Add BrightSurf on Google Email

Science News Archive 2022 - Page 30


Page 30 of 448

Scientists develop 12-hour method to predict diabetes onset in patients using artificial intelligence

Researchers at Klick Applied Sciences have created a machine learning model to predict diabetes onset in patients using just 12 hours of data from continuous glucose monitors. The study showed high accuracy in identifying prediabetes, healthy patients, and those with Type 2 diabetes, offering a potential tool for early disease prevention.

SourceKlick Applied Sciences·TypeComputational simulation/modeling·DateDec 2, 2022

Brain aging is not one-size-fits-all: Chronological age, biological age and gender affect the shrinkage of different brain areas

Research reveals that brain function networks are affected differently by aging, gender, and blood immune factors. The study found correlations between cytokine clock, brain shrinkage, and gender, with females having a faster ticking cytokine clock.

SourceBuck Institute for Research on Aging·JournalProceedings of the National Academy of Sciences·TypeData/statistical analysis·DateDec 2, 2022

Commercial dishwashers destroy protective layer in gut

A new study by researchers at the Swiss Institute of Allergy and Asthma Research found that commercial dishwashers' rinse agents can damage the gut's epithelial barrier, leading to chronic diseases. The study used human intestinal organoids and analyzed the effect of detergents and rinse aids on gut cells.

SourceUniversity of Zurich·JournalJournal of Allergy and Clinical Immunology·TypeRandomized controlled/clinical trial·DateDec 1, 2022

Automated chemical reaction prediction: Now in stereo

Researchers demonstrate the expanded use of a computational method called AFIR, predicting pericyclic reactions with accurate stereoselectivity based on target product molecule information. The technique successfully handles molecules up to 52 atoms and predicts stereochemistry for reactions that break Woodward-Hoffman rules.

SourceHokkaido University·JournalJournal of the American Chemical Society·TypeExperimental study·DateDec 1, 2022

A self-powered ingestible sensor opens new avenues for gut research

UC San Diego researchers have developed a self-powered ingestible biosensing system that provides continuous monitoring of gut metabolites, unlocking new understanding of intestinal health and its impact on human health. The battery-free sensor is powered by glucose and can measure glucose levels in the small intestine for up to 14 hours.

SourceUniversity of California - San Diego·JournalNature Communications·TypeExperimental study·DateDec 1, 2022

Step closer to tackling drug resistant parasites in Brazil

Scientists at the University of York have identified an enzyme that makes Leishmania infantum parasite resistant to miltefosine, a medication used to treat visceral leishmaniasis in Brazil. The discovery opens up potential for developing a blood test to predict patient outcome and tailor treatment to individual patients.

SourceUniversity of York·JournalEBioMedicine·DateDec 1, 2022

Study conducted at hospital in São Paulo state detects measles antibodies in only 75% of under-fifteens

A study conducted in Brazil reveals that only 75.8% of under-fifteen children in São Paulo have antibodies against measles, falling short of the ideal 94% target to prevent outbreaks. The finding is a warning sign that Brazilian children are not achieving herd immunity, making them susceptible to infection.

Children with type 1 diabetes miss more school, study suggests

A Cardiff University-led study found that children with type 1 diabetes who struggle to manage their blood glucose levels are absent for 15 more sessions per year, compared to 7 for those with the healthiest levels. These absences result in lower educational attainment, including five grades lower in GCSEs.

SourceCardiff University·JournalDiabetes Care·TypeData/statistical analysis·DateDec 1, 2022

Adoption of front-of-pack nutrition warnings can help decrease obesity, cardiovascular disease, type-2 diabetes and some cancers in the Americas

A recent study led by the University of Nevada, Reno and the Pan American Health Organization suggests that the adoption of front-of-pack nutrition labeling can help reduce poor-nutrition related non-communicable diseases in the region. Improved FOPNL systems have been associated with improved diet quality and reduced risk of NCDs.

SourceUniversity of Nevada, Reno·JournalThe Lancet Regional Health - Americas·DateDec 1, 2022

Integrated platform promises to accelerate drug discovery process

Researchers developed an integrated approach to accelerate drug discovery by combining complex datasets from two screening platforms and next-generation metabolomics analysis. The new framework identified known compounds, confirmed mechanisms of action, and discovered novel compounds with unique biological signatures.

SourceUniversity of California - Santa Cruz·JournalProceedings of the National Academy of Sciences·DateDec 1, 2022

UNAIDS Executive Director Winnie Byanyima and Deputy Executive Director Matthew Kavanagh highlight inequalities in sex and gender, access to drugs and access to funding, as barriers to tackling AIDS and other pandemics

Inequalities in sex and gender, access to antiretroviral drugs, and inadequate funding hinder global efforts to combat AIDS and other pandemics. UNAIDS Executive Director Winnie Byanyima and Deputy Director Matthew Kavanagh emphasize these disparities as critical obstacles to effective pandemic response

SourcePLOS·JournalPLOS Global Public Health·DateDec 1, 2022

Long COVID patients and those with other illnesses experience similar, negative lingering effects during the pandemic

Research suggests that long COVID patients share similar lingering negative effects on physical, mental, and social well-being with individuals who have other illnesses. The study found moderate-to-severe residual symptoms in 40% of COVID-positive participants and 54% of those who tested negative.

SourceUniversity of California - Los Angeles Health Sciences·JournalJAMA Network Open·TypeRandomized controlled/clinical trial·DateDec 1, 2022

Growing evidence for the role of the immune system in Parkinson’s disease

The latest research evidence suggests that inflammation may play a causative role in Parkinson's disease. Multiple independent studies have provided evidence of the involvement of central and peripheral immune and inflammatory processes in PD, with increasing evidence suggesting an association with autoimmune conditions.

SourceIOS Press·JournalJournal of Parkinson’s Disease·TypeSystematic review·DateDec 1, 2022

Study in mice suggests that expression of estrogen-related gene can impact post-menopausal breast cancer risk and prevention strategies

A study using a mouse model found that over-expression of the Esr1 gene increased the risk of developing estrogen receptor-positive breast cancer in older women. Giving anti-hormonal drugs to mice with Esr1 over-expression lowered or reversed this risk.

SourceGeorgetown University Medical Center·JournalAmerican Journal Of Pathology·TypeExperimental study·DateDec 1, 2022

Where did Omicron come from?

Researchers found viruses with Omicron-specific mutations in COVID-19 patients in six African countries two months before the variant was detected. The study suggests that Omicron emerged gradually, evolving from existing human immunity, and spreading rapidly across Africa before global detection.

Making sense of coercivity in magnetic materials with machine learning

Researchers developed a new approach to analyze coercivity in soft magnetic materials using machine learning and data science. The method condenses relevant information from microscopic images into a two-dimensional feature space, visualizing the energy landscape of magnetization reversal. This study showcases how materials informatics...

SourceTokyo University of Science·JournalCommunications Physics·TypeExperimental study·DateDec 1, 2022

Researchers from Insilico Medicine, University of Copenhagen, and University of Chicago unravel molecular secrets hidden in premature aging diseases and cancer using AI

Scientists used AI-driven PandaOmics platform to analyze gene expression datasets from DNA repair diseases, identifying biomarkers associated with treatment response. The study focused on genes that stratify cancer patients by survival outcomes, providing potential targets for personalized therapies.

SourceInSilico Medicine·JournalCell Death and Disease·TypeData/statistical analysis·DateDec 1, 2022

Women with elevated breast cancer risk could see mortality benefit from estrogen-blocking drugs

A new study suggests that estrogen-blocking drugs can not only prevent breast cancer but also reduce the risk of dying from the disease. Researchers used computer models to determine the lifetime benefits and harms of these treatments for women at high risk, finding a significant impact on mortality.

SourceGeorgetown University Medical Center·JournalJournal of Clinical Oncology·TypeComputational simulation/modeling·DateDec 1, 2022

When FMD hits a family, abdominal aortic aneurysms may too

Researchers discover a shared genetic basis between fibromuscular dysplasia (FMD) and abdominal aortic aneurysms (AAA), with males more likely to develop AAA when a family member has FMD. The study suggests that screening for AAA in male relatives of patients with FMD may be beneficial, along with established guidelines.

SourceMichigan Medicine - University of Michigan·JournalCirculation Genomic and Precision Medicine·TypeData/statistical analysis·DateDec 1, 2022

News tips from UCLA Health: New hope for deadly brain cancer; Mating patterns vs genetics; Do housing interventions improve health? Air pollution and neurodegenerative disease

Researchers at UCLA Health have made significant breakthroughs in understanding deadly brain cancer and the role of housing interventions. A study found a cancer vaccine to be highly effective in treating glioblastoma multiforme, a nearly lethal brain cancer. Additionally, a survey highlighted the need for increased diversity in gastro...

SourceUniversity of California - Los Angeles Health Sciences·JournalJAMA Oncology·TypeExperimental study·DateDec 1, 2022

Dr. AI, what’s my diagnosis?

A team of researchers developed a neural network that can analyze digital biopsy images to diagnose breast cancer, identifying the presence of PD-L1 protein. The AI system outperformed human pathologists in 70% of cases, with high accuracy rates and potential for personalized medicine.

SourceTechnion-Israel Institute of Technology·JournalNature Communications·TypeImaging analysis·DateDec 1, 2022