A new study published in Nature Communications finds that a protein called saxiphilin can neutralize the potent neurotoxin saxitoxin, preventing and even reversing paralytic shellfish poisoning. The discovery could have important public health implications as saxitoxin accumulates in shellfish and causes poisoning when consumed.
Researchers estimate that audience travel is responsible for most emissions at 'mega-events' like the World Cup. To reduce emissions, organisers should reward fans with discounts for using lower-carbon transport, rather than passing on costs.
Researchers analyze the 'ringdown' phase of black hole collisions to test Einstein's theory of General Relativity and uncover secrets about these mysterious objects. Future observatories may reveal fresh evidence for new physics and challenge current models.
A study identified four major symptom patterns in women with endometriosis, revealing a more complex picture of the disease. The research found that psychological and neurological symptoms are common in active disease, while some patients may experience a lower symptom burden.
Researchers found that certain sweeteners, such as isosteviol, impaired two important gut bacteria linked to regulating blood sugar and gut health. The study suggests that artificial sweeteners can directly affect gut microbes, particularly when mixed with other substances.
Researchers at Hiroshima University have developed a new way to detect subtle, early-stage changes in human skin collagen using advanced optical imaging and chiroptical spectroscopy. The study reveals that the molecular organization and supramolecular chirality of dermal collagen collapses prior to visible fiber thinning or fragmentation.
A study of 9,996 participants found that 76.9% of smokers buy legal tobacco, while 23.1% purchase from illicit sources at least once a year. Illicit markets are often driven by financial pressures and switching to cheaper products or quitting smoking.
A new study reveals that CDK8 helps plants allocate sulfur for growth and defense by regulating the use of sulfur in molecular machinery. Plants can switch between high-sulfur and low-sulfur defense strategies, conserving sulfur when necessary, to maintain immunity.
Researchers developed a programmable virtual metasurface that converts invisible infrared images into visible light while dynamically controlling focus. The system uses software-defined optical patterns and can be reconfigured in real time, offering a new approach for infrared imaging and wavefront control.
Researchers investigated potential locations for small-scale ammonia plants using electrolysis, which could reduce emissions and dependence on global supply chains. Hybrid plants combining local renewable energy with grid electricity perform best, offering a more economical solution.
Researchers identified a key driver of liver fibrosis progression: FSP1+ macrophages that activate PGK1 through lactylation. This self-reinforcing loop amplifies glycolytic signaling, promoting liver fibrosis. A cell penetrating peptide targeting PGK1 lactylation blocks fibrosis progression in preclinical models.
Researchers found that aged mice brains show increased micronuclei, which microglia internalize, leading to changes in morphology and gene expression. This process may contribute to age-associated inflammation and vascular dysfunction.
Researchers discovered branched O-mannose glycans play a crucial role in maintaining nodes of Ranvier and efficient nerve signaling. The study found that these sugar structures help preserve the narrow architecture required for fast and reliable communication.
Researchers developed a new class of optical storage technology that combines phase-change materials with responsive hydrogels for full-color image multiplexing. The device offers robust rewritability and can be controlled using environmental conditions, enabling user-friendly and secure data encryption.
A new study in Nature Communications reveals a hidden source of antibiotic resistance in Australian soil. The mcr-12 gene was found in contaminated freshwater sediment and provides bacteria with resistance to polymyxin, a critical last line antibiotic.
Researchers have identified a protein called vitronectin that triggers the scarring in lungs leading to idiopathic pulmonary fibrosis. This discovery opens up a new potential treatment pathway using the vitronectin-macrophage pathway to inhibit scar tissue growth.
Researchers presented a comprehensive system-level review of polymer-based flexible wireless sensors for seamless skin-like mechanical compliance with real-time health monitoring. The review breaks siloed tradition by addressing sensing mechanisms, wireless systems, manufacturing strategies, materials, and clinical applications.
Researchers from Tianjin University and Lund University developed a pioneering in-cylinder active reduction strategy to combat high NOx emissions from ammonia-fueled internal combustion engines. The study successfully reduced NOx emissions by 14.4% using an ammonia post-injection technique.
Researchers have developed a novel hierarchical hydrogel electrolyte that balances mechanical robustness and ionic conductivity, enabling ultralong-life flexible zinc-ion batteries with impressive performance. The bioinspired design achieves exceptional ionic conductivity and accelerates Zn2+ desolvation kinetics.
Researchers unveil high-performance, earth-abundant Fe-N-C catalysts using AI and quantum chemistry. The 'dual modulation' strategy accelerates oxygen reduction reaction in fuel cells, enabling cheaper and more efficient hydrogen fuel cells.
UCSF Health Converge accelerates development of AI tools for real-world care delivery by co-developing solutions with select companies. The program focuses on building patient-centered, clinically effective AI solutions that align with UCSF Health's standards.
SFU's significant reduction in greenhouse gas emissions is a result of decades of strategic energy management, infrastructure investment, and collaboration with external partners. The university's progress builds upon its commitment to resilience and sustainability, values reflected in its 'What's Next: The SFU Strategy'.
Sylvester researchers develop AI-powered fracture prediction models, train as wildland firefighters to reduce cancer risk, and discover new targets for pancreatic cancer treatment. A new tumor-on-a-chip model shows how pancreatic cancer hijacks immune cells.
A Mayo Clinic-led study found that continuing maintenance therapy beyond two years did not improve overall survival for patients with standard-risk multiple myeloma. The findings suggest that treatment duration can be safely tailored, reducing treatment burden and costs.
A team of researchers from Saitama University has discovered a natural peptide aptamer called Calmodulin-binding peptide (CBP) that can selectively recognize two structurally distinct proteins, calmodulin and human midkine. CBP binds to calmodulin in the presence of calcium ions and to human midkine in the presence of sodium ions.
A research team used a simple physical model to connect sublattice melting with cooperative and spatially heterogeneous ion transport, revealing a fundamental mechanism behind superionic conduction. The findings offer a unified explanation for this phenomenon, which could guide the design of next-generation solid-state batteries.
A new study from UT Health San Antonio found a link between long sleep hours and higher levels of an Alzheimer's-related protein in the blood. The research suggests that long sleep may reflect early neurodegenerative processes, but more sleep is not always better for brain health.
Researchers argue that social media restrictions should be viewed as part of a complex system rather than isolated policies. They suggest using systems mapping to anticipate effects and design more balanced approaches, considering factors such as school engagement, social connections, and industry responses.
A systematic review and meta-analysis found that weight loss drugs can reduce key symptoms of binge eating disorder, including binge eating episodes, loss-of-control eating, and emotional eating. The study suggests that these medications could be an important part of treatment plans for people with binge eating disorder.
A study found that Black African and Caribbean women in the UK are less likely to attend breast cancer screening due to limited knowledge and trust issues with healthcare providers. Researchers recommend stronger links between GP practices, breast screening services, and community champions to improve awareness and attendance.
KAIST develops robot that can autonomously choose gait strategy for its surroundings, switching between walking, running, jumping, and other locomotion skills. The team generated 15.5 hours of training data using computer simulations alone, enabling the robot to move quickly and stably in real outdoor environments.
Researchers analyzed data from over 500,000 births in Scotland to examine the effects of epidural analgesia on newborn health. The study found no association between epidural use and serious neurological conditions, sepsis, or cerebral palsy in childhood.
Data shows Black doctors are up to 30 times less likely to be offered medical training posts, with some specialties seeing a gap of over 100-to-1, while Asian applicants face similar challenges. The findings highlight ongoing barriers faced by ethnic minorities in the UK health service.
Researchers developed an analytical technique to evaluate culture media quality by analyzing patterns of fluorescence from synthetic polymer probes. This technology detects quality differences in serum, stem cell, and microbial cultures with high precision, improving reproducibility.
Researchers are engineering biochar-based composites to overcome limitations, such as insufficient adsorption capacity and limited selectivity for certain emerging pollutants. The new review highlights the importance of balancing treatment performance with environmental safety throughout the material's life cycle.
A condition affecting 170 million adolescents and women worldwide is being redefined to capture its complexity, including its far-reaching health impacts on metabolism, mental health, and reproductive systems. The proposed name change aims to improve awareness among patients and providers, encouraging more comprehensive care.
A new study uses machine learning to predict chemical toxicity in rare and endangered species, reducing the need for direct biological testing. The model achieved strong performance predicting acute and chronic toxicity, with life stage being a key factor.
A new study reveals that carefully designed power cycles can convert more of LNG's overlooked resource into useful electricity. Researchers found that a two-stage Rankine cycle with reheating produces the most effective design, generating up to 9.2 megawatts of net power.
The ECOG-ACRIN ENDURANCE trial found that indefinite lenalidomide maintenance had no survival benefit and more toxicity compared to stopping treatment after 2 years in patients not undergoing a stem cell transplant. The study suggests that fixed duration treatment can significantly reduce healthcare costs.
Researchers at Texas A&M University have found a way to intervene early in traumatic brain injuries using a natural, gut-derived chemical that prevents post-traumatic epilepsy from taking root. The treatment reduced brain inflammation, improved memory and mood, protected brain cells, made seizures both rarer and harder to trigger.
Scientists harness non-Abelian anyons to perform any operation a quantum computer needs, eliminating the need for expensive magic state distillation. The approach enables fault-tolerant computations and has potential applications in quantum error correction and basic physics research.
A new study from the University of Washington highlights the potential consequences of losing roadless protections on rivers and drinking water supply. The study found that over 80,000 miles of rivers receive some protection from the rule, reaching 25 million people across the country.
Scientists at MD Anderson Cancer Center have identified a previously unknown mechanism by which T cells attack and eliminate acute myeloid leukemia (AML) cells. The discovery reveals that AML cells use a CD64-dependent pathway to evade traditional MHC recognition, potentially explaining why AML is sensitive to immune-based treatments.
A recent study published in Neurology found that Black individuals born outside the US have a significantly lower risk of stroke compared to those born in the US. The study, which analyzed data from over 64,000 adults, also found that immigrants who arrived within 15 years of the survey had a 73% lower odds of stroke.
A study reveals that forests and rivers work together to strengthen amphibian microbiomes and protect them from a deadly fungus. The research found that disconnected habitats impair the ability to recruit defensive microbes.
A pair of studies by NYU psychology researchers found that teaching leadership is not an innate trait and encouraging diverse mental representations of successful leaders can significantly increase teens' sense of belonging in leadership roles. By changing young people's views on leadership, the research suggests strengthening ambition...
A study found that college students who spent more time online and experienced online harassment were more likely to report suicidal thoughts. Cisgender men showed the strongest link between time spent online and suicidal thoughts, while online harassment was linked to higher risk across all gender groups.
The Perseverance rover has discovered evidence of repeated asteroid impacts creating a 3.9-billion-year-old 'weather report' from early Mars, preserving a record of variable-sized impacts and potential interaction with water or ice. The findings offer insights into one of the most turbulent chapters in the solar system's history.
A new study finds that most Americans view illicit drugs as a serious national problem, but perceive little progress in addressing it. Perceived progress on drug policy is strongly linked to political affiliation, with Republicans and Democrats having starkly different views.
A rare case report highlights the challenges of diagnosing cervical angioleiomyoma, a benign tumor presenting symptoms similar to those of common gynecological conditions. The study describes a successful surgical excision and excellent clinical outcome for a young woman with persistent heavy menstrual bleeding and pelvic pain.
New research reveals altitude-dependent carbon storage mechanisms in diverse forest ecosystems. High-altitude conifer forests excel at storing carbon in biomass, while lower-elevation mixed broadleaf forests stabilize soil carbon. Effective forest management requires altitude-specific approaches to conserve biomass and enhance soil org...
Canadian agri-food leaders recommend strengthening food infrastructure, improving preparedness, and building resilience to protect against geopolitical threats, biological threats, trade disruptions, and supply chain vulnerabilities. The report outlines seven key recommendations to ensure Canada's long-term food resilience.
Researchers at St. Jude Children's Research Hospital discovered that smaller sub-compartments within the nucleolus form to finish the final steps of ribosome assembly. These sub-compartments lock major ribosome building blocks together until they are assembled, preventing a key protein from associating with them prematurely.
A new award will help advance the proof-of-concept work toward commercialization of an at-home HIV test that detects cases not caught by lab tests. The device, called Click Chemistry Amplified Nanopore (CAN) sensing, has shown promising results in early studies.
The University of Minnesota Medical School research team has received a $10 million NIH grant to study how animals fight infection. The team will utilize a 'cellular zoo' of living cells from over 100 animal species to understand how different species recognize and respond to viral infections.
Scientists have found a way for the circadian clock to produce a winter version, which can suppress reproduction and alter activity patterns in fruit flies. This discovery could lead to new ways to disrupt pest populations and improve human health by better understanding seasonal influences.
The 24hreview initiative presents a standardized, shared pre-submission integrity layer for the global academic publishing community. The platform has already piloted its approach with Wiley and seen reliable verification of manuscript integrity within 24 hours.
Scientists have unveiled a new structure of the kinesin-1 protein, showing how cells control its on-off switch. The discovery could shed light on incurable neurodegenerative diseases such as ALS and Charcot-Marie-Tooth Disease Type 2.
Researchers developed a hybrid technology combining human learning and machine learning in noninvasive BCIs, producing rapid and sustained gains in motor imagery control. The study demonstrates significant scientific and technological advancement in BCIs, establishing a scalable pathway toward robust neural interfaces.
A new species of colobus monkey, 'Likweli', has been identified by its distinctive facial markings and unique call. The rare species is found in the dense forests of Lomami National Park and is considered Endangered due to its small geographic range and population size.