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Science News Archive March 2022 - Page 22


Page 22 of 44

ENGOT and The GOG Foundation, Inc. (GOG) announce promising first results of new maintenance therapy for advanced or recurrent endometrial cancer

A Phase 3 clinical study of selinexor as maintenance therapy for advanced or recurrent endometrial cancer showed a 30% decrease in hazard for progression or death compared to the placebo-controlled group. Patients with functional p53 genes saw the most pronounced effect, with median progression-free survival at 10 months longer.

SourceThe GOG Foundation Inc·TypeRandomized controlled/clinical trial·DateMar 17, 2022

Data science to help find the most appropriate rehabilitation methods for osteoarthritis patients

A study using data science and mathematical models identifies the most suitable rehabilitation method for each patient with osteoarthritis. The research aims to provide personalized treatment recommendations for healthcare professionals, ultimately leading to more effective care for patients.

SourceUniversity of Jyväskylä - Jyväskylän yliopisto·JournalAnnals of Medicine·TypeRandomized controlled/clinical trial·DateMar 17, 2022

Pusan National University scientists discover why women are more resistant to nonalcoholic fatty liver disease than men

Researchers found that female mice produce more of the FPR2 protein, which helps prevent NAFLD, and that estrogen mediates its production. This discovery highlights the need for sex-balanced animal experiments and could lead to novel treatments and gender-based therapies for NASH

SourcePusan National University·JournalNature Communications·TypeExperimental study·DateMar 17, 2022

Researchers find a ‘vicious cycle’ between excessive daytime napping and Alzheimer’s dementia

A new study found that longer, more frequent daytime napping in older adults predicted worse cognitive performance and an increased future risk of Alzheimer's dementia. The researchers discovered a bi-directional link between the two, where excessive daytime napping sped up the increase in daytime napping during aging.

SourceBrigham and Women's Hospital·TypeData/statistical analysis·DateMar 17, 2022

New study finds aerosolized hydrogen peroxide can significantly reduce C. difficile infections in hospital settings

New data published in AJIC suggests aerosolized hydrogen peroxide can significantly reduce Clostridioides difficile (CDI) infections among patients in large, acute-care facilities. A study found a 41% decrease in HA-CDI rates after implementing an aerosolized hydrogen peroxide system.

SourceAssociation for Professionals in Infection Control·JournalAmerican Journal of Infection Control·TypeData/statistical analysis·DateMar 17, 2022

THE LANCET CHILD & ADOLESCENT HEALTH: One in three children with disabilities globally have experienced violence in their lifetimes

Children and adolescents with disabilities experience physical, sexual, and emotional violence at higher rates than those without disability. The study highlights the urgent need for collaborative efforts to raise awareness of all forms of violence against children with disabilities.

SourceThe Lancet·JournalThe Lancet Child & Adolescent Health·TypeSystematic review·DateMar 17, 2022

Researchers develop innovative approach to measure shallow water depth with satellite data

A machine learning algorithm uses data from two Earth observation satellites to determine the depth of optically shallow waters, improving navigation and coastal management. The study focused on tropical regions but aims to generate global high-resolution bathymetric maps for near-shore shallow regions.

SourceJournal of Remote Sensing·JournalJournal of Remote Sensing·TypeImaging analysis·DateMar 17, 2022

For youth with a heart defect, shift to adult-focused care is key to health, quality of life

Most people born with heart defects now survive past childhood, requiring seamless transition to adult-oriented healthcare. The American Heart Association updates guidelines for managing congenital heart disease in adolescents and young adults, highlighting the importance of involving individuals and families in research.

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateMar 17, 2022

A deeper insight into the bag of tricks of bacteria

Researchers led by Cynthia Sharma explore a vast universe of RNA-binding proteins in bacteria, which play crucial roles in stress response and virulence control. The team aims to advance understanding of these proteins, revealing fundamental biological principles that could lead to novel biotechnological methodologies or antimicrobial ...

Carbon molecular sieve integrated graphene sensor: New paradigm in atmospheric gas sensing and molecular identification

A new paradigm in atmospheric gas sensing has been achieved using a graphene sensor integrated with carbon molecular sieve functionality. The sensor demonstrates selective gas detection, including ammonia, at room temperature with a fast response time of seconds.

SourceJapan Advanced Institute of Science and Technology·JournalACS Applied Materials & Interfaces·DateMar 17, 2022

Genetic ancestry matters in childhood leukemia treatment success

Researchers found that genetic ancestry is associated with differences in biology of acute lymphoblastic leukemia (ALL) and is an independent factor contributing to treatment outcomes. Children from East Asian and South Asian backgrounds had better survival rates than Caucasian children, with Indian children having the best outcomes.

SourceNational University of Singapore, Yong Loo Lin School of Medicine·JournalJAMA Oncology·TypeData/statistical analysis·DateMar 17, 2022

The roots of #BlackLivesMatter

A new research group aims to bridge historiographical gaps in the understanding of the Black Power movement's influence on America's democracy and values. The project will examine lesser-known groups and topics to illustrate the struggle between competing ideals of US democracy.

When and how mutant clones expand in normal endometrium

A recent study found that mutant clones expand in the normal endometrium through a rhizome structure, which arises from a common ancestral clone. This expansion increases the risk of developing endometriosis and endometrial cancer. The study proposes a new model of clonal expansion in the normal endometrium.

SourceNiigata University·JournalNature Communications·DateMar 17, 2022

Global instability and the timing of Russia’s attack on Ukraine

Research by David Carter and Scott F. Abramson suggests territorial conflicts tend to emerge when great powers are embroiled in crisis, creating opportunities for revisionist states like Russia to make aggressive moves. The study found over 60% of European territorial claims were made during the most unstable years after 1815.

SourceWashington University in St. Louis·JournalInternational Organization·TypeMeta-analysis·DateMar 17, 2022

World’s vulnerable are being polluted in their own homes as they cook, finds new Surrey study

A new study from the University of Surrey found that three-quarters of kitchens in low-income homes across 12 major global cities are heavily polluted by cooking emissions. The most significant contributors to poor air quality were poor ventilation and fuel choices, with frying food leading to particularly high levels of indoor pollution.

SourceUniversity of Surrey·JournalEnvironment International·TypeData/statistical analysis·DateMar 16, 2022

The early pandemic’s effect on engineering students’ learning

The study found that while some students felt a sense of loss due to limited access, others saw the challenge as an opportunity to problem-solve and build flexibility. The researchers emphasize the importance of interpersonal relationships and instructors' resources in enhancing educational experiences.

SourcePenn State·JournalJournal of Engineering Education·DateMar 16, 2022

Scientists from Korea’s KIMM and NTU Singapore devise new technique to increase chip yield from semiconductor wafer

A new chemical-free printing technique has been developed by Korean and Singaporean researchers, resulting in highly uniform and scalable semiconductor wafers with improved performance. The technique, which combines nanotransfer-based printing with metal-assisted chemical etching, offers a promising solution to the global chip shortage...

On the brink of giving up? Scientists confirm mindfulness meditation can help in internal conflicts

A study by researchers at the University of Quebec in Montreal found that mindfulness meditation can help people cope with internal conflicts. The experiment involved 121 volunteers who underwent either a mindfulness body scan or read magazines for 15 minutes, then completed a questionnaire about their emotional state.

SourceThe Polish Association of Social Psychology·JournalSocial Psychological Bulletin·DateMar 16, 2022

Sustainably sourcing coal waste

The project aims to find efficient ways to use graphene particles from domestic coal wastes in Fused Deposition Modeling (FDM) 3D printing, increasing the carbon content of filaments and developing new materials. This technology could lead to a more sustainable future by reducing greenhouse gas emissions.

A fresh perspective on Picket-Spengler reaction with α-ketoesters as a new carbonyl source

Researchers from Nagoya Institute of Technology have successfully demonstrated the first enantioselective Pictet-Spengler reaction of acyclic α-ketoesters with tryptamines, achieving high yields and enantioselectivity. The study expands the scope of the process, which could accelerate drug development.

SourceNagoya Institute of Technology·JournalOrganic Letters·TypeExperimental study·DateMar 16, 2022

Using Artificial Intelligence to solve one of health care’s most enduring problems

Incidental imaging findings in medical imaging studies are often overlooked by providers, leading to delayed and missed care. Northwestern Medicine's AI-powered system identifies these findings and triggers alerts for follow-up, improving patient outcomes. The system has been shown to flag over 68,000 lung finding occurrences per year.

SourceNorthwestern Memorial HealthCare·JournalNEJM Catalyst·DateMar 16, 2022

‘Self-driving’ lab speeds up research, synthesis of energy materials

Researchers at NC State University have developed a 'self-driving lab' that uses artificial intelligence and fluidic systems to advance our understanding of metal halide perovskite nanocrystals. The technology can autonomously dope MHP nanocrystals, adding manganese atoms on demand, allowing for faster control over properties.

SourceNorth Carolina State University·JournalAdvanced Intelligent Systems·TypeExperimental study·DateMar 16, 2022

Novel theory of entropy may solve materials design issues

Researchers at Penn State have developed Zentropy theory, a new approach to understanding entropy that can predict anomalies in physical properties like volume. The theory may lead to breakthroughs in designing superconducting materials and structural materials that withstand higher temperatures.

SourcePenn State·JournalJournal of Phase Equilibria and Diffusion·DateMar 16, 2022