Researchers found ustekinumab, used to treat psoriasis, also improves aortic inflammation, a key marker of cardiovascular risk. The drug resulted in a 19% improvement in aortic inflammation and significant reductions in skin inflammation.
Research reports cases of shingles developing at original vaccination site after chicken pox immunization, highlighting the importance of recognizing vaccine-associated shingles. The condition is rare but may correlate to the vaccination site.
Researchers found a significant link between acne and major depression, with a 63% higher risk within the first year of diagnosis. The study highlights the importance of monitoring mood symptoms in patients with acne and initiating prompt treatment for depression.
A study found that few dermatologists prescribe opioids, but those who do concentrate in Southern states and surgical practices. Higher rates of opioid prescribing were also observed among dermatologists in these areas.
Researchers combined tofacitinib, an arthritis medication, with narrow band ultraviolet B light therapy to restore skin color in patients with vitiligo. After a few months of treatment, both patients experienced near-total restoration of skin pigmentation.
The special section on OCT published by SPIE Journal of Biomedical Optics highlights its continued relevance in medicine and biology. New opportunities emerge in areas like gastroenterology, dermatology, and oncology.
A new clinical trial shows that using a generic skin cream containing fluorouracil (5-FU) for two to four weeks can reduce the risk of squamous cell carcinoma (SCC) needing surgery by 75% within a year. The study, led by Dr. Martin A. Weinstock, involved over 900 military veterans at high risk for keratinocyte carcinoma skin cancer.
Facial exercises improved middle-aged women's facial appearance by increasing muscle volume and reducing visible signs of aging. After 20 weeks, participants showed a significant decrease in age appearance, with average skin firmness and fuller upper and lower cheeks.
Researchers analyzed medical records of 487,104 black women and found that those with CCCA had a significantly higher prevalence of uterine fibroids compared to controls. The findings suggest a possible link between the two conditions, warranting increased awareness among physicians and patients.
Researchers from the University of Pennsylvania found that black, Asian, and other non-Hispanic minorities are about 40% less likely to see a dermatologist for psoriasis than whites. Whites averaged double the number of doctor's appointments for psoriasis overall compared to non-Hispanic racial minorities.
Scientists at King's College London have discovered a seaweed compound that can protect human skin from UV radiation without harming marine ecosystems. The mycosporine-like amino acid, palythine, has been shown to absorb harmful rays and offer antioxidant protection against cellular damage.
A research team from Columbia University has developed a molecular taxonomy for hair disorders, which will help diagnose diseases affecting the hair follicles. The taxonomy was created by analyzing more than three million data points and identified nearly 5,000 biological terms shared by groups of hair genes.
A study published in JAMA Dermatology found that high-quality photographs taken by parents with their smartphones can accurately diagnose pediatric skin conditions without an office visit. The results showed a 83% agreement between photograph-based and in-person diagnoses, paving the way for improved access to care through telemedicine.
Researchers found a strong connection between psoriasis severity and the risk of developing type 2 diabetes. Patients with more severe psoriasis are 64% more likely to develop diabetes than those without the condition.
Researchers found that supervised exercise accelerated ulcer healing time by 22 weeks compared to compression therapy alone. The study suggests benefits for patients with venous leg ulcers, including cost savings.
A new treatment reduced disease burden in patients with skin-predominant dermatomyositis, improving patient-reported quality of life and symptom assessments. The treatment, anabasum, was well-tolerated with mild side effects.
A new study analyzes Google Trends data across eight countries, finding summer and fall seasons correlate with greater hair loss. The findings provide evidence for seasonality in hair loss at a population level, supporting future research into the physiology of the hair cycle.
A new Cleveland Clinic study emphasizes the significance of prompt treatment in stage I melanoma, with patients treated within 30 days showing better survival rates. Delayed treatment beyond 90 days led to significantly worse outcomes, especially among older patients and those with comorbidities.
A new study found that delays in melanoma surgery are common among Medicaid and privately insured patients, highlighting the need for better access to specialty care. The likelihood of surgical delay decreased when dermatologists performed operations or made diagnoses.
A study found that Medicaid patients experienced surgical treatment delays more frequently than those with private insurance for melanoma surgeries. Non-white patients and those without dermatologist referrals also faced longer wait times.
A study led by NYU Langone Health found that removing a 2mm margin from suspicious moles can completely remove cancer cells with a single procedure. Researchers monitored patients for over a year and found no further suspicious growths, with 90% of biopsied moles being completely removed.
A new study from the University of Pennsylvania found that black children with eczema are 30% less likely to see a doctor for treatment compared to white children. Despite having more severe disease, minority children experience lower healthcare utilization rates due to various barriers.
A Northwestern Medicine study reveals that many 'fragrance-free' and 'hypoallergenic' moisturizers contain allergens, making it difficult for patients to find affordable and safe options. The study found that only 12% of the top-selling moisturizers were free of common skin allergens.
Researchers found patients with psoriasis covering 10% or more of their body surface area are at almost double the risk of death. The study used an objective measure of disease severity to analyze the relationship between psoriasis severity and mortality.
A national survey of pubic hair grooming habits found that 76.1% of participants reported a history of grooming, with 25.6% experiencing injuries such as cuts, burns, and rashes. The study's findings may contribute to the development of clinical guidelines for safe pubic hair removal.
Research suggests a connection between psoriasis and psychiatric illnesses, with inflammation being a key underlying factor. Psoriasis patients are at higher risk of anxiety, depression, and suicidal thoughts due to the debilitating nature of their condition.
A recent study published in JAMA Dermatology identified key features linked to amelanotic melanoma, including the absence of moles on the back, multiple freckles, and sun-sensitive traits. These characteristics may trigger doctors and patients to pay attention to pink spots that could be indicative of this type of skin cancer.
A new study found that sharing personalized melanoma genomic risk information with relatives and friends can lead to increased discussions about skin cancer prevention. The study suggests that this process could encourage healthy behavior change within families.
A recent analysis of published studies found that higher alcohol intake increases the risk of basal cell carcinoma by 7% and cutaneous squamous cell carcinoma by 11% for every 10 gram increase per day. The study suggests that limiting alcohol consumption may help reduce skin cancer risk.
A study published in Journal of the American Academy of Dermatology shows that MKTP surgery can restore skin pigmentation in vitiligo patients for up to five years. The procedure, which involves transplanting melanocyte cells, demonstrates long-term benefits with high repigmentation rates.
A new clinical trial found that high doses of vitamin D can reduce skin redness, swelling, and inflammation after a sunburn. Vitamin D at doses of 50,000-200,000 IU was shown to have long-lasting benefits in reducing skin inflammation and promoting skin barrier repair.
Emergency room visits for shingles increased among patients aged 20-59 years old after vaccination, while decreases were seen in younger and older groups. Shingles-related costs rose by 111% from 2006 to 2013, with the majority attributed to middle-aged patients.
A new study published in the British Journal of Dermatology found that adults with atopic dermatitis were not at increased risk for cardiovascular problems such as high blood pressure, Type 2 diabetes, heart attacks, or strokes. The research suggests that eczema is likely not positively associated with cardiovascular disease.
Three Penn researchers, Elizabeth Grice, Vijay Bhoj, and Kara Maxwell, have been awarded $1.9 million in Burroughs Wellcome Fund grants to investigate skin microbiome functions and CAR T-cell immunotherapy for Hemophilia A. The grants aim to advance our understanding of human infectious diseases and cancer research.
Researchers have developed a way to increase pigmentation in human skin without the damaging effects of ultraviolet (UV) radiation. A new class of small-molecule inhibitors has been found to activate the pigmentation pathway, inducing significant darkening similar to UV-induced tanning.
Researchers develop a class of small molecules that penetrate and darken human skin samples in the laboratory. The drug generates protective tans in red-haired mice, which are more susceptible to skin cancer via UV radiation.
A new analysis found that women pay an average of 40 percent more than men for minoxidil foams, a hair loss remedy known as Rogaine. Researchers compared prices at 24 different pharmacies across four states and found the cost difference despite similar ingredients.
Researchers have identified 16 new genetic markers associated with psoriasis, bringing the total to 63 loci linked to the disease. The largest psoriasis meta-analysis to date, involving over 39,000 participants, has shed light on pathways related to the disease and pinpointed potential gene targets.
Researchers at UT Southwestern Medical Center discovered that a protein called KROX20 is essential for hair pigmentation and a gene called SCF determines the color of hair. The study found that deleting these genes leads to gray or white hair in mice, providing potential insights into balding and aging.
Scientists at Lund University have identified a novel defence mechanism that uses thrombin fragments to aggregate and neutralize bacteria and toxins in wounds. This discovery could provide an alternative approach to treating bacterial infections, potentially reducing the reliance on antibiotics.
A study by Brigham and Women's Hospital found that Medicare spending on topical steroids increased by 226.5% and out-of-pocket costs for patients rose by 145.9% between 2011 and 2015. Researchers suggest using physician decision support to pick more affordable generic options, potentially saving $944.8 million and $66.6 million.
Researchers at CU Anschutz Medical Campus found that cannabinoids may be effective in treating eczema, psoriasis, and other skin diseases. Topical cannabinoid drugs with little psychotropic effect could provide relief for patients with itchy skin conditions.
Researchers at the University of Missouri have developed a new technique, sonoillumination, which uses ultrasonic pulsation to improve laser transmission through skin tissues. This technique has the potential to reduce safety concerns in laser dermatology and provide safer, more effective treatment options for patients.
Researchers identify genes involved in lipid uptake as critical for TRM cell function, revealing a key dependency on fatty acids. Targeting these lipids could enable selective removal of TRM cells, offering new therapeutic opportunities for autoimmune diseases.
A study from Drexel University found that nonwhite organ transplant recipients require unique dermatological care due to varying skin cancer risk factors and locations. The research highlights the importance of evaluating and treating patients differently based on their race, with a focus on sun-protected areas and high-risk human papi...
Two CDC studies examine indoor tanning and sun safety trends among US high school students. Indoor tanning rates dropped from 15.6% to 7.3% between 2009 and 2015, but sunburns remained common. Sun safety practices are also scarce in schools, with only 47.6% of schools implementing sunscreen application during class time.
A new article published online by JAMA Dermatology estimates the global burden of skin disease, with dermatitis and acne vulgaris ranking among top causes. Skin diseases accounted for 1.79% of the global burden of disease in 2013, equivalent to 41.6 million DALYS.
A study published in JAMA Dermatology found that actinic keratosis management costs differ significantly across regions. The researchers discovered that understanding these geographic variations can help identify areas with excessive spending and potential for cost savings.
A study published in JAMA Dermatology ranks the top 10 most disabling skin diseases globally, with dermatitis and acne at the top. The research also highlights the disproportionate impact of non-cancer skin conditions on global health.
A new study found that psoriasis patients who developed depression were 37% more likely to develop psoriatic arthritis compared to those without depression. This highlights the need for early detection and prevention of depression in psoriasis patients.
A new paper outlines expressions of skin conditions often misdiagnosed as brown recluse bites, including bacterial infections and deadly reactions. The authors introduce the NOT RECLUSE mnemonic device to help doctors accurately diagnose these cases.
A study published in JAMA Dermatology found that neither a beach umbrella nor SPF 100 sunscreen alone prevented sunburn completely, with 78% of those under an umbrella and 25% of those using sunscreen developing sunburn. The study highlighted the importance of combining sun protection practices for optimal protection against UV rays.
A new study published in JAMA Dermatology found that non-heterosexual black male teens engage in indoor tanning at levels equal to those of heterosexual white females. This discovery highlights a surprising new group at risk for skin cancer, which may be linked to psychological distress and discrimination.
Researchers at the University of Pennsylvania School of Medicine have made a groundbreaking discovery in wound healing by transforming myofibroblasts into fat cells. This innovation has the potential to revolutionize dermatology and develop new treatments for conditions such as HIV-related complications and aging skin.
A large international survey found imperfections in primary and secondary prevention of skin cancer, with regional differences in sun protection behaviors. The study's results suggest that education level, gender, and socioeconomic status influence sun protection habits.
A review of dermatology clinical trials found that racial and ethnic groups are underrepresented among study participants, with most being white. The lack of diversity is attributed to inadequate reporting of ethnicity and race, which may lead to a more homogenous population. To address this issue, the review suggests prioritizing raci...
According to the study, 11 of the 49 states with reported melanoma incidence rates saw a decrease, while 38 states experienced an increase. The researchers suggest that better treatment may be prolonging the life of patients with melanoma.
A new study reports an estimated 76,380 Americans will be diagnosed with melanoma in 2016, with current lifetime risk being 1 in 54 for invasive melanoma. The overall burden of disease is increasing, with rising rates and higher mortality rates, exceeding the previous estimate of 10,130 deaths
Women are more susceptible to autoimmune diseases due to a new regulatory mechanism identified by researchers. The study found that the master regulator gene VGLL3 promotes autoimmunity in women, regardless of sex hormone involvement.
A Northwestern Medicine study shows that trained partners can catch far more mole irregularities than control group participants, growing their confidence and trust along the way. Common areas prone to developing fatal melanoma include hard-to-see spots on the body.