Researchers at Kyushu University develop a new tissue-clearing reagent, SeeDB-Live, enabling repeated, reversible, and real-time imaging of living brains at greater depth and clarity. This breakthrough allows scientists to visualize neural activity in living mice and brain slices, offering new insights into brain dynamics and function.
A new study found that extensive wildfires in the LA area caused changes in firefighters' immune systems and inflammatory response pathways. The research identified 60 changes in serum proteome, affecting various bodily functions.
A Kobe University study found that metformin reduces copper and iron levels and increases zinc levels in patients with type 2 diabetes. This suggests a possible mechanism for the drug's beneficial effects beyond lowering blood sugar levels.
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A new study found that chronic cannabis use, whether smoked or consumed as edibles, is associated with significant cardiovascular risks. People who regularly used marijuana had reduced blood vessel function comparable to tobacco smokers.
Researchers detected elevated PFAS levels in dogs and horses from Gray's Creek, NC, with horses showing lower concentrations. The study highlights the importance of horses as sentinel species for monitoring PFAS exposure.
Researchers found that women with prediabetes after pregnancy had aberrations in their early pregnancy blood serum metabolomic profile, including higher concentrations of small HDL particles. These metabolic changes predicted prediabetes at postpartum and were associated with increased risk of type 2 diabetes.
A new study published in Vector-borne and Zoonotic Diseases demonstrates that the serum of white-tailed deer blood is lethal to the Lyme disease bacterium, Borrelia burgdorferi. The researchers hope this discovery may lead to new strategies for preventing and treating Lyme disease.
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Researchers developed predictive models using serum microRNAs to identify patients at risk of requiring early palliative care. The study used serum samples from 178 patients with various types of cancer and found that miRNA-based models had higher accuracy than clinical models in predicting referral to a palliative care unit.
A new study from Edith Cowan University found that a single bout of exercise can significantly suppress tumour growth in people with late-stage prostate cancer. The researchers observed increased levels of anti-cancer myokines after high-intensity exercise, which helped fight cancerous cells and stimulated anti-cancer processes.
Two studies found that cigarette smoke and e-cigarette vapor have similar cardiovascular effects due to airway irritation. This irritation can lead to vascular damage and impaired blood vessel function. The research suggests that dual product use may be worse than single product use, highlighting the need for stricter regulations.
A recent study found that alligators in the Cape Fear River basin have elevated levels of PFAS chemicals in their blood serum, leading to clinical and genetic indicators of immune system effects. The research team detected a significant association between PFAS exposure and autoimmune-like phenotypes in the affected alligators.
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A study by Goethe University Frankfurt found that antibodies against Omicron variants BA.1 and BA.2 decline rapidly, even after a second vaccination or booster shot, offering limited protection against infection.
A new study from Oregon Health & Science University found that people infected with SARS-CoV-2 develop durable immunity against variants for at least 11 months. The research suggests that immune protection may endure long-term, potentially reducing the need for vaccine booster shots.
A new transistor-based technology has been developed to quantify SARS-CoV-2 neutralizing antibodies in blood serum and test the efficacy of new vaccines. The device allows for fast and real-time analysis, reducing response times and costs.
A new study finds that breakthrough infections following vaccination and natural infection followed by vaccination provide roughly equal levels of enhanced immune protection. Researchers at OHSU found that both groups generated greater levels of immunity compared to those who were vaccinated with no infection.
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A new study suggests that breakthrough infections generate 'super immunity' to COVID-19, providing a robust immune response against the delta variant and potentially other variants. The study found that antibodies generated from breakthrough cases were 1,000% more effective than those from vaccinated individuals.
A new study by OHSU researchers found that blood serum from vaccinated or infected individuals shows significantly reduced defense against two widely circulating SARS-CoV-2 variants. The findings emphasize the importance of vaccinations combined with maintaining public health measures to cut off the spread of the virus.
Researchers from Peter the Great St.Petersburg Polytechnic University and Tsinghua University created a dynamic light scattering method to determine immune complex sizes in blood serum. The new method can detect diseases, such as autoimmune disorders and cancer, by analyzing changes in immune complex concentrations.
Researchers at Osaka University found that smoking habits change the levels of α-klotho and FGF-21 in blood serum, which are linked to aging. These changes suggest a metabolic disorder and may contribute to accelerated aging in smokers.
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A study found that newborns with low blood sodium consumed more dietary sodium and weighed more than their peers. The researchers concluded that very low serum sodium in pre-term and new-born infants is a significant contributor to long-term sodium intake, a key marker for obesity.
Researchers at PNNL have identified nearly twice as many proteins in human blood serum as previously known, including low-abundance proteins that play crucial roles in cell signaling. The study provides a significant advance in understanding the proteome of blood serum and its potential applications in disease diagnosis.