Researchers at Polytechnique Montréal developed an open-space microfluidics technology that eliminates channels, reducing stress on cells and increasing compatibility with cell-culture standards. The system uses microfluidic multipoles to create patterns that can be used for disease detection and diagnosis.
A new tool, TBI-CareQOL Measurement System, standardizes the measurement of physical, mental and emotional effects experienced by caregivers of people with TBI. The researchers' findings could inform clinical care, caregiver training and support programs, and even caregiver reimbursement policies.
A new study by Penn State researchers finds that male fence lizards' physical traits and behaviors used to attract mates remain unchanged under low levels of stress. This suggests that these traits are more resilient to stress than previously thought.
Researchers at Beth Israel Deaconess Medical Center discover relationship between leucine and tamoxifen resistance in ER+ breast cancer. A diet high in leucine may fuel the growth of breast cancer cells, while reducing leucine levels could be beneficial for patients with ER+ breast cancer.
Treatment at Canada's only early intervention program for youth with mood and anxiety disorders leads to improved symptoms, functioning, and access to psychiatric care in the most appropriate settings. Patients who disengage from treatment have less severe symptoms than those who stay engaged.
Afro-Italian women entrepreneurs are transforming notions of beauty and Italian identity with their black fashion, style, and hair-care products. They are leveraging the internet to market their products, build community, and challenge racist narratives, potentially awakening Italy's moribund economy.
A pilot study found that transcranial magnetic stimulation temporarily increases activity in the brain's hippocampal-cortical network, leading to improved memory recall. The treatment showed temporary improvements in memory function compared to a placebo, with participants recalling memories 31% better after stimulation.
Researchers at Monash University have identified two new epigenetic regulators, TAF5L and TAF6L, that maintain the self-renewal of embryonic stem cells by activating the oncogene c-Myc. These findings have significant potential for regenerative biology and cancer research.
Researchers at the University of Sydney developed a method to predict salmonella outbreaks and found that future epidemics are likely to be more severe. The study suggests that genetic networks of salmonella pathogens are linked through just a few degrees of separation, indicating an increasing severity of future epidemics.
Researchers studied L-carnitine's thermodynamic properties to optimize its transformation into a pharmaceutical agent. The study aimed to improve the production methods and dosage forms of this substance, which is popular among athletes due to its energy metabolism correcting effects.
Researchers from Finland and Brazil developed a method that uses both plant and soil data to produce a map of soil properties in Amazonia. The study leverages digital herbarium databases and fern species occurrence data to estimate soil properties, providing valuable insights for conservation efforts.
Researchers are testing the RTS,S/AS01 vaccine, which provided partial protection against malaria in young children, in a pilot study in three countries. The goal is to vaccinate approximately 120,000 children annually and monitor its impact on preventing mortality from malaria.
A new study reports that cervical adenocarcinoma incidence rates are increasing in non-Hispanic whites, particularly among women aged 40-49 and 50-59. This trend underscores the need for intensified efforts to improve screening utilization and HPV vaccination.
Scientists develop DNA nanodevice that uses near-infrared light to guide stem cells to wounds, promoting muscle tissue regrowth in mice. The system successfully activated receptors, causing cells to move and grow, with treated mice showing increased signs of regeneration.
Research by Lancaster University reveals that school bullying increases the risk of mental health problems and unemployment by 40% and 35%, respectively, at age 25. Bullying also reduces income and academic achievement, particularly among those who experience persistent or violent forms of bullying.
A new learning system developed by MIT researchers improves robots' abilities to shape materials and predict their interactions. The system, called a learning-based particle simulator, can handle diverse materials, including rigid objects, liquids, and deformable materials.
Researchers found evidence of a solid inner core in Mercury, approximately 1,260 miles wide and making up half the planet's core. This discovery helps scientists better understand Mercury's interior and offers clues about how rocky planets change over time.
Researchers found that using psychological techniques to communicate periodontal disease risk improved dental hygiene and reduced gum inflammation over a three month period. The study also associated the intervention with improved frequency of interdental cleaning.
A Canadian study of over 2,400 families found that spending two hours or more of screen time per day is associated with clinically significant behavioral problems in preschoolers. Organized sports and good quality sleep were also identified as protective factors against the negative effects of screen time.
A new species of Mongolian dinosaur, Gobihadros, has been discovered with complete skeletal remains. The discovery sheds light on the evolution of hadrosaurs during the Late Cretaceous Period.
Researchers have detected new per- and polyfluoroalkyl substances (PFASs) in the Cape Fear River, including some previously unknown compounds. Levels of these contaminants are decreasing due to changes in wastewater disposal practices.
Researchers discovered a potentially devastating foot disease in Chile's endangered huemul deer population, with severe pain and death caused by the condition. The study's findings highlight the need for improved monitoring and collaboration to help protect the critically endangered species.
Researchers at Georgia State University discovered that societal expectations around gender roles can alter the human brain at a cellular level. This finding suggests that epigenetic marks in the brain drive differences between males and females, influenced by gender identity rather than just biological sex.
Researchers developed a drug resistance index to track global trends in antibiotic therapy effectiveness. The study found that high-income countries generally have lower rates of resistance, while low- and middle-income countries face greater challenges due to limited access to newer drugs.
A new study found that transfer RNA-derived fragments play a significant role in gene expression, differing by cancer type and sex of the patient. The mitochondrion is involved in these interactions, particularly with repetitive elements.
New research finds elevated levels of fatty acid transporter protein 2 (FATP2) in immune-suppressing cells, which can slow tumor growth and aid cancer treatments. The study also discovered an energy-granting lipid that FATP2 produces and traffics into cells, leading to its potential as a therapeutic target.
Scientists at the University of Hawaii have developed a technique to measure living coral on reefs by analyzing DNA in small seawater samples. This new method, known as metabarcoding, can track changes in coral reef health and detect rare species.
A Harvard University study explores the genetics behind the evolution of flightless birds, finding that different species turn to similar regulatory pathways when evolving flight loss. The team discovered a shared suite of morphological changes that led to a similar body plan across all flightless bird species.
The team tested two devices, one that can change conformation in the esophagus to exit after drug delivery and another that can reside in the stomach until intentionally triggered. The devices were inspired by design principles of transformable materials and showed promise for fast and robust response.
Climate change could cause Western Hemisphere cloud forests to shrink and dry by 60-80% in as few as 25 years. The loss of clouds would nearly disappear the highly diverse alpine ecosystems above these equatorial cloud forests, known as páramo.
A Monash University study found that exposure to coffee-related cues can trigger cognitive benefits, such as increased alertness and energy levels, in participants from Western cultures. The research used mental construal theory and demonstrated the power of psychological associations in shaping our thinking and behavior.
Researchers at Yale University successfully restored circulation and cellular activity in a pig's brain four hours after its death using a specially designed chemical solution. However, the treated brain lacked recognizable global electrical signals associated with normal brain function.
Researchers have discovered that tsunami-like solitary waves, known as clusters, move in synchrony with each other. The findings were made possible by observing how the waves behave when they occur in a series, revealing intriguing patterns of movement and coordination.
The US Army has awarded up to $50 million over five years to eight academic teams pursuing basic research across various scientific disciplines. The teams will study topics including heat energy transfer, plant and pollen distribution, and the restorative effects of sleep.
A new Yale study uncovers key relationship between storm events, ecology, and topography in moderating greenhouse gas release from rivers and streams. Concentrations of three greenhouse gases increase during rainstorms in wetland streams but decrease or remain constant in forested streams.
Dr. Nicole Brandt will receive the 2019 Dennis W. Jahnigen Award for her dedication to training health professionals in care for older adults. She has developed a geriatrics and palliative care pathway, an accredited geriatrics residency, and secured funding for innovative programs supporting older adults.
A novel plasma water treatment method by electrical discharge has been developed, producing drinking water as suitable for consumption as ozonation, without carcinogens or high costs.
A CABI-led study found that women face unequal access to agricultural advisory services, hindering their contribution to farming. The research proposes training female extension workers as 'lead contact' farmers to improve information dissemination and reduce gender inequalities.
A new AI system called FocalNet has been developed to aid radiologists in detecting prostate cancer, achieving 80.5% accuracy in reading MRI scans. The system uses machine learning to evaluate tumors and predict their aggressiveness, providing diagnostic guidance to less-experienced radiologists.
Regular ultrasounds at 36 weeks' gestation can identify undiagnosed breech presentations, reducing the risk of complications for both mothers and babies. By performing these scans, hospitals could potentially save thousands of pounds annually while improving patient outcomes.
The US Preventive Services Task Force now finds no evidence to support or refute screening for elevated blood lead levels in asymptomatic children under 5 years old and asymptomatic pregnant women. This recommendation updates the 2006 statement and is based on a review of existing literature.
The 2017 pneumonic plague outbreak in Madagascar was characterized by a dominance of the pneumonic form, which accounted for 78% of reported clinical cases. The number of confirmed cases doubled every five days after the initial stage of the outbreak.
Researchers have discovered a potential new treatment for renal fibrosis by selectively activating AT1 receptors on T cells, which may help limit scar formation in the kidney. The study found that activating these receptors mitigates renal fibrogenesis by inhibiting Th1 differentiation and renal accumulation of pro-fibrotic macrophages.
A new study in Heliyon identifies distinct opinion patterns on positional issues among Canadian voters, suggesting a micro-targeting marketing strategy could be effective. The research found that many Canadians have strong opinions on divisive issues, comparable to conventional vote predictors like party identification.
A new study finds that climate change will lead to the extinction of both seaside and saltmarsh sparrow species, with saltmarsh sparrows facing local extinction in as little as 30 years. Rising sea levels will reduce available habitat and increase flooding rates, making it difficult for these birds to thrive.
A new study found that having Black female role models in STEM is crucial for black women college students to feel a sense of belonging. The research, led by Indiana University-Purdue University Indianapolis School of Science, also discovered that seeing a Black male scientist can signal more belonging, while high stigma consciousness ...
Joanne Kurtzberg, MD, has been awarded the 2019 Bernard Sanberg Memorial Award for her groundbreaking work in pediatric hematology and regenerative medicine. The award recognizes her clinical trials that have led to positive results in treating adult ischemic stroke patients with cord blood therapy.
A new approach, PRO-cision Medicine, uses patient-reported outcomes to personalize cancer care. This method provides valuable information on patients' symptoms and functioning, guiding clinicians in making informed decisions.
Researchers found that high testosterone and cortisol levels are associated with increased aggression in boys, while girls with high empathy levels exhibit lower aggression. The study suggests a complex interplay between hormones and empathy in shaping aggressive behavior in children.
Research reveals that white sharks immediately vacate their preferred hunting grounds when orcas arrive, resulting in no shark sightings for up to a year. Elephant seal colonies also indirectly benefit from these interactions, with significantly reduced predation events during the orca presence period.
Researchers have identified a pattern of brain activity reflecting anger experienced during dreaming. The study found that frontal alpha asymmetry is related to anger in both wakefulness and dreams.
A study found that metformin reduces left ventricular hypertrophy (LVH) in prediabetic and pre-existing heart disease patients, leading to lower cardiovascular risks. The MET-REMODEL Trial showed significant benefits of metformin on LVH, blood pressure, oxidative stress, and body weight.
Researchers identified 11 primary challenges faced by therapists, including unrealistic agency expectations, inadequate support, and heightened case complexity. Therapists reported needing targeted trainings to improve service delivery for children and families.
DNDi and Atomwise collaborate to develop first-in-class treatments for Chagas disease using AI, delivering drug-like compounds that will undergo further optimization and potential drug development. The research aims to address a public health challenge affecting millions worldwide.
A study published in Biological Conservation highlights the importance of tree dens for pandas raising infants in native habitats. Tree dens provide a more stable microclimate than cave dens, facilitating offspring survival. This research emphasizes the need to preserve large old trees for giant panda conservation.
Researchers discovered multiple potential targets for glioblastoma by systematically profiling patient-derived brain tumour cells. They found that adult glioblastoma cells rely on genes important for brain development in infancy, highlighting the need for new research to understand the developing human brain.
Researchers found that the nutrient composition of interstitial fluid surrounding pancreatic tumors differs from blood and culture medium used to grow cancer cells. This discrepancy suggests growing cancer cells in a more similar environment could help predict how experimental drugs will affect cancer cells.
A new study from Iowa State University found that same-sex couples are less likely to be approved for mortgages, with approval rates ranging from 3-8% lower. Same-sex applicants also faced higher interest and fees, with the difference adding up to $86 million annually.
The PCV10 pneumococcal vaccine significantly reduced the incidence of serious pneumococcal disease among children under five years old, with a 92% decline in cases involving the ten targeted strains. The vaccine also provided herd immunity benefits by reducing disease transmission among older, unvaccinated age groups.
A study published in PLOS Biology found that oxytocin administration can block excess drinking in alcohol-dependent rats, suggesting a potential novel pharmaceutical intervention for treating alcohol-use disorder. Oxytocin also blocked altered GABA signaling in the brain region affected by alcohol dependence.