farmed salmon are as fertile as wild salmon and can invade wild gene pools, posing threats to native populations. The study suggests that sterilization of farmed salmon could be a viable solution to mitigate this threat.
The Baltic Sea's unique stratification affects the fate of fish stocks, with different species occupying distinct salinity layers. This research highlights the importance of considering regional conditions in fisheries management, as individual stocks do not necessarily benefit from each other.
A new method for detecting genetic defects in egg cells could significantly increase the success rate of IVF by identifying chromosomal abnormalities and DNA sequence variations associated with genetic disorders. The approach uses whole-genome sequencing of individual egg cells, offering a safe, accurate, and low-cost solution.
University of East Anglia researchers found that female salmon and trout eggs prefer their own species' sperm for fertilization, even when given a simultaneous choice. The preference is driven by the ovarian fluid surrounding the egg, which contains a chemical signal that guides the sperm towards the egg.
A study found that frozen sperm taken directly from testicles is just as effective as fresh sperm in helping couples conceive through IVF. The type of facility where sperm is taken and its distance from the IVF laboratory have no bearing on pregnancy outcomes.
A study comparing mortality and fertility patterns among wild apes and monkeys to humans shows that human females are unique in living beyond their childbearing years. Half of women experience menopause by age 50, and fertility declines earlier than the rest of the body.
Male guppies develop genital claws to increase sperm transfer during mating, with a study showing clawed males transferred up to three times more sperm than declawed males. This adaptation suggests sexual conflict between the sexes played a role in the diversification of the fish's genitalia.
Researchers at RIKEN Center for Developmental Biology successfully cloned mice using a drop of peripheral blood from its tail. This method uses white blood cells, which allow for repeated sampling with minimal risk to the donor mouse. While not surpassing the success rate of cumulus cells, this technique demonstrates a promising altern...
A new study has found that the directed in vitro technique, ICSI, may increase the risk of insulin resistance among children. The study used metabolomics to assess the risk of developing obesity and metabolic syndrome, finding significant differences in 38 metabolites between ICSI and non-ICSI conceived children.
A clinical study found that kisspeptin effectively induces egg maturation in women undergoing IVF treatment, reducing the risk of ovarian hyperstimulation syndrome. The hormone triggers natural reproductive hormone release, resulting in healthy babies.
Female southern bottletail squid consume male ejaculates, using nutrients for egg growth, and target larger females to minimize consumption. This strategic behavior affects males' chances of fertilizing eggs.
Researchers at Carnegie Institution find that adult mice ovaries lack germ-line stem cells for egg production, debunking previous claims of continuous follicle turnover and resupply by adult stem cells. The study uses lineage-tracing technique to show primordial follicles are highly stable, with no detectable stem cell activity.
Researchers found that fetuin-B plays a crucial role in regulating the hardening of the zona pellucida, ensuring fertilization capacity. The discovery has potential therapeutic implications for infertility treatment.
A Northwestern University study has developed a pioneering biophotonics technology to detect ovarian cancer by analyzing cells from the cervix or uterus. The partial wave spectroscopic microscopy technique shows diagnostic changes in these cells even when they appear normal under a microscope, offering a potential breakthrough in early...
A team from Wake Forest Baptist Medical Center's Institute for Regenerative Medicine has developed engineered ovaries that can sustainably release sex hormones estrogen and progesterone. The bioartificial ovary could potentially replace hormone drugs, offering a more natural approach to hormone replacement therapy.
A recent study found little support for legal controls on cross-border fertility treatment in the UK. However, health professionals emphasize the importance of checking overseas clinics to ensure they meet UK standards. The research team also notes that many patients have reported receiving better quality care abroad.
Researchers at UC Davis have identified the essential role of Rnf212 protein in chromosome crossovers, a process vital for sexual reproduction. The study found that Rnf212 defines where crossovers occur, potentially reducing fertility and leading to chromosomal diseases.
Researchers from NYSCF and CUMC developed a technique to transfer human egg cells' nuclei, eliminating the inheritance of mitochondrial diseases. This method demonstrates permanent elimination of mitochondrial DNA, preventing future generations from developing these devastating diseases.
Researchers have successfully transferred the nucleus of a healthy egg cell into an egg cell with mutant mitochondrial DNA, effectively eliminating the disease-causing genetic material. The technique has significant implications for preventing mitochondrial disorders, which affect approximately 1 in 10,000 people worldwide.
The study reveals that removing the worm's germ cells triggers production of dafachronic acid, activating microRNAs that promote longevity. This discovery adds to our understanding of how longevity is regulated.
Research found that injured coral colonies in The Bahamas still produced low numbers of eggs four years after damage, and sperm-producing factories were also scarce. This suggests that damaged corals may divert resources away from reproduction towards growth and injury repair.
A study by Bielefeld biologists found that male bushcrickets determine the timing of sperm transfer, even when they have 'hopped off' after mating. The researchers suggest that females can influence fertilization by consuming a protein-rich mass, but males control the overall process.
Researchers have discovered that the majority of demethylation occurred earlier than previously thought, revealing key insights into methyl group removal. The study identifies regions of DNA that avoid demethylation, potentially explaining how environmental information can be transferred from parent to offspring.
Researchers have discovered that putrescine water can increase the viability of egg cells in women over 30 by inhibiting chromosomal defects. The compound, naturally produced in mammals during ovulation, has been shown to reduce defective eggs by over 50% in older mice.
Researchers at OHSU have successfully demonstrated a new gene therapy method that can replace mutated mitochondrial DNA with healthy copies in human cells. This breakthrough has the potential to prevent devastating diseases passed from mother to infant.
New research reveals that highly metastatic ovarian cancer cells are softer than less aggressive ones, suggesting cell stiffness as a valuable biomarker. This discovery could aid in the development of optimal chemotherapies for various types of cancer.
Researchers at Wake Forest Baptist Medical Center have made a breakthrough in helping infertile, premenopausal women produce enough eggs to become pregnant. By stimulating ovarian cell production using an in vitro rat model, they were able to generate early-stage eggs that could be fertilized.
Melbourne researchers have discovered a new way to protect female fertility by targeting two proteins that cause egg cell death. The study found that blocking the activity of PUMA and NOXA can prevent damaged eggs from dying, potentially maintaining fertility in women undergoing cancer treatment.
Researchers found that blocking the activity of PUMA and NOXA proteins may lead to new strategies to protect women's fertility. The study also showed that missing these proteins can provide protection against radiation damage, potentially delaying menopause and prolonging female fertility.
Researchers found that eggs that don't fertilise due to defective PLCz protein can be treated with human PLCz, initiating fertilisation and improving pregnancy chances. The study strengthens potential use of PLCz in treating male infertility.
A U of S-led team discovered a protein in semen that prompts ovulation by acting on the female brain, found to be the same molecule as nerve growth factor regulating nerve cell growth and survival.
A new study by Syracuse University scientists found that slower and/or longer sperm outcompete their faster rivals in fruit fly reproduction. The research, published in Current Biology, used genetically altered fruit flies to observe sperm in real-time inside the female reproductive tract.
A new genetic study suggests that ovaries can form new eggs throughout adulthood, increasing the number of oocytes with age. This finding contradicts the long-held assumption that females are born with a fixed number of eggs and supports postnatal oocyte renewal in mammals.
Researchers sequenced 91 human sperm from one man, revealing the whole-genome sequence and degree of genetic mixing, with implications for studying cancer, infertility, and other disorders. The study provides a detailed view of recombination in individual sperm, allowing for diagnosis and detection of potential problems.
Researchers at Durham University have identified a key gene involved in sperm-to-egg binding, enabling fertilization in mammals. The discovery highlights the importance of cumulus cells surrounding eggs and suggests potential avenues for improving IVF treatment effectiveness and developing new contraceptives.
Researchers at UC Davis have discovered a crucial enzyme system that regulates chromosome pairing during meiosis, ensuring precise genome sorting and development of healthy sperm and eggs. The discovery could lead to insights into fertility, miscarriages, cancer, and developmental disorders.
Researchers discovered that ovastacin, an astacin family member, cleaves the ZP2 protein in the zona pellucida matrix surrounding eggs. This proteolysis blocks additional sperm binding, preventing polyspermy and ensuring embryonic development. Ovastacin's function is crucial for single fertilization.
Researchers discovered that sperm only react to changes in calcium concentration, not the concentration itself, allowing them to maneuver even in high calcium environments. This calculation enables sperm to follow chemical gradients and navigate towards eggs.
A team of researchers at the University of Gothenburg has identified a key molecule, Cdk1, responsible for initiating the maturation of mammalian eggs. This discovery could lead to an increased rate of successful IVF treatments for women struggling with egg maturation issues.
Researchers from the Caesar Research Centre in Bonn have discovered that sperm do not function like olfactory cells and cannot detect smells. The 'Lily of the Valley phenomenon', which suggested a role for scents in fertilization, is now considered a laboratory artefact.