A pilot trial found that PharmaNAC, an antioxidant supplement, reduced irritability and repetitive behaviors in children with autism. The study suggests that PharmaNAC may be a valuable tool to treat these symptoms, which are common in autism.
A Stanford study found that an antioxidant supplement, N-Acetylcysteine (NAC), lowered irritability in children with autism and reduced repetitive behaviors. The researchers believe NAC could be a valuable tool to treat certain features of autism, but further trials are needed.
A Yale University study found that oxytocin increased brain function in regions processing social information in children and adolescents with autism spectrum disorders. This breakthrough may lead to more effective treatments for core social deficits in autism.
Researchers identified 57 single nucleotide polymorphisms (SNPs) associated with an increased risk of autism in siblings of children with Autism Spectrum Disorder (ASD). The study used a combination of statistical and functional genomic data to predict the risk of autism in unaffected siblings.
Researchers at Kennedy Krieger Institute found that infants with weak head and neck control are more likely to develop language and social developmental delays, suggesting a potential early indicator of autism. The study adds motor skills evaluation to existing screenings, improving early detection of developmental delays.
A new University of Miami study reveals that one in three children who have an older sibling with an Autism Spectrum Disorder (ASD) exhibit higher levels of autism-related behaviors or lower levels of developmental progress. Typically developing siblings may face subtle forms of ASD-related problems, such as lower back-and-forth play a...
At the 2012 International Meeting for Autism Research (IMFAR), Autism Speaks presented various scientific findings on autism diagnosis, causes, and treatment options. The organization's Autism Treatment Network shared research on early interventions and technology innovations aimed at improving the lives of individuals with ASD.
The M-CHAT is a scientifically validated tool for screening children between 16 and 30 months to assess their risk for ASD. The automated version now available on the Autism Speaks website offers free online scoring and recommendations, enabling parents to identify potential issues early.
A study found a possible link between smoking during pregnancy and the development of high-functioning autism, including Asperger's Disorder. The research suggests that certain types of autism may be influenced by environmental factors like maternal smoking.
Research identifies specific genetic mechanism underlying autism and fragile X syndrome, suggesting gene dosage disruption as key factor in autism development. The study found a strong overlap between autism candidate genes and those linked to fragile X syndrome, with implications for therapy and diagnosis.
A team at Cold Spring Harbor Laboratory has found a striking association between Fragile-X gene mutations and autism, identifying 60 new candidate genes. The study suggests that these genes are regulated by FMRP, a protein encoded by the Fragile-X gene, which plays a vital role in neural development and synaptic plasticity.
Researchers found that GRN-529 increased social interactions and reduced repetitive self-grooming behavior in mice with autism-like symptoms. The compound also almost completely stopped repetitive jumping in another strain of mice.
A two-year study is underway to identify genetic biomarkers that can predict autism risk in infant siblings. Researchers are examining DNA samples from children with autism and their older siblings to determine if there are any genetic markers that could provide a more accurate estimate of the sibling's risk.
A new study from Washington University School of Medicine found that the genetic reach of autism extends to half siblings, suggesting a central role for genetic mechanisms in transmission. The researchers analyzed over 5,000 families with a child diagnosed with autism and found that half siblings were at higher risk than full siblings.
A new web-based tool has been developed using machine learning techniques to diagnose autism in young children quickly and accurately. The tool uses a short survey of seven questions to achieve nearly 100% accuracy, reducing the time for diagnosis from hours to minutes.
A multi-institutional team of researchers has identified two genes as 'genuine risk factors' for autism spectrum disorders. The study, published in Nature, used massively parallel sequencing to search for mutations that might affect autism risk and found that these genes are functionally related and physically interact with each other.
A recent study published in Nature sequenced exomes of 175 trios with autism spectrum disorder and found many new gene mutations, but few definitive causes. The researchers observed an increased protein-protein connectivity among affected genes and implicated two genes, KATNAL2 and CHD8, as potential risk factor genes.
Researchers identified CHD8, SNC2A, and KATNAL2 gene mutations as risk factors for autism. The studies provide a better understanding of the genetic changes and biological pathways involved in autism spectrum disorders.
A recent study by Yale University researchers found that approximately 15% of autism cases in families with a single autistic child are associated with spontaneous genetic mutations. The study analyzed DNA sequencing data from 238 families and identified hundreds of de novo sequence variations linked to an increased risk for autism.
Researchers found a common network of interactions among genes mutated in children with autism, affecting brain cell formation and signaling. The study also discovered that most new mutations were paternal in origin, correlating with the age of the father.
A DNA sequencing consortium has identified patterns of mutations in autism, highlighting hundreds of genes and pinpointing two specific genes as strong risk factors. The study found that de novo point mutations play a role in the development of autism, with some genes more connected to each other than expected.
Research from Michigan State University found that autistic children born preterm or post-term have significantly higher screening scores for autism spectrum disorder than those born on time. The study also reveals a link between the length of pregnancy and the severity of autism symptoms.
A new CDC report reveals a staggering 78% increase in autism diagnoses over the past six years, with estimated costs of $126 billion annually. Autism Speaks calls for a national strategy to address early diagnosis, treatment, and care for individuals with autism.
Autism has more than tripled in cost since 2006, reaching $126 billion in the US and £34 billion in the UK. The lifetime costs of caring for individuals with autism affected by intellectual disability are significantly higher, up to $2.3 million in the US and £1.5 million in the UK.
A new study published in JoVE demonstrates a method for using eye-tracking technology to study young children with autism. The research aims to answer questions about how children with developmental abnormalities view the world, including their perception of faces.
Autism Speaks has awarded $1.1 million in funding to support research projects focusing on differences between DSM-IV and proposed DSM-5 diagnostic criteria, the impact of flame retardants on immune systems, and strategies to improve quality of life for individuals with autism.
A study published in the Journal of Abnormal Psychology found that people with autism possess a higher capacity for processing information, especially when faced with rapid presentations and distractions. This increased ability can be beneficial in careers such as IT, where intense concentration is required.
The A.J. Drexel Autism Institute will focus on research strategies that address the impact of autism throughout an individual's lifespan, including prevention, intervention, and community approaches. The institute aims to develop effective solutions to reduce morbidity and disability associated with autism.
A global consortium is collaborating on the largest ever academic-industry research project to find new methods for developing drugs for ASD. The EU-AIMS project aims to provide novel validated cellular assays, animal models, and new biomarkers for patient-segmentation or individual response prediction.
A pilot study found associations between parental exposure to certain solvents and an increased risk of autism spectrum disorder (ASD) in their children. The researchers also observed higher levels of asphalt and solvent exposures among parents of children with ASD compared to those without the condition.
Researchers now solidly implicated certain genes as being involved in autism, affecting signal transmission and brain circuits. This breakthrough paves the way for future medications and treatments for autism spectrum disorders.
The study aims to confirm the predictive value of established genetic markers and enroll 600 children over two years. If successful, a genetic test could help identify children with autism earlier, providing beneficial treatment and improved outcomes.
A Swedish register study reveals that children born to certain immigrant groups have an increased risk of developing autism with intellectual disability. The study suggests that environmental factors may contribute to the development of autism, particularly for children whose mothers migrated just before or during pregnancy.
A new study finds that minority toddlers with autism exhibit more delayed language, communication, and gross motor skills compared to Caucasian peers. The research highlights the need for culturally sensitive screening and assessment practices to ensure early detection and intervention.
The Autism Treatment Network has released two new tool kits: Sleep Strategies for Children with Autism and Treating Children with Autism Spectrum Disorders. The guides provide families and dental professionals with effective strategies to improve sleep quality and oral health, respectively. By implementing these tools, families can cre...
Researchers from the UC Davis MIND Institute will present on the relationships between genetic, epigenetic, and environmental influences on autism development. Their research highlights the impact of flame retardant chemicals on autism risk, particularly in female offspring.
Researchers discovered significant brain differences in infants as young as six months old who later develop autism. Infants with autism showed changes in white matter pathways, which may be used to diagnose the disorder earlier.
A study found differences in brain communication pathways as early as 6 months in infants who later received a diagnosis of autism. The researchers used magnetic resonance imaging to evaluate the brains of 92 infants, including those with older siblings on the autism spectrum. This study offers promise for identifying infants at risk f...
A new study found significant brain differences in high-risk infants who later developed autism, starting as early as 6 months. Infants with autism had elevated white matter fiber tract development at birth, but slower growth over time, suggesting potential early interventions.
Researchers discovered significant brain development differences in 6-month-old high-risk infants who later developed autism compared to those who did not. Infants with autism showed elevated white matter fiber tract development at 6 months, followed by slower changes over time.
A recent study of 56 children with autism spectrum disorders found no statistically significant correlation between urinary mercury levels and autism. The researchers suggest that mercury excretion rates are unlikely to have a clear causal link to autism spectrum disorders.
A study published in Autism found that 83% of children with autism spectrum disorder were below average in motor skills, while their siblings scored in the normal range. The researchers suggest that genes play a role in these impairments, potentially explaining the association between motor coordination and social responsiveness.
A recent study published in the Journal of Autism and Developmental Disorders found a joint association between maternal and paternal age and autism risk. Mothers with autistic children were on average 6.5 years older than non-autistic women, while fathers had an average age difference of 5.9 years.
Researchers found that adults with moderate to profound learning disabilities have a higher likelihood of having autism. The study revealed that about 60% of men and 43% of women with severe learning disabilities have autism, emphasizing the need for improved services and training for staff.
Researchers have identified differences in brain function that may predict future autism symptoms in infants as young as six months old. The study found that these early brain responses associate with a later diagnosis of autism, suggesting direct measures of brain functioning could aid in predicting the development of autism symptoms.
The grant will explore the environmental factors influencing autism risk through epigenetic changes in DNA methylation. Autism Speaks aims to uncover avoidable risks and provide guidance for earlier diagnosis and improved treatments.
A new study published in Psychological Medicine found that low birth weight is an important environmental factor contributing to the risk of autism spectrum disorder (ASD). The researchers used a unique study design involving discordant twin pairs and found that lower birth weight more than tripled the risk for autism.
A study published in mBio found that children with autism and gastrointestinal symptoms have high levels of the bacterium Sutterella in their intestines. The researchers detected Sutterella species at remarkably high levels, which may play a role in the development of gastrointestinal disturbances in children with autism.
The new treatment section provides insight into different treatment options for children with autism, including behavioral interventions and clinical therapies. Families can view examples of treatment in action to help determine the best course of treatment for their child.
A study by University of South Florida researchers found that elevated levels of an amyloid precursor protein fragment in the blood may explain aberrations in immune cell populations and function. The findings suggest that the protein fragment could be both a biomarker for autism and a new research target.
Autism Speaks has awarded 47 new research grants, totaling $13.2 million, to advance understanding of epigenetic and gene-environment influences, neurobiology, and studies on adolescents and adults with autism. The grants will focus on increasing early diagnosis, improving treatment outcomes, and reducing the economic cost of autism.
The NDAR federation has created the largest source of autism research data to date, providing a standardized platform for collaboration and data sharing. Researchers can access results from various sources simultaneously, conducting independent analyses and supplementing their own research data.
Autism Speaks has joined the National Institute of Health's National Database for Autism Research (NDAR), providing access to genetic, phenotypic, and clinical data from 2500 families. This collaboration enables researchers to pool larger datasets and accelerate scientific discovery.
A new study by Michigan State University researcher Brooke Ingersoll found that teaching imitation skills to toddlers and preschoolers with autism improves key areas of deficit, such as eye contact and gestures. The findings come at a pivotal time in autism research, which is detecting behaviors and symptoms earlier than ever before.
The new tool kit provides valuable guidance on utilizing pictures and visual supports to facilitate daily communication, social interactions, and adaptation to new situations. It has been found to decrease challenging behaviors and increase compliance and independence in families who use it.
A study by UC Davis MIND Institute researchers found that 3-year-old boys with regressive autism have larger brains than their healthy counterparts, while girls with autism do not show abnormal brain growth. Brain enlargement was consistently observed only in the subset of children diagnosed with regressive autism.
The Royal Arch Masons have awarded a $100,000 grant to Autism Speaks to investigate auditory processing disorders in children with autism. The grant aims to create better outcomes for children at risk of developing both ASD and CAPD by addressing precursor symptoms of auditory processing disorders.
A new study found that autism diagnoses vary significantly across different clinical centers, with varying use of subcategories like Asperger syndrome. The research suggests that a more standardized approach to diagnosing autism spectrum disorders would provide more accurate and consistent information about individual patients.
A preliminary study found that children with autism had an average 67% more prefrontal brain neurons and a larger than average brain weight compared to children without autism. The researchers also discovered significant differences in neuron counts in the PFC, with 79% more neurons in one subdivision.
A recent NIH-funded study found that children with autism have more brain cells and heavier brains compared to typically developing children. The researchers suggest that faulty prenatal cell birth or maintenance may be involved in the development of autism.