Articles tagged with Estrogen
A new study found that synthetic hormone estren can build bone in animals without affecting reproductive organs. The researchers tested estren, estrogen, and testosterone in mice with and without sex organs, showing estren's potential to provide a safe form of hormone replacement therapy.
A new study published in the journal Science suggests that estren, a synthetic compound, can build bone and improve bone density and strength without affecting reproductive organs. The findings may indicate a potential alternative to standard hormone replacement therapy for treating osteoporosis in both men and women.
Researchers studying walleye fish in Minnesota waterways find high levels of estrogenic chemicals, linked to reproductive changes. Meanwhile, Puerto Rico aquaculture projects test new offshore cages to minimize environmental impact and promote sustainable fisheries.
Researchers have discovered a promising new treatment that preserves bone mass in both female and male mice without affecting reproductive organs. Estren, a class of compounds called ANGELS, appears to trigger bone-building activities without the side effects associated with sex hormone therapy.
A study of 28 young women found that consuming isoflavone-enriched soy protein supplements for a year did not increase bone mineral density. The researchers assessed the bone mineral content and density of each subject using dual-energy X-ray absorptiometric measurements.
The American College of Physicians' Task Force concludes that combined estrogen and progestin therapy has more likely to cause harm than benefit for most women. The evidence is insufficient to recommend hormone therapy alone or together for preventing chronic conditions in postmenopausal women with hysterectomies.
Researchers found that chemicals in detergents, plastics, and medicines can mimic natural estrogens, disrupting the sexual development of juvenile zebrafish. The study suggests that these compounds can affect not only the reproductive capacity but also sex ratios of fish populations.
A study of 44,241 women found that postmenopausal estrogen-only therapy increases the risk of ovarian cancer by 60%, with a greater risk for those using therapy for 10 or more years. The relative risk was highest for women who used estrogen for 20 or more years.
A national study on estrogen for postmenopausal women was halted after five years, showing a 26% increased risk of breast cancer and no significant cardiovascular benefits. The study found moderate reductions in fracture and colorectal cancer risk, but the risks outweighed the benefits.
A hormone therapy study involving 16,608 women was stopped early due to a 26% increase in breast cancer risk. The study found that the risks of estrogen plus progestin outweighed any potential benefits for heart disease and hip fractures.
The Women's Health Initiative has stopped its trial on estrogen-progestin combination Prempro due to significant increased risk of breast cancer and cardiovascular events. Women taking this medication will continue with regular contacts, exams, and mammograms.
A randomized clinical trial found that exercise reduced estradiol and estrone levels in postmenopausal women, particularly those who lost body fat. The study suggests that exercise may play a role in reducing the risk of breast cancer by lowering estrogen levels in older women.
A long-term study of hormone therapy in postmenopausal women with heart disease found no reduction in heart attack risk and increased blood clot risk. The therapy also showed a higher risk of gallbladder disease requiring surgery.
Research by Wake Forest University professor suggests that hormone replacement therapy can help prevent heart vessel disease when started at the right time. Studies on postmenopausal monkeys and younger women have found a strong link between estrogen therapy and reduced fatty build-up in the heart's arteries.
A new study found that estrogen combined with calcium and vitamin D supplements improved jaw mass and density in postmenopausal women, reducing the risk of tooth loss. The study also showed that estrogen had a significant impact on bone mineral density in other parts of the skeleton.
Researchers at the University at Buffalo found that estrogen can suppress production of pro-inflammatory components, reducing atherosclerosis risk. Estrogen may help explain why women have lower heart disease risk until menopause.
Dr. You's research highlights the effects of endocrine-active chemicals on biological systems, finding altered gene expression in male rats exposed to high levels of genistein and methoxychlor. The study suggests plant-based estrogens can alter the effects of synthetic compounds like pesticides.
Researchers found that estradiol levels changed significantly during exercise for women using transdermal estrogen patches, but returned to normal within thirty minutes. In contrast, other hormones showed no significant changes during exercise with oral or transdermal administration.
A study found that estrogen biases rats to use a place-oriented task strategy faster than those without estrogen. However, response-driven tasks were completed quicker by rats not on estrogen. The research suggests estrogen enhances some forms of learning but impairs others.
A new study suggests that testosterone may play a protective role against stroke in men, while estrogen levels are not linked to stroke risk. The study followed 6,732 individuals over five to eight years and compared serum levels of testosterone and estrogen between men who experienced strokes and those who remained healthy.
Researchers found that women treated with tamoxifen or estrogen had lower levels of myo-inositol in the brain compared to untreated women. The study suggests that both hormones may be neuroprotective and have favorable effects on aging, but further studies are needed to confirm these findings.
A new study suggests that tamoxifen and estrogen may have comparable effects on the brain, with lower levels of myo-inositol found in both groups. This finding challenges previous assumptions about tamoxifen's impact on cognitive function and presents a promising direction for breast cancer risk reduction.
Researchers at UPCI found that several plant extracts interact with estrogen receptors and induce strong estrogenic responses in female rats. The study highlights the need for caution when using these remedies, especially for women with a family or personal history of breast and uterine cancer.
A new study by Eckehard Liske, PhD, confirms the safety and efficacy of RemiFemin in relieving menopausal symptoms. The research shows that standardized herbal supplement works without affecting hormone levels, reducing hot flashes, mood swings, night sweats, and sleeplessness.
Researchers found that estrogen production protects females from cardiac hypertrophy, but not males. By blocking estrogen receptors, female mice developed cardiac enlargement similar to males.
A study found that hormone therapy slows atherosclerosis progression in monkeys with healthy blood vessels. Estrogen was most effective when given at an early stage, suggesting it may be less beneficial for women with advanced arterial disease.
A Mayo Clinic study finds an association between estrogen status and reduced coronary calcium and plaque area, suggesting a potential benefit against heart disease. Estrogen may modulate the calcium content of atherosclerotic plaques, slowing progression of atherosclerosis in women.
A study on female monkeys found that stress can reduce estrogen levels, leading to the development of atherosclerosis and increasing heart disease risk. The research highlights the importance of pre-menopausal behavioral and hormonal conditions for post-menopausal health.
A Stanford study shows that hormone therapy can improve mental health and reduce depression in women experiencing hot flashes, but may have negative effects on those without symptoms. The research suggests that women should discuss their individual risks and benefits with their doctor before making a decision.
Researchers at Lehigh University have discovered a possible cause-and-effect relationship between DHEA and the workings of the body's central nervous system. The study found that DHEA influences gene function through interaction with androgen receptors, potentially contributing to improved neuron survival and cognitive function.
A new study finds that raloxifene, an osteoporosis medication, reduces breast cancer risk by 76% in postmenopausal women with high estrogen levels. Women with low estrogen levels receive no reduction in risk.
A new study analyzing oral contraceptive use among women with epithelial ovarian cancer found a significant association between progestin levels and reduced risk. Women using low-progestin/high-estrogen contraceptives were more likely to develop ovarian cancer compared to those using high-progestin/high-estrogen contraceptives.
A study of 73 postmenopausal women found no significant changes in serum estrogen, cortisol, or follicle stimulating hormone levels after consuming soy protein for up to 6 months. Circulating thyroid hormone levels were modestly increased in those taking the highest dose of soy isoflavones.
A recent study at Duke University Medical Center found that letrozole, a new breast cancer treatment, was more effective than tamoxifen in shrinking tumors and reducing cell division. Patients taking letrozole showed significant tumor shrinkage and underwent fewer mastectomies compared to those on tamoxifen.
Two studies examine the link between sex hormones and coronary artery spasm, finding that estrogen levels during menstruation affect blood vessel function. Automated external defibrillators are also shown to be safe and easy to use by trained laypersons, paving the way for potential home sales.
A randomized controlled trial found that unopposed estrogen therapy reduced atherosclerosis progression by .0017 millimeters per year in postmenopausal women. The study also showed that cholesterol-lowering drugs had a similar effect when combined with estrogen, suggesting potential benefits for cardiovascular health in women at risk.
Researchers at Columbia University Irving Medical Center discovered that estrogen therapy improves consistency in older women, a key indicator of cognitive function. The study, which involved postmenopausal women taking hormone replacement therapy, found that estrogen users performed more consistently than those not taking the hormone.
A University of Michigan study found that female rats exposed to estrogen and cocaine showed increased sensitization, leading to faster craving and lower doses. The effects persisted even after the hormone was removed.
Researchers at the University of Illinois discovered that estrogen regulates fluid reabsorption in the male reproductive tract by triggering a protein involved in sodium transport. This finding suggests that blocking estrogen receptors could provide a new target for developing effective contraceptives for men.
Low levels of estrogen hormones in water may be responsible for the feminization of wild fish, according to a recent study. Researchers found that very low concentrations of estrogenic compounds released from sewage treatment plants were causing intersex and altered sex ratios in aquarium fish.
The study, published in the New England Journal of Medicine, found that estrogen replacement therapy for secondary stroke prevention was not beneficial. The Yale team also discovered a borderline higher risk of fatal stroke among women taking estradiol.
A new randomized, controlled clinical trial found no significant difference in the incidence of stroke or death among postmenopausal women who received estrogen therapy. The study suggests that estrogen should not be prescribed for preventing a second stroke or death in these patients.
Research suggests that estrogen replacement drugs can modify vein function in ways that increase the risk of venous thrombosis. Studies using adult female pigs found that hormone replacement therapies containing estradiol and SERMs altered cellular processes in veins, leading to changes in diameter, relaxation, and coagulation.
Estrogen controls lymphocyte formation and replenishment of the immune system by binding to hormone receptors found only in rare "precursors" within adult bone marrow. This discovery reveals that various kinds of stem cells may differ between fetal and adult life, protecting the fetus's immune system from estrogen-related compounds.
Researchers at the Mayo Clinic found a possible link between estrogen and reduced risk of Parkinson's disease. The study reviewed medical records of female patients with Parkinson's disease to examine the association with menopause type, age, and postmenopausal hormone therapy.
A study found that consuming five or ten grams of ground flaxseed daily for seven weeks reduced blood levels of certain estrogens associated with an increased risk of breast cancer. The researchers believe that lignans in flaxseed may lower estrogen levels by inhibiting enzymes involved in estrogen synthesis.
A new study found that estrogen patches can improve attention and memory skills in women with Alzheimer's disease. The research used estradiol, a type of estrogen shown to have an effect on the brain, and found significant improvements in attention and memory tests.
Researchers found that Raloxifene stimulated the growth of ovarian cancer cell lines, raising concerns about its use in ER+ patients. The study advises caution when prescribing Raloxifene to women with a history of breast cancer and ovarian cancer.
New data from the Nurses' Health Study suggests hormone replacement therapy reduces heart attack risk by 40% in postmenopausal women. However, taking higher doses of estrogen or combination therapy with progestin may increase stroke risk by 30%.
A recent study published by the Mayo Clinic has found that estrogen plays a crucial role in preventing bone resorption in elderly men. The research suggests that estrogen is essential for maintaining optimal bone metabolism in aging men, and highlights the importance of osteoporosis prevention for this demographic.
A low dose of estrogen was as effective as a higher dose in reducing bone turnover and preventing osteoporosis in older women. The study found that women taking 0.25 mg estradiol had no more side effects than those taking a placebo, improving bone health with fewer risks.
A study conducted at Massachusetts General Hospital found that over 90% of young women with anorexia nervosa suffered from significant bone loss. The research highlights the importance of regaining and maintaining a healthy weight in preventing or reducing bone loss.
The Mayo Clinic report concludes that the available data are insufficient to draw definitive conclusions about the use of soy isoflavones as an alternative to estrogen for hormone replacement in postmenopausal women. Randomized, placebo-controlled clinical trials are necessary to address the potential benefits and risks of isoflavone use.
A new study found that premenopausal women are more vulnerable to sudden, serious heart disease during their menstrual cycle when estrogen levels are at their lowest. The research also identified other health risks that worsen the odds for heart disease in young women.
Researchers found that male mice genetically altered to lack estrogen receptors became obese, with up to 170% increase in fat storage. Estrogen was also linked to improved fat burning ability in both males and females, challenging previous understanding of its role in female physiology.
A prospective study of 10,786 Italian women found a 40% lower risk of breast cancer in premenopausal women with the C-2 estrogen metabolism pathway, which produces less active by-products. Lifestyle changes such as physical activity and a low-fat diet high in cruciferous vegetables may shift estrogen metabolism from high-risk to low-risk.
Dr. Sherwin's research suggests that estrogen replacement therapy prevents some of the decline in verbal memory and ability to learn new material in postmenopausal women. This effect has been observed even in women who underwent surgical removal of their ovaries, which led to a sudden drop in estrogen levels.
Reduced estrogen levels caused by stress can lead to atherosclerosis and increased heart disease risk in women. Stress affects estrogen production, causing fatty deposits in arteries and potentially leading to heart attacks and strokes.
A preliminary study suggests that estrogen can effectively boost mood in women experiencing depression during perimenopause. The hormone significantly improved symptoms such as early morning awakening and loss of enjoyment, with relief achieved within three weeks.
A recent study found that older women with high natural estrogen levels are less likely to suffer cognitive decline. The researchers measured free estrogen and loosely bound forms of the hormone, finding a 70% lower risk of cognitive decline in those with the highest levels.