Articles tagged with Parasitic Diseases
Scientists at the University of Edinburgh made a groundbreaking discovery that could help combat the spread of sleeping sickness. By understanding how parasites communicate with each other, researchers may be able to develop new drugs to disrupt these messages and limit the disease's transmission.
A study published in The Journal of Mammalogy found that female prairie dogs who mate with two or more males rear more offspring than those that mate with only one male. The research, led by John Hoogland, suggests that the benefits of polyandry outweigh the costs for most species of prairie dogs.
Researchers at McGill University Health Centre have identified a target molecule that can block Cryptosporidium parvum's ability to evade the immune system, providing a potential treatment for this deadly parasite. The discovery could lead to an effective treatment for cryptosporidiosis, which affects millions of people worldwide.
Researchers have found a modified version of a common human dietary supplement to be effective in curing lab animals infected with hookworms. The probiotic was found to be safe and potentially lethal to intestinal worms, offering new hope for treating the disease that affects 1.5 billion people globally.
Researchers at UC San Diego School of Medicine have created over 650 new compounds that restore or improve effectiveness against drug-resistant pathogens in animal models. The findings could have major impact in the struggle against antimicrobial resistance, which threatens public health globally.
A study by the University of Manchester team has identified a new pathway regulating immune responses in the gut that can protect against infection. This finding holds promise for developing a protective immune response during parasite infestations, potentially addressing a major public health issue.
Researchers discovered that the Baoulé breed of cattle has a natural tolerance to a deadly parasite, and developed a method to detect different types of trypanosomes. The study aims to preserve the genetic background of the Baoulé breed to develop more resilient cattle breeds.
Research in Missouri ponds suggests that chytrid fungus may also infect invertebrates like insects, providing a new clue to its ecology and transmission. The study found that ponds with chytrid were more similar in certain measures, indicating alternative hosts or reservoirs for the fungus.
Chronic Toxoplasma infection causes mice to lose innate fear of cats, which persists even after parasite clearance and inflammation markers are undetectable. The infection alters the brain's mechanisms underlying fear responses, leading to a lasting behavioral change.
Researchers at the University of Warwick have developed a model of the American foulbrood disease outbreak in Jersey, which helps understand how the disease spreads and simulates various control interventions. The study found that just under half of the infection spread was attributed to transmission by beekeepers between their own hives.
Researchers at UCSF have discovered a link between meal times and daily changes in the immune system. Eosinophils, previously thought to fight parasitic diseases, may actually help invaders, according to the study. This discovery could lead to new strategies for fighting chronic parasitic infection and allergies.
A team of researchers found multiple roundworm eggs in soil samples taken from Richard III's pelvis, indicating a genuine infection. The presence of no eggs in skull soil and few in surrounding grave soil suggests the infection was internal, not from external contamination.
A study found that piglets receive maternal IgA, IgG and IgM antibodies against Cystoisospora suis in the colostrum, which decline after two weeks. High levels of these antibodies are associated with reduced severity of neonatal diarrhoea.
Tiny parasites, known as Mikrocytos mackini, have been found to infect Pacific oysters, causing unsightly green lesions and death. The discovery sheds light on the parasites' reduced metabolism and unique relationship with their host.
A study found that over three-quarters of imported bumblebee colonies tested carried parasites, posing a risk to native bees and honeybees. The researchers argue that producers must improve disease screening and regulatory authorities must strengthen measures to prevent the importation of parasite-carrying colonies.
Researchers at LSU Health Sciences Center have found new modes of transmission and associated behaviors for a parasitic lung infection. New cases are reported in the US, particularly among those who consume raw or undercooked freshwater Asian crabs or native crawfish.
Researchers treated wild mice for a gut worm infection and found that treating one bug allowed other infections to flourish. The study suggests that co-existing infections can compete with each other and alter disease progression.
Researchers have discovered a new approach to control parasitic nematodes by targeting key developmental processes. The study, published in PLOS ONE, identified 22 proteins involved in the transition from third-stage to fourth-stage larvae, offering potential targets for new treatments.
A new study found that adults with depression and certain antidepressant medications are more likely to develop Clostridium difficile infections, a serious and costly hospital-associated infection. Individuals with major depression were 36% more likely to develop the infection than those without depression.
A recent study has found a significant link between certain antidepressants and an increased risk of Clostridium difficile infection. People with major depression were 36% more likely to develop CDI, while the use of mirtazapine and fluoxetine doubled the risk. Researchers stress that the exact cause of this association is unknown.
Researchers found that infection with nematodes reduced body weight by up to 15% in obese mice and lowered fasting blood glucose levels. The study suggests a potential therapeutic effect of nematode infection on metabolic disorders, including inflammatory bowel disease and allergies.
A new genetic analysis of human lice from around the world sheds light on their evolution, disease transmission, and resistance to insecticides. The study's findings suggest that lice can be used as a tool to understand human migration patterns and test ideas about human evolution.
A CU-Boulder study found that ponds with diverse amphibian species have a 78% reduction in parasitic infections, which can cause severe deformities. Greater biodiversity also appears to protect against other diseases, such as Lyme disease and West Nile virus.
A new study reveals that the UK dog population produces an estimated 3.7 billion Toxocara parasite eggs per day, contaminating public environments and posing a risk to human health.
Researchers at the University of Georgia have identified a specific receptor regulating calcium release in the trypanosome parasite, which could lead to new therapies for sleeping sickness. The discovery may also have applications beyond treating this disease, including new treatments for blood clotting disorders.
Researchers found that during a nematode-induced inflammation, the immune system increases cholecystokinin levels, reducing leptin production, which drives defense mechanisms against the parasite. The study suggests a novel mechanism for parasite expulsion in intestinal infections.
African sleeping sickness, caused by a brain-invading parasite transmitted by tsetse flies, can persist in areas with no human cases due to wild animal populations. A new study suggests that targeting humans alone may not be enough to control the disease and that efforts must factor in wild animals.
A new study has identified toll-like receptor 12 (TLR12) as crucial for combating the deadly parasite Toxoplasma gondii. The findings suggest that TLR12 promotes survival in infected animals and could lead to the development of a vaccine against this parasite.
A recent study published in PLOS One reveals that a common diarrhea-causing bacterium triggers an overactive immune response, worsening illness in hospital-acquired infections. Researchers found that activating a protective mechanism involving the PPARgamma pathway can reduce disease severity and be activated by existing diabetes drugs.
Scientists have mapped a weak spot in the parasite that causes African sleeping sickness, providing a promising target for treating the disease. The study uses X-ray lasers to determine the structure of biological molecules, which could lead to the development of a new drug.
A new study reveals that hyperparasitoids exploit plant odours triggered by parasitoid-infected caterpillars, compromising the mutualistic relationship between plants and parasitoids. This complex network of interactions highlights the importance of considering species at multiple trophic levels in ecological functions.
A recent study suggests that fecal microbiota therapy may help pediatric patients with recurrent C. diff. diarrhea, while another study highlights the increased risk of health complications in hospitalized children with CDI, including longer hospital stays and higher mortality rates.
Researchers have successfully unraveled the life cycle of Hematodinium, a single-celled parasite affecting blue crabs. The study provides critical information on transmission and development time, enabling better management and handling practices for wild-caught blue crabs and shrimp farms.
Researchers tracked parasite-induced disease and death in reintroduced wolf packs in Yellowstone National Park, finding that mange did not infect wolves until 2007. The diseases that infected the wolves quickly were all viral, including canine distemper and parvovirus, while mange is a skin infection caused by scabies mites.
Researchers found Hematodinium sp. and its sister species are a major problem for crab fisheries, causing 'bitter crab' disease. The parasites have bacteria-like endosymbionts that increase their chances of survival outside the shrimp, leading to significant damage to infected crustaceans.
The expanding raccoon population in Europe threatens native species and human health with infectious diseases such as rabies and Baylisascaris procyonis. The spread of these illnesses is linked to the raccoon's adaptability, high reproductive potential, and lack of natural predators.
A study published in The Journal of Clinical Psychiatry found that individuals infected with the T. gondii parasite are seven times more likely to attempt suicide. The researchers also discovered that the parasite can cause inflammation in the brain, leading to changes in brain chemistry and potentially contributing to depression.
A University of Oklahoma research team has been awarded a $9.7 million NIH grant to study human diseases associated with aging, osteoporosis and diabetes. The grant will provide significant resources for investigators to pursue structure-based biomedical studies.
Two species of single-cell parasites have acquired new genes that work together to make an essential nutrient, allowing them to exploit their hosts more efficiently. This discovery highlights the importance of horizontal gene transfer in the rapid evolution of these tiny organisms.
A new study published in PLOS Medicine found that public reporting of hospital-acquired infection data led to a significant reduction in C. difficile cases. The study showed a 26% decrease in C. difficile infections after mandatory hospital reporting was introduced in Ontario, Canada.
Researchers at the University of Gothenburg are working on developing substances that can prevent parasites, bacteria, and fungi from producing essential proteins. If successful, this could lead to the development of new drugs for several major diseases, including cancer, parasitic diseases, and bacterial and fungal infections.
A study of over 3,000 dairy herds in England and Wales found that liver fluke infection reduces the sensitivity of skin tests used to diagnose bovine TB. This means infected cattle may not be identified by current surveillance schemes, contributing to the disease's spread.
Researchers found that T cell imbalance increases risk for gastrointestinal infection recurrence, particularly in C. difficile cases. Patients with recurrent infections had higher levels of regulatory and TH17 cells, which could lead to targeted molecular therapies.
A University of Colorado study found that increases in parasite diversity lead to a decrease in the infection success rate of virulent parasites, including one that causes malformed limbs and premature death. Higher biodiversity can help protect against certain diseases by acting as a buffer against virulent pathogens.
A Mayo Clinic study found a significant increase in C. diff infections in children between 2004 and 2009, with 75% of cases acquired in the community. The study also highlights the importance of prevention measures to reduce the spread of this environmental infection.
Researchers have developed a new series of drugs that target the fox tapeworm, which causes rare but life-threatening disease in humans. The drugs, derived from anti-cancer agents, show potential in killing the parasite and treating the disease.
A large multicenter study found that patients with community-onset Clostridium difficile infection have a four times higher risk of colectomy compared to those who developed symptoms in the hospital. Older adults and individuals with severe cases are also at higher risk for CDI-related colectomies.
Academics at the University of Nottingham are recruiting patients with relapsing remitting multiple sclerosis to test the effect of a low dose of the helminth parasite Necator americanus on their immune system. The study aims to prove that hookworms can reduce MS symptoms and prevent relapses.
Research proposes that parasite evolution plays a key role in host sex-biased parasitism and disease expression. Characteristics like morphology and behavior differ between sexes, posing unique challenges for parasites, which may adapt more to one sex than the other.
A recent study by UBC researchers has identified the increasing presence of terrestrial pathogens in marine mammals along the Pacific coast. The team calls for improved surveillance and collaboration to monitor public health implications and reduce land-sea transfer of pollutants.
Fruit flies seek out alcohol to kill off blood-borne parasitic wasps, showing a potential natural remedy for fighting infection. Environmental alcohol protects fruit flies from parasitism, and consuming alcohol leads to death of the wasps.
Researchers found Substance P, a pain transmitter, causes seizures in brain-infected patients; blocking its receptor may provide treatment relief. The study suggests a new approach for managing seizures in these patients.
Researchers discovered Substance P causes seizures in patients with neurocysticercosis (NCC), a parasitic tapeworm infection of the brain. Blocking Substance P receptors may prove effective in treating and preventing seizures in affected individuals.
A study of nearly 15,000 patients found that up to three-quarters of new C. difficile infections were not easily explained by conventional assumptions of ward-based transmission from symptomatic patients. This suggests that current interventions may not be effective in controlling the spread of C. difficile in hospitals.
Research on three-spined sticklebacks reveals that reoccurring infectious diseases influence the frequency of immune genes. This variability helps individuals resist diseases but poses a challenge for organ transplants. In contrast, the variation in human HLA alleles enhances mating choices by providing optimal gene combinations.
Researchers have discovered that toltrazuril can effectively control coccidiosis in piglets, whereas sulfonamides fail to provide sufficient protection. Toltrazuril treatment has been shown to significantly improve health outcomes and reduce diarrhoea in pigs.
A new study found that global warming increases the growth rate of parasites in fish, leading to altered host behavior and potentially devastating effects on fish reproduction. The research also suggests that parasites can manipulate host behavior to seek out warmer temperatures.
Researchers found that antibiotics are not the sole risk factor for community-acquired Clostridium difficile infection and that nursing home residence is a strong predictor of disease severity. The study identified increasing age, higher Charlson Comorbidity index, and lack of antibiotic exposure as predictors of hospitalization.
Fecal microbiota transplants have shown high efficacy in treating recurrent C. difficile infections, with a success rate of 91% in one study. The procedure has also been effective in treating Inflammatory Bowel Disease, particularly when done recurrently. Researchers found that fecal transplant is a safe and effective treatment option ...
A collaborative study by the University of Melbourne and BGI sequenced the draft genome of Ascaris suum, a parasitic roundworm of pigs. The study provides a comprehensive resource to combat ascariasis and other nematodiases, with potential drug targets identified.