Articles tagged with Endocrine Disruptors
A study of over 3,000 mother-child pairs from six European countries found an association between prenatal bisphenol A exposure and increased risk of asthma and wheezing in school-age girls. The study revealed a high prevalence of BPA in maternal urine during pregnancy.
A recent study found that prenatal exposure to phthalates in maternal and cord blood may affect birth outcomes in infants, with potential estrogenic effects in females and anti-androgenic effects in males. Higher levels of phthalates were also associated with smaller head circumference in all infants.
A recent study found that exposure to complex mixtures of endocrine disrupting chemicals during pregnancy can impact children's brain development and language acquisition. The research, conducted in collaboration with multiple institutions, used a novel approach linking human population studies with experimental cell and animal models.
Researchers developed a new live cell quantitative analysis of ER dynamics using fluorescence recovery after photobleaching (FRAP) to study the effects of endocrine disrupting chemicals on gene expression. The method enables faster and more accurate testing of larger numbers of compounds, revealing complex dynamics between receptor mob...
A systematic review presents evidence that environmental obesogens, such as hormone-disrupting chemicals, play a significant role in childhood and adult obesity. Dr. Leonardo Trasande recommends simple policies to reduce exposure and suggests economic benefits of limiting public exposure.
A recent study found that women with higher levels of PFAS in their system are 20% more likely to stop breastfeeding early. This is significant because almost every human on the planet is exposed to these endocrine-disrupting chemicals, which can have detrimental effects on reproductive health.
Researchers found that men exposed to endocrine disruptors in utero are twice as likely to have low semen volume and sperm count. Exposure to pesticides, phthalates, and heavy metals is associated with poorer sperm quality.
Researchers found that exposure to brominated flame retardants can cause premature development of the mammary glands, increasing the risk of breast cancer. The study, led by Professor Isabelle Plante, suggests that young women exposed to BFRs in utero and through breastfeeding are now at higher risk for breast cancer.
A new study by Silent Spring Institute found that consumers who avoid products containing endocrine disruptors, such as parabens and BPA, have significantly lower levels of these chemicals in their bodies. The study showed that reading ingredient labels and avoiding certain products can reduce exposures to these harmful chemicals.
Researchers studied leech reproduction and found that EE2 had little impact on abundance but some effects on gonad size. Leeches may be less sensitive to endocrine disrupting compounds than previously thought.
A set of reviews concludes that hundreds of studies link widespread health issues including infertility, diabetes, and impaired brain development to hormone disruptors in pesticides, flame retardants, and certain plastics.
Researchers at Oregon State University found that low levels of endocrine-disrupting chemicals in waterways can alter the DNA structure of fish, passed on through three generations. The study used inland silversides and measured methylation patterns, revealing consistent changes across generations.
A new Duke University study finds that microplastic fibers cause cellular changes in fish, including damage to gills and increased egg production in female fish. The study suggests that chemicals from the fibers may be acting as endocrine disruptors, threatening both freshwater and marine organisms.
Researchers will investigate the association between endocrine disruptors and endometriosis severity. The study aims to answer two key questions: whether levels of these chemicals inside the uterus are linked to endometriosis and if they affect the severity of the disorder.
Researchers at UNIGE identified genetic causes of susceptibility to phthalates, a common endocrine disruptor, which affects fertility and sperm quality. The study revealed that epigenetic changes caused by phthalate exposure can be passed down to future generations.
A new study found that endocrine disruptors can alter female reproduction and sexual development in offspring, affecting reproductive health throughout multiple generations. The researchers observed delayed puberty, abnormal cycles, and ovulation in third- and fourth-generation females.
Researchers report that tadpoles and adult female frogs exposed to endocrine disruptors develop metabolic disorders. Exposure leads to delayed metamorphosis, lower reproductive success, and smaller offspring.
The EPA has shifted focus to high-throughput computational models to quickly identify chemicals that require more scrutiny, following a slow start in its previous approach. Researchers have made significant progress, including the development of estrogen and androgen receptor models.
The Endocrine Disruptor Screening Program uses a tiered testing strategy to assess the potential of pesticides and environmental contaminants on hormone systems. The finalized test method is a result of collaborative efforts between EPA scientists and Japanese colleagues.
A European Commission proposal to define and identify endocrine-disrupting chemicals has been widely criticized by experts, who argue it sets an unrealistic burden of proof and limits regulatory action. The Endocrine Society, led by UMass Amherst biologist Thomas Zoeller, claims the proposal will create gaps in identification criteria,...
Dr Lisa Connolly is leading a €4m international initiative to investigate the effects of natural toxins and manmade chemicals on human hormones, causing illnesses like cancer, obesity and infertility. The PROTECTED project aims to develop innovative analysis tools to protect public health from these endocrine disruptors.
This study proposes zebrafish as a model to predict EDCs effects on humans. Key genes vitellogenin and aromatase cytochrome P450 were monitored in zebrafish to detect EDC presence, offering new mechanisms for reproductive status alteration.
Laura Vandenberg, a UMass Amherst environmental health scientist, has won the 2016 Pearl Award for her work on endocrine disrupting chemicals. Her research reveals associations between low-level chemical exposures and disease, highlighting the need for rethinking safe exposure limits.
The scientific community has established criteria for identifying endocrine disruptors, which will inform regulatory decisions on substances affecting human health. The principles focus on substance effects on the endocrine system and adverse health outcomes.
A group of 7 researchers from Europe and the US show that consensus exists around EDC definition and propose a logic-based approach similar to carcinogen identification. This guidance aims to resolve the 3-year blockage in publishing scientific criteria, allowing for efficient protection of public health.
A group of European and US researchers has provided a clear framework for identifying endocrine-disrupting substances (EDCs) and regulating them. The report, published in Environmental Health Perspectives, defines EDCs as substances altering the hormonal system and causing adverse health effects.
Research reveals that low concentrations of 5α-dihydrotestosterone can induce complete or incomplete sex reversal in female Pelophylax nigromaculatus frogs. Environmental androgenic endocrine disrupting chemicals pose a threat to aquatic ecosystems, highlighting the need for increased regulation.
Research finds that BPA exposure reduces maternal and paternal care in mice, with females adjusting their behavior based on male partner's exposure. The study suggests potential human implications for social, emotional, and cognitive development.
Researchers at Goethe University found that two out of ten plastic rings in baby teethers release chemicals with hormone-like effects. These additives can inhibit the effects of androgens such as testosterone and act like natural oestrogen in the body. The study highlights the need for manufacturers, regulatory agencies, and scientists...
A study found that 2 out of 10 plastic teethers contained significant endocrine activity, including methylparaben and unidentified compounds. The presence of parabens in one product is unusual, highlighting the need for manufacturers and regulators to address chemical exposure in baby products.
Research finds that growth-promoting hormones like TBA used in beef production can persist in the environment at higher concentrations and for longer durations than previously thought. This persistence has significant impacts on aquatic ecosystems, including disrupting reproductive cycles and altering entire food webs.
A new study presents evidence that brief exposure to endocrine-disrupting chemicals in infancy can lead to fatty liver disease in adulthood. The researchers found that bisphenol A (BPA) and tributyltin caused liver damage consistent with human nonalcoholic hepatic steatosis, and altered gene expression patterns that may drive obesity.
A new study reveals that prenatal exposure to low doses of polychlorinated biphenyls (PCBs) can alter the developing brain in an area involved in metabolism. The effects are apparent even two generations later, with increased body weight observed only in descendants of females exposed to PCBs during pregnancy.
A German-Danish team of researchers found that endocrine-disrupting chemicals interfere with human sperm function, changing swimming behavior and triggering digestive enzyme release. The study suggests these chemicals may contribute to widespread fertility problems in the Western world.
A recent study by Vandenberg et al. found that bisphenol A (BPA) has significant effects on humans at incredibly low doses, often ten to forty times lower than previous toxicology studies. This new understanding of BPA's impact on human health and wildlife highlights the need for stricter regulations.
Researchers developed TAML activators to remove hazardous endocrine disruptors from water, testing their safety on zebrafish embryos. The study found that the molecules were non-toxic at typical concentrations but three out of seven showed impairment at higher doses.
A new five-tiered testing system, called the Tiered Protocol for Endocrine Disruption (TiPED), can help manufacturers avoid creating products with harmful endocrine disrupting chemicals. The researchers hope that chemists and companies will incorporate these tests at the early stages of product development to create safer products.
Researchers from NC State University have developed a safety testing system called TiPED to help chemists design inherently safer chemicals. The system aims to identify potential endocrine disruptors before they are used in commercial products, benefiting consumers and reducing exposure to harmful chemicals.
Children with higher phthalate levels have nearly five times the odds of being obese compared to those with lower levels, according to a new study. The research found that elevated DEHP levels correlated with body mass index and percentage of fat mass, increasing obesity risk independently of physical activity and daily calorie intake.
Research found a seven-fold increased risk of undescended testicles in sons born to women taking multiple painkillers during pregnancy. The study suggests that exposure to certain chemicals, including mild analgesics, can disrupt testosterone production and lead to poor semen quality and testicular cancer.
A new study has revealed that both low-income and affluent communities in California have high levels of endocrine disruptors in their homes, with indoor air pollution posing a significant health risk. The study, which analyzed indoor and outdoor air samples from 40 low-income and 10 affluent homes, found that levels of these substance...
Scientists tested eight common oil spill dispersants and found none showed significant hormone disruption activity. Only high concentrations exceeded safe levels of cell death, but other potential toxins remain untested.
A study by UC Davis researchers found that triclocarban, a common antibacterial chemical, alters hormonal activity in rats and human cells. In male rats, testosterone-dependent organs grew abnormally large after exposure to the chemical.
Dartmouth researchers discover that low doses of arsenic disrupt steroid hormone receptor signaling, affecting biological processes and disease risks. The study found that arsenic suppresses the ability of critical receptors to respond to normal hormone signals.
A new study finds that oxygen deficiency can impair fish reproduction by disrupting endocrine function and reducing fertility rates. Long-term exposure to hypoxia can lead to major declines in fish populations, potentially causing extinction for some species.