Articles tagged with Estrogen
Dr. You's research highlights the effects of endocrine-active chemicals on biological systems, finding altered gene expression in male rats exposed to high levels of genistein and methoxychlor. The study suggests plant-based estrogens can alter the effects of synthetic compounds like pesticides.
Researchers found that estradiol levels changed significantly during exercise for women using transdermal estrogen patches, but returned to normal within thirty minutes. In contrast, other hormones showed no significant changes during exercise with oral or transdermal administration.
A study found that estrogen biases rats to use a place-oriented task strategy faster than those without estrogen. However, response-driven tasks were completed quicker by rats not on estrogen. The research suggests estrogen enhances some forms of learning but impairs others.
A new study suggests that testosterone may play a protective role against stroke in men, while estrogen levels are not linked to stroke risk. The study followed 6,732 individuals over five to eight years and compared serum levels of testosterone and estrogen between men who experienced strokes and those who remained healthy.
Researchers found that women treated with tamoxifen or estrogen had lower levels of myo-inositol in the brain compared to untreated women. The study suggests that both hormones may be neuroprotective and have favorable effects on aging, but further studies are needed to confirm these findings.
A new study suggests that tamoxifen and estrogen may have comparable effects on the brain, with lower levels of myo-inositol found in both groups. This finding challenges previous assumptions about tamoxifen's impact on cognitive function and presents a promising direction for breast cancer risk reduction.
Researchers at UPCI found that several plant extracts interact with estrogen receptors and induce strong estrogenic responses in female rats. The study highlights the need for caution when using these remedies, especially for women with a family or personal history of breast and uterine cancer.
A new study by Eckehard Liske, PhD, confirms the safety and efficacy of RemiFemin in relieving menopausal symptoms. The research shows that standardized herbal supplement works without affecting hormone levels, reducing hot flashes, mood swings, night sweats, and sleeplessness.
Researchers found that estrogen production protects females from cardiac hypertrophy, but not males. By blocking estrogen receptors, female mice developed cardiac enlargement similar to males.
A study found that hormone therapy slows atherosclerosis progression in monkeys with healthy blood vessels. Estrogen was most effective when given at an early stage, suggesting it may be less beneficial for women with advanced arterial disease.
A Mayo Clinic study finds an association between estrogen status and reduced coronary calcium and plaque area, suggesting a potential benefit against heart disease. Estrogen may modulate the calcium content of atherosclerotic plaques, slowing progression of atherosclerosis in women.
A study on female monkeys found that stress can reduce estrogen levels, leading to the development of atherosclerosis and increasing heart disease risk. The research highlights the importance of pre-menopausal behavioral and hormonal conditions for post-menopausal health.
A Stanford study shows that hormone therapy can improve mental health and reduce depression in women experiencing hot flashes, but may have negative effects on those without symptoms. The research suggests that women should discuss their individual risks and benefits with their doctor before making a decision.
Researchers at Lehigh University have discovered a possible cause-and-effect relationship between DHEA and the workings of the body's central nervous system. The study found that DHEA influences gene function through interaction with androgen receptors, potentially contributing to improved neuron survival and cognitive function.
A new study finds that raloxifene, an osteoporosis medication, reduces breast cancer risk by 76% in postmenopausal women with high estrogen levels. Women with low estrogen levels receive no reduction in risk.
A new study analyzing oral contraceptive use among women with epithelial ovarian cancer found a significant association between progestin levels and reduced risk. Women using low-progestin/high-estrogen contraceptives were more likely to develop ovarian cancer compared to those using high-progestin/high-estrogen contraceptives.
A study of 73 postmenopausal women found no significant changes in serum estrogen, cortisol, or follicle stimulating hormone levels after consuming soy protein for up to 6 months. Circulating thyroid hormone levels were modestly increased in those taking the highest dose of soy isoflavones.
A recent study at Duke University Medical Center found that letrozole, a new breast cancer treatment, was more effective than tamoxifen in shrinking tumors and reducing cell division. Patients taking letrozole showed significant tumor shrinkage and underwent fewer mastectomies compared to those on tamoxifen.
A randomized controlled trial found that unopposed estrogen therapy reduced atherosclerosis progression by .0017 millimeters per year in postmenopausal women. The study also showed that cholesterol-lowering drugs had a similar effect when combined with estrogen, suggesting potential benefits for cardiovascular health in women at risk.
Two studies examine the link between sex hormones and coronary artery spasm, finding that estrogen levels during menstruation affect blood vessel function. Automated external defibrillators are also shown to be safe and easy to use by trained laypersons, paving the way for potential home sales.
Researchers at Columbia University Irving Medical Center discovered that estrogen therapy improves consistency in older women, a key indicator of cognitive function. The study, which involved postmenopausal women taking hormone replacement therapy, found that estrogen users performed more consistently than those not taking the hormone.
A University of Michigan study found that female rats exposed to estrogen and cocaine showed increased sensitization, leading to faster craving and lower doses. The effects persisted even after the hormone was removed.
Researchers at the University of Illinois discovered that estrogen regulates fluid reabsorption in the male reproductive tract by triggering a protein involved in sodium transport. This finding suggests that blocking estrogen receptors could provide a new target for developing effective contraceptives for men.
Low levels of estrogen hormones in water may be responsible for the feminization of wild fish, according to a recent study. Researchers found that very low concentrations of estrogenic compounds released from sewage treatment plants were causing intersex and altered sex ratios in aquarium fish.
The study, published in the New England Journal of Medicine, found that estrogen replacement therapy for secondary stroke prevention was not beneficial. The Yale team also discovered a borderline higher risk of fatal stroke among women taking estradiol.
A new randomized, controlled clinical trial found no significant difference in the incidence of stroke or death among postmenopausal women who received estrogen therapy. The study suggests that estrogen should not be prescribed for preventing a second stroke or death in these patients.
Research suggests that estrogen replacement drugs can modify vein function in ways that increase the risk of venous thrombosis. Studies using adult female pigs found that hormone replacement therapies containing estradiol and SERMs altered cellular processes in veins, leading to changes in diameter, relaxation, and coagulation.
Estrogen controls lymphocyte formation and replenishment of the immune system by binding to hormone receptors found only in rare "precursors" within adult bone marrow. This discovery reveals that various kinds of stem cells may differ between fetal and adult life, protecting the fetus's immune system from estrogen-related compounds.
Researchers at the Mayo Clinic found a possible link between estrogen and reduced risk of Parkinson's disease. The study reviewed medical records of female patients with Parkinson's disease to examine the association with menopause type, age, and postmenopausal hormone therapy.
A study found that consuming five or ten grams of ground flaxseed daily for seven weeks reduced blood levels of certain estrogens associated with an increased risk of breast cancer. The researchers believe that lignans in flaxseed may lower estrogen levels by inhibiting enzymes involved in estrogen synthesis.
A new study found that estrogen patches can improve attention and memory skills in women with Alzheimer's disease. The research used estradiol, a type of estrogen shown to have an effect on the brain, and found significant improvements in attention and memory tests.
Researchers found that Raloxifene stimulated the growth of ovarian cancer cell lines, raising concerns about its use in ER+ patients. The study advises caution when prescribing Raloxifene to women with a history of breast cancer and ovarian cancer.
New data from the Nurses' Health Study suggests hormone replacement therapy reduces heart attack risk by 40% in postmenopausal women. However, taking higher doses of estrogen or combination therapy with progestin may increase stroke risk by 30%.
A recent study published by the Mayo Clinic has found that estrogen plays a crucial role in preventing bone resorption in elderly men. The research suggests that estrogen is essential for maintaining optimal bone metabolism in aging men, and highlights the importance of osteoporosis prevention for this demographic.
A low dose of estrogen was as effective as a higher dose in reducing bone turnover and preventing osteoporosis in older women. The study found that women taking 0.25 mg estradiol had no more side effects than those taking a placebo, improving bone health with fewer risks.
A study conducted at Massachusetts General Hospital found that over 90% of young women with anorexia nervosa suffered from significant bone loss. The research highlights the importance of regaining and maintaining a healthy weight in preventing or reducing bone loss.
The Mayo Clinic report concludes that the available data are insufficient to draw definitive conclusions about the use of soy isoflavones as an alternative to estrogen for hormone replacement in postmenopausal women. Randomized, placebo-controlled clinical trials are necessary to address the potential benefits and risks of isoflavone use.
A new study found that premenopausal women are more vulnerable to sudden, serious heart disease during their menstrual cycle when estrogen levels are at their lowest. The research also identified other health risks that worsen the odds for heart disease in young women.
Researchers found that male mice genetically altered to lack estrogen receptors became obese, with up to 170% increase in fat storage. Estrogen was also linked to improved fat burning ability in both males and females, challenging previous understanding of its role in female physiology.
A prospective study of 10,786 Italian women found a 40% lower risk of breast cancer in premenopausal women with the C-2 estrogen metabolism pathway, which produces less active by-products. Lifestyle changes such as physical activity and a low-fat diet high in cruciferous vegetables may shift estrogen metabolism from high-risk to low-risk.
Dr. Sherwin's research suggests that estrogen replacement therapy prevents some of the decline in verbal memory and ability to learn new material in postmenopausal women. This effect has been observed even in women who underwent surgical removal of their ovaries, which led to a sudden drop in estrogen levels.
Reduced estrogen levels caused by stress can lead to atherosclerosis and increased heart disease risk in women. Stress affects estrogen production, causing fatty deposits in arteries and potentially leading to heart attacks and strokes.
A preliminary study suggests that estrogen can effectively boost mood in women experiencing depression during perimenopause. The hormone significantly improved symptoms such as early morning awakening and loss of enjoyment, with relief achieved within three weeks.
A recent study found that older women with high natural estrogen levels are less likely to suffer cognitive decline. The researchers measured free estrogen and loosely bound forms of the hormone, finding a 70% lower risk of cognitive decline in those with the highest levels.
A new study on rhesus monkeys found that those without functioning ovaries performed better on spatial memory tasks than monkeys with intact ovaries. This suggests that the lack of estrogen may protect against age-related decline in certain aspects of spatial memory.
A study published in Neurology found that estrogen had no effect on improving memory and mental functions in postmenopausal women with mild to moderate Alzheimer's disease after a 12-week period. Researchers suggest further trials are needed to determine the effectiveness of estrogen in preventing or delaying the onset of Alzheimer's.
Researchers found that estrogen use reduced cognitive decline in women with e2 and e3 ApoE alleles, but not in those with e4 variants. Estrogen also showed protective effects on carotid wall thickening and atherosclerosis.
Researchers found greater numbers of estrogen receptors on lung cancer cells, suggesting a role for this hormone in enhancing tumor growth. Estrogen was shown to increase cell division and tumor growth in both cultured lung cancer cells and animal models.
A new study of 309 older women found that hormone replacement therapy (HRT) did not slow the progression of heart disease. HRT lowered cholesterol, but this benefit did not translate to a measurable impact on artery narrowing.
A high dose of estrogen administered soon after a stroke can prevent substantial brain damage in laboratory animals, with a 60% decrease in brain cell death. The study builds on observations that postmenopausal women who take estrogen replacement therapy are more likely to survive stroke.
A study led by MGH researchers found that androstenedione supplementation increases testosterone levels in healthy young men, with estrogen levels also rising at both 100 and 300mg doses. Long-term effects of androstenedione on hormone levels and athletic performance are unknown
Researchers found that supplemental estrogen prevented hypertension in 3-month-old female rats with healthy hearts, but not in 17-month-old rats who already had hypertension. The study suggests that estrogen supplementation may be beneficial for women nearing or going through perimenopause, where estrogen levels decline.
Scientists generate mutant mice with disrupted estrogen receptors, resulting in adult female ovaries transforming into male-like cells. This discovery advances our understanding of the action of estrogen and its role in human fertility and cancer.
Researchers found that estrogen can reduce the risk of developing cataracts by up to 77%, with estradiol and estrone showing particular promise. The study used rats with induced ovarian failure to test the effects of different estrogens on cataract development.
A new study suggests that estrogen supplementation in postmenopausal women may slow the progression of periodontal disease, protecting their teeth. The research found that estrogen deficiency and osteopenia/osteoporosis speed oral bone loss following menopause, leading to tooth loss.
Researchers found that methylation of estrogen receptor genes may be linked to atherosclerosis and increased risk of heart disease in women. The study suggests that a genetic shutdown may contribute to the perplexing results of hormone replacement therapy on heart disease.
Researchers found that genetic variation significantly impacts an individual's sensitivity to estrogen, challenging traditional laboratory-animal-based safety tests. The study suggests that genetic makeup should be considered when prescribing estrogen and related hormones for medical purposes.
Researchers found that tamoxifen causes the estrogen receptor to form a unique pocket that changes its response to the drug. New drugs targeting this pocket may offer hope to patients with breast cancer resistant to tamoxifen.
Researchers at Cedars-Sinai Medical Center are launching a clinical trial to assess the impact of isoflavones, found in clover and soybeans, on the human endometrium. The study aims to determine whether these plant compounds can counteract estrogen's proliferative effects and reduce the risk of endometrial cancer.
Biologists at Washington University in St. Louis have discovered that lower estrogen levels allow cytokines to bind to bone cell surfaces, leading to bone destruction. Estrogen replacement therapy may be able to prevent this by increasing decoy receptor proteins, which inhibit cytokine binding.