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Barcelona Institute for Global Health (ISGlobal)


Reducing traffic in Barcelona by 25% would prevent around 200 premature deaths a year linked to pollution

A study by Barcelona Institute for Global Health estimates that reducing motorized traffic in the city would lead to a 17.6% reduction in nitrogen dioxide levels and prevent nearly 200 premature deaths annually. The addition of port electrification could further increase avoidable deaths to 228 per year.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalHealth & Place·TypeCase study·DateMar 25, 2025

Symptoms of long-COVID can last up to two years after infection with COVID-19

A study of the COVICAT cohort found that almost one in four people infected with SARS-CoV-2 developed long COVID, with symptoms persisting for two years or more. Risk factors included severe COVID-19 infection and pre-existing chronic diseases, while vaccination before infection and a healthy lifestyle appeared to reduce the risk.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalBMC Medicine·TypeObservational study·DateMar 13, 2025

High temperatures could affect brain function in preadolescents

A study of over 2,200 children found that high ambient temperatures are associated with lower connectivity in key brain networks, potentially impacting processes such as attention and memory. The association was strongest on the day before a brain scan and decreased on subsequent days.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalJournal of the American Academy of Child & Adolescent Psychiatry·TypeImaging analysis·DateMar 6, 2025

Improving the distribution of green spaces in Barcelona could prevent 178 premature deaths each year

A study by Barcelona Institute for Global Health estimates that increasing green spaces in the city could prevent 178 premature deaths per year. The proposed Green Corridors plan would lead to a 3.64% increase in green space, reducing mortality rates and heat-related deaths.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalEnvironment International·TypeComputational simulation/modeling·DateFeb 24, 2025

Landmark study of Chagas disease in Paraguay supports use of rapid tests to improve access to diagnosis

A landmark study led by ISGlobal found that combining rapid diagnostic tests with conventional serology improves access to diagnosis for Chagas disease. The prevalence of Chagas is six times higher in an indigenous community in Paraguay compared to the capital.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalPLOS Neglected Tropical Diseases·TypeObservational study·DateFeb 18, 2025

Exposure to air pollution associated with more hospital admissions for lower respiratory infections

Research found that long-term exposure to air pollutants like PM2.5, NO2, and ozone increases hospital admissions for lower respiratory tract infections in adults, particularly among men and people over 65. The study used a large cohort of adults from Catalonia and found stronger associations in these vulnerable groups.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalEnvironment International·TypeData/statistical analysis·DateFeb 3, 2025

New insights into the biology and risk factors of childhood obesity

A cutting-edge molecular approach identifies three distinct clusters of children with metabolic complications, highlighting the importance of prenatal environment and exposure to industrial chemicals. The study provides a better understanding of biological pathways involved in metabolic health, beyond traditional clinical markers.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalNature Communications·TypeObservational study·DateJan 15, 2025

New tablet shows promise for the control and elimination of intestinal worms

A new tablet combining albendazole and ivermectin is safe and more effective than albendazole alone in treating Trichuris trichiura and other soil-transmitted helminths. The ALIVE clinical trial showed higher cure rates for T. trichiura, hookworms, and improved egg reduction rates compared to albendazole alone.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalThe Lancet Infectious Diseases·TypeRandomized controlled/clinical trial·DateJan 10, 2025

One of the world’s largest social programs greatly reduced tuberculosis among the most vulnerable

A landmark study by Barcelona Institute for Global Health found that Brazil's Bolsa Família Program reduced TB cases and deaths among extreme poverty, indigenous groups, and improved healthcare access. The program's effects were stronger among the poorest and indigenous populations, with a 50-60% decrease in TB cases.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalNature Medicine·TypeData/statistical analysis·DateJan 3, 2025

More than half of European heat-related deaths in summer 2022 attributed to anthropogenic warming

A new study by the Barcelona Institute for Global Health found that more than half of European heat-related deaths in summer 2022 were related to human-induced climate change. The research showed a higher number of heat-related deaths attributed to climate change among women and people aged 80 and over.

SourceBarcelona Institute for Global Health (ISGlobal)·Journalnpj Climate and Atmospheric Science·TypeData/statistical analysis·DateOct 29, 2024

Maternal antibodies interfere with malaria vaccine responses

Research led by ISGlobal reveals that children younger than five months of age may benefit from the RTS,S and R21 malaria vaccines if they live in areas with low malaria transmission, where mothers have less antibodies to the parasite. The study analyzed blood samples from over 600 children and infants and found that high levels of mat...

SourceBarcelona Institute for Global Health (ISGlobal)·JournalThe Lancet Infectious Diseases·TypeRandomized controlled/clinical trial·DateOct 23, 2024

Keeping a longer overnight fast and eating an early breakfast may be associated with a lower body mass index

A recent study published in the International Journal of Behavioral Nutrition and Physical Activity suggests that extending overnight fasts and eating an early breakfast may be associated with a lower body mass index. The research, led by the Barcelona Institute for Global Health, involved over 7,000 volunteers who answered questionnai...

SourceBarcelona Institute for Global Health (ISGlobal)·JournalInternational Journal of Behavioral Nutrition and Physical Activity·TypeObservational study·DateSep 30, 2024

Microorganisms can travel long distances in the troposphere

A recent study by ISGlobal found a vast range of viable bacteria and fungi transported by air masses from northeast China to Japan, some potentially pathogenic to humans. The research team identified over 266 fungal and 305 bacterial genera in aerosol samples, including species resistant to commonly used antibiotics.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalProceedings of the National Academy of Sciences·TypeObservational study·DateSep 11, 2024

Neurological symptoms are common - and similar- in severely ill children with different conditions

A new study by ISGlobal reveals that nearly half of children with severe illnesses in low- and middle-income countries exhibit neurological symptoms before death. The most common causes of death were lack of oxygen, meningitis, and cerebral malaria. However, lumbar punctures are seldom performed, making diagnosis challenging.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalJAMA Network Open·TypeObservational study·DateSep 4, 2024

Heat caused over 47,000 deaths in Europe in 2023, the second highest burden of the last decade

A study led by ISGlobal estimates that heat caused over 47,000 deaths in Europe in 2023, with southern European countries being the most affected. The mortality rate was higher in women and people over 80 years old, and without societal adaptation processes, it would have been 80% higher.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalNature Medicine·TypeData/statistical analysis·DateAug 12, 2024

Children living in greener neighborhoods show better lung function

A meta-analysis of 35,000 children from eight European countries has found a robust link between exposure to green spaces and better lung function. Children living in greener neighborhoods had higher forced vital capacity (FVC) and forced expiratory volume in one second (FEV1), indicating improved airway function.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalEnvironment International·TypeMeta-analysis·DateJul 17, 2024

Compact cities have lower carbon emissions, but poorer air quality, less green space and higher mortality rates

A study by ISGlobal analyzed 919 European cities, identifying four urban configurations: compact-high density, open lowrise-medium density, open lowrise-low density, and green-low density. Compact high-density cities have lower carbon footprints but higher mortality rates due to poorer air quality and less green space.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalThe Lancet Planetary Health·TypeData/statistical analysis·DateJul 3, 2024

An innovative test to diagnose chagas disease in newborns

A novel diagnostic test combining LAMP molecular amplification with a 3D printer-based DNA extraction system shows comparable sensitivity to PCR, offering a simple and rapid solution for detecting T. cruzi infection in newborns. Early detection is crucial for effective treatment, which was successfully applied in the study.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalThe Lancet Microbe·TypeExperimental study·DateJul 3, 2024

Prenatal exposure to ethylene oxide associated with lower birth weight and head circumference in newborns

A study of 1,106 newborns from five countries found that prenatal exposure to ethylene oxide is associated with lower birth weight and smaller head circumference. The results suggest that reducing exposure to ethylene oxide could protect fetal health and improve birth outcomes.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalEpidemiology·TypeObservational study·DateJun 27, 2024

A study led by ISGlobal and IDIAPJGol recommends strengthening immunity against COVID-19 in people with cancer

Researchers analyzed data from over 184,000 cancer patients to assess COVID-19 vaccine effectiveness. The study found that vaccination significantly reduces mortality and serious complications among cancer patients, especially those who received the booster dose.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalNature Communications·TypeObservational study·DateJun 19, 2024

Exposure to heat and cold in early life may affect development of white matter in the brain

A study of over 2,000 preadolescents found that early life exposure to extreme temperatures can lead to slower white matter maturation, which may impact cognitive function. Children living in poorer neighborhoods are more vulnerable to the effects of cold and heat, with differences in windows of susceptibility observed.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalNature Climate Change·TypeImaging analysis·DateJun 12, 2024

Exposure to mixtures of endocrine-disrupting chemicals during pregnancy is associated with higher odds of metabolic syndrome in children

A new study found that prenatal exposure to a combination of endocrine-disrupting chemicals is associated with poorer metabolic health in childhood, increasing the risk of metabolic syndrome in adulthood. Mixtures of metals, PFAS, and organochlorine pesticides were linked to higher risks.

A significant portion of the world’s population continues to trust vaccines, says survey in 23 countries

A survey across 23 countries found that the global population's overall trust in vaccination did not diminish despite COVID-19 pandemic challenges. More than 60% of participants reported increased willingness to get vaccinated for diseases other than COVID-19, suggesting a general openness to vaccination. The study emphasizes the impor...

SourceBarcelona Institute for Global Health (ISGlobal)·JournalNature Medicine·TypeData/statistical analysis·DateApr 30, 2024

Exposure to air pollution during the first two years of life is associated with worse attention capacity in children

A study published in Environment International found that exposure to nitrogen dioxide (NO2) during the first two years of life is associated with poorer attentional function in children aged 4-8, particularly in boys. The association persists even after adjusting for other factors.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalEnvironment International·TypeData/statistical analysis·DateApr 17, 2024

Effective malaria prevention in pregnant women despite drug resistance

A study in southern Mozambique found that sulfadoxine-pyrimethamine (SP) remains effective for preventing malaria infections in pregnant women, even in areas with high drug resistance. The study showed increased clearance of P. falciparum infections and lower antibodies resulting from parasite colonisation.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalJournal of Infection·TypeObservational study·DateApr 17, 2024

Study shows key role of physical activity and body mass in lung function growth in childhood

A new study published in Thorax reveals that increased physical activity and higher body mass index can help recover early-life lung function deficits, leading to normal values in adolescence. The study analyzed data from over 1,100 children and adolescents aged 4-18 years, identifying four trajectories of lung function growth.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalThorax·TypeObservational study·DateApr 15, 2024

Stressful events in midlife might be a risk factor for Alzheimer's disease in older ages

A recent study published in Annals of Neurology suggests that midlife stressful events may be a risk factor for developing Alzheimer's disease in older ages. Researchers found associations between stress and higher levels of beta-amyloid protein, neuroinflammation, and brain atrophy, particularly in men.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalAnnals of Neurology·TypeObservational study·DateApr 2, 2024

Air quality in Europe shows significant improvements over the last two decades, study finds

A study reveals significant improvements in European air quality over the last two decades, with declining levels of PM10 and NO2. However, 98.10% of the population lives in areas exceeding WHO recommended levels for PM2.5, leading to 86.34% experiencing unclean air days annually.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalNature Communications·TypeData/statistical analysis·DateMar 13, 2024

People deprived of liberty are at very high risk of tuberculosis, even years after release

A study in Paraguay found that people deprived of liberty are at a high risk of tuberculosis (TB) during and after incarceration. The risk persists for years after release, with the incidence of TB declining but remaining 10 times higher than in the community.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalThe Lancet Regional Health - Americas·TypeData/statistical analysis·DateJan 15, 2024

African women living with HIV have an effective option to prevent malaria during pregnancy

The MAMAH trial found that preventive treatment with DHA-PPQ significantly reduces the risk of malaria infection and disease in pregnant women living with HIV. Women in the treatment group had almost eight times lower risk of clinical malaria and half the risk of becoming infected compared to the placebo group.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalThe Lancet Infectious Diseases·TypeRandomized controlled/clinical trial·DateJan 12, 2024

Air conditioning has reduced mortality due to high temperatures in Spain by one third

A study published in Environment International found that air conditioning reduced heat-related mortality in Spain by up to 31.5%, while heating systems contributed to a decrease of 50.8% in extreme cold-related fatalities. However, the effect may be attenuated by an ageing population.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalEnvironment International·TypeData/statistical analysis·DateDec 18, 2023

Drug-resistant tuberculosis may be under-diagnosed, says genomic analysis in southern Mozambique

A genomic analysis in southern Mozambique found that new molecular tests are needed to detect a wider range of mutations conferring resistance to first-line TB drugs. The study identified high numbers of isoniazid-resistant cases, which were also missed by the Xpert/Ultra test.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalClinical Infectious Diseases·TypeData/statistical analysis·DateDec 4, 2023

High temperatures may have caused over 70,000 excess deaths in Europe in 2022

A new study developed a theoretical framework to re-evaluate the impact of record summer temperatures on European mortality. Using daily temperature and mortality records from 147 regions, researchers found that weekly, 2-weekly, and monthly models underestimated heat-related mortality, with errors increasing with aggregation period.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalThe Lancet Regional Health - Europe·TypeData/statistical analysis·DateNov 21, 2023

Social assistance programs are an effective strategy to mitigate the impact of economic crises on child health

A study in Brazil found that social pensions and conditional cash transfers significantly reduced child mortality rates between 13-16%. The impact was greater in poorer communities. Expanding these programs could avert nearly 150,000 child deaths by 2030.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalThe Lancet Regional Health - Americas·TypeData/statistical analysis·DateNov 16, 2023

Multinational study confirms association between CT scans in young people and increased risk of cancer

A multinational study of almost one million individuals found a strong association between exposure to radiation from CT scans in young people and an increased risk of blood cancers. The study confirms that the benefits of computed tomography outweigh the risks, but emphasizes the need for strict radiological protection measures, parti...

SourceBarcelona Institute for Global Health (ISGlobal)·JournalNature Medicine·TypeData/statistical analysis·DateNov 9, 2023