The Block ICTR provides a comprehensive framework for translating biomedical discoveries into new treatments, with resources for community engagement, biostatistics, and clinical trials. Einstein and Montefiore will leverage their unique strengths to support innovative research programs across multiple disease areas.
Researchers at UCSF have discovered a new way to target cancer by controlling cell growth and boosting protein production during the S phase of the cell cycle. This study has implications for the development of new cancer therapies.
A recent study found no significant increase in serious diseases among HPV-vaccinated girls compared to unvaccinated peers, despite monitoring over 900,000 participants. The researchers also noted that mild adverse reactions such as fever and swelling are common but not considered a concern.
A new study from Harvard School of Public Health finds that living close to an airport increases the risk of cardiovascular hospital admissions among older adults. The researchers analyzed data from 6 million participants and found that aircraft noise was associated with a 3.5% higher hospital admission rate for cardiovascular disease.
Children with high blood pressure readings are three times more likely to develop the condition as adults. The study highlights the need for pediatricians to regularly check blood pressure and weight in children.
The landmark study discovered four novel gene variations linked to blood pressure in African-Americans, which also show associations across other populations. Genetic factors account for 40-50% of individuals' susceptibility to hypertension.
The National Cancer Institute has renewed a five-year, $11.3 million grant to support research on thyroid cancer at The Ohio State University Comprehensive Cancer Center. The study focuses on four integrated projects to better understand genetic pathways and signaling in epithelial thyroid cancer.
A team of researchers from UCSF analyzed medical records and found that most thyroid nodules are benign, not malignant cancers. They suggest biopsying only patients with microcalcifications or large solid nodules over two centimeters in diameter to reduce unnecessary procedures.
A new bioinformatics software tool, DrGaP, has been developed to identify genetic mutations responsible for cancers. The tool combines statistical methods and bioinformatics tools to distinguish between driver mutations and passenger mutations, leading to a more complete identification of altered genes and signaling pathways in cancer.
The GEMINI studies found vedolizumab to be an effective treatment for patients with moderately to severely active Crohn's disease and ulcerative colitis. The study suggests that the drug may provide people living with these conditions an additional option for inducing and maintaining clinical remission.
Researchers at UCSF recommend six measures to prevent hepatitis C, including clean syringe programs, social issue addressing, and injection cessation interventions. The study estimates 31,000 new cases per year among young injectors in the US.
Research finds bystanders intervene in about a third of bar fights, with most intervening in male-male conflicts. Nonviolent interventions were used in 65% of male-male fight breakups, while incidents between males and females received the lowest intervention rates.
Researchers developed statistical models to predict which drug is best for a specific individual with a specific disease, considering pharmacokinetics, pharmacodynamics, and genetic factors. The framework will help doctors and pharmacists simulate variables like protein-protein interactions and predict treatment effectiveness.
A new conversation guide aims to improve physicians' ability to discuss end-of-life care with patients, addressing the growing need for sensitive discussions due to an aging population and chronic illness. The guide provides practical advice on identifying high-risk patients, communicating prognosis, and clarifying patient values.
A new 'conversation guide' aims to increase physicians' confidence in engaging patients in meaningful end-of-life discussions. The framework provides structured guidance on identifying high-risk patients, communicating prognosis, and involving substitute decision-makers.
A new study conducted by Indiana University found that postmenopausal women who quit smoking reduced their risk of heart disease, with benefits starting to show within years. The study analyzed data from 104,391 women ages 50-79 and found a significant drop in heart disease risk among those who quit smoking, regardless of diabetes status.
A University of Iowa study reveals significant disparities between minority and white clients in completing substance abuse treatment programs. Successful completion predicts greater likelihood of getting off drugs, abstinence from alcohol, and employment six and 12 months after treatment completion.
A UC San Francisco-led study found that men with non-metastatic prostate cancer who consumed more healthy vegetable fats had a lower risk of developing lethal prostate cancer and dying from other causes. Replacing 10% of daily calories with these fats was associated with a 29% lower risk of lethal prostate cancer.
A US study found that reducing unnecessary and high-dose pediatric CT scans could lower the overall lifetime risk of future imaging-related cancers by 62 percent. The research suggests that eliminating unnecessary imaging and lowering doses for the highest-dose scans could prevent thousands of future cancers.
A new study found that CT scan use increased by 15 years in children at nonprofit health care delivery systems, exposing them to higher cancer risk. Strategies like Image Gently aim to reduce this risk by lowering radiation doses and eliminating unnecessary scans.
Policies allowing medical school faculty to care for family while advancing their careers are more available than ever, yet underutilized. A comprehensive communications intervention at UC Davis increased awareness and reduced barriers to use, promoting a culture shift in support of family-friendly policies.
The new journal aims to cover all areas of research in human proteomics, using multi-disciplinary approaches to untangle complex disease processes. It will provide a platform for high-quality, multi-disciplinary studies combining early discovery with clinical applications.
Researchers at UC San Francisco found that giving small amounts of formula to infants experiencing high early weight loss can increase the length of time their mothers end up breastfeeding. This study provides evidence for the benefits of 'early limited formula' in some newborns.
Researchers at Penn Medicine have identified four new genetic variants associated with an increased risk of testicular cancer, with markers found at four loci, including 4q22, 7q22, 16q22.3, and 17q22.
A new genomic test helps identify low-risk men suitable for active surveillance, sparing them from unnecessary treatment. The test provides statistically significant and clinically meaningful prognostic information, aiding in determining which men are best suited for active surveillance.
Two studies presented at EuroPRevent 2013 found that physically demanding work increases the risk of coronary heart disease. The research suggests that job strain and high physical demands may exacerbate cardiovascular risks, even when leisure-time activity is taken into account.
A new study found that each additional hour of sleep is associated with a lower BMI for teens. Increasing sleep duration to 10 hours per day could help reduce the prevalence of adolescent obesity. The findings suggest delaying school start times could also aid in reducing obesity rates.
New research found that U.S. adolescents with poor health behaviors and unfavorable cardiovascular risk factors are at increased risk of developing heart disease in adulthood. The study analyzed data from over 4,700 adolescents aged 12-19 and found that nearly 80% had a poor diet, while less than 50% met the recommended levels for phys...
A new University of Iowa study suggests that deployment of a parent puts children at an increased risk for drinking alcohol and using drugs. The study found a three-to-four-fold increase in binge drinking among children of deployed or recently returned military parents compared to non-military families.
A new study by Michigan State University found that about four percent of HIV-positive individuals also have hepatitis, highlighting the need for stronger protections against co-infection. The study reveals that behaviors putting people at risk of HIV also increase their risk of getting hepatitis B or C.
A Swedish study found that females with university-educated parents were 15 times more likely to receive an HPV vaccine before age 20. The researchers also noted a decrease in genital warts incidence among unvaccinated women over 20 years old, suggesting a self-selection bias where high-risk women preferentially sought vaccination.
A new study by Michigan State University found that young people with epilepsy experienced significant reductions in stigmatization after participating in regular peer support groups. The research, published in Epilepsy and Behavior, suggests a potential solution to the debilitating stigma surrounding epilepsy in developing countries.
A large epidemiological study found that short-term exposure to outdoor heat increases the risk of hospitalization for COPD and respiratory tract infections in the elderly. The risk was consistent across all age groups and genders, with a strong association between heat and hospitalizations.
A comprehensive study has identified seven new regions of the human genome associated with increased risk of age-related macular degeneration (AMD). The study, led by Case Western Reserve University School of Medicine, found that AMD is not caused by a single genetic change but rather by many events that accumulate over time.
Researchers analyze air pollution levels and health effects, identifying communities at higher risk for respiratory diseases. The study aims to improve understanding of cause-and-effect relationships between pollution and health outcomes.
Research found that a high intake of Southern-style foods, including fried chicken, bacon, and sugary drinks, was associated with a higher risk of stroke. In contrast, those who ate more fruits, vegetables, and whole grains had a lower risk of stroke.
Researchers at UMass Amherst have developed a new method called MixMAP that uses existing public databases to reveal substantial new information about genes associated with high cholesterol and heart disease. The approach provides opportunities for developing new treatments and identifying people at greatest risk.
A UCSF study of over 140,000 women aged 66-89 found that biennial screening led to fewer false positives and no increased risk of late-stage breast cancer. The study suggests life expectancy and co-existing illnesses should be considered when making cancer screening recommendations for older women.
A UK study found that improved prevention measures failed to reduce HIV levels among men who have sex with men in England and Wales, despite increased testing and treatment rates. The researchers suggest that targeting the most-at-risk groups and initiating treatment earlier may be necessary to bring about a drop in HIV incidence.
Researchers at Weill Cornell Medical College found that less than half of black patients with uncontrolled hypertension were prescribed a diuretic drug, despite its proven benefits and low cost. The study highlights the need for physicians to follow established guidelines and prescribe diuretics as recommended for this population.
A comprehensive study analyzed 232 papers on prostate cancer treatments and found that surgery is the most cost-effective option, saving lives at a lower cost than radiation therapy. The analysis also showed that treatment plans for localized prostate cancer vary dramatically across different centers.
The conference, organized by IRB Barcelona and the BBVA Foundation, brings together experts to discuss the virtues of statistics for biomedical applications and present current state of the discipline. Biostatistics is applied to clinical assays, scrutinizing huge amounts of data and integrating information from diverse sources.
A nationwide survey of obstetricians and gynecologists found that many doctors perform routine pelvic exams in low-risk women due to misconceptions about ovarian cancer screening. The study suggests that the exams may be performed for non-clinical reasons, such as reassurance or expectation, rather than medical necessity.
A collaborative research effort has pinpointed the genetic footprint that links fragile X syndrome and autism. The findings identify at least 93 genes controlled by the fragile X mental retardation protein, which are also linked to other neurologic syndromes.
A new method of prenatal testing using microarray technology is providing physicians with more comprehensive results than conventional karyotyping, according to George Washington University researchers. The study found that microarray analysis can identify additional abnormalities not detectable by karyotyping, allowing for earlier int...
Researchers will study how maternal parasite infections affect fetal immune systems to identify effective interventions promoting healthy growth in children. The goal is to understand the causes of stunted growth and develop affordable solutions.
A new study published in Genetics reveals that assessing skin cancer risk can be improved by accounting for genetic factors, such as family history and ethnicity. The researchers developed a more precise model for assessing risk using phenotypic and genetic information from over 5,000 participants.
A new study found an association between reduced fine particulate matter and increased life expectancy in US counties from 2000 to 2007. Reducing air pollution levels may be more beneficial for women, with a stronger link in urban areas.
A recent study of over 25,000 individuals with ADHD found that criminal behavior dropped sharply during periods of medication use. The study showed a significant 32% risk reduction for medicated individuals compared to those not taking medication.
Researchers at McMaster University discovered a novel molecular basis for depression, finding the FTO gene is associated with an eight per cent reduction in the risk of depression. The study found no link between obesity and depression, contradicting common perception that obese individuals are more likely to be depressed.
Recent studies claiming to use brain scans for autism diagnosis are flawed and unreliable. Researchers need to conduct large-scale multicenter studies to understand the biological basis of autism.
A new study shows that New Jersey's decal law for novice drivers has prevented over 1,600 crashes and helped enforce regulations. The law, which requires a red decal on license plates, led to a 9% decrease in crashes involving peer passengers.
A UNM Cancer Center researcher is investigating the link between mitochondrial DNA and ovarian cancer. She hopes to identify genetic markers that could lead to a screening test or therapy, potentially increasing survival rates.
Researchers found that people in creative professions are treated more often for mental illness than the general population, particularly for schizophrenia. Creative fields were also associated with higher rates of bipolar disorder, depression, anxiety syndrome, substance abuse, and suicidal behavior.
A comparative analysis of elderly individuals found that benzodiazepine use was associated with a 50% increased risk of developing dementia. The study recommends limiting prescriptions to periods of a few weeks and ensuring proper use to mitigate potential adverse effects.
A 5-year, $134 million grant from the National Institute of Health will support a clinical trial examining four glucose-lowering medications for type 2 diabetes treatment. The study aims to determine which therapy most effectively and safely reaches and maintains near normal levels of blood glucose.
The Canadian Longitudinal Study on Aging (CLSA) is a comprehensive study on aging that will investigate factors affecting health and quality of life in Canadians. The Montreal component, launched by the Research Institute of McGill University Health Centre, will collect data from 3,000 people between ages 45-85 for a 20-year period.
A recent study identified a gene linking age-related cataracts and Alzheimer's disease, suggesting common etiologic factors between the two conditions. The study found correlations between cortical cataract formation and brain degeneration measures, as well as poorer cognitive performance.
The university has received nearly $24.5 million in grants, including almost $14 million for the Epidemiology of Diabetes Interventions and its Complications study. The funding will help researchers investigate the long-term effects of glycemia on diabetes complications and improve healthcare quality in targeted communities.
A new study has identified a gene that appears to make women happy, but not men. The low-expression form of the MAOA gene is associated with higher self-reported happiness in women.