Researchers have identified a possible mechanism used by an important motor protein that enables bacteria to travel through the bloodstream and infect organs such as the heart. The discovery may lead to the development of new pharmacological therapies that can target and kill bacteria, preventing or minimizing damage to the heart muscle.
Researchers used X-ray spectroscopy to observe gold nano-particles' reaction with oxygen and carbon monoxide, revealing the activation mechanism of oxygen. The findings have potential applications in pollution control and hydrogen purification.
Researchers at the University of Virginia Health System developed a new test for peripheral arterial disease (PAD) using MR spectroscopy, a technique from the 1970s. The test measures phosphocreatine recovery time in leg muscles after exercise, indicating PAD severity and potential complications.
Walter Wolf, distinguished professor of pharmaceutical sciences at USC, received the award for his groundbreaking work in pharmacokinetic imaging and radiopharmaceuticals. His research focuses on noninvasive studies of drug biodistribution and targeting using nuclear medicine imaging and magnetic resonance spectroscopy.
Using MR spectroscopy improves the detection of malignant breast lesions, reducing the need for biopsy procedures. The technology helps identify tumors with elevated choline compounds, which are a marker of an active tumor, and eliminates the need for biopsies to determine their composition.
The American Institute of Ultrasound in Medicine (AIUM) has awarded several ultrasound research grants to its members through the Educational Enhancement Research (EER) program. The recipients include T. Douglas Mast, PhD for quantitative real-time monitoring of thermal ablation using pulse-echo ultrasound imaging and Roxana Vlad, MSc ...
A new method for identifying bacteria uses genetically engineered phages that infect target bacteria, releasing biotin-capped phage progeny attached to quantum dots. The resulting phage-quantum dot complexes can be detected and counted using microscopy or spectroscopy, allowing for rapid identification of bacteria.
Scientists have found that macromolecular carbon in Martian meteorites is always associated with magnetite, a mineral catalyst for its formation. This association raises hopes that the meteorite's carbon complexes could be evidence of non-biological synthesis of organic molecules on Mars.
Physicists at JILA have developed a highly sensitive tool for real-time analysis of atoms and molecules, offering unprecedented capabilities in chemistry laboratories, environmental monitoring, security, and medical offices. The technology uses an ultrafast laser-based frequency comb to precisely measure light absorption signatures, en...
Robert Downs is almost halfway to creating a library of spectral fingerprints for all the Earth's minerals, with over 1,500 cataloged so far. The associate professor of geosciences is collaborating with colleagues to develop a pocket-sized Raman spectrometer for use on Mars and handheld instruments for identifying gemstones on Earth.
High Energy Density Physics is a new journal launched by Elsevier to publish research on extreme conditions, including planetary interiors and astrophysical phenomena. The journal aims to provide a platform for scientists to study material properties and hydrodynamics under high-energy density regimes.
Researchers use confocal laser scanning microscopy and Raman spectroscopy to analyze ancient microorganisms in Martian rocks, revealing insights into biochemistry and degradation over millions of years. The techniques allow scientists to view fossils in three dimensions, providing new evidence for the search for life on Mars.
A team of Canadian and American scientists reports the first-ever finding of elevated levels of creatine, a newly discovered agent of Alzheimer's, in brain tissue. The study used infrared spectroscopy to detect creatine directly in situ, revealing an overlooked aspect of energy disturbance in Alzheimer's disease.
Scientists have successfully demonstrated a new measurement technique, single molecule absorption spectroscopy, combining optical absorption with atomic-scale resolution of scanning tunneling microscopy. This breakthrough enables the detection of individual molecules under laser illumination.
Researchers developed a new technique using time-resolved laser-induced fluorescence spectroscopy to identify plaque characteristics that contribute to weakening of the plaque. The technique was found to be 97 percent effective in identifying high-risk lesions, which are more likely to rupture and block blood supply.
A Northwestern University study using live-cell time-lapse spectroscopy clearly links the presence of mutant SOD1 protein aggregates with neuronal cell death in ALS. The research provides a new understanding of aggregate structure and composition, offering hope for developing genetic suppressors and therapeutics.
Mark A. Johnson, a Yale professor of physical chemistry, has been awarded the 2006 Earle K. Plyler Prize for Molecular Spectroscopy for his research on water's microscopic scale applications and solvation of protons and hydroxide anions.
The National Science Foundation (NSF) supports six Nobel laureates in chemistry, physics, and economics with its grants. NSF supported Robert H. Grubbs, Richard R. Schrock, Yves Chauvin, John L. Hall, Theodor W. Hänsch, and Roy J. Glauber for their pioneering work on metathesis, laser-based precision spectroscopy, and game-theory analy...
Researchers from NIST and UC Berkeley use NEXAFS spectroscopy to track chemical reactions, molecular reordering, and defect formation in organic electronic devices. The study reveals the importance of film structure and composition on charge carrier movement, offering a new tool for improving device performance.
PNNL scientists employed x-ray spectroscopy to observe the reaction as it occurred, identifying a cluster of four rhodium atoms at the active site. This approach allows researchers to understand catalyst-reactant interactions under practical conditions, shedding light on key catalytic processes.
A new device has been developed to detect inflammatory cells in blood vessels, which are associated with critical atherosclerotic plaques. The device uses fluorescence spectroscopy to identify macrophage infiltration in the fibrous cap, a key marker of plaque inflammation.
MR spectroscopy enhances breast imaging by identifying chemical compounds in tumors, leading to increased cancer detection rates (94-100%) and improved accuracy (57%). This adds value to existing MR exams, reducing unnecessary biopsies and improving patient outcomes.
Scientists at Ohio State University have created a faster method to study the Earth's atmosphere by utilizing laboratory-based spectroscopy techniques. This new approach enables researchers to quickly identify and remove interference signals from molecules in gas systems, leading to more accurate measurements of atmospheric composition.
A new fluorescence device using time-resolved laser-induced fluorescence spectroscopy (TR-LIFS) has been developed to detect atherosclerotic plaque and brain tumors. The technique shows promising results in distinguishing between inflamed and stable plaque areas, as well as detecting tumor cells left behind after surgery.
A study found that analyzing prostate tissue's metabolic profile can identify the biologic status of the disease, allowing clinicians to make better-informed decisions on treatment. The technique outperformed standard histopathology in differentiating between cancer cells and benign cells.
Scientists have developed a new technique to track molecular energy transfer in photosynthesis, revealing distinct energy pathways and quantum mechanical effects. This breakthrough may lead to more efficient artificial photosynthesis systems and sustainable energy sources.
Researchers used point-contact spectroscopy to explore Andreev reflection between a normal metal and a heavy-fermion superconductor. The findings show that conventional theories cannot account for the data, indicating the need for new theoretical frameworks.
Researchers used high-altitude airborne imaging spectroscopy to identify two invading plant species, Myrica faya and Kahili ginger, in the Hawaii Volcanoes National Park. The study found that these invaders are altering the forest ecosystem by changing leaf nitrogen and water content, with potential domino effects on native species.
Scientists developed a high-pressure photoelectron spectroscopy system to study chemical underpinnings of everyday catalytic, biological, and ecological phenomena. They found that negatively charged ions concentrate at the surface of salt grains as they dissolve in water.
Researchers at Vanderbilt University and Pria Diagnostics LLC collaborate to develop a portable device that can quickly detect infectious diseases and biological agents. The device, which aims to produce its first portable HIV monitor within two years, utilizes microfluidic devices and micro-optical fluorescence spectroscopy.
The INEEL-designed Munitions Assessment System processes drums containing multiple chemical munitions, using digital radiography and computed tomography to identify chemical fill. The system also includes portable isotopic neutron spectroscopy for accurate chemical analysis.
A study published in the American Journal of Roentgenology found that increased bone marrow fat is an independent marker of bone weakening. The ratio of bone marrow fat to bone mineral density was higher in healthy individuals and lower in those with signs of bone weakening.
Researchers found significant ethnic differences in NAFLD prevalence, with striking variations among Hispanics, whites, and blacks. Hepatic steatosis was more common in Hispanics and less common in blacks, highlighting fundamental differences in lipid homeostasis.
Researchers have identified significant differences in brain chemistry between people with and without bipolar disorder using MR spectroscopy. The study's findings suggest that this imaging tool may help distinguish bipolar disorder from major depression, improving treatment outcomes.
Researchers at The University of Scranton and the University of Illinois have made groundbreaking discoveries about how molecules interact in nanoscale devices. Using IR Raman Spectroscopy, they measured the pathways for energy transfer across a molecular wall, shedding light on how to design materials that move heat effectively.
Martin Saunders will receive the James Flack Norris Award for his seminal contributions to NMR spectroscopy, structures, and rearrangements of carbocations. He developed new methods for studying these highly reactive species, allowing him to discover detailed mechanisms and rates of rapid rearrangement reactions.
A team of scientists at PNNL has observed real-time interactions between single proteins, supporting the 'fly-fishing mechanism' theory. The technique used, single-molecule photon stamping spectroscopy, allows for dynamic measurements of protein dynamics.
Comet composition can be studied for the first time using a new technique, providing insights into the early solar system. Carbon disulfide has been detected in comet 122P/De Vico, with implications for understanding the origins of life.
Fluorescence spectroscopy can quickly and accurately discriminate between brain tumor and normal tissue, according to researchers at Cedars-Sinai Medical Center. The technique analyzes biochemical and functional changes in cells, providing high diagnostic specificity.
The new magnet features a uniform field of 21.1 Tesla in a volume 64 times larger than typical NMR systems, allowing for a wider range of scientific experiments. Scientists can now explore new avenues in chemical and biomedical science using this unique national resource.
Researchers have made significant progress in understanding how proteins interact with DNA. Using NMR spectroscopy, Rutgers chemist Babis Kalodimos determined how proteins find their specific sequences among millions of non-functional ones. This breakthrough offers valuable insights into protein-DNA interaction and gene expression.
Research using proton magnetic resonance spectroscopy found reduced cortical GABA levels and increased glutamate in melancholic depression patients, a subset of major depressive disorder. The study adds to evidence suggesting both GABA and glutamate systems contribute to mood disorders' pathophysiology.
During next week's transit, NCAR scientist Brown will examine regions of the solar spectrum absorbed by Venus's atmosphere between 65 and 85 kilometers altitude. He will also construct wind patterns based on gases' Doppler shifts to reveal atmospheric composition and temperature.
Researchers at Dartmouth College developed and tested three alternative breast imaging methods to learn about breast tissue structure and behavior. The non-invasive techniques include electrical impedance spectral imaging, microwave imaging spectroscopy, and near infrared spectral imaging.
Researchers at Dartmouth Medical School have developed a new breast imaging technique using electrical impedance, microwave imaging, and near-infrared spectroscopy. The method can identify specific breast characteristics that differ in normal and diseased tissue, potentially leading to early detection of breast cancer.
Researchers used MR spectroscopy to analyze 27 patients with previously treated brain tumors and found that Choline, Creatine, and N-acetylaspartate were detectable markers for tumor identification. Early detection can lead to timely treatment and prevent unnecessary therapy.
According to the study, MRI is superior to ultrasound in predicting cerebral palsy in preterm infants. Ultrasound should be used as the first imaging technique due to its availability and lower cost.
A new DNA test using Fourier transform-infrared spectroscopy has been developed to identify patients with myelodysplasia (MDS) or those at high risk of developing the disease. The test is highly predictive and can distinguish MDS patients from those with non-malignant bone marrow disorders.
A new imaging technique uses MRI and spectroscopy to analyze choline levels in tumors, accurately identifying malignant carcinomas in 8 out of 8 cases. The study suggests MRSI may aid physicians in diagnosing breast cancer and could potentially replace biopsy in certain cases.
Wilks pioneered commercial development of infrared absorption cells and ATR, advancing IR spectroscopy in industrial, academic, and research applications. He also contributed to gas chromatography-IR and developed portable gas analyzers for workplace monitoring.
Researchers studied how microbes control chemistry on mineral surfaces and found that bacteria produce surface coatings made of iron sulfate and goethite. The results show a fundamental difference between individual organisms and groups in controlling the process.
A new MRI technique using whole brain N-acetylaspartate (WBNAA) measures the amount of NAA in the brain, which decreases with MS disease progression. This method is more sensitive and specific than current markers, enabling earlier treatment monitoring and drug development for MS patients.
Researchers developed a magnetic resonance spectroscopy method to quantify choline levels in breast tissue, distinguishing malignant lesions from benign lumps. The technique uses high magnetic fields and mathematical approach to account for tissue variations.
Researchers created a nanoscale model catalyst that enhances hydrogen desulfurization efficiency by 100 times, enabling detailed analysis of the reaction at atomic levels.
Researchers at Purdue University have discovered a new method using infrared spectroscopy and statistical analysis to classify dietary supplement oils and common food oils. The study found that the FT-IR method could identify adulteration levels down to 2%, allowing for faster and less expensive quality control.
Studies found that patients with vascular dementia had less NAA in regions involved in short-term memory and language, while those with Alzheimer's had substantial NAA deficits. Accuracy improved when combining MRI and MR spectroscopy measures, suggesting potential for recovery through drug treatment.
Researchers at Purdue University have developed a new method to accurately measure quantities of a cheese-ripening enzyme in milk. The study combines infrared spectroscopy with statistical analysis to determine the concentration of plasminogen, enabling the creation of a model of the enzyme system function.
Researchers have developed the most effective commercially available black coating, NPL Super Black, with a low reflectance of 0.35% in the visible region. This breakthrough has significant implications for fields like radiometry, spectroscopy, and optical metrology, where stray light reduction is crucial.
A new technique developed by Malins' laboratory uses Fourier transform-infrared spectroscopy to analyze DNA from prostate tumor biopsies, allowing doctors to identify patients at high risk for metastasis. This breakthrough enables more informed treatment decisions and potentially saves lives.
Jacox, a leading expert on free radicals, has been recognized for her contributions to spectroscopy. Her work reveals the importance of free radicals in driving chemical reactions and understanding their role in various molecular processes.