Researchers identified four distinct brain metastasis subtypes, each with unique immune landscapes and metabolic programmes. The 'Immune-infiltrated subtype' showed high sensitivity to immunotherapy, while the 'Metabolic subtype' responded well to targeted therapies. The study paves the way for personalized treatment strategies.
A team of researchers from Tohoku University's WPI-AIMR has developed a new class of hydrogen storage alloys that can store large amounts of hydrogen while remaining thermodynamically stable. By controlling magnetism, the researchers were able to design materials that combine high hydrogen capacity with good stability.
A new study from McGill University found that a liver-derived protein helps regulate bone growth in male mice, but not in females. The protein, plasma fibronectin, builds up in bones to modulate formation, suggesting men rely more heavily on it for bone strength.
JMIR Publications introduces a new merit-based reward system, Karma, to recognize and reward high-quality peer reviews. The program provides incentives tied to the depth and rigor of feedback, ensuring that reviewers are properly honored for their contributions.
Professor Adelheid Wöhrer discussed innovative diagnostic platforms and collaborative research strategies for better understanding treatment-resistant glioblastoma. Her team is developing a novel diagnostic platform combining Virtual Raman Histology and real-time Nanopore Sequencing to enhance surgical accuracy.
The University of Hong Kong has signed a 5-year partnership agreement with Takatuf Oman's Oman Scholars Programme to support Omani students seeking undergraduate education. The program provides comprehensive funding and enrichment opportunities for eligible participants starting from 2026.
A randomized controlled study found that Transcendental Meditation (TM) significantly reduced perceived stress, anger, and fatigue in Ugandan women. TM also improved sleep quality, self-efficacy, and relationships with family and neighbors.
The Family Heart Foundation, led by Matt Hasselbeck, aims to educate Americans about the risks of high LDL cholesterol and its connection to early heart disease. The campaign promotes free at-home screenings and offers support for individuals to protect themselves and their families from cardiovascular disease.
Researchers at the University of Maryland School of Medicine discovered 25 distinct vaginal microbiome types, challenging the long-standing view of a simplified
Researchers developed a scalable, eco-friendly method to produce chiral perovskite nanocrystal/ethyl cellulose ink with exceptional stability and processability. The new ink enables the fabrication of flexible, high-performance circularly polarized luminescent films and patterns.
Researchers at Case Western Reserve University have made a breakthrough in HIV treatment by enhancing NK cells to better fight HIV infections. The study shows that lab-enhanced NK cells can reduce the viral reservoir enough to allow long-term immunological control of HIV without daily antiretroviral medications.
Insilico Medicine nominates ISM5059, a peripheral-restricted NLRP3 inhibitor, as a preclinical candidate for treating various inflammatory diseases. The compound has demonstrated high potency, selectivity, and excellent in vivo efficacy across animal disease models.
A study led by Cold Spring Harbor Laboratory researchers found that inhibiting the protein PTP1B improves learning and memory in an Alzheimer's disease mouse model. This suggests that PTP1B inhibition can also improve microglial function, clearing up Aβ plaques.
Researchers at Keck Medicine of USC are investigating a unique therapy that uses lab-generated stem cells to repair damaged brain cells and produce dopamine, which may slow down the progression of Parkinson's disease. The treatment has shown promise in early clinical trials with 12 participants experiencing improved motor function.
Researchers developed smart 4D-printed vascular stents that expand naturally at body temperature, eliminating the need for external heating. The stents balance mechanical flexibility and radial strength, demonstrating long-term biomechanical compliance.
Researchers discovered that collaborative care programs improve quality of life, reduce costs, and alleviate caregiver burden for dementia patients. Adding lecanemab to treatment increased healthcare costs but was offset by the savings from collaborative care.
A new study highlights the clinical relevance of brain functional connectome uniqueness in identifying biomarkers for major depressive disorder. Researchers found that patients with MDD displayed reduced FC uniqueness, especially in frontoparietal and sensorimotor networks.
Researchers found that certain types of CD8+ killer T cells are more abundant in people with MS and target the EBV virus, indicating the virus may trigger an immune response leading to progressive neurological damage. The study suggests that interfering with EBV could have a significant impact on other autoimmune diseases.
Researchers developed BrainIAC, a robust AI foundation model that analyzes brain MRI datasets to identify key neurological health indicators. The tool outperformed conventional AI models in diverse tasks, including predicting dementia risk and detecting brain tumor mutations.
Researchers analyzed over 25,000 YouTube comments on wildlife videos to find only 2% calling for conservation efforts. Despite the low number, experts believe there is an opportunity for improved conservation messaging on social media.
A new study by University of Toronto researchers found that day-to-day fluctuations in mental sharpness predict success or struggle. Mental sharpness is linked to productivity, goal-setting, and mood, with sharper days leading to more challenging goals and lower-sharpness days stalling on routine tasks.
Researchers at Graz University of Technology developed a new, more robust insulated joint system to reduce failures and damage on heavily used rail lines. The prototype is expected to double the service life of previous joints and cause lower stresses in the material.
A study from Linköping University in Sweden found no association between COVID-19 vaccination and decreased childbirth rates. Researchers analyzed data on over 60,000 women and found no statistically significant difference between vaccinated and unvaccinated groups.
A new AI-enabled digital stethoscope has been shown to significantly improve the detection of moderate to severe valvular heart disease in routine clinical examinations. The tool achieved a sensitivity rate of 92.3% compared to traditional stethoscopes, enabling earlier diagnosis and potentially reducing complications. By providing an ...
A large Swedish study reveals that rapid growth in startups increases the likelihood of biased hiring decisions, disproportionately affecting women. Founders with HR knowledge and experience counteract these challenges, shrinking gender gaps.
Researchers have been tracking the unusual astronomical event for four years and predict that the energy will peak in 2027. The black hole's emission has increased exponentially, reaching 50 times its original brightness.
Researchers at Chalmers University of Technology have developed a compact, humidity-tolerant sensor that detects hydrogen gas in humid environments. The sensor uses platinum nanoparticles to measure the concentration of hydrogen by analyzing the thickness of a water film on its surface.
A study published in PNAS reveals that Sudanese Copts have acquired a genetic variant that protects them from contracting malaria after mixing with other Sudanese populations. The acquisition of this variant took place over 1,500 years and has led to an evolutionary adaptation to the disease.
Researchers at Osaka Metropolitan University discovered that natto bacteria convert soybean proteins and other substances into supersulfide molecules. Heat-treated soybeans also showed an increase in supersulfides before fermentation, indicating a complex mechanism behind natto's health benefits.
A new study from Tufts University finds that regular family dinners can help prevent substance use among adolescents with low to moderate levels of adverse childhood experiences. However, for those with severe stressors, more targeted approaches like mental health support are needed.
A new Canadian study found that people living with dementia are often excluded from research due to assumptions of incapacity and institutional processes. The study recommends standardized guidance for meaningful inclusion through rights-based approaches.
Recent advances in biomolecular archaeology enable museums to convert molecular data into accessible olfactory recreations. The Max Planck Institute research team developed a workflow for translating ancient chemical signatures into visitor-ready fragrances.
A University of Rhode Island team used Homeland Security exercises to evaluate their storm decision support tool, CHAMP, for improving response to major coastal storms. The exercise simulated the impact of Hurricane Henri on Rhode Island and found that tools like CHAMP can geolocate vulnerabilities and simulate weather hazards.
A new methodology uses photogrammetry and microtopographic analysis to analyze fine engravings in Late Paleolithic portable art, improving the reliability of archaeological interpretations. The technique provides a detailed characterization of groove morphology and variations in depth and width.
A new study found that children growing up in homes with water damage and exposed to high levels of outdoor air pollution have a greater risk of developing asthma. The study also revealed that having a dog during infancy can reduce the risk of asthma in children.
A study published in PLOS Climate found that 41 US states are getting warmer, with regional variation likely to impact agriculture, public health, and climate action. Most states experience warming in specific parts of their temperature distribution, highlighting strong regional inequalities in climate change impacts.
A massive Kamchatka earthquake with a magnitude of 8.8-8.9 struck off the peninsula in 2025, rupturing nearly the same region as a 1952 M9-class earthquake. The study estimated fault slip reached 9-12 m across a broad area, substantially exceeding the accumulated slip deficit since 1952.
ASU researchers use DNA to store and protect information in fundamentally new ways, offering a nature-inspired alternative to silicon-based solutions. The approach uses tiny DNA structures that act like physical letters to record and analyze electrical signals, providing high accuracy and scalability.
Researchers used machine learning to simulate gold nanoclusters' behavior under realistic conditions, revealing structural changes and polymer-like chain formation. The study demonstrates the accuracy of the machine learning potential in understanding nanomaterials' properties.
Researchers developed a new AI control system that allows soft robots to learn a broad set of motions once and adapt instantly to changing conditions without retraining. The system combines structural learning with real-time adaptiveness, making it suitable for diverse tasks and environments.
A study examines how human-AI coexistence is represented in fictional works, revealing varying roles and degrees of autonomy. The findings propose a theoretical model conceptualizing AI as an entity forming relationships with humans.
Researchers developed a novel nanoparticle system to cross the BBB, target infection sites, and release antibacterial agents locally. This strategy effectively disrupts biofilms, eliminates drug-resistant bacteria, and reduces neuroinflammation.
Professor Kazuya Yamagata received the 2025 Erwin von Bâlz Prize Second Prize for his groundbreaking research on pancreatic Ò-cell transcription factors and their role in monogenic diabetes. His work significantly deepens our understanding of β-cell function and diabetes pathophysiology.
Researchers from Hokkaido University used a new method to track groundwater levels and greenhouse gas emissions in Southeast Asia's peatlands, finding they release more gases than previously thought. Human activities like drainage and agriculture increase emissions by tripling or sixfolding, contributing 30% of Japan's annual emissions.
A new catalyst enables efficient and stable electrosynthesis of ethylamine at industrial scale, overcoming long-standing challenges in selectivity loss and instability. The developed method supports continuous energy-efficient production of EA using electricity and water.
A Virginia Tech scientist emphasizes the importance of preserving the nation's ability to turn discovery into life-saving therapies. He argues that strong transparency and careful oversight are key to making the technology-transfer ecosystem work, and that abandoning it could have unintended consequences.
Researchers at Flinders University developed a high-performance coating made from peppermint essential oil that protects against infection, inflammation, and oxidative stress. The coating demonstrates strong antibacterial action against key pathogens, including E. coli and Pseudomonas aeruginosa.
Researchers at the University of California - San Diego have developed a new method to improve gene therapy by increasing the efficacy of gene delivery while minimizing harmful side effects. The new workflow allows for increased control of nuclear DNA delivery, with greater than tenfold increase in nuclear DNA delivery observed.
A study published in Microbiome found that gut microbiome-derived butyrate activates immune cells to enhance vaccine efficacy by promoting T follicular helper (Tfh) cell activity and mucosal antibody production. This discovery highlights the crucial role of gut environment regulation in controlling infections and enhancing vaccine resp...
Researchers at USC's Kanso Bioinspired Motion Lab discovered that sea stars' tube feet respond independently to changing loads, enabling local control strategy. This decentralized approach can optimize robot locomotion and adapt to environmental changes.
A study from Sweden found autism rates among male and female individuals to be comparable, with a clear catch-up effect in females during adolescence. This challenges the long-held assumption that autism predominantly affects males.
A new study reveals that more than 7,000 adult Magellanic penguins were killed by pumas in just four years, posing a significant threat to the penguin population. The research suggests that high puma predation rates could exacerbate reproductive decline and juvenile mortality, ultimately putting the colony at risk of extinction.
Three Illinois Tech engineers recognized for their contributions to sustainable wireless communication and networking. Boris Pervan also received an award for his work on satellite navigation integrity. Thomas Wong honored for his research in high-frequency electronics and materials characterization.
A new study published in BioEssays suggests that humans' increased exposure to high temperature burn injuries may have driven notable genetic adaptations, including faster inflammation and wound closure. These traits helped humans survive small to moderate burns but became harmful for large burns.
Researchers discovered five dominant patterns of protein-altering mutations that determine tumor visibility to the immune system. These 'fingerprints' help predict immunotherapy response and suggest a more personalized approach to cancer treatment.
A study from China finds that testing menstrual blood for human papillomavirus (HPV) can detect cervical cancer with high accuracy, comparable to clinician-collected samples. The non-invasive method allows women to collect samples at home, enhancing feasibility for large-scale implementation.
A new consumer survey shows nearly six in ten Americans still believe only trained individuals should perform Hands-Only CPR. Immediate CPR is proven to improve outcomes, and research indicates it can double or triple a person's chance of survival. To learn more about Hands-Only CPR, visit the American Heart Association website.
The American Heart Association and NFL collaborate to provide Hands-Only CPR instruction during Super Bowl Experience, aiming to double survival rates by 2030. Qualified trainers will be on site, offering walk-up style instruction to the public.
Researchers at the University of Illinois developed origami-inspired waveguides that can be launched in a compact, folded state and expanded to full size after deployment into space. The design aims to improve the efficiency of high-powered satellites by delivering energy from one component to another.
The American Heart Association and the National Football League have selected 136 schools nationwide to receive grants to promote physical activity and well-being for students and faculty. The grants will support four key areas, including physical activity equipment, FLAG football, and well-being resources.