Researchers found that widespread flooding in the Middle Yangtze Valley led to the decline of the Shijiahe culture around 4,200 years ago. The study used stalagmite analysis to reconstruct rainfall patterns and show that high-rainfall intervals were associated with increased flooding and a significant decline in population.
Washington State University researchers identified a critical region in the leiomodin protein that regulates filament length, essential for maintaining a healthy heartbeat. The discovery may hold clues to future treatments of cardiomyopathies and other heart conditions.
The FAU project will integrate high-resolution modeling, observational data, and advanced machine learning to improve understanding of regional sea-level variability in the Gulf of America. The team aims to produce decision-relevant scenario outputs and empower stakeholders with actionable information for future-oriented decisions.
This study investigates the clinicopathologic features and genomic landscape of DNA polymerase epsilon mutant colorectal adenocarcinomas. The analysis reveals two distinct subgroups with different outcomes, suggesting improved prognostication for some patients.
Research from Princeton University reveals that nations globally underreport greenhouse gas emissions from wastewater facilities by up to 27%. Accurate estimates are crucial for sound public reporting and practical decision-making in the wastewater sector. The study finds that wastewater systems offer strong options for emissions reduc...
A new study found that flexible school start times can significantly improve teenagers' sleep patterns, reducing chronic sleep deprivation and its negative effects on mental health. Under a new model with flexible start and end times, students were able to get up 40 minutes later and slept an average of 45 minutes longer on school days.
Researchers developed a new suite of neuropsychological tests suitable for Mandarin-speaking older adults, accounting for Chinese characters and cultural nuances. The tests show high stability and strong links to novel Alzheimer's disease biomarkers.
A pediatric investigation study reveals a two-way association between teen fitness and confidence, highlighting the importance of holistic youth health strategies. The study found that cardiorespiratory fitness, strength, and self-efficacy mutually reinforce each other during adolescence.
A phase 3 trial found that orforglipron, a novel GLP-1 receptor agonist pill, leads to greater blood sugar control and weight loss than current oral GLP-1 RA semaglutide in people with type 2 diabetes. Participants taking orforglipron had significantly greater reductions in body weight and blood sugar levels.
Researchers at the University of Basel have developed a new laser profile that enables deeper and faster cuts in hard tissues like bone. The top hat profile distributes energy more evenly, overcoming limitations of traditional laser systems and enabling joint implants and custom-made 3D-printed implants.
A new book chronicles the impact of immigration enforcement on young adult families, revealing a geography of deportability where no space feels safe. The research highlights the pivotal role of young adults in coping strategies, including emotional labor and navigating legal processes, amidst rising mental health concerns.
Researchers at the University of Southern California Health Sciences have discovered a new treatment approach that combines laser heat therapy with immunotherapy to improve survival rates for patients with high-grade astrocytoma. Nearly half of patients treated with this combination were still alive after 18 months, exceeding the typic...
Researchers from Rutgers University found that melting glaciers in Antarctica supply far less iron to surrounding waters than previously thought. The study challenges the long-held theory of iron fertilization, which suggested that glacial melting would feed blooms of microscopic algae and remove heat-trapping carbon dioxide from the a...
Researchers have identified a unique protein named Aurora-related kinase 1 (ARK1) essential for the malaria parasite's survival and transmission. Turning off ARK1 in the lab causes replication to fail, preventing disease progression and transmission.
A team at The University of Osaka has identified a signaling molecule called FGFR3 and a pathway called CREB as key in regulating bone growth. Cells carrying the genetic mutation associated with achondroplasia accumulate in the resting zone and show abnormal behaviors, which included abnormal patterns of division and migration.
A new study found that heart attack deaths rose by 1.2% among adults under 55, particularly women who were more likely to die from a severe form of the condition. The research highlights the need for earlier risk identification and consideration of non-traditional risk factors to improve treatment.
A team of scientists, led by Associate Professor Jiangtao Cheng, has discovered a previously unreported method to get a puddle of water up to 1 cm wide to jump into the air. The bursting energy of bubbles trapped inside the droplets is key to this phenomenon.
A new 11-year study found a clear link between wildfire smoke pollution and an increase in violent assaults in Seattle. Exposure to short-term wildfire-driven air pollution was linked to a 3.6% rise in daily assaults.
Scientists have developed a new catalyst that uses sunlight to break down polyfluoroalkyl substances (PFAS), a group of water-repellent chemicals linked to increased cancer risk. The technology could be scaled up for detection or removal from the environment and human body.
Researchers in the EU project SUPREME are working on a PFAS-free electrolysis technology that can produce green hydrogen more sustainably and efficiently. The team is developing alternative materials to replace iridium, aiming to reduce its use by up to 75% and recycle 90% of it.
The CEBE program aims to develop new knowledge and solutions to reduce the climate impact of construction. The program will focus on seven research fields, including assessing and measuring sustainability, and collaborate with international partners.
A two-year study found that small household solar power systems have limited capacity, typically only 6 watts, which does not deliver meaningful energy services. Households with access to higher-capacity systems (50+ watts) reap the most direct benefits and are more likely to adopt additional solar components.
Researchers found that perfluorononanoic acid (PFNA) and perfluorooctanesulfonamide (PFOSA) accelerate biological aging in middle-aged men, with effects being strongest in this age group due to lifestyle factors. PFAS pollution has been linked to human cancers, obesity, infertility, and hormonal imbalances.
Researchers at Osaka Metropolitan University found that targeting the glutamine transporter ASCT2 can suppress cell growth and induce apoptosis in synovial sarcoma cells. This study suggests a new approach for treating this aggressive malignant tumor by cutting off its nutrient supply.
Research highlights the challenges of managing an early-onset cardiovascular condition while raising younger children, including uncertainty about communicating with children, physical and emotional strain on daily life, and heightened awareness of potential genetic risks. The study emphasizes the need for developmentally appropriate c...
Researchers have discovered a 3,000-year genetic link between the Old Irish Goat and ancient goats living in Ireland during the Late Bronze Age. The study sheds light on the breed's remarkable continuity and highlights its importance as a living piece of Ireland's ancient heritage.
Researchers at Adelaide University have developed a world-first cybersecurity system to protect drones from hacking, signal disruption, and malicious software. The system uses Software-Defined Wide Area Networking (SD-WAN) to act as a smart traffic controller for internet connections, making drones less vulnerable to cyber threats.
A new study suggests climate models may underestimate natural variability in monsoons, leading to an earlier detection of human-caused changes. Researchers used 'super-simulations' to analyze 550 climate models and found that projection uncertainty stems from model differences and internal variability.
Researchers developed a rapid and non-destructive method to monitor iron flux in mesenchymal stromal cells (MSCs) using micromagnetic resonance relaxometry (µMRR). This breakthrough enables real-time insights into MSC's ability to form quality cartilage tissue, paving the way for more consistent manufacturing of MSC-based therapy.
A recent study analyzed environmental DNA from the largest global dataset of arbuscular mycorrhizal fungal and found a striking gap: more than 70% of ecoregions lack sequencing data. This underrepresentation threatens biodiversity surveys, plant productivity, soil aggregation, and climate mitigation predictions.
A new study shows that exercise during chemotherapy measurably improves quality of life for women with breast cancer, with benefits consistent across physical, emotional and mental health domains. The findings support existing clinical guidelines and provide clarity on the effectiveness of exercise interventions during treatment.
Researchers at Tohoku University's Advanced Institute for Materials Research developed distortion-resistant energy materials for lithium-ion batteries, improving efficacy and cost-effectiveness. The cathode design utilizes 'interfacial orbital engineering' to neutralize Jahn-Teller distortions, achieving near-perfect cycling stability.
A team of scientists at the University of Sydney has discovered how three naturally occurring antibiotic compounds disrupt the ClpC1–ClpP1P2 complex, a vital protein degradation machine in Mycobacterium tuberculosis. This finding uncovers surprising complexity and provides valuable insight into designing more effective anti-TB treatments.
Researchers identified three master regulator genes on chromosome 21 that disrupt normal brain activity in individuals with Down syndrome. Overactivating these genes was linked to disruptions in hundreds of other genes involved in learning and memory, providing new insights into the condition.
Daily aspirin use offers no quick or reliable way to prevent bowel cancer in the general population, increasing risk of serious bleeding. However, it may have potential long-term benefits for people at high genetic risk of colorectal cancer.
Researchers at Kobe University found that liverwort's hair-like rhizoids take in and transport phosphorus to its tissues, contrary to initial assumptions. This discovery sheds light on the evolution of nutrient acquisition mechanisms in simple land plants like mosses and liverworts.
Research at Flinders University found that a thinking style known as systemising, which seeks patterns and consistency, can lead individuals to believe in conspiracy theories despite good scientific reasoning skills. This cognitive style can make it difficult for people to update their beliefs when faced with new evidence.
The Baskerville National Compute Resource (NCR) will benefit researchers in various disciplines with advanced data processing capabilities. The facility harnesses accelerator technology to process vast amounts of data at incredible speed, helping researchers achieve breakthroughs faster than ever before.
A new study by Harvard T.H. Chan School of Public Health and the Department of Veterans Affairs Boston Healthcare System found that using GLP-1 receptor agonists in combination with adhering to healthy lifestyle habits significantly reduces cardiovascular risk among individuals with type 2 diabetes. The study showed that these two stra...
As climates become more extreme, traditional building designs are failing to keep people safe and comfortable. A new generation of architects is creating climate-ready buildings that can maintain comfortable temperatures independently from the grid, using local natural resources like sun, wind, and ground-sourced energy.
Researchers from the University of Oxford have resolved a long-standing debate about the Moon's magnetic field, finding that it had an extremely strong field at times but was mostly weak. The new analysis suggests that the Apollo samples were biased to record rare events, leading scientists to overestimate the field's strength.
Only 6 of every 10 finalised post-authorisation studies uploaded protocols and less than 7% had results available for EMA's database. This lack of transparency hinders scientific review and research credibility.
Researchers found that children who aren't friends connect better through play when given a task to complete, especially during goal-directed activities. The study, which involved 148 children aged six to eight, shows that connected communication is crucial for social coordination and teamwork.
A new study published in Global Ecology and Conservation found that released animals, like Bengal slow lorises, are at risk of being attacked by territorial peers. Only two out of nine released animals survived, with the others dying due to fatal attacks.
A nationwide study in Sweden found that HPV vaccination significantly reduces the risk of invasive cervical cancer, with sustained protection observed for 13-15 years after vaccination. The study also showed a population-level decline in cervical cancer cases over time.
A new study published in Cardiovascular Research found that a single night of road traffic noise can cause stress to the heart and blood vessels, impairing blood vessel function and raising heart rate. The study also showed changes in inflammation and stress responses linked to nighttime noise exposure.
Scientists have discovered how engineered biochar and microbes work together to enhance phytoremediation by improving soil conditions and stimulating beneficial microbes. The study found that modified biochar substantially increased plant growth, boosted photosynthesis, and promoted the transfer of cadmium from roots to stems and leaves.
A randomised control trial conducted on 587 gay and bisexual men found no effect of the meningococcal B vaccine (4CMenB) on preventing gonorrhoea. The study's results suggest that alternative prevention methods, such as condoms and regular testing, are necessary to combat the rise in antibiotic-resistant gonorrhoea strains.
Mayo Clinic has been ranked as the No. 1 hospital in the world for its eighth consecutive year by Newsweek, based on patient survey results and key performance metrics. The organization is transforming healthcare through its Bold. Forward. strategy, which combines deep clinical expertise with responsible digital innovation.
A new review highlights how engineering biochar with magnetic and mineral modifications can expand its environmental applications while overcoming practical limitations. Engineered biochars combine adsorption with reactive processes to trap pollutants, transform or degrade them, reducing the risk of secondary contamination.
The AAO-HNSF is developing evidence-based tools to address hearing loss, vestibular dysfunction, and fall risk in older adults. The project aims to equip otolaryngologists with specialty-specific tools to improve care quality and empower patients to have more meaningful conversations.
A team of environmental chemists developed a new catalyst made from discarded coffee grounds that efficiently removes hydrogen sulfide, a highly toxic industrial gas, while producing elemental sulfur. The material was produced through a two-step process and demonstrated outstanding performance during laboratory testing.
A global team of scientists, led by University of Houston microbiologist Madhan Tirumalai, has identified the critical role of biofilms in human space exploration. Biofilms could influence astronaut health, drug delivery and space agriculture, while also posing risks to astronaut health.
The study found that telemedicine patient visits were billed $400 less and resulted in fewer follow-up visits compared to in-person appointments. For respiratory symptoms, telemedicine appointments were cheaper by roughly $800 on average, highlighting its cost-efficiency.
A new study reveals that brain rhythms shift attention multiple times per second, affecting focus and increasing susceptibility to distractions. This rhythmic occurrence may help us avoid overfocus on one thing, but also make us more prone to digital alerts and visual stimuli.
A study found that COVID-19 infection significantly increases the risk of acute kidney injury, chronic kidney disease, and kidney failure in US adults. The research used machine learning models to analyze data from over three million patients, revealing a 2.3-times higher risk of acute kidney injury compared to influenza.
A new study published in Neurology found that currently smoking is associated with a lower risk of developing Parkinson’s disease, but quitting smoking was associated with a lower risk of death. Researchers also found that sustained quitters had a 17% lower risk of death compared to persistent smokers.
Researchers found that some membrane-less compartments are built from tiny filaments, revealing new possibilities for therapeutic intervention in diseases such as cancer and neurodegeneration. The discovery suggests that targeting these structures could be effective in treating conditions like ALS and tumors.
The semiconductor industry is shifting from compute to memory as ultra-large AI models demand higher performing chips. SK hynix is increasing bandwidth by a factor of 1.5x every two years, while GlobalFoundries uses AI to improve process control and manage diverse manufacturing processes.
Researchers demonstrated a breakthrough in microrobotics: swarms of magnetic microrobots can manipulate objects without physical contact by harnessing fluid-generated torque. The microrobots act as motors to move millimeter-sized passive objects, opening new pathways for precision manufacturing and biomedical applications.