Researchers report that dupilumab substantially decreases exacerbation frequency and improves lung function as well as symptom burden in COPD patients with type 2 inflammation. The study's findings are promising for these patients, who have a high risk of exacerbations.
SourceUniversity of Alabama at Birmingham·JournalNew England Journal of Medicine·TypeExperimental study·DateMay 20, 2024
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A new study by Columbia University researchers identifies ferroptosis as the major cell death mechanism underlying COVID-19 lung disease. This discovery offers hope for improving treatment outcomes and combating life-threatening cases of the disease.
SourceColumbia University·JournalNature Communications·TypeObservational study·DateMay 20, 2024
A phase 3 trial found that pamrevlumab did not significantly improve lung function in patients with idiopathic pulmonary fibrosis. The study's results underscore the need for effective treatments to slow disease progression and improve patient outcomes.
Researchers at Harvard Medical School analyzed 370,000 participants to find that removing race from lung function tests would shift disease severity categorization across patient populations. This could lead to more white and Hispanic people being reclassified as having less advanced illness.
SourceHarvard Medical School·JournalNew England Journal of Medicine·TypeData/statistical analysis·DateMay 19, 2024
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
A world-first clinical trial found that finding and treating people with undiagnosed asthma or COPD improves their health and reduces healthcare visits. The study, which involved 508 patients, showed that those treated by a lung specialist and educator averaged fewer healthcare visits and improved symptoms compared to usual care.
SourceThe Ottawa Hospital·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateMay 19, 2024
A study led by BCNatal and UPF found that growth-restricted fetuses have differences in lung vascular resistance, which can be normalized with extra oxygen. The research uses artificial intelligence techniques to analyze fetal blood flow and predicts the development of respiratory health problems later in life.
SourceUniversitat Pompeu Fabra - Barcelona·JournalScientific Reports·TypeExperimental study·DateMay 17, 2024
Researchers developed CT-Derived Functional Imaging, a software program that calculates lung volume changes and blood mass without contrast dye. The technology has improved diagnoses for up to 30% of patients who couldn't tolerate contrast dye, and also benefits all patients with lung issues such as COPD and cancer.
A new COVID-related syndrome, MDA5-autoimmunity and Interstitial Pneumonitis Contemporaneous with COVID-19 (MIP-C), has been identified in patients with severe lung scarring and autoimmune diseases. The syndrome was discovered through a retrospective observational study by UC San Diego researchers and UK colleagues.
SourceUniversity of California - San Diego·JournalThe Lancet·DateMay 9, 2024
Researchers discovered that IL-6 signaling in CD4-positive T cells promotes pulmonary hypertension development and progression. Treating mice with IL-6 inhibitors improved symptoms and decreased damage to the lungs and heart.
SourceNational Cerebral and Cardiovascular Center·JournalProceedings of the National Academy of Sciences·DateMay 8, 2024
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Researchers found that iron is a regulator of energy usage by immune cells in the lungs, which can help treat asthma and other allergic diseases. Blocking or limiting iron uptake may reduce asthma severity.
SourceKeck School of Medicine of USC·JournalScience Translational Medicine·TypeExperimental study·DateMay 8, 2024
A comprehensive study by University of Technology Sydney researchers confirms CPAP therapy's safety without adverse effects on the respiratory system. The study uses computational modeling to assess airflow velocity and shear stress, providing reassurance for patients.
SourceUniversity of Technology Sydney·JournalRespiratory Physiology & Neurobiology·TypeComputational simulation/modeling·DateMay 7, 2024
Researchers at Oregon State University have developed a novel device that can improve the delivery of gene therapy for patients with inherited lung diseases such as cystic fibrosis. The device uses aerosolization technology to carry messenger RNA to patients' lungs, reducing shear stress and improving precision.
SourceOregon State University·JournalACS Nano·TypeExperimental study·DateMay 6, 2024
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A Purdue University researcher has received a $2.4 million NIH grant to develop novel inhalation therapeutics for resistant lung infections, which have established resistance to antimicrobial drugs and affect over 2.8 million individuals annually in the US, resulting in more than 35,000 deaths.
SourcePurdue University·JournalPharmaceutics·DateMay 6, 2024
Researchers found PLS occurs significantly more frequently in unequal AB0 settings, leading to haemolysis and anaemia in patients. Blood group A patients with O transplants are particularly at risk.
SourceMedical University of Vienna·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateMay 2, 2024
Researchers at Johns Hopkins Medicine have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many times, a hallmark of cancer cells. The findings reveal what goes wrong when a group of molecules and enzymes trigger the cell cycle, leading to cancer development.
SourceJohns Hopkins Medicine·JournalScience·DateMay 2, 2024
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
A new study found that progressive lung abnormalities in smokers are associated with increased frequency and severity of acute respiratory diseases, highlighting the need for closer monitoring and earlier intervention.
SourceRadiological Society of North America·JournalRadiology·DateApr 30, 2024
A Swedish study published in JAMA Network Open found that over one million newborns were given unnecessary antibiotics for suspected sepsis despite a reduction in sepsis cases. The researchers argue that the treatment burden is too high, suggesting potential to reduce antibiotic use.
SourceUniversity of Gothenburg·JournalJAMA Network Open·TypeObservational study·DateApr 26, 2024
Researchers at UCSF have identified laryngeal and tracheal neuroendocrine cells that sense water and acid in the upper airway, triggering a cough reflex. The discovery could lead to interventions to prevent pneumonia and treat certain types of chronic cough.
SourceUniversity of California - San Francisco·JournalScience·DateApr 18, 2024
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
A new study found that offering stop smoking support alongside lung cancer screening can significantly increase quit rates among high-risk individuals. Up to half of those who attend for lung cancer screening currently smoke, and dedicated funding is urged to provide this essential support.
SourceUniversity of Nottingham·JournalEuropean Respiratory Journal·TypeObservational study·DateApr 18, 2024
Researchers uncover how tuberculosis infection drives excessive inflammation in the lungs by activating neutrophils. Targeting neutrophils could lead to new therapies for TB treatment, potentially reducing antibiotic-resistant cases.
SourceTrinity College Dublin·JournalInternational Journal of Molecular Sciences·TypeExperimental study·DateApr 16, 2024
A new study published in Thorax reveals that increased physical activity and higher body mass index can help recover early-life lung function deficits, leading to normal values in adolescence. The study analyzed data from over 1,100 children and adolescents aged 4-18 years, identifying four trajectories of lung function growth.
SourceBarcelona Institute for Global Health (ISGlobal)·JournalThorax·TypeObservational study·DateApr 15, 2024
A study of tens of thousands of individuals found that post-TB lung disease is a significant global challenge. TB survivors experience restrictive lung damage and airflow obstruction, reducing their ability to breathe efficiently and increasing the risk of cardiovascular and respiratory diseases.
SourceEuropean Society of Clinical Microbiology and Infectious Diseases·DateApr 14, 2024
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers at Michigan Medicine discovered a pathway that reverses idiopathic pulmonary fibrosis (IPF), a common type of lung scarring. The study found that inhibiting the molecular brake MKP1 is essential for spontaneous resolution of fibrosis, offering new hope for patients with IPF.
SourceMichigan Medicine - University of Michigan·JournalJournal of Clinical Investigation·DateApr 12, 2024
A new murine model of dermatomyositis reveals the underlying immune system involvement in this highly progressive disease. The study identifies key components of the immune system responsible for disease development and suggests potential treatments targeting interleukin-6.
SourceTokyo Medical and Dental University·JournalProceedings of the National Academy of Sciences·DateApr 11, 2024
A team of scientists at Scripps Research and Calibr-Skaggs Institute has developed a lung-targeted drug to stimulate the growth of lung stem cells. The new findings provide a biological proof of concept for activating regenerative pathways and restoring damaged lung tissue.
SourceScripps Research Institute·JournalProceedings of the National Academy of Sciences·DateApr 10, 2024
Scientists have developed a new preventative treatment that can prevent lethal lung injury from the flu by targeting inflammation protein. The drug UH15-38 achieves a balance between shutting down runaway inflammation and allowing the immune system to stop the virus, resulting in increased survival rates.
SourceSt. Jude Children's Research Hospital·JournalNature·TypeExperimental study·DateApr 10, 2024
A newly developed compound called UH15-38 has been shown to safely and efficiently block necroptosis, a key receptor in lung cells causing excessive inflammation and lung damage. The study demonstrates that UH15-38 can prevent influenza deaths even when administered late in the course of an infection.
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Researchers at Murdoch Children's Research Institute have made a breakthrough discovery that suppurative lung disease and wheezing have the same inflammatory profiles despite their differing symptoms. The study found two treatable endotypes of childhood respiratory diseases, with targeted anti-inflammatory treatments showing promise.
SourceMurdoch Childrens Research Institute·JournalMucosal Immunology·TypeObservational study·DateApr 4, 2024
Researchers from Karolinska Institutet show that post-COVID does not mean strict exercise avoidance. Patients with post-COVID can benefit from supervised exercise, with improved fitness and muscle strength found in those who participated.
SourceKarolinska Institutet·JournalJAMA Network Open·TypeRandomized controlled/clinical trial·DateApr 4, 2024
Despite therapy, cystic fibrosis patients still suffer from persistent respiratory infections due to unregulated cell signals. By studying lung cells, scientists found a disruption in TGF-β and Wnt pathways, leading to bacterial docking station formation.
SourceUniversité de Genève·JournalAmerican Journal of Respiratory Cell and Molecular Biology·TypeNews article·DateApr 4, 2024
A new study published in International Journal of Environmental Research and Public Health reveals high levels of silica and other silicates in the lungs of military veterans who have deployed since 2001. This research highlights the importance of controlling particulate exposures in military occupational settings to minimize risk for ...
SourceNational Jewish Health·JournalInternational Journal of Environmental Research and Public Health·DateApr 3, 2024
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
A USC study reveals that SARS-CoV-2 causes a stage of mild symptoms followed by severe inflammation in some patients. The virus exploits two different pathways to interact with immune cells, one leading to inflammation and the other preventing it.
SourceKeck School of Medicine of USC·JournalNature Cell Biology·DateMar 28, 2024
The experts recommend setting standards for carbon dioxide, carbon monoxide, PM2.5, and ventilation rate to ensure adequate indoor air quality in public spaces. A CO2 concentration level of 800ppm is proposed with a focus on removing and diluting human-emitted pollutants.
SourceQueensland University of Technology·JournalScience·TypeCommentary/editorial·DateMar 28, 2024
Researchers at Kyoto University have discovered a signal protein called ERK that plays an active role in causing growing lung tissue to curve. This finding reveals a previously unknown regulatory system governing the development of intricate branching patterns in mouse lungs.
SourceKyoto University·JournalCurrent Biology·TypeExperimental study·DateMar 27, 2024
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
A team of researchers at Weill Cornell Medicine has discovered a critical protein sensor called SEL1L that regulates collagen clearance from tissue. This finding provides new insights into the development of therapeutic strategies for diseases like lung fibrosis, which currently have no effective treatments.
SourceWeill Cornell Medicine·JournalNature Communications·DateMar 26, 2024
Researchers have discovered a new way to inhibit immune cells that drive allergic asthma by targeting the Piezo1 protein. The study found that switching on Piezo1 channels can reduce lung inflammation and alleviate symptoms of airway hyperreactivity in mice with ILC2-dependent airway inflammation.
SourceRockefeller University Press·JournalJournal of Experimental Medicine·TypeExperimental study·DateMar 26, 2024
Researchers found that patients with lung disease have a higher risk of developing heart disease, regardless of age or smoking status. The study, published in Orphanet Journal of Rare Diseases, suggests that Proteinase 3 enzyme may play a key role in this increased risk.
SourceUniversity of Birmingham·JournalOrphanet Journal of Rare Diseases·DateMar 22, 2024
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Scientists have discovered six proteins that can accurately diagnose tuberculosis (TB). The breakthrough study paves the way for a simple blood test to detect the bacteria, which could prevent millions of cases annually. TB is the world's deadliest infectious disease, killing over one million people each year.
SourceUniversity of Southampton·JournalJournal of Clinical Investigation·TypeRandomized controlled/clinical trial·DateMar 22, 2024
University of Calgary researchers found that communication between the lungs and brain triggers symptoms of sickness, changing treatment approaches for respiratory infections and chronic conditions. The study also suggests targeting neurological pathways alongside antibiotics to combat infections.
SourceUniversity of Calgary·JournalCell·TypeExperimental study·DateMar 21, 2024
Artificial intelligence has been developed to spot COVID-19 features in lung ultrasound images, combining computer-generated images with real scans to identify signs of disease. The tool holds potential for developing wearables that track illnesses like congestive heart failure and monitor fluid buildup in patients' lungs.
SourceJohns Hopkins University·JournalCommunications Medicine·DateMar 20, 2024
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
A recent NIH-supported study found that SARS-CoV-2 can damage the heart by triggering inflammation in cardiac macrophages. The research suggests that suppressing this inflammatory response may help minimize cardiovascular complications.
SourceNIH/National Heart, Lung and Blood Institute·JournalCirculation·DateMar 20, 2024
Researchers demonstrate efficacy of airborne ultrasound technology to detect low-amplitude movements produced by vocalizations at the chest surface. The technology allows for contactless mapping of surface vibrations, offering a better window on respiratory health and enabling better diagnoses of respiratory diseases.
SourceAmerican Institute of Physics·JournalAIP Advances·DateMar 19, 2024
Researchers at UVA Health discovered a potential blood test to predict patients with severe COVID-19 who are likely to recover well and those at risk of long-term lung problems. The study found that patients with late-resolving symptoms had fewer immune cells in their blood, correlating with symptom severity.
A new study from the University of Chicago analyzed DNA methylation in tissue samples from former smokers, finding evidence of the body's attempts to defend itself from tobacco smoke. The research team identified new regions associated with smoking and found that DNA methylation varies dramatically across cell types and tissue types.
SourceUniversity of Chicago·JournalAmerican Journal of Human Genetics·TypeData/statistical analysis·DateMar 14, 2024
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
A study published in PNAS reveals that increased concentration of lysolipid can cause severe impacts on lung inflation, leading to respiratory distress. The research identifies frequency dependence and proposes a way to tailor treatment processes for each patient.
SourceUniversity of Minnesota·JournalProceedings of the National Academy of Sciences·DateMar 12, 2024
A new reflex of the vagus nerve helps counteract restricted breathing, while a rare cell type detects airway closure and relays the signal. The discovery provides valuable insight into how the brain and body are connected to monitor and modulate respiration.
SourceHarvard Medical School·JournalNature·DateMar 6, 2024
Researchers discovered that lung cancer cells can persist in the presence of cigarette smoke due to a protein pump called ABCG2, which clears damaging molecules from the cells. This mechanism could also contribute to resistance to pharmaceutical treatments in cancer cells.
SourcePenn State·JournalPLOS ONE·TypeExperimental study·DateMar 6, 2024
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Researchers have designed a candidate drug to target the K-Ras G12D mutation, responsible for nearly half of all pancreatic cancer cases. The molecule permanently modifies the mutation, stopping tumor growth in cancer cell lines and animal models.
SourceUniversity of California - San Francisco·JournalNature Chemical Biology·DateMar 5, 2024
Researchers investigated combining Sacituzumab govitecan with platinum-based chemotherapeutics for triple-negative breast cancer, urinary bladder carcinoma, and small-cell lung carcinoma. The study showed additive to synergistic antitumor effects in vitro and in vivo, with improved outcomes in tumor-bearing animals.
SourceImpact Journals LLC·JournalOncotarget·TypeExperimental study·DateMar 4, 2024
A study by Texas A&M University found that only 9% of older Americans had been vaccinated against RSV prior to this fall and winter. The study also revealed that men were more likely to be vaccinated than women, and those who were vaccinated had higher levels of concern about the disease.
SourceTexas A&M University·JournalHealth Affairs Scholar·DateMar 1, 2024
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Researchers at the University of Pennsylvania have developed a new method to efficiently determine which lipid nanoparticles are likely to bind to the lungs, rather than the liver. This breakthrough enables targeted delivery of mRNA therapeutics beyond the liver, offering new hope for treatments of cystic fibrosis and lung cancer.
SourceUniversity of Pennsylvania School of Engineering and Applied Science·JournalNature Communications·TypeExperimental study·DateMar 1, 2024
A new study found that high-dose inhaled nitric oxide improves oxygenation and reduces mortality risk among critically ill Black patients with COVID-19. The treatment was more effective for Black patients, who have a suppressed nitric oxide system at baseline.
SourceUniversity of Alabama at Birmingham·JournalAmerican Journal of Respiratory and Critical Care Medicine·TypeData/statistical analysis·DateFeb 28, 2024
A research project led by Lobelia Samavati has developed a tool to rapidly and inexpensively diagnose sarcoidosis using a simple blood test. The tool can accurately identify the disease in patients and may reduce the need for invasive diagnostic tests.
SourceWayne State University - Office of the Vice President for Research·JournalAmerican Journal of Respiratory and Critical Care Medicine·TypeExperimental study·DateFeb 28, 2024
The Almodóvar lab is studying the link between HIV and pulmonary hypertension, a condition that increases pressure in lung arteries. By examining the interactions between different cell types and using a humanized mouse model, researchers hope to propose novel therapies to prevent lung diseases in people with HIV.
SourceTexas Tech University Health Sciences Center·DateFeb 23, 2024
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
A low-frequency ultrasonic device has been developed to quickly reduce blood pressure and activate blood gas exchange in the pulmonary system. This technology uses a higher radial mode of vibration, increasing acoustic signal penetration and reducing scattered signals.
SourceKaunas University of Technology·JournalRespiratory Research·TypeExperimental study·DateFeb 22, 2024
Scientists have created a simple blood test to quickly diagnose sarcoidosis, a chronic inflammatory disease. The tool uses a combination of molecular techniques to detect two newly described disease-specific antigen biomarkers.
SourceNIH/National Heart, Lung and Blood Institute·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateFeb 22, 2024
Researchers found that Inuit residents in Nunavik had shorter survival rates for lung cancer compared to Montreal residents, despite similar disease stages. The study attributes this disparity to chronic under-resourcing of healthcare services and lack of Inuit representation in healthcare provision.
SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·TypeObservational study·DateFeb 20, 2024
A new computer model of a human lung is being used to simulate the interaction of radiation with lung tissue at a cellular level. This could lead to more targeted treatments for cancer and reduce damage caused by radiotherapy.
SourceUniversity of Surrey·JournalCommunications Medicine·TypeComputational simulation/modeling·DateFeb 20, 2024
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Researchers at Columbia University School of Engineering and Applied Science have developed a new inhalable therapy that delivers IL-12 mRNA directly to the lungs, demonstrating potential as a tumor suppressor. The therapy uses nanobubbles called exosomes to deliver the mRNA, which kickstarts lung immune cells to fight cancer.
SourceColumbia University School of Engineering and Applied Science·JournalNature Nanotechnology·DateFeb 15, 2024
Researchers have identified macrophages, immune cells that gobble up foreign substances, in the pleural cavity around the lungs. These cells play a crucial role in reducing inflammation and disease during flu infections.
SourceUniversity of California - Riverside·JournalProceedings of the National Academy of Sciences·DateFeb 14, 2024