Researchers developed an advanced single-cell sorting platform that dramatically shortens the screening process for identifying high-value microbial strains. The technology enabled the isolation of a mutant strain producing 58% more DHA than the wild type in just two days.
Chinese researchers developed a groundbreaking 3D genome mapping technology that reveals how the 3D organization of plant genomes influences gene expression, especially in photosynthesis. The innovation provides a precise tool for understanding long-range chromatin interactions and their role in regulating biological processes.
The Late Ordovician Mass Extinction was caused by the rapid onset of global warming after the Hirnantian glaciation. The extinction lasted approximately 400 kyr with an average species extinction rate of 71.6% per 100 kyr during this period.
A study of ancient genomes from Yunnan, China, has provided new insights into human prehistory in East Asia. The research found that the region is pivotal to understanding the origin of both Tibetan and Austroasiatic population groups, with a previously unobserved Asian ancestry denoted as Xingyi ancestry.
A new study reveals that DNA methylation mediates the transgenerational inheritance of acquired cold tolerance in rice, supporting Lamarck's theory. Researchers developed a novel breeding strategy to develop stress-resilient crops, offering a promising avenue to tackle agricultural challenges posed by global climate change.
A new study reveals that deeply subducted carbonates can cause significant variations in Earth's mantle redox states, influencing diamond formation and craton evolution. This process shapes continent and diamond characteristics, with different mantle environments producing distinct redox signatures.
A new study of diffuse dwarf galaxies has revealed an exceptionally strong clustering pattern, contradicting the established understanding of galaxy clustering. The researchers propose a new model of dark matter based on the Self-Interacting Dark Matter (SIDM) theory.
Researchers find over 500 dense star-forming cores with possible protoplanetary disks in the Milky Way's Central Molecular Zone. Dual-band observations reveal unexpected spectral reddening, suggesting the presence of these early stages of solar system formation.
The study reveals the structure and activation mechanism of the human EP1 receptor, a key player in pain, cardiovascular disease, and certain cancers. The researchers identified unique residues that form a distinct binding motif for prostaglandin E2 and uncovered subtype-specific activation mechanisms.
The study elucidates the molecular mechanism of AUX1/LAX protein family-mediated auxin transport, highlighting the role of His249 residues in substrate recognition. This breakthrough sheds light on plant growth and development processes.
A joint Chinese-American research team has discovered the smallest known Archaeopteryx specimen, acquired by the Field Museum in 2022. The study provides crucial insights into the evolution of the skull and adaptations for flight during the transition from non-avian dinosaurs to birds.
The study provides crucial insights into the evolution of the skull and adaptations for flight in the critical transition from non-avian dinosaurs to birds. The Chicago Archaeopteryx specimen reveals an almost completely preserved skull with a palatal region intermediate between troodontids and more derived Cretaceous birds.
A team of Chinese researchers discovered that the body uses a unique fat molecule called ceramide-1-phosphate (Cer1P) to selectively recognize and manage specific bacteria in the gut. This 'dialogue' helps maintain intestinal health by triggering beneficial immune responses.
A recent study explores how ancient climate behavior can inform our understanding of the South Asian Summer Monsoon's (SASM) dynamics under climate warming. The study identifies similar SASM changes across past warm intervals, suggesting that insights from past warm climates can help predict future changes in monsoon circulation and ra...
A study of oyster fossils from the Early Cretaceous period reveals significant seasonal temperature fluctuations and periodic glacial melt events, overturning the traditional view of greenhouse climates. The findings suggest that elevated greenhouse gas concentrations may amplify seasonal extremes rather than lead to uniform warming.
A study published in Nature Neuroscience has uncovered the neural mechanisms by which social rank influences vulnerability to drug addiction. The research found that low-ranking mice exhibit a stronger reward circuit and weaker control circuit, making them more likely to seek drugs.
Chinese researchers have identified an insect predator using tools to exploit the collective defenses of social insects. The assassin bug, Pahabengkakia piliceps, weaponizes resin from stingless bee nests to lure bees into its optimal hunting position.
The USTC team identified a novel material design that enables record-breaking device performance in pure-red PeLEDs. They introduced a 3D intragrain heterostructure to enhance carrier confinement capacity, suppressing hole leakage and achieving unprecedented efficiency and brightness.
Researchers uncover pivotal role of cyclic dinucleotides in triggering bacterial immune response, leading to rapid and robust activation of defenses. The study provides a unified model for how CDNs trigger membrane-targeting immune responses across diverse immune systems.
Researchers achieve plastic warm metalworking in previously brittle semiconductors, enabling efficient and cost-effective manufacturing of high-performance electronic devices. The new technique unlocks new opportunities for scalable fabrication of thermoelectric devices with improved performance.
A recent study analyzed body size evolution in trilobites, a highly representative group of fossil invertebrates, and found that marine oxygen levels significantly influenced their body size. The research highlights the long-term impact of oxygen on the evolution of early metazoans.
A recent study reveals that a specific genetic variation affects the adherence of an anaerobic bacterium to tumor cells, promoting colorectal cancer progression. The study highlights the complex dynamics between host genetics and intratumoral microbiota in CRC progression.
A research team has uncovered a reciprocal regulatory relationship between extrachromosomal DNA maintenance and the DNA damage response in tumor cells. The study found that ecDNA actively replicates and is stably maintained in ecDNA-positive cells, triggering the ATM-mediated DDR pathway.
Researchers discovered temperature influences plant cell fate by regulating epigenetic marks. Low ambient temperatures can rescue developmental defects by compensating for PRC2 loss, highlighting the importance of H3K27me3 in maintaining cellular identity.
A research team developed a novel strategy to balance high catalytic activity and durability under industrial-level conditions. They constructed a MOF@POM superstructure that undergoes an in-situ transformation into a single-layer CoFe hydroxide catalyst, exhibiting exceptional performance in alkaline electrolytes.
Researchers developed a biomimetic COF membrane that selectively separates lithium ions from complex brines, achieving selectivity comparable to biological ion channels. The membrane's unique structure and design enable efficient single-step purification of lithium, making it a promising route for sustainable extraction.
Researchers have found that mice can instinctively exhibit rescue-like behavior toward anesthetized conspecifics without prior training or external rewards. Oxytocin neurons in the paraventricular nucleus are activated when detecting distress signals, releasing OXT and coordinating emotional and motor responses.
Researchers found that human activity, including military conquests and agricultural practices, led to the sudden collapse of swamp forests in the Pearl River Delta region around 2.1 thousand years ago. This event marked the beginning of a decline in biodiversity, contributing to local extinctions of various species.
A pangenome study has constructed an unprecedented map of wild and cultivated rice, decoding the genetic architecture and diversity of rice. The researchers found 3.87 billion base pairs of novel genetic sequences absent from the single acknowledged reference genome, as well as 69,531 genes spanning the pangenome.
Chinese scientists enhance adhesion of top layers to improve flexible tandem solar cells' performance by utilizing an antisolvent-seeding strategy. The new approach resulted in a stable efficiency of 24.6%, one of the highest reported values for flexible thin-film solar cells.
Researchers developed ZTE materials that nearly restore voltage recovery in aging lithium-ion batteries, doubling battery lifespan. The innovation also sheds light on self-healing function design of high-performance devices.
Researchers have uncovered the molecular mechanism of ATG-9 in regulating lysosome integrity by modulating phospholipid distribution. This study suggests that reduced ATG-9 scramblase activity facilitates lysosome biogenesis and repair, highlighting ATG-9 as a promising therapeutic target for diseases related to lysosomal dysfunction.
Researchers develop novel synthesis method for multi-shelled gold clusters and precisely remove atoms to study magnetic spin influence on catalytic behavior. They find that spin density concentrates more on iodine atoms than sulfur atoms, indicating potential role in tuning catalytic properties.
A study reveals the critical role of α-synuclein's fuzzy coat in its pathological transmission, with implications for disease progression and potential therapeutic targets. The researchers identified two structural variants of α-synuclein fibrils, which differ in their dynamic nature and ability to seed new aggregates.
A Chinese Academy of Sciences research team has identified the first mechanism of citrus resistance to citrus greening disease and developed an AI-assisted therapeutic approach. The discovery addresses the challenge of naturally occurring resistant genes in citrus, offering hope for global agricultural sustainability.
The discovery of Jurassic fossil acanthocephalan Juracanthocephalus provides crucial reference for understanding evolutionary innovations and body plan of thorny-headed worms. It suggests that acanthocephalans may have originated in terrestrial environments and diverged from Rotifera no later than the Middle Jurassic.
Chinese scientists have discovered that the Moon's farside mantle contains less water than the nearside, according to analysis of basalts collected by the Chang'e-6 mission. The research team found a significant disparity in water content between the two hemispheres, mirroring lunar surface asymmetries.
Researchers have developed a novel semiconductor material that significantly improves the efficiency of photocatalytic water splitting by eliminating charge recombination and facilitating efficient charge separation. The Sc-doped TiO2 semiconductor achieves a record-breaking quantum yield of 30.3% and a solar-to-hydrogen efficiency of ...
The study reveals conserved neural patterning mechanisms in mammalian hypothalamus development, tracing how brain cells emerge from neural progenitors during growth. The researchers identified four adaptive evolutionary divergences in human neurons, including a unique subtype and enhanced neuromodulation.
Researchers developed a new ultrafine platinum-based high-entropy alloy octahedra catalyst that enhances methanol oxidation reaction activity and durability. The senary alloy outperformed ternary alloys and commercial platinum-on-carbon catalysts in terms of performance, offering a promising advance for direct methanol fuel cells.
A research team has discovered microglia in the peripheral nervous system (PNS) that regulate neuronal soma size throughout evolution. The study challenges long-held beliefs about microglia's absence from the PNS, revealing a common molecular signature and role in regulating neuron size.
A new study reveals that breast cancer cells exploit the amino acid arginine to drive aggressive tumor behavior and resistance to immunotherapies. Cancer cells act as 'arginine factories,' saturating the tumor microenvironment with this nutrient, which is then used by immune cells to suppress cancer-fighting CD8+ T cells.
Researchers developed a new theory to explain metal-support interactions in single-atom catalysis, achieving high activity and stability in hydrogenation reactions. The Frontier Molecular Orbital (FMO) theory predicts that reducing support size increases LUMO energy, promoting hybridization and enhancing catalytic activity.
A team of scientists has discovered that the circadian clock plays a crucial role in regulating F. oxysporum's response to zinc starvation and controlling secondary metabolism, enhancing its virulence. The study provides new insight into host-pathogen interactions and could lead to innovative approaches for crop protection.
A new study has revealed that Beagle dogs carrying mutations in the Shank3 gene exhibit face processing abnormalities, similar to those observed in human ASD patients. The research provides direct experimental evidence that mutations in Shank3 lead to ASD-like deficits in face processing, contributing to social impairments.
A new study reveals that tomato plants adapt to heat stress by delaying shoot apical stem cell development, allowing for stable yields. This redox-controlled mechanism enables the plant to temporarily suspend its maturation program during adverse conditions, resulting in significant yield losses prevention.
A team of Chinese researchers identified a novel intercellular signaling mechanism between adipocytes and hepatocytes in endoplasmic reticulum stress response. The study reveals that ceramide, a fat molecule, plays a key role in activating the unfolded protein response pathway in hepatocytes.
Researchers uncover a novel immune mechanism by which wheat tandem kinase proteins (TKPs) combat pathogen invasion, establishing a new paradigm for cooperation between TKPs and NLR proteins. The discovery offers a foundation for engineering crop varieties with broad-spectrum pathogen resistance.
A multidisciplinary study reveals Middle Paleolithic Quina technology in East Asia, dating back to approximately 60,000-50,000 years ago. The discovery suggests potential Neanderthal dispersal into Southwest China and reshapes the understanding of East Asia's evolutionary landscape.
Researchers at USTC identify a novel approach to preventing acute graft-versus-host disease (aGVHD) in allo-HSCT by considering the recipient's circadian rhythms. Infusing stem cells early in the day can efficiently reduce the incidence and severity of aGVHD.